Neuronal apoptosis inhibitory protein is implicated in amyotrophic lateral sclerosis symptoms.

abstract：:Systemic antioxidative status has been implicated in glaucoma pathogenesis. Additionally, corneal hysteresis (CH) may contribute to glaucoma progression. Here, we evaluated the relationship between biological antioxidant potential (BAP) and CH. This study included 103 patients with open-angle glaucoma (OAG). We used a...

journal_title：Scientific reports

authors： Uchida K,Himori N,Hashimoto K,Shiga Y,Tsuda S,Omodaka K,Nakazawa T

更新日期：2020-01-17 00:00:00

abstract：:The present work focuses on the dynamical aspects of cross-reactivity between myelin based protein (MBP) self-peptide and two microbial peptides (UL15, PMM) for Hy.1B11 T-cell receptor (TCR). This same TCR was isolated from a patient suffering from multiple sclerosis (MS). The study aims at highlighting the chemical i...

journal_title：Scientific reports

authors： Kumar A,Delogu F

更新日期：2017-02-14 00:00:00

abstract：:An infinite three dimensional (3D) crystal can be constructed by an infinite number of parallel 2D (hkl) crystal planes (CPs) coupled to each other. Based on lattice model Hamiltonian with the hopping between the nearest neighbor (1NN) CPs and all possible neighbor hoppings within each CP, we analytically prove that a...

journal_title：Scientific reports

authors： Wang H,Gao T,Tao R

更新日期：2015-03-02 00:00:00

abstract：:Elevated prostaglandin E2 (PGE2) levels are observed in colorectal cancer (CRC) patients, and this increase is associated with poor prognosis. Increased synthesis of PGE2 in CRC has been shown to occur through COX-2-dependent mechanisms; however, loss of the PGE2-catabolizing enzyme, 15-hydroxyprostaglandin dehydrogen...

journal_title：Scientific reports

authors： Monteleone NJ,Moore AE,Iacona JR,Lutz CS,Dixon DA

更新日期：2019-04-01 00:00:00

abstract：:We have assembled the complete sequence of the Durio zibethinus chloroplast genome using long PacBio reads. Durian is a valuable commercial tree that produces durian fruit, which is popular in Southeast Asia. The chloroplast genome assembled into a single 143 kb cyclic contig that contained 111 genes. There were 46 sh...

journal_title：Scientific reports

authors： Shearman JR,Sonthirod C,Naktang C,Sangsrakru D,Yoocha T,Chatbanyong R,Vorakuldumrongchai S,Chusri O,Tangphatsornruang S,Pootakham W

更新日期：2020-10-07 00:00:00

abstract：:We demonstrate that the microstructural and mechanical properties of bacterial biofilms can be created through colloidal self-assembly of cells and polymers, and thereby link the complex material properties of biofilms to well understood colloidal and polymeric behaviors. This finding is applied to soften and disassem...

journal_title：Scientific reports

authors： Stewart EJ,Ganesan M,Younger JG,Solomon MJ

更新日期：2015-08-14 00:00:00

abstract：:Telomerase is expressed in adult mouse, but not in most human, tissues and mouse telomeres are much longer than those in humans. This interspecies difference of telomere homeostasis poses a challenge in modeling human diseases using laboratory mice. Using chromatinized bacterial artificial chromosome reporters, we dis...

journal_title：Scientific reports

authors： Cheng,Zhao Y,Zhang F,Zhang J,Wang S,Zhu J

更新日期：2019-07-04 00:00:00

abstract：:Generating various laser sources is important in the communication systems. We propose an approach that uses a mechanical resonator coupled with the optical fibre system to produce periodic and chaotic optical signals. The resonator is structured in such a way that the nonlinear oscillation occurs conveniently. The me...

journal_title：Scientific reports

authors： Jin L,Guo Y,Ji X,Li L

更新日期：2017-07-06 00:00:00

abstract：:Multiple applications of genome editing by CRISPR-Cas9 necessitate stringent regulation and Cas9 variants have accordingly been generated whose activity responds to small ligands, temperature or light. However, these approaches are often impracticable, for example in clinical therapeutic genome editing in situ or gene...

journal_title：Scientific reports

authors： Suzuki T,Asami M,Patel SG,Luk LYP,Tsai YH,Perry ACF

更新日期：2018-07-03 00:00:00

abstract：:The rat is an important model for liver regeneration. However, there is no in vitro culture system that can capture the massive proliferation that can be observed after partial hepatectomy in rats. We here describe the generation of rat liver stem cell lines. Rat liver stem cells, which grow as cystic organoids, were ...

journal_title：Scientific reports

authors： Kuijk EW,Rasmussen S,Blokzijl F,Huch M,Gehart H,Toonen P,Begthel H,Clevers H,Geurts AM,Cuppen E

