Loss of Stemness, EMT, and Supernumerary Tooth Formation in Cebpb-/-Runx2+/- Murine Incisors.

abstract：:Recently, it has been shown that under pressure, unexpected and counterintuitive chemical compounds become stable. Laser shock experiments (A. Rode, unpublished) on alumina (Al2O3) have shown non-equilibrium decomposition of alumina with the formation of free Al and a mysterious transparent phase. Inspired by these ob...

journal_title：Scientific reports

authors： Liu Y,Oganov AR,Wang S,Zhu Q,Dong X,Kresse G

更新日期：2015-04-01 00:00:00

abstract：:The charge transport properties of hybrid halide perovskites are investigated with a combination of density functional theory including van der Waals interaction and the Boltzmann theory for diffusive transport in the relaxation time approximation. We find the mobility of electrons to be in the range 5-10 cm(2)V(-1)s(...

journal_title：Scientific reports

authors： Motta C,El-Mellouhi F,Sanvito S

更新日期：2015-08-03 00:00:00

abstract：:Human group-specific component protein (Gc protein) is a multifunctional serum protein which has three common allelic variants, Gc1F, Gc1S and Gc2 in humans. Gc1 contains an O-linked trisaccharide [sialic acid-galactose-N-acetylgalactosamine (GalNAc)] on the threonine420 (Thr420) residue and can be converted to a pote...

journal_title：Scientific reports

authors： Nabeshima Y,Abe C,Kawauchi T,Hiroi T,Uto Y,Nabeshima YI

更新日期：2020-11-05 00:00:00

abstract：:LytR-cpsA-Psr (LCP) domain containing proteins fulfil important functions in bacterial cell wall synthesis. In Mycobacterium tuberculosis complex (Mtbc) strains, the causative agents of tuberculosis (TB), the genes Rv3484 and Rv3267 encode for LCP proteins which are putatively involved in arabinogalactan transfer to p...

journal_title：Scientific reports

authors： Malm S,Maaß S,Schaible UE,Ehlers S,Niemann S

更新日期：2018-03-02 00:00:00

abstract：:Maonan nationality is a relatively conservative and isolated minority in China. Little is known about the association of the Slit-Robo Rho GTPase activating protein 2 gene (SRGAP2) single nucleotide polymorphisms (SNPs) and serum lipid levels in the Chinese populations. This study was performed to clarify the associat...

journal_title：Scientific reports

authors： Miao L,Yin RX,Wu JZ,Yang S,Lin WX,Pan SL

更新日期：2017-09-14 00:00:00

abstract：:Whale shark (Rhincodon typus) tourism is increasingly popular at predictable aggregations around the world, but only a few use provisioning to ensure close interactions. Understanding the effects of provisioning on the behaviour of this endangered species is critical to manage this growing industry. We recorded the di...

journal_title：Scientific reports

authors： Araujo G,Labaja J,Snow S,Huveneers C,Ponzo A

更新日期：2020-10-12 00:00:00

abstract：:Routine antimicrobial susceptibility testing (AST) can prevent deaths due to bacteria and reduce the spread of multi-drug-resistance, but cannot be regularly performed in resource-limited-settings due to technological challenges, high-costs, and lack of trained professionals. We demonstrate an automated and cost-effec...

journal_title：Scientific reports

authors： Feng S,Tseng D,Di Carlo D,Garner OB,Ozcan A

更新日期：2016-12-15 00:00:00

abstract：:Neuroinflammation in utero may result in life-long neurological disabilities. Microglia play a pivotal role, but the mechanisms are poorly understood. No early postnatal treatment strategies exist to enhance neuroprotective potential of microglia. We hypothesized that agonism on α7 nicotinic acetylcholine receptor (α7...

journal_title：Scientific reports

authors： Cortes M,Cao M,Liu HL,Moore CS,Durosier LD,Burns P,Fecteau G,Desrochers A,Barreiro LB,Antel JP,Frasch MG

更新日期：2017-09-06 00:00:00

abstract：:Creating and maintaining precipitates coherent with the host matrix, under service conditions is one of the most effective approaches for successful development of alloys for high temperature applications; prominent examples include Ni- and Co-based superalloys and Al alloys. While ferritic alloys are among the most i...

journal_title：Scientific reports

authors： Hu YJ,Li J,Darling KA,Wang WY,VanLeeuwen BK,Liu XL,Kecskes LJ,Dickey EC,Liu ZK

更新日期：2015-07-02 00:00:00

abstract：:Recent studies have elucidated the crucial role for microRNAs in peripheral nerve myelination by ablating components of the microRNA synthesis machinery. Few studies have focused on the role of individual microRNAs. To fill this gap, we focused this study on miR-138, which was shown to be drastically reduced in Dicer1...

