Abstract:
:Photoreceptor function is impaired in many retinal diseases like age-related macular degeneration. Currently, assessment of the photoreceptor function for the early diagnosis and monitoring of these diseases is either subjective, as in visual field testing, requires contact with the eye, like in electroretinography, or relies on research prototypes with acquisition speeds unattained by conventional imaging systems. We developed an objective, noncontact method to monitor photoreceptor function using a standard optical coherence tomography system. This method can be used with various white light sources for stimulation. The technique was applied in five volunteers and detected a decrease of volume of the subretinal space associated with light adaptation processes of the retina.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Messner A,Werkmeister RM,Seidel G,Stegmann H,Schmetterer L,Aranha Dos Santos Vdoi
10.1038/s41598-019-50057-8subject
Has Abstractpub_date
2019-09-20 00:00:00pages
13632issue
1issn
2045-2322pii
10.1038/s41598-019-50057-8journal_volume
9pub_type
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