Breast cancer extent and survival among diabetic women in a Finnish nationwide cohort study.

abstract：:Occupational exposures were assessed in a case-control study on testicular cancer using self-administered questionnaires. In total, answers were obtained for 148 (91%) cases and 315 (87%) controls. Of the cases, 101 had seminoma and 47 had embryonal testicular cancer. An increased odds ratio (OR) was found for exposur...

journal_title：International journal of cancer

authors： Hardell L,Ohlson CG,Fredrikson M

更新日期：1997-12-10 00:00:00

abstract：:Oral leukoplakia is a heterogeneous lesion with risk of cancer development; there are no biomarkers to predict its potential of malignant transformation. Tissue proteomic analysis of oral leukoplakia using iTRAQ labeling liquid chromatography-mass spectrometry showed overexpression of heterogeneous ribonucleoprotein K...

journal_title：International journal of cancer

authors： Matta A,Tripathi SC,DeSouza LV,Grigull J,Kaur J,Chauhan SS,Srivastava A,Thakar A,Shukla NK,Duggal R,DattaGupta S,Ralhan R,Michael Siu KW

更新日期：2009-09-15 00:00:00

abstract：:The effect of blockade of NF-kappaB activity on human pancreatic cancer angiogenesis was determined in an orthotopic xenograft model. Highly metastatic L3.3 human pancreatic cancer cells, which expressed an elevated level of constitutive NF-kappaB activity, were transfected with a mutated IkappaBalpha (IkappaBalphaM)....

journal_title：International journal of cancer

authors： Xiong HQ,Abbruzzese JL,Lin E,Wang L,Zheng L,Xie K

更新日期：2004-01-10 00:00:00

abstract：:The effect that polymorphonuclear leukocytes (PMN) may have on the metastatic colonization of tumor cells is controversial: some laboratories have reported that PMN can inhibit metastasis whereas others have shown an augmentation effect. We have exploited our finding that a particular fibrosarcoma (BMT-11) transplante...

journal_title：International journal of cancer

authors： Ishikawa M,Koga Y,Hosokawa M,Kobayashi H

更新日期：1986-06-15 00:00:00

abstract：:The role of retinoic acid receptor (RAR) expression in sensitivity to N-(4-hydroxyphenyl)retinamide (4HPR or fenretinide) as well as on the tumorigenicity of human ovarian carcinoma cells was examined. Two human ovarian cancer cell lines, A2780 and IGROV-1, with a 10-fold difference in sensitivity to 4HPR were chosen ...

journal_title：International journal of cancer

authors： Pergolizzi R,Appierto V,Crosti M,Cavadini E,Cleris L,Guffanti A,Formelli F

更新日期：1999-05-31 00:00:00

abstract：:Pathological deregulation of the transforming growth factor, beta 1 (TGFB1) pathway has been implicated in the development of several major diseases, including cancers. Regulatory variation in the TGFB1 gene may lead to altered TGFB1 expression and activity, and thus, modulate an individual's susceptibility to disease...

journal_title：International journal of cancer

authors： Healy J,Dionne J,Bélanger H,Larivière M,Beaulieu P,Labuda D,Sinnett D

更新日期：2009-09-15 00:00:00

abstract：:Rat yolk-sac tumors were induced by intraperitoneal (i.p.) displacement of the visceral yolk sac in fetectomized W/Fu rats. Serum was obtained from each female rat prior to the pregnancy preceding the tumor-inducing procedure and then once a month during the induction period. The sera were analyzed for the presence of...

journal_title：International journal of cancer

authors： Lindvall ML,Alumets J,Sjögren HO

更新日期：1987-07-15 00:00:00

abstract：:Laser scanning confocal microscopy has been used to follow the uptake and efflux of the 2-fluoroglycoside of doxorubicin, ME2303, in live cultures of the human ovarian cancer cell line A2780 and its doxorubicin-resistant variant A2780AD. Our methods combine confocal laser scanning microscopy and image analysis to exam...