journal_title：Scientific reports

authors： Lin HP,Oksuz I,Svaren J,Awatramani R

更新日期：2018-02-28 00:00:00

abstract：:The human pathogen Legionella pneumophila delivers a large array of the effector proteins into host cells using the Dot/Icm type IVB secretion system. Among the proteins composing the Dot/Icm system, an inner membrane protein DotI is known to be crucial for the secretion function but its structure and role in type IV ...

journal_title：Scientific reports

authors： Kuroda T,Kubori T,Thanh Bui X,Hyakutake A,Uchida Y,Imada K,Nagai H

更新日期：2015-06-03 00:00:00

abstract：:One of the potential antibiofilm strategies is to use lytic phages and phage-derived polysaccharide depolymerases. The idea is to uncover bacteria embedded in the biofilm matrix making them accessible and vulnerable to antibacterials and the immune system. Here we present the antibiofilm efficiency of lytic phage KP34...

journal_title：Scientific reports

authors： Latka A,Drulis-Kawa Z

更新日期：2020-11-23 00:00:00

abstract：:Shikimate is a key intermediate in the synthesis of neuraminidase inhibitors. Compared with traditional methods, microbial production of shikimate has the advantages of environmental friendliness, low cost, feed stock renewability, and product selectivity and diversity. Despite these advantages, shikimate kinase I and...

journal_title：Scientific reports

authors： Gu P,Su T,Wang Q,Liang Q,Qi Q

更新日期：2016-07-13 00:00:00

abstract：:Current anti-influenza therapy depends on administering drugs soon after infection, which is often impractical. We assessed whether combinations of oseltamivir (a neuraminidase inhibitor) and T-705 (a nonspecific inhibitor of viral polymerases) could extend the window for treating lethal infection with highly pathogen...

journal_title：Scientific reports

authors： Marathe BM,Wong SS,Vogel P,Garcia-Alcalde F,Webster RG,Webby RJ,Najera I,Govorkova EA

更新日期：2016-05-25 00:00:00

abstract：:Global biodiversity hotspots (GBHs) are increasingly vulnerable to human stressors such as anthropogenic climate change, which will alter the ecology of these habitats, even where protected. The longleaf pine (Pinus palustris) ecosystem (LPE) of the North American Coastal Plain is a GBH where disturbances are integral...

journal_title：Scientific reports

authors： Zampieri NE,Pau S,Okamoto DK

更新日期：2020-05-21 00:00:00

abstract：:The gene encoding the cytosolic β-glucosidase GBA3 shows pseudogenization due to a truncated allele (rs358231) that is polymorphic in humans. Since this enzyme is involved in the transformation of many plant β-glycosides, this particular case of gene loss may have been influenced by dietary adaptations during evolutio...

journal_title：Scientific reports

authors： Lopes-Marques M,Serrano C,Cardoso AR,Salazar R,Seixas S,Amorim A,Azevedo L,Prata MJ

更新日期：2020-07-14 00:00:00

abstract：:Quantification of cellular antigens and their interactions via antibody-based detection methods are widely used in scientific research. Accurate high-throughput quantitation of these assays using general image analysis software can be time consuming and challenging, particularly when attempted by users with limited im...

journal_title：Scientific reports

authors： Law AMK,Yin JXM,Castillo L,Young AIJ,Piggin C,Rogers S,Caldon CE,Burgess A,Millar EKA,O'Toole SA,Gallego-Ortega D,Ormandy CJ,Oakes SR

更新日期：2017-11-16 00:00:00

abstract：:Maternal obesity in pregnancy increases the risk of adverse long-term health outcomes in both mother and offspring. A population-based cohort of prospectively collected routine antenatal healthcare data collected between January 2003 and September 2017 at University Hospital Southampton, UK was utilised to investigate...

journal_title：Scientific reports

authors： Ziauddeen N,Roderick PJ,Macklon NS,Alwan NA

更新日期：2019-06-24 00:00:00

abstract：:Nacre, the gold standard for biomimicry, provides an excellent example and guideline for assembling high-performance composites. Inspired by the layered structure and extraordinary strength and toughness of natural nacre, nacre-like nanolignocellulose/poly (vinyl alcohol)/TiO2 composites possessed the similar layered ...

journal_title：Scientific reports

authors： Chen Y,Wang H,Dang B,Xiong Y,Yao Q,Wang C,Sun Q,Jin C

更新日期：2017-05-12 00:00:00

abstract：:The Malay people are an important ethnic composition in Southeast Asia, but their genetic make-up and population structure remain poorly studied. Here we conducted a genome-wide study of four geographical Malay populations: Peninsular Malaysian Malay (PMM), Singaporean Malay (SGM), Indonesian Malay (IDM) and Sri Lanka...

journal_title：Scientific reports

authors： Deng L,Hoh BP,Lu D,Saw WY,Twee-Hee Ong R,Kasturiratne A,Janaka de Silva H,Zilfalil BA,Kato N,Wickremasinghe AR,Teo YY,Xu S

