A tomato MADS-box protein, SlCMB1, regulates ethylene biosynthesis and carotenoid accumulation during fruit ripening.

Abstract:

:The MADS-box transcription factors play essential roles in many physiological and biochemical processes of plants, especially in fruit ripening. Here, a tomato MADS-box gene, SlCMB1, was isolated. SlCMB1 expression declined with the fruit ripening from immature green to B + 7 (7 days after Breaker) fruits in the wild type (WT) and was lower in Nr and rin mutants fruits. Tomato plants with reduced SlCMB1 mRNA displayed delayed fruit ripening, reduced ethylene production and carotenoid accumulation. The ethylene production in SlCMB1-RNAi fruits decreased by approximately 50% as compared to WT. The transcripts of ethylene biosynthesis genes (ACS2, ACS4, ACO1 and ACO3), ethylene-responsive genes (E4, E8 and ERF1) and fruit ripening-related genes (RIN, TAGL1, FUL1, FUL2, LoxC and PE) were inhibited in SlCMB1-RNAi fruits. The carotenoid accumulation was decreased and two carotenoid synthesis-related genes (PSY1 and PDS) were down-regulated while three lycopene cyclase genes (CYCB, LCYB and LCYE) were up-regulated in transgenic fruits. Furthermore, yeast two-hybrid assay showed that SlCMB1 could interact with SlMADS-RIN, SlMADS1, SlAP2a and TAGL1, respectively. Collectively, these results indicate that SlCMB1 is a new component to the current model of regulatory network that regulates ethylene biosynthesis and carotenoid accumulation during fruit ripening.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Zhang J,Hu Z,Yao Q,Guo X,Nguyen V,Li F,Chen G

doi

10.1038/s41598-018-21672-8

subject

Has Abstract

pub_date

2018-02-21 00:00:00

pages

3413

issue

1

issn

2045-2322

pii

10.1038/s41598-018-21672-8

journal_volume

8

pub_type

杂志文章
  • Identification of Urine Metabolites as Biomarkers of Early Lyme Disease.

    abstract::Metabolites detectible in human biofluids are attractive biomarkers for the diagnosis of early Lyme disease (ELD), a vector-borne infectious disease. Urine represents an easily obtained clinical sample that can be applied for diagnostic purposes. However, few studies have explored urine for biomarkers of ELD. In this ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29713-y

    authors: Pegalajar-Jurado A,Fitzgerald BL,Islam MN,Belisle JT,Wormser GP,Waller KS,Ashton LV,Webb KJ,Delorey MJ,Clark RJ,Molins CR

    更新日期:2018-08-15 00:00:00

  • Strengthening of graphene aerogels with tunable density and high adsorption capacity towards Pb2+.

    abstract::Graphene aerogels (GAs) with high mechanical strength, tunable density and volume have been prepared only via soaking graphene hydrogels (GHs) in ammonia solution. The density and volume of the obtained GAs are controlled by adjusting the concentration of ammonia solution. Although volume of the GAs decreases with inc...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep05025

    authors: Han Z,Tang Z,Shen S,Zhao B,Zheng G,Yang J

    更新日期:2014-05-22 00:00:00

  • Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia.

    abstract::The semantic variant of primary progressive aphasia (svPPA) is a clinical syndrome characterized by neurodegeneration and progressive loss of semantic knowledge. Unlike many other forms of frontotemporal lobar degeneration (FTLD), svPPA has a highly consistent underlying pathology composed of TDP-43 (a regulator of RN...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-46415-1

    authors: Bonham LW,Steele NZR,Karch CM,Broce I,Geier EG,Wen NL,Momeni P,Hardy J,Miller ZA,Gorno-Tempini ML,Hess CP,Lewis P,Miller BL,Seeley WW,Manzoni C,Desikan RS,Baranzini SE,Ferrari R,Yokoyama JS,International FTD-Genomic

    更新日期:2019-07-26 00:00:00

  • Characterization of photocatalytic TiO2 powder under varied environments using near ambient pressure X-ray photoelectron spectroscopy.