journal_title：International journal of cancer

authors： Huxham IM,Barlow AL,Lewis AD,Plumb J,Mairs RJ,Gaze MN,Workman P

更新日期：1994-10-01 00:00:00

abstract：:Nuclear factor-κB (NF-κB) is constitutively activated in many cancers, including oral squamous cell carcinoma (OSCC), and is involved in the invasive characteristics of OSCC, such as growth, antiapoptotic activity and protease production. However, the cellular mechanism underlying NF-κB's promotion of bone invasion by...

journal_title：International journal of cancer

authors： Furuta H,Osawa K,Shin M,Ishikawa A,Matsuo K,Khan M,Aoki K,Ohya K,Okamoto M,Tominaga K,Takahashi T,Nakanishi O,Jimi E

更新日期：2012-09-01 00:00:00

abstract：:Renal cell cancer (RCC) has become a prototype example of the extensive intratumor heterogeneity and clonal evolution of human cancers. However, there is little direct evidence on how the genetic heterogeneity impacts on drug response profiles of the cancer cells. Our goal was to determine how genomic clonal evolution...

journal_title：International journal of cancer

authors： Saeed K,Ojamies P,Pellinen T,Eldfors S,Turkki R,Lundin J,Järvinen P,Nisen H,Taari K,Af Hällström TM,Rannikko A,Mirtti T,Kallioniemi O,Östling P

更新日期：2019-03-15 00:00:00

abstract：:Paraffin sections from 190 epithelial ovarian tumours, including 159 malignant and 31 benign epithelial tumours, were analysed immunohistochemically for expression of cyclin-dependent kinase inhibitor 2 (CDKN2A) gene product p16INK4A (p16). Most benign tumours showed no p16 expression in the tumour cells, whereas only...

journal_title：International journal of cancer

authors： Dong Y,Walsh MD,McGuckin MA,Gabrielli BG,Cummings MC,Wright RG,Hurst T,Khoo SK,Parsons PG

更新日期：1997-02-20 00:00:00

abstract：:We have established a number of cell lines from Merkel cell carcinoma (MCC) of the skin. In many respects these cell lines resemble those established from small cell lung cancer (SCLC) and it is difficult to differentiate between metastatic MCC and SCLC on morphological or histochemical criteria. Both are thought to b...

journal_title：International journal of cancer

authors： Thomson JA,Leonard JH,McGregor K,Sturm RA,Parsons PG

更新日期：1994-07-15 00:00:00

abstract：:There are no reliable serologic tumor markers for transitional cell carcinoma (TCC) of the urinary bladder and noninvasive urine investigations are inadequate. We used fluorescent microsatellite analysis (MSA) to detect serum DNA and urine-sediment DNA alterations in patients with bladder cancer and prospectively coll...

journal_title：International journal of cancer

authors： von Knobloch R,Hegele A,Brandt H,Olbert P,Heidenreich A,Hofmann R

更新日期：2001-10-01 00:00:00

abstract：:von Willebrand factor (vWF), a glycoprotein produced uniquely by endothelial cells and megakaryocytes, is routinely used to identify vessels in tissue sections. Vessel density in tumor specimens, as determined by immuno-histochemical staining for vWF or other endothelial cell markers, is a negative prognostic factor f...

journal_title：International journal of cancer

authors： Zanetta L,Marcus SG,Vasile J,Dobryansky M,Cohen H,Eng K,Shamamian P,Mignatti P

更新日期：2000-01-15 00:00:00

abstract：:Trilaciclib is an intravenous CDK4/6 inhibitor administered prior to chemotherapy to preserve haematopoietic stem and progenitor cells and immune system function from chemotherapy-induced damage (myelopreservation). The effects of administering trilaciclib prior to carboplatin, etoposide and atezolizumab (E/P/A) were ...

