Vasoactive intestinal peptide (VIP)-like immunoreactive neurons located in the rat suprachiasmatic nucleus receive a direct retinal projection.

abstract：:We studied the extracellular concentration of glutamate and taurine in the frontal cortex of freely-moving pentylenetetrazole (PTZ) kindled rats using an in vivo microdialysis. A significant and sustained increase in the glutamate level was observed in the kindled rats, in contrast, a slight and delayed increase was o...

journal_title：Neuroscience letters

authors： Li Z,Yamamoto Y,Morimoto T,Ono J,Okada S,Yamatodani A

更新日期：2000-03-17 00:00:00

abstract：:Cholecystokinin (CCK) is suggested to be involved, e.g. in the central nervous modulation of food intake, possibly by acting within specific hypothalamic nuclei. Perinatal overnutrition predisposes to permanent obesity and hyperphagia, while underlying mechanisms are unclear. By reducing the litter size from the 3rd t...

journal_title：Neuroscience letters

authors： Plagemann A,Rake A,Harder T,Melchior K,Rohde W,Dörner G

更新日期：1998-12-11 00:00:00

abstract：:The involvement of glutamate receptors in the central transmission of somatosympathetic reflexes was studied by examining, in anesthetized rats, the effects of MK-801, an N-methyl-D-aspartate (NMDA) receptor antagonist, and CNQX, a non-NMDA receptor antagonist, on two reflex components, the A- and C-reflexes evoked in...

journal_title：Neuroscience letters

authors： Nagata O,Li WM,Sato A

更新日期：1995-12-08 00:00:00

abstract：:Melatonin is the principle hormonal product of the pineal gland. It is secreted with a robust daily rhythm, peaking near the middle of the night. During the daytime, concentrations remain very low, as exposure to light robustly suppresses its secretion. The regulation of melatonin by light is well-characterized, but a...

journal_title：Neuroscience letters

authors： Bedrosian TA,Herring KL,Walton JC,Fonken LK,Weil ZM,Nelson RJ

更新日期：2013-05-10 00:00:00

abstract：:Electroencephalography (EEG) is a non-invasive technique for monitoring electrical activity and has good time resolution. Combining these advantages of EEG with dipole-tracing analysis incorporating a realistic three-layer head model (scalp-skull-brain head model; SSB/DT) allows for the detection of dipoles in the mil...

journal_title：Neuroscience letters

authors： Inoue M,Masaoka Y,Kawamura M,Okamoto Y,Homma I

更新日期：2008-05-30 00:00:00

abstract：:Parkinson's disease (PD) is a progressive neurodegenerative disease. Majority of PD cases are sporadic, resulting from interaction of genetic and environmental factors. Accumulating evidence indicates that autophagy, which delivers alpha-synuclein to lysosomes for degradation, is involved in the PD pathogenesis. Some ...

journal_title：Neuroscience letters

authors： Wu G,Pang S,Feng X,Zhang A,Li J,Gu K,Huang J,Dong H,Yan B

更新日期：2011-08-01 00:00:00

abstract：:To study zinc (Zn) mobility in the rat olfactory tract, brain distribution of 65Zn after injection into the olfactory bulb or amygdaloid nuclei was analyzed by autoradiography. Twenty-four hours after 65Zn injection into the olfactory bulb, 65Zn was distributed in the ipsilateral piriform cortex, amygdaloid nuclei and...

journal_title：Neuroscience letters

authors： Takeda A,Ohnuma M,Sawashita J,Okada S

更新日期：1997-03-28 00:00:00

abstract：:Transcranial magnetic stimulation is a non-invasive tool in clinical diagnostics and therapy for physiological and psychological diseases and has an increased application in experimental neurophysiology. Despite this, the mechanisms of magnetic stimulation of the central nervous system remain still unclear. We applied...

journal_title：Neuroscience letters

authors： Stock M,Kirchner B,Waibler D,Cowley DE,Pfaffl MW,Kuehn R

更新日期：2012-09-27 00:00:00

abstract：:The time-variant quadratic phase coupling (QPC) in trace alternant (TA) EEG patterns in healthy full-term neonates (quiet sleep) was investigated by means of time-variant bispectral analysis. The frequency plain 1-1.5 Hz <=> 3.5-4.5 Hz was used as the region-of-interest. QPC rhythms with a frequency of approximately 0...

journal_title：Neuroscience letters

authors： Schwab K,Putsche P,Eiselt M,Helbig M,Witte H

更新日期：2004-10-21 00:00:00

abstract：:Imaging studies indicate smaller orbitofrontal cortex (OFC) volume in mood disorder patients compared with healthy subjects. We sought to determine whether child and adolescent patients with bipolar disorder have smaller OFC volumes than healthy controls. Fourteen children and adolescents meeting DSM-IV criteria for b...