    abstract::Consecutive eight study phases under the successive presence and absence of UV irradiation, water vapor, and oxygen were conducted to characterize surface changes in the photocatalytic TiO2 powder using near-ambient-pressure X-ray photoelectron spectroscopy (XPS). Both Ti 2p and O 1s spectra show hysteresis through th...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep43298

    authors: Krishnan P,Liu M,Itty PA,Liu Z,Rheinheimer V,Zhang MH,Monteiro PJ,Yu LE

    更新日期:2017-02-27 00:00:00

  • Formation and stability of complex metallic phases including quasicrystals explored through combinatorial methods.

    abstract::Aluminum-based quasicrystals typically form across narrow composition ranges within binary to quaternary alloys, which makes their fabrication and characterization challenging. Here, we use combinatorial approaches together with fast characterization techniques to study a wide compositional range including known quasi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-43666-w

    authors: Wolf W,Kube SA,Sohn S,Xie Y,Cha JJ,Scanley BE,Kiminami CS,Bolfarini C,Botta WJ,Schroers J

    更新日期:2019-05-09 00:00:00

  • The green microalga Tetraselmis suecica reduces oxidative stress and induces repairing mechanisms in human cells.

    abstract::Green microalgae contain many active pigments such as carotenoids having antioxidant and protective activity on human cells. Here we investigate the biological activity of an ethanol/water extract of the marine green microalga Tetraselmis suecica containing high levels of carotenoids such as the xanthophylls lutein, v...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41215

    authors: Sansone C,Galasso C,Orefice I,Nuzzo G,Luongo E,Cutignano A,Romano G,Brunet C,Fontana A,Esposito F,Ianora A

    更新日期:2017-01-24 00:00:00

  • Cynomolgus macaque IL37 polymorphism and control of SIV infection.

    abstract::The association between gene polymorphisms and plasma virus load at the set point (SP-PVL) was investigated in Mauritian macaques inoculated with SIV. Among 44 macaques inoculated with 50 AID50, six individuals were selected: three with SP-PVL among the highest and three with SP-PVL among the lowest. The exons of 390 ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44235-x

    authors: Shiina T,Suzuki S,Congy-Jolivet N,Aarnink A,Garchon HJ,Dereuddre-Bosquet N,Vaslin B,Tchitchek N,Desjardins D,Autran B,Lambotte O,Theodorou I,Le Grand R,Blancher A

    更新日期:2019-05-28 00:00:00

  • Effects of Ni doping on various properties of NbH phases: A first-principles investigation.

    abstract::Changes in the stability, hydrogen diffusion, and mechanical properties of the NbH phases from Ni-doping was studied by using first-principles methods. The calculation results reveal that the single H atom adsorption is energetically favorable at the tetrahedral interstitial site (TIS) and octahedral interstitial site...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-06658-2

    authors: Wu Y,Wang Z,Wang D,Wan Z,Zhong Y,Hu C,Zhou H

    更新日期:2017-07-26 00:00:00

  • YebC, a putative transcriptional factor involved in the regulation of the proteolytic system of Lactobacillus.

    abstract::The proteolytic system of Lactobacillus plays an essential role in bacterial growth, contributes to the flavor development of fermented products, and can release bioactive health-beneficial peptides during milk fermentation. In this work, a genomic analysis of all genes involved in the proteolytic system of L. delbrue...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-09124-1

    authors: Brown L,Villegas JM,Elean M,Fadda S,Mozzi F,Saavedra L,Hebert EM

    更新日期:2017-08-17 00:00:00

  • Vertical-type two-dimensional hole gas diamond metal oxide semiconductor field-effect transistors.

    abstract::Power semiconductor devices require low on-resistivity and high breakdown voltages simultaneously. Vertical-type metal-oxide-semiconductor field-effect transistors (MOSFETs) meet these requirements, but have been incompleteness in diamond. Here we show vertical-type p-channel diamond MOSFETs with trench structures and...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-28837-5

    authors: Oi N,Inaba M,Okubo S,Tsuyuzaki I,Kageura T,Onoda S,Hiraiwa A,Kawarada H

    更新日期:2018-07-13 00:00:00

  • Revealing nutritional requirements of MICP-relevant Sporosarcina pasteurii DSM33 for growth improvement in chemically defined and complex media.

