Post-Smallpox Vaccination Skin Eruption in a Marine.

Abstract:

:This case report examines a vesiculopustular reaction which occurred in a young Marine 9 d after receiving the smallpox vaccination. Review of the CDC guidelines, ACAM2000 package insert, and literature surrounding the smallpox vaccine reveals several well-established adverse cutaneous reactions associated with vaccination. These dermatologic reactions are typically mild and self-limited, but do have the potential to be life threatening - especially in those with immunocompromise. Unfortunately, the correct diagnosis can often be difficult to make, as many of these rashes share similar characteristics. Furthermore, the low overall incidence of some exanthema associated with the smallpox vaccination makes familiarization with these rashes difficult for the primary provider. This case report includes a review of the associated literature and seeks to offer the clinician some familiarity of the skin eruptions associated with the smallpox vaccination. Self-limited skin eruptions such as autoinoculation, nonviral pustulosis, and generalized vaccinia will be distinguished from the more serious eczema vaccinatum, and from the potentially life-threatening progressive vaccinia.

journal_name

Mil Med

journal_title

Military medicine

authors

Kramer TR

doi

10.1093/milmed/usx133

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

e649-e653

issue

9-10

eissn

0026-4075

issn

1930-613X

pii

4931755

journal_volume

183

pub_type

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