journal_title：Neuroscience letters

authors： Najt P,Nicoletti M,Chen HH,Hatch JP,Caetano SC,Sassi RB,Axelson D,Brambilla P,Keshavan MS,Ryan ND,Birmaher B,Soares JC

更新日期：2007-02-21 00:00:00

abstract：:The endogenously synthesized nonapeptide arginine vasopressin (AVP) is thought to be involved in transduction of photic information to the pineal gland. The enhancement of circulating AVP leads to a suppression of the nocturnal melatonin surge the mechanisms of which are unknown so far. We therefore studied the effect...

journal_title：Neuroscience letters

authors： Stehle J,Reuss S,Riemann R,Seidel A,Vollrath L

更新日期：1991-02-11 00:00:00

abstract：:The mechanisms responsible for the termination of paroxysmal depolarization shifts (PDS) were studied with intracellular recordings on CA1 neurons of rat hippocampal slices. Epileptiform activity was induced by application of penicillin, bicuculline or Mg-free artificial cerebrospinal fluid (ACSF). PDS in penicillin-c...

journal_title：Neuroscience letters

authors： Domann R,Westerhoff CH,Witte OW

更新日期：1994-07-18 00:00:00

abstract：:Recordings from the intact nervus terminalis with a hook electrode or from a stump of the divided nerve with a suction electrode show a tonic, irregular discharge of broad, low frequency spikes in ca. 4-6 units. These nerve impulses are efferent from the brain. The mean frequency of discharge is not influenced by vari...

journal_title：Neuroscience letters

authors： Bullock TH,Northcutt RG

更新日期：1984-02-10 00:00:00

abstract：:The effects of maternal deprivation (MD) during early postnatal life on the brain-derived neurotrophic factor (BDNF) level were investigated in the present study. Wistar rats were assigned to either maternal deprivation or mother-reared control (MRC) groups. MD manipulation was achieved by separating rat pups from the...

journal_title：Neuroscience letters

authors： Kuma H,Miki T,Matsumoto Y,Gu H,Li HP,Kusaka T,Satriotomo I,Okamoto H,Yokoyama T,Bedi KS,Onishi S,Suwaki H,Takeuchi Y

更新日期：2004-11-30 00:00:00

abstract：:Reduction of non-protein-bound iron (NPBI) using iron chelators may attenuate hypoxia-ischemia-induced reperfusion injury of the brain. This study investigated whether administration of low-dose deferoxamine and allopurinol, both having NPBI-chelating properties, reduced hypoxia-ischemia-induced NPBI formation in plas...

journal_title：Neuroscience letters

authors： Shadid M,Buonocore G,Groenendaal F,Moison R,Ferrali M,Berger HM,van Bel F

更新日期：1998-05-22 00:00:00

abstract：:Horseradish peroxidase (HRP), injected into the rat caudal medulla oblongata, was detected by immunoperoxidase staining in 120 microns frozen sections, allowing examination of both the distribution and morphology of transporting neurons. In the hypothalamus, several groups of HRP-labeled neurons could be distinguished...

journal_title：Neuroscience letters

authors： Sofroniew MV,Schrell U

更新日期：1980-10-02 00:00:00

abstract：:The effects of suppression of postsynaptic density protein 95 (PSD-95) expression on the increased tyrosine phosphorylation of N-methyl-D-aspartate receptor subunit NR2A and interactions of Src and Fyn with NR2A after brain ischemia were investigated by immunoprecipitation and immunoblotting. Transient (15 min) brain ...

journal_title：Neuroscience letters

authors： Hou XY,Zhang GY,Zong YY

更新日期：2003-06-05 00:00:00

abstract：:Since the mRNA level of Fyn, a neurodevelopmental molecule, expression had been reported to be increased in postmortem schizophrenic prefrontal cortex and showed a strong correlation with age of disease onset, we investigated whether the three polymorphisms of the Fyn gene on genomic DNA (-93A/G, IVS10+37T/C and Ex12+...

journal_title：Neuroscience letters

authors： Ohnuma T,Shibata N,Matsubara Y,Sato S,Yamashina M,Arai H

更新日期：2003-05-29 00:00:00

abstract：:Amyloid beta-protein, the major constituent of Alzheimer's disease (AD) brain amyloid deposits, is encoded by several alternatively spliced amyloid precursor protein (APP) mRNAs. The well-established associated in Down's syndrome (DS) between APP overproduction and premature development of AD, as well as the recent de...

journal_title：Neuroscience letters

authors： Ledoux S,Bergeron C,Nalbantoglu J,Gauthier S,Cashman NR

更新日期：1995-06-30 00:00:00

abstract：:Ibotenic acid was injected into 3 parts of the lateral rat hippocampus. The animals were sacrificed 100 days after treatment, and studied immunohistochemically. The lesioned side of the hippocampus was highly atrophic with extensive neuronal loss and gliosis. Although silver staining revealed no particular structures ...