    abstract::Microbial induced calcite precipitation (MICP) based on ureolysis has a high potential for many applications, e.g. restoration of construction materials. The gram-positive bacterium Sporosarcina pasteurii is the most commonly used microorganism for MICP due to its high ureolytic activity. However, Sporosarcina pasteur...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-79904-9

    authors: Lapierre FM,Schmid J,Ederer B,Ihling N,Büchs J,Huber R

    更新日期:2020-12-31 00:00:00

  • Establishment of a long-term stable β-cell line and its application to analyze the effect of Gcg expression on insulin secretion.

    abstract::A pancreatic β-cell line MIN6 was previously established in our lab from an insulinoma developed in an IT6 transgenic mouse expressing the SV40 T antigen in β-cells. This cell line has been widely used for in vitro analysis of β-cell function, but tends to lose the mature β-cell features, including glucose-stimulated ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-79992-7

    authors: Miyazaki S,Tashiro F,Tsuchiya T,Sasaki K,Miyazaki JI

    更新日期:2021-01-12 00:00:00

  • A meta-analysis of gene expression data highlights synaptic dysfunction in the hippocampus of brains with Alzheimer's disease.

    abstract::Since the world population is ageing, dementia is going to be a growing concern. Alzheimer's disease is the most common form of dementia. The pathogenesis of Alzheimer's disease is extensively studied, yet unknown remains. Therefore, we aimed to extract new knowledge from existing data. We analysed about 2700 upregula...

    journal_title:Scientific reports

    pub_type: 杂志文章,meta分析

    doi:10.1038/s41598-020-64452-z

    authors: Hosseinian S,Arefian E,Rakhsh-Khorshid H,Eivani M,Rezayof A,Pezeshk H,Marashi SA

    更新日期:2020-05-20 00:00:00

  • Comparative computational analysis of pluripotency in human and mouse stem cells.

    abstract::Pluripotent cells can be subdivided into two distinct states, the naïve and the primed state, the latter being further advanced on the path of differentiation. There are substantial differences in the regulation of pluripotency between human and mouse, and in humans only stem cells that resemble the primed state in mo...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep07927

    authors: Ernst M,Abu Dawud R,Kurtz A,Schotta G,Taher L,Fuellen G

    更新日期:2015-01-21 00:00:00

  • Species-Specific Marker Discovery in Tilapia.

    abstract::Tilapias (family Cichlidae) are of importance in aquaculture and fisheries. Hybridisation and introgression are common within tilapia genera but are difficult to analyse due to limited numbers of species-specific genetic markers. We tested the potential of double digested restriction-site associated DNA (ddRAD) sequen...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-48339-2

    authors: Syaifudin M,Bekaert M,Taggart JB,Bartie KL,Wehner S,Palaiokostas C,Khan MGQ,Selly SC,Hulata G,D'Cotta H,Baroiller JF,McAndrew BJ,Penman DJ

    更新日期:2019-09-10 00:00:00

  • Isotopic ratios of uranium and caesium in spherical radioactive caesium-bearing microparticles derived from the Fukushima Dai-ichi Nuclear Power Plant.

    abstract::Spherical radioactive caesium (Cs)-bearing microparticles (CsMPs) were emitted during the Fukushima Dai-ichi Nuclear Power Plant (FDNPP) accident in March, 2011. The emission source (timing) and formation process of these particles remain unclear. In this study, the isotopic ratios of uranium (235U and 238U) and caesi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-59933-0

    authors: Kurihara Y,Takahata N,Yokoyama TD,Miura H,Kon Y,Takagi T,Higaki S,Yamaguchi N,Sano Y,Takahashi Y