更新日期：2016-02-26 00:00:00

abstract：:Recruitment is one of the dominant processes regulating fish population productivity. It is, however, notoriously difficult to predict, as it is the result of a complex multi-step process. Various fine-scale drivers might act on the pathway from adult population characteristics to spawning behaviour and egg production...

journal_title：Scientific reports

authors： Brosset P,Smith AD,Plourde S,Castonguay M,Lehoux C,Van Beveren E

更新日期：2020-09-30 00:00:00

abstract：:Spectroscopic techniques combined with chemometrics methods have proven to be effective tools for the discrimination of objects with similar properties. In this work, terahertz time-domain spectroscopy (THz-TDS) combined with discriminate analysis (DA) and principal component analysis (PCA) with derivative pretreatmen...

journal_title：Scientific reports

authors： Xu W,Xie L,Ye Z,Gao W,Yao Y,Chen M,Qin J,Ying Y

更新日期：2015-07-08 00:00:00

abstract：:We have investigated the emission from InGaN/GaN quantum disks grown on the tip of GaN nanorods. The emission at 3.21 eV from the InGaN quantum disk doesn't show a Stark shift, and it is linearly polarized when excited perpendicular to the growth direction. The degree of linear polarization is about 39.3% due to the a...

journal_title：Scientific reports

authors： Park Y,Chan CCS,Nuttall L,Puchtler TJ,Taylor RA,Kim N,Jo Y,Im H

更新日期：2018-05-25 00:00:00

abstract：:The therapeutic effects of C16, which is an inhibitor of RNA-dependent protein kinase (PKR), on growth of hepatocellular carcinoma (HCC) cells and tumor progression in vitro and in vivo were evaluated. Huh7 cells, a human HCC cell line, were used. The effects of C16 on cell viability were evaluated with the MTT assay,...

journal_title：Scientific reports

authors： Watanabe T,Ninomiya H,Saitou T,Takanezawa S,Yamamoto S,Imai Y,Yoshida O,Kawakami R,Hirooka M,Abe M,Imamura T,Hiasa Y

更新日期：2020-03-20 00:00:00

abstract：:Unimpaired readers process words incredibly fast and hence it was assumed that top-down processing, such as predicting upcoming words, would be too slow to play an appreciable role in reading. This runs counter the major postulate of the predictive coding framework that our brain continually predicts probable upcoming...

journal_title：Scientific reports

authors： Hawelka S,Schuster S,Gagl B,Hutzler F

更新日期：2015-02-13 00:00:00

abstract：:We examined whether it is possible to identify individual subjects on the basis of brain anatomical features. For this, we analyzed a dataset comprising 191 subjects who were scanned three times over a period of two years. Based on FreeSurfer routines, we generated three datasets covering 148 anatomical regions (corti...

journal_title：Scientific reports

authors： Valizadeh SA,Liem F,Mérillat S,Hänggi J,Jäncke L

更新日期：2018-04-04 00:00:00

abstract：:Soil microorganisms play a crucial role in the biogeochemical cycling of nutrient elements and maintaining soil health. We aimed to investigate the response of bacteria communities to organic farming over different crops (rice, tea and vegetable) along the middle and lower reaches of the Yangtze River of China. Compar...

journal_title：Scientific reports

authors： Wang W,Wang H,Feng Y,Wang L,Xiao X,Xi Y,Luo X,Sun R,Ye X,Huang Y,Zhang Z,Cui Z

更新日期：2016-10-11 00:00:00

abstract：:Starting from the dataset of the publication corpus of the APS during the period 1955-2009, we reconstruct the individual researchers trajectories, namely the list of the consecutive affiliations for each scholar. Crossing this information with different geographic datasets we embed these trajectories in a spatial fra...

journal_title：Scientific reports

authors： Gargiulo F,Carletti T

更新日期：2014-05-07 00:00:00

abstract：:A common spinning toy, called "buzzer", consists of a perforated disk and flexible threads. Despite of its simple construction, a buzzer can effectively transfer translational motions into high-speed rotations. In the present work, we find that the disk can be spun by hand at an extremely high rotational speed, e.g., ...

journal_title：Scientific reports

authors： Zhao ZL,Zhou S,Xu S,Feng XQ,Xie YM

更新日期：2017-10-13 00:00:00

abstract：:Forest cutting is a major anthropogenic disturbance that affects forest carbon (C) storage and fluxes. Yet its characteristics and impacts on C cycling are poorly understood over large areas. Using recent annualized forest inventory data, we estimated cutting-related loss of live biomass in the eastern United States w...

journal_title：Scientific reports

authors： Zhou D,Liu S,Oeding J,Zhao S

更新日期：2013-12-19 00:00:00

abstract：:Salvia miltiorrhiza is one of the most widely-used medicinal plants. Here, we systematically analyzed the RNA editing events in its mitochondria. We developed a pipeline using REDItools to predict RNA editing events from stand-specific RNA-Seq data. The predictions were validated using reverse transcription, RT-PCR am...