journal_title：International journal of cancer

authors： Daniel D,Kuchava V,Bondarenko I,Ivashchuk O,Reddy S,Jaal J,Kudaba I,Hart L,Matitashvili A,Pritchett Y,Morris SR,Sorrentino JA,Antal JM,Goldschmidt J

更新日期：2020-12-21 00:00:00

abstract：:Several observational epidemiological studies have reported inconsistent results on the association between the use of benzodiazepine and the risk of cancer. We investigated the association by using a meta-analysis. We searched PubMed, EMBASE, and the bibliographies of relevant articles to locate additional publicatio...

journal_title：International journal of cancer

authors： Kim HB,Myung SK,Park YC,Park B

更新日期：2017-02-01 00:00:00

abstract：:MET is a master gene controlling a genetic program driving proliferation, apoptosis protection and invasion. The ROR1 pseudokinase acts as a MET substrate. However, its contribution to MET signaling and MET-dependent biological outcomes remains to be elucidated. By structure-function analysis of ROR1 mutants, we show ...

journal_title：International journal of cancer

authors： Gentile A,Lazzari L,Benvenuti S,Trusolino L,Comoglio PM

更新日期：2014-11-15 00:00:00

abstract：:Little research has been conducted on the long-term value of human papillomavirus (HPV) testing after conization. We investigated whether cytology adds to the value of a negative HPV test for long-term prediction of cervical intraepithelial neoplasia grade 2 or worse (CIN2+). In addition, we compared risk of CIN2+ fol...

journal_title：International journal of cancer

authors： Gosvig CF,Huusom LD,Andersen KK,Duun-Henriksen AK,Frederiksen K,Iftner A,Svare E,Iftner T,Kjaer SK

更新日期：2015-12-15 00:00:00

abstract：:Several mouse models studying the MLL fusion-induced leukemic transformation showed that a myeloproliferation stage precedes leukemia or occurred as the only phenotype of hematological disorder in mice. We established 6 MLL/AF10(OM-LZ)-immortalized cell lines by retrovirally transducing the fusion gene into bone marro...

journal_title：International journal of cancer

authors： Fu JF,Hsu CL,Shih LY

更新日期：2010-04-01 00:00:00

abstract：:Sex steroid hormones influence prostate development and maintenance through their roles in prostate cellular proliferation, differentiation and apoptosis. Although suspected to be involved in prostate carcinogenesis, an association between circulating androgens and prostate cancer has not been clearly established in e...

journal_title：International journal of cancer

authors： Weiss JM,Huang WY,Rinaldi S,Fears TR,Chatterjee N,Hsing AW,Crawford ED,Andriole GL,Kaaks R,Hayes RB

更新日期：2008-05-15 00:00:00

abstract：:The effect of serum from mice bearing methylcholanthrene-induced fibrosarcomas on the lympho-proliferative responses of their spleen and lymph-node cells to 3 M KCl-solubilized tumor antigens has been investigated. Low concentrations of serum (less than or equal to 2.5%) collected throughout the course of tumor growth...

journal_title：International journal of cancer

authors： Calderwood MB,Forbes JT,Smith RT

更新日期：1977-09-15 00:00:00

abstract：:Nitric oxide may serve as one cofactor for human papillomavirus (HPV)-induced development of cervical cancer. Therefore, we first assessed the levels of cervical fluid nitric oxide metabolite (NOx) in 283 women with and without high-risk (hr) HPV. The NOx level in women with hr HPV (48.4 μmol/L [95% CI: 39.4-56.6], n ...

journal_title：International journal of cancer

authors： Rahkola P,Väisänen-Tommiska M,Tuomikoski P,Ylikorkala O,Mikkola TS

更新日期：2011-06-15 00:00:00

abstract：:We evaluated RS5444, a thiazolidinedione high affinity PPARgamma agonist, for the ability to inhibit colon carcinogenesis in azoxymethane (AOM)-treated mice. In our initial experiment, mice were treated with RS5444 during AOM treatment, and the drug was withdrawn 12 weeks after the last injection of AOM. RS5444 signif...