    更新日期:2020-02-24 00:00:00

  • Citric Acid Enhanced Copper Removal by a Novel Multi-amines Decorated Resin.

    abstract::Cu removal by a novel multi-amines decorated resin (PAMD) from wastewater in the absence or presence of citric acid (CA) was examined. Adsorption capacity of Cu onto PAMD markedly increased by 186% to 5.07 mmol/g in the presence of CA, up to 7 times of that onto four commercial resins under the same conditions. Preloa...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep09944

    authors: Ling C,Liu F,Pei Z,Zhang X,Wei M,Zhang Y,Zheng L,Zhang J,Li A,Xing B

    更新日期:2015-05-12 00:00:00

  • Silibinin, A Natural Blend In Polytherapy Formulation For Targeting Cd44v6 Expressing Colon Cancer Stem Cells.

    abstract::Colon cancer stem cells have been attributed to poor prognosis, therapeutic resistance and aggressive nature of the malignancy. Recent reports associated CD44v6 expression with relapse, metastasis and reduced 5-year survival of colon cancer patients, thereby making it a potential therapeutic target. Thus, in this stud...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-35069-0

    authors: Patel S,Waghela B,Shah K,Vaidya F,Mirza S,Patel S,Pathak C,Rawal R

    更新日期:2018-11-19 00:00:00

  • Study of the Binding Energies between Unnatural Amino Acids and Engineered Orthogonal Tyrosyl-tRNA Synthetases.

    abstract::We utilized several computational approaches to evaluate the binding energies of tyrosine (Tyr) and several unnatural Tyr analogs, to several orthogonal aaRSes derived from Methanocaldococcus jannaschii and Escherichia coli tyrosyl-tRNA synthetases. The present study reveals the following: (1) AutoDock Vina and ROSETT...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep12632

    authors: Ren W,Truong TM,Ai HW

    更新日期:2015-07-29 00:00:00

  • Joining Chemical Pressure and Epitaxial Strain to Yield Y-doped BiFeO3 Thin Films with High Dielectric Response.

    abstract::BiFeO3 is one of the most promising multiferroic materials but undergoes two major drawbacks: low dielectric susceptibility and high dielectric loss. Here we report high in-plane dielectric permittivity (ε' ∼2500) and low dielectric loss (tan δ < 0.01) obtained on Bi0.95Y0.05FeO3 films epitaxially grown on SrTiO3 (001...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25535

    authors: Scarisoreanu ND,Craciun F,Birjega R,Ion V,Teodorescu VS,Ghica C,Negrea R,Dinescu M

    更新日期:2016-05-09 00:00:00

  • Archetypal transcriptional blocks underpin yeast gene regulation in response to changes in growth conditions.

    abstract::The transcriptional responses of yeast cells to diverse stresses typically include gene activation and repression. Specific stress defense, citric acid cycle and oxidative phosphorylation genes are activated, whereas protein synthesis genes are coordinately repressed. This view was achieved from comparative transcript...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-26170-5

    authors: Talavera D,Kershaw CJ,Costello JL,Castelli LM,Rowe W,Sims PFG,Ashe MP,Grant CM,Pavitt GD,Hubbard SJ

    更新日期:2018-05-21 00:00:00

  • The proper use of coronary calcium score and coronary computed tomography angiography for screening asymptomatic patients with cardiovascular risk factors.

    abstract::Early detection and treatment of coronary artery disease (CAD) can reduce incidences of acute myocardial infarction. In this study, we determined the proper use of contributing risk factors and coronary artery calcium score (CACS) when screening asymptomatic patients with coronary arterial stenoses using coronary comp...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-17655-w

    authors: Tay SY,Chang PY,Lao WT,Lin YC,Chung YH,Chan WP

    更新日期:2017-12-15 00:00:00

  • Improved antitumor activity of TRAIL fusion protein via formation of self-assembling nanoparticle.