journal_title：Neuroscience letters

authors： Nakamura Y,Takeda M,Niigawa H,Hariguchi S,Nishimura T

更新日期：1992-02-17 00:00:00

abstract：:Nerve ligation injury in rats may represent a useful model of some clinical neuropathic pains. Activation of N-methyl-D-aspartate (NMDA) receptors may maintain central sensitivity and contribute to neuropathic pain. Here, nerve injury was produced by unilateral ligation of the L5 and L6 spinal roots of the sciatic ner...

journal_title：Neuroscience letters

authors： Ossipov MH,Lopez Y,Nichols ML,Bian D,Porreca F

更新日期：1995-10-20 00:00:00

abstract：:Recently, we demonstrated that dimeric apocynin prevented loss of motor function in the leucine-rich repeat kinase 2 (LRRK2(R1441G)) transgenic (tg) mouse (treated with 200mg/kg, three times per week) [B.P. Dranka et al., Neurosci. Lett. 549 (2013) 57-62]. Here we extend those studies by treating LRRK2(R1441G) mice wi...

journal_title：Neuroscience letters

authors： Dranka BP,Gifford A,McAllister D,Zielonka J,Joseph J,O'Hara CL,Stucky CL,Kanthasamy AG,Kalyanaraman B

更新日期：2014-11-07 00:00:00

abstract：:Technologies for wireless telecommunication systems using millimeter waves (MMW) will be widely deployed in the near future. Forthcoming applications in this band, especially around 60GHz, are mainly developed for high data-rate local and body-centric telecommunications. At those frequencies, electromagnetic radiation...

journal_title：Neuroscience letters

authors： Haas AJ,Le Page Y,Zhadobov M,Sauleau R,Le Dréan Y

更新日期：2016-04-08 00:00:00

abstract：:The effects of long-term exposure of primary cultured rat dorsal root ganglion (DRG) cells to bradykinin (BK), compared to short-term exposure, were investigated to establish whether BK could induce prostaglandin E2 (PGE2) release from DRG cells. Short-term exposure (30 min) resulted in a small but significant amount ...

journal_title：Neuroscience letters

authors： Inoue A,Iwasa M,Nishikura Y,Ogawa S,Nakasuka A,Nakata Y

更新日期：2006-07-03 00:00:00

abstract：:MxA protein, one of the GTPases, is induced in the cytoplasm by interferons and confers a high degree of resistance to some viruses. We recently reported that in cases of Parkinson's disease (PD), Lewy bodies (LBs) in the substantia nigra (SN) were positive for MxA. This study aimed to provide more detailed data on Mx...

journal_title：Neuroscience letters

authors： Yamada T

更新日期：1995-07-28 00:00:00

abstract：:The extracellular signal-regulated kinase (ERK) is enriched in the central nervous system, including the dopamine responsive regions such as the striatum and medial prefrontal cortex (mPFC). The kinase is sensitive to changing cellular and synaptic input and is implicated in the regulation of synaptic transmission and...

journal_title：Neuroscience letters

authors： Mao LM,Wang JQ

更新日期：2019-04-23 00:00:00

abstract：:An increasing number of studies support the presence of stem-like cells in human malignancies. These cells are primarily responsible for tumor initiation and thus considered as a potential target to eradicate tumors. CD133 has been identified as an important cell surface marker to enrich the stem-like population in va...

journal_title：Neuroscience letters

authors： Dong L,Qi N,Ge RM,Cao CL,Lan F,Shen L

更新日期：2010-11-05 00:00:00

abstract：:The present study assessed the mechanisms by which nerve growth factor (NGF) increased the level of apolipoprotein E (apoE) in PC12 cells. NGF (50ng/mL) significantly increased apoE protein levels following 72h of treatment. Similarly NGF increased luciferase activity in cells transfected with a luciferase reporter co...

journal_title：Neuroscience letters

authors： Strachan-Whaley MR,Reilly K,Dobson J,Kalisch BE

更新日期：2015-05-19 00:00:00

abstract：:Micro traumatic brain injury (TBI) is the most common type of brain injury, but the mechanisms underlying it are poorly understood. Aquaporin-4 (AQP4) is a water channel expressed in astrocyte end-feet, which plays an important role in brain edema. However, little is known about the role of AQP4 in micro TBI. Here, we...

journal_title：Neuroscience letters

authors： Liang F,Luo C,Xu G,Su F,He X,Long S,Ren H,Liu Y,Feng Y,Pei Z

更新日期：2015-06-26 00:00:00

abstract：:The present study investigated in vivo the kinetic of the changes in rat striatal extracellular concentrations of dopamine (DA), and its monoamine oxidase (MAO)-derived metabolite 3,4-dihydroxyphenylacetic acid (DOPAC), following administration either of nitric oxide (NO) synthase (NOS) inhibitors 7-nitroindazole (7-N...

journal_title：Neuroscience letters

authors： Desvignes C,Bert L,Vinet L,Denoroy L,Renaud B,Lambás-Señas L

更新日期：1999-04-02 00:00:00