journal_title：International journal of cancer

authors： Su W,Necela BM,Fujiwara K,Kurakata S,Murray NR,Fields AP,Thompson EA

更新日期：2008-09-01 00:00:00

abstract：:Several lines of evidence suggest that long-term treatment with non-steroidal anti-inflammatory drugs may reduce the risk of colon cancer and the size and number of colonic polyps in patients with familial adenomatous polyposis. Aspirin has also been shown to inhibit cell proliferation in human tumor cell lines and to...

journal_title：International journal of cancer

authors： Ricchi P,Pignata S,Di Popolo A,Memoli A,Apicella A,Zarrilli R,Acquaviva AM

更新日期：1997-12-10 00:00:00

abstract：:The role of miRNAs with tumor suppressive activity in liver cancer has been well studied. However, little is known about potential oncomiRs in HCC. In our study, we conducted a systematic evaluation of candidate oncomiRs and found that upregulation of miR-18a and miR-25 in HCC was associated with poor patient survival...

journal_title：International journal of cancer

authors： Sanchez-Mejias A,Kwon J,Chew XH,Siemens A,Sohn HS,Jing G,Zhang B,Yang H,Tay Y

更新日期：2019-01-15 00:00:00

abstract：:By transmission and scanning electron microscopic studies of MC-29 virus-infected CEC cultures, C-type virus particles were detected in the medium of infected cultures, in infected cells and in intracellular vacuoles. Virus budding was also observed. In the scanning electron microscope (SEM) so-called blebs appeared o...

journal_title：International journal of cancer

authors： Podmaniczky E,Szende B,Lapis K,Ferenc G

更新日期：1976-10-15 00:00:00

abstract：:Although several studies have investigated the association of miRNAs with hepatocellular carcinoma (HCC), the data published so far are not concordant. A reason for these discrepancies may be the fact that most studies used the nontumorous tissue surrounding the HCC lesion as a control, which is almost invariably affe...

journal_title：International journal of cancer

authors： Diaz G,Melis M,Tice A,Kleiner DE,Mishra L,Zamboni F,Farci P

更新日期：2013-08-15 00:00:00

abstract：:A challenging task of the immune system is to fight cancer cells. However, a variety of human cancers educate immune cells to become tumor supportive. This is exemplified for tumor-associated macrophages (TAMs), which are polarized towards an anti-inflammatory and cancer promoting phenotype. Mechanistic explanations, ...

journal_title：International journal of cancer

authors： Weigert A,Schiffmann S,Sekar D,Ley S,Menrad H,Werno C,Grosch S,Geisslinger G,Brüne B

更新日期：2009-11-01 00:00:00

abstract：:Laboratory and epidemiological data have linked vitamin D to breast cancer prevention. Beside dietary intake, endogenous production of vitamin D substantially contributes to a subject's vitamin D status. Most studies, however, have assessed dietary intake only. Although differential effects of vitamin D on premenopaus...

journal_title：International journal of cancer

authors： Abbas S,Chang-Claude J,Linseisen J

更新日期：2009-01-01 00:00:00

abstract：:Recent epidemiological investigations have reported on the association between telomere length (TL) and a number of malignancies, including B-cell lymphoma (BCL). The reported results for BCLs are however inconsistent. We carried out a nested case-control study to determine whether TL is associated with future risk of...

journal_title：International journal of cancer

authors： Hosnijeh FS,Matullo G,Russo A,Guarrera S,Modica F,Nieters A,Overvad K,Guldberg P,Tjønneland A,Canzian F,Boeing H,Aleksandrova K,Trichopoulou A,Lagiou P,Trichopoulos D,Tagliabue G,Tumino R,Panico S,Palli D,Olsen KS,

更新日期：2014-12-15 00:00:00