Effect of magnetic stimulation on the gene expression profile of in vitro cultured neural cells.

abstract：:To establish a model for functional hyperemia in the rat visual cortex, cortical blood flow responses to flash stimulation were measured with the laser Doppler flow (LDF) technique at various levels of halothane anesthesia. The concentration-dependent effect of halothane on arterial pressure and its consequent effect ...

journal_title：Neuroscience letters

authors： Schulte ML,Hudetz AG

更新日期：2006-02-06 00:00:00

abstract：:Interleukin-18 (IL-18) is a pro-inflammatory cytokine and an important mediator of peripheral inflammation and host immune response. IL-18 functions through its binding with the IL-18 receptor (IL-18R), which consists of two chains, an IL-18-binding α chain (IL-18Rα) and a signaling β chain. IL-18 and IL-18R are expre...

journal_title：Neuroscience letters

authors： Kuwahara-Otani S,Maeda S,Kobayashi K,Minato Y,Tanaka K,Yamanishi K,Hata M,Li W,Hayakawa T,Noguchi K,Okamura H,Yagi H

更新日期：2017-05-22 00:00:00

abstract：:Recent evidence indicates that the N-methyl-D-aspartate (NMDA) receptor-channel complex contains a glycine subunit whose activation may be necessary for channel operation. It has been previously shown that stimulation of the NMDA receptor leads to an increase in intracellular ionic Ca2+ [( Ca2+]i); therefore, we exami...

journal_title：Neuroscience letters

authors： Oliver MW,Shacklock JA,Kessler M,Lynch G,Baimbridge KG

更新日期：1990-07-03 00:00:00

abstract：:Several studies on the relationship between event-related desynchronization/synchronization (ERD/ERS) and cognitive performance revealed contradictory results particularly for the alpha band. Studies from our laboratory have shown that good performers show a larger upper alpha ERD (interpreted in terms of larger corti...

journal_title：Neuroscience letters

authors： Doppelmayr M,Klimesch W,Sauseng P,Hödlmoser K,Stadler W,Hanslmayr S

更新日期：2005-06-24 00:00:00

abstract：:Interleukin-1 beta (IL-1 beta), interleukin-2 (IL-2), and interleukin-6 (IL-6) were measured in the cerebrospinal fluid (CSF) and plasma of 12 control subjects, 11 sporadic Alzheimer's disease (AD) and 22 de novo Parkinson's disease (PD) patients using high sensitivity enzyme-linked immunosorbent assays (ELISA). IL-1 ...

journal_title：Neuroscience letters

authors： Blum-Degen D,Müller T,Kuhn W,Gerlach M,Przuntek H,Riederer P

更新日期：1995-12-29 00:00:00

abstract：:We have conjectured that axons embody a post transcriptional sprouting programme repressed by mature Schwann cells. Injured nerves of Wld(s) mice neither degenerate nor regenerate for several weeks but axons do regrow if the resident cells of the distal stump are destroyed. To test our hypothesis we made an extended c...

journal_title：Neuroscience letters

authors： Iñiguez A,Alvarez J

更新日期：1999-06-18 00:00:00

abstract：:Large-conductance calcium-activated potassium channels (BK channels) have been suggested to play a substantial role in synaptic transmission in the spinal cord dorsal horn. In the present experiments, we attempted to clarify the physiological significance of BK channels in the modulation of synaptic transmission in th...

journal_title：Neuroscience letters

authors： Furukawa N,Takasusuki T,Fukushima T,Hori Y

更新日期：2008-10-17 00:00:00

abstract：:Previously published data have indicated that in the rat, unlike other species examined, the kidney is not supplied by sensory nerves containing substance P (SP). As part of a study of reflex control of renal function in the rat, we have now reassessed this situation. Many fine, varicose, SP-immunoreactive nerve fiber...

journal_title：Neuroscience letters

authors： Ferguson M,Bell C

更新日期：1985-09-30 00:00:00

abstract：:Depressive disorders represent a significant health concern as they are associated with high social and physical dysfunction and increased risk for suicide. Electroconvulsive therapy (ECT) is the most effective treatment for patients with drug-resistant severe depressive disorders. However, the underlying biological m...