    abstract::Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been known as a promising agent for cancer therapy due to its specific apoptosis-inducing effect on tumor cells rather than most normal cells. However, systemically delivered TRAIL suffers from a rapid clearance from the body with an extremely short h...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41904

    authors: Huang K,Duan N,Zhang C,Mo R,Hua Z

    更新日期:2017-02-22 00:00:00

  • Smoking and alcohol drinking in relation to the risk of esophageal squamous cell carcinoma: A population-based case-control study in China.

    abstract::Previous results regarding the associations between esophageal squamous-cell carcinoma (ESCC) risk and smoking/alcohol drinking in high-risk areas are inconsistent. We performed a large population-based case-control study from 2010 to 2013 in a high-incidence area of China, and enrolled 1353 ESCC cases and 1961 contro...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-17617-2

    authors: Yang X,Chen X,Zhuang M,Yuan Z,Nie S,Lu M,Jin L,Ye W

    更新日期:2017-12-08 00:00:00

  • Generation of Customizable Micro-wavy Pattern through Grayscale Direct Image Lithography.

    abstract::With the increasing amount of research work in surface studies, a more effective method of producing patterned microstructures is highly desired due to the geometric limitations and complex fabricating process of current techniques. This paper presents an efficient and cost-effective method to generate customizable mi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep21621

    authors: He R,Wang S,Andrews G,Shi W,Liu Y

    更新日期:2016-02-23 00:00:00

  • Carbon: nitrogen stoichiometry following afforestation: a global synthesis.

    abstract::Though carbon (C): nitrogen (N) stoichiometry has been widely studied in terrestrial ecosystems, little is known about its variation following afforestation. By synthesizing the results of 53 studies, we examined temporal and spatial variation in C: N ratios and in N-C scaling relationships of both the organic and the...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19117

    authors: Xu X,Li D,Cheng X,Ruan H,Luo Y

    更新日期:2016-01-08 00:00:00

  • Microglia retard dengue virus-induced acute viral encephalitis.

    abstract::Patients with dengue virus (DENV) infection may also present acute viral encephalitis through an unknown mechanism. Here, we report that encephalitic DENV-infected mice exhibited progressive hunchback posture, limbic seizures, limbic weakness, paralysis, and lethality 7 days post-infection. These symptoms were accompa...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep27670

    authors: Tsai TT,Chen CL,Lin YS,Chang CP,Tsai CC,Cheng YL,Huang CC,Ho CJ,Lee YC,Lin LT,Jhan MK,Lin CF

    更新日期:2016-06-09 00:00:00

  • Alignment-free method for DNA sequence clustering using Fuzzy integral similarity.

    abstract::A larger amount of sequence data in private and public databases produced by next-generation sequencing put new challenges due to limitation associated with the alignment-based method for sequence comparison. So, there is a high need for faster sequence analysis algorithms. In this study, we developed an alignment-fre...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-40452-6

    authors: Saw AK,Raj G,Das M,Talukdar NC,Tripathy BC,Nandi S

    更新日期:2019-03-06 00:00:00

  • Interplay between 3'-UTR polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk of ischemic stroke.

    abstract::Stroke incidence is a multifactorial disease and especially hyperhomocysteinemia is associated with a higher risk of stroke. Previous studies have reported a folate metabolism disorder associated with the MTHFR gene. We investigated four single nucleotide polymorphisms in the MTHFR 3'-UTR [2572 C > A (rs4846049), 4869...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-12668-x

    authors: Kim JO,Park HS,Ryu CS,Shin JW,Kim J,Oh SH,Kim OJ,Kim NK

    更新日期:2017-09-29 00:00:00

  • Selection of a novel DNA aptamer against OFA/iLRP for targeted delivery of doxorubicin to AML cells.

    abstract::The standard treatment for most acute myeloid leukemia (AML) is chemotherapy, which is often associated with severe adverse effects. One strategy to reduce the adverse effects is targeted therapy that can selectively deliver anticancer drugs to tumor cells. Immature laminin receptor protein (OFA/iLRP) is a potential t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-43910-3

    authors: An Y,Hu Y,Li X,Li Z,Duan J,Yang XD

    更新日期:2019-05-14 00:00:00