journal_title：Scientific reports

authors： Wu B,Chen H,Shao J,Zhang H,Wu K,Liu C

更新日期：2017-02-10 00:00:00

abstract：:High throughput genomics technologies are applied widely to microbiomes in humans, animals, soil and water, to detect changes in bacterial communities or the genes they carry, between different environments or treatments. We describe a method to test the statistical significance of differences in bacterial population ...

journal_title：Scientific reports

authors： Shaw LM,Blanchard A,Chen Q,An X,Davies P,Tötemeyer S,Zhu YG,Stekel DJ

更新日期：2019-02-20 00:00:00

abstract：:Nano-flowers reported so far were mostly constituted of inorganic or hybrid materials. We have synthesized and crystallized a new organic compound, 1, 2-bis(tritylthio)ethane forming an organic nano-flower consisting of single crystalline petals. Crystal structure at nano and micro level indicates that π-π stacking in...

journal_title：Scientific reports

authors： Sasidharan S,P C S,Chaudhary N,Ramakrishnan V

更新日期：2017-12-11 00:00:00

abstract：:Uterus transplantation (UTx) is a potential option for women with uterine factor infertility to have a child. The clinical features indicating irreversible rejection of the uterus are unknown. In our experimental series of allogeneic UTx in cynomolgus macaques, six female macaques were retrospectively examined, which ...

journal_title：Scientific reports

authors： Kisu I,Emoto K,Masugi Y,Yamada Y,Matsubara K,Obara H,Matoba Y,Banno K,Kato Y,Saiki Y,Itagaki I,Kawamoto I,Iwatani C,Murase M,Nakagawa T,Tsuchiya H,Ishigaki H,Urano H,Ema M,Ogasawara K,Aoki D,Nakagawa K,Shiina

更新日期：2020-08-17 00:00:00

abstract：:The cartilaginous and non-neopterygian bony fishes have an electric sense typically comprised of hundreds or thousands of sensory canals distributed in broad clusters over the head. This morphology facilitates neural encoding of local electric field intensity, orientation, and polarity, used for determining the positi...

journal_title：Scientific reports

authors： Berquist RM,Galinsky VL,Kajiura SM,Frank LR

更新日期：2015-03-11 00:00:00

abstract：:The selective destruction of large-scale brain networks by pathogenic protein spread is a ubiquitous theme in neurodegenerative disease. Characterising the circuit architecture of these diseases could illuminate both their pathophysiology and the computational architecture of the cognitive processes they target. Howev...

journal_title：Scientific reports

authors： Benhamou E,Marshall CR,Russell LL,Hardy CJD,Bond RL,Sivasathiaseelan H,Greaves CV,Friston KJ,Rohrer JD,Warren JD,Razi A

更新日期：2020-10-01 00:00:00

abstract：:We propose a method to simulate spin models in trapped ions using a digital-analog approach, consisting in a suitable gate decomposition in terms of analog blocks and digital steps. In this way, we show that the quantum dynamics of an enhanced variety of spin models could be implemented with substantially less number ...

journal_title：Scientific reports

authors： Arrazola I,Pedernales JS,Lamata L,Solano E

更新日期：2016-07-29 00:00:00

abstract：:Abscisic acid (ABA) is an ancient stress hormone and is detectable in a wide variety of organisms where it regulates innate immunity and inflammation. Previously, we showed that oral supplementation with ABA decreased parasitemia in a mouse model of malaria, decreased liver and spleen pathology and reduced parasite tr...

journal_title：Scientific reports

authors： Glennon EKK,Megawati D,Torrevillas BK,Ssewanyana I,Huang L,Aweeka F,Greenhouse B,Adams LG,Luckhart S

更新日期：2018-06-11 00:00:00

abstract：:Recent studies have established that single nucleotide polymorphisms are sufficient to build accurate predictive models of gene expression. Gamazon, et al., found that gene expression values predicted from cis neighborhood SNPs show statistical association with disease status. In this work, we remove the cis neighborh...

journal_title：Scientific reports

authors： Vervier K,Michaelson JJ

更新日期：2016-12-20 00:00:00

abstract：:Cortical neural activities lead to changes in the cerebral blood flow (CBF), which involves astrocytic control of cerebrovascular tone. However, the manner in which astrocytic activity specifically leads to vasodilation or vasoconstriction is difficult to determine. Here, cortical astrocytes genetically expressing a l...

journal_title：Scientific reports

authors： Masamoto K,Unekawa M,Watanabe T,Toriumi H,Takuwa H,Kawaguchi H,Kanno I,Matsui K,Tanaka KF,Tomita Y,Suzuki N

更新日期：2015-06-16 00:00:00