journal_title：Neuroscience letters

authors： Fryland T,Elfving B,Christensen JH,Mors O,Wegener G,Børglum AD

更新日期：2012-05-10 00:00:00

abstract：:English /l/ and /r/ sounds are not distinctive for Japanese speakers and they are loosely associated with corresponding graphemes. The purpose of this study was to investigate the brain activities in the memory process for the graphemes containing 'l' and 'r' in Japanese speakers. Two functional magnetic resonance ima...

journal_title：Neuroscience letters

authors： Sumiyoshi C,Matsuo K,Kato C,Ozawa F,Takehara Y,Isoda H,Isogai S,Sakahara H,Nakai T

更新日期：2003-01-09 00:00:00

abstract：:Bis(7)-tacrine [bis(7)-tetrahydroaminacrine] acts as an AChE inhibitor and also exerts modulatory effects on many ligand-gated ion channels and voltage-gated Ca(2+) and K(+) channels. It has been reported previously that tacrine and some other AChE inhibitors suppressed I(K(A)) in central and peripheral neurons. The p...

journal_title：Neuroscience letters

authors： Nie H,Yu WJ,Li XY,Yuan CH,Pang YP,Li CY,Han YF,Li ZW

更新日期：2007-01-29 00:00:00

abstract：:Repeated stress triggers a wide range of adaptive changes in the central nervous system including the elevation of serotonin (5-HT) metabolism and an increased susceptibility to affective disorders. To begin to examine whether these changes are mediated by alterations in gene expression for tryptophan hydroxylase (TPH...

journal_title：Neuroscience letters

authors： Chamas F,Serova L,Sabban EL

更新日期：1999-06-04 00:00:00

abstract：:'Clipsin' and other peptide bond hydrolase activities that appear to be integral membrane proteins, including two implicated in the formation of the histological hallmarks of Alzheimer's disease, were assayed in the frontal and parietal cortex from a large (n = 45) series of postmortem human brains. Tissues were extra...

journal_title：Neuroscience letters

authors： Stratmann GC,Webster MT,Francis PT,Procter AW,Bowen DM

更新日期：1992-08-31 00:00:00

abstract：:In order to clarify the participation of substance P in the expression of opiate withdrawal, we have investigated the effects induced by the new selective neurokinin-1 antagonist RP 67580 on naloxone-induced morphine withdrawal syndrome in rats. Intracerebroventricular administration of RP 67580 elicited a decrease in...

journal_title：Neuroscience letters

authors： Maldonado R,Girdlestone D,Roques BP

更新日期：1993-06-25 00:00:00

abstract：:The contribution of excitatory inputs to CA1 pyramidal cell death after ischemia was examined using rats with unilateral destruction of CA3 pyramidal cells. Intracerebroventricular injection of L-alpha-kainic acid (KA) was performed before the induction of transient forebrain ischemia. Five days after ischemic insult,...

journal_title：Neuroscience letters

authors： Onodera H,Sato G,Kogure K

更新日期：1986-07-24 00:00:00

abstract：:Rhythmic arm movement significantly suppresses H-reflex amplitude in the soleus (SOL) muscle. This is evidence of neural linkages between the arms and legs which can be exploited during locomotion and have been ascribed to the descending effects of CPGs for arm cycling. However, the generalizability of the effects of ...

journal_title：Neuroscience letters

authors： Dragert K,Zehr EP

更新日期：2009-02-06 00:00:00

abstract：:Peroxisome proliferator-activated receptors (PPARs) are ligand-dependent transcription factors which belong to the nuclear receptor family. We examined whether PPARalpha agonists and resveratrol, a polyphenol contained in grapes, protect the brain against ischemia. To investigate whether resveratrol activates PPARs, w...

journal_title：Neuroscience letters

authors： Inoue H,Jiang XF,Katayama T,Osada S,Umesono K,Namura S

更新日期：2003-12-11 00:00:00

abstract：:Odor-induced oscillatory signals have been reported in odor discrimination in various insects. To understand dynamic olfactory coding in the first order olfactory center, the antennal lobe, localization of oscillatory signals was investigated using an optical recording technique with a voltage-sensitive dye. We presen...

journal_title：Neuroscience letters

authors： Okada K,Kanzaki R

更新日期：2001-12-28 00:00:00

abstract：:The present study was carried out to examine whether γ-aminobutyric acid (GABA) receptor mechanisms are involved in the release of serotonin (5-hydroxytryptamine, 5-HT) in the subfornical organ (SFO) using intracerebral microdialysis techniques. Perfusion with the GABA receptor