更新日期：2015-09-23 00:00:00

abstract：:Enterovirus A71 (EV-A71), which belongs to the family Picornaviridae, can invade the central nervous system (CNS) and cause severe CNS complications or death. The EV-A71 antigen has been detected in the neurons in the brains of humans who died from EV-A71 infection. However, the effect of EV-A71 infection on human neu...

journal_title：Scientific reports

authors： Lin JY,Huang HI

更新日期：2020-09-17 00:00:00

abstract：:Waddlia chondrophila is a Gram-negative intracellular bacterial organism that is related to classical chlamydial species and has been implicated as a cause of abortion in cattle. Despite an increasing number of observational studies linking W. chondrophila infection to cattle abortion, little direct experimental evide...

journal_title：Scientific reports

authors： Wheelhouse N,Flockhart A,Aitchison K,Livingstone M,Finlayson J,Flachon V,Sellal E,Dagleish MP,Longbottom D

更新日期：2016-11-14 00:00:00

abstract：:Most of the human genome is non-coding. However, some of the non-coding part is transcriptionally active. In humans, the tandemly repeated (TR) pericentromeric non-coding DNA-human satellites 2 and 3 (HS2, HS3)-are transcribed in somatic cells. These transcripts are also found in pre- and post-implantation embryos. Th...

journal_title：Scientific reports

authors： Dobrynin MA,Korchagina NM,Prjibelski AD,Shafranskaya D,Ostromyshenskii DI,Shunkina K,Stepanova I,Kotova AV,Podgornaya OI,Enukashvily NI

更新日期：2020-11-12 00:00:00

abstract：:Ultra-high resolution optical coherence tomography (UHR-OCT) can image the corneal epithelium and Bowman's layer and measurement the thicknesses. The purpose of this study was to validate the diagnostic power of vertical thickness profiles of the corneal epithelium and Bowman's layer imaged by UHR-OCT in the diagnosis...

journal_title：Scientific reports

authors： Xu Z,Jiang J,Yang C,Huang S,Peng M,Li W,Cui L,Wang J,Lu F,Shen M

更新日期：2016-08-11 00:00:00

abstract：:In this paper we applied transfer learning techniques for image recognition, automatic categorization, and labeling of nanoscience images obtained by scanning electron microscope (SEM). Roughly 20,000 SEM images were manually classified into 10 categories to form a labeled training set, which can be used as a referenc...

journal_title：Scientific reports

authors： Modarres MH,Aversa R,Cozzini S,Ciancio R,Leto A,Brandino GP

更新日期：2017-10-16 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep40037. ...

journal_title：Scientific reports

authors： Serena M,Parolini F,Biswas P,Sironi F,Blanco Miranda A,Zoratti E,Scupoli MT,Ziglio S,Valenzuela-Fernandez A,Gibellini D,Romanelli MG,Siccardi A,Malnati M,Beretta A,Zipeto D

更新日期：2018-05-22 00:00:00

abstract：:Photoreceptor function is impaired in many retinal diseases like age-related macular degeneration. Currently, assessment of the photoreceptor function for the early diagnosis and monitoring of these diseases is either subjective, as in visual field testing, requires contact with the eye, like in electroretinography, o...

journal_title：Scientific reports

authors： Messner A,Werkmeister RM,Seidel G,Stegmann H,Schmetterer L,Aranha Dos Santos V

更新日期：2019-09-20 00:00:00

abstract：:Genes central to drug absorption, distribution, metabolism and elimination (ADME) also regulate numerous endogenous molecules. The Remote Sensing and Signaling Hypothesis argues that an ADME gene-centered network-including SLC and ABC "drug" transporters, "drug" metabolizing enzymes (DMEs), and regulatory genes-is ess...

journal_title：Scientific reports

authors： Rosenthal SB,Bush KT,Nigam SK

更新日期：2019-08-15 00:00:00

abstract：:Differences in the pathogenesis and clinical characteristics between lamellar macular hole (LMH) with and without LMH-associated epiretinal proliferation (LHEP) can have surgical implications. This study investigated the effects of treating LHEP by foveolar internal limiting membrane (ILM) non-peeling and epiretinal p...

journal_title：Scientific reports

authors： Ho TC,Ho AY,Chen MS

更新日期：2019-11-05 00:00:00

abstract：:The bacterial stringent response is a key regulator of bacterial virulence, biofilm formation and antibiotic tolerance, and is a promising target for the development of new antibacterial compounds. The intracellular nucleotide (p)ppGpp acts as a messenger orchestrating the stringent response. A synthetic peptide 1018 ...

journal_title：Scientific reports

authors： Andresen L,Tenson T,Hauryliuk V

更新日期：2016-11-07 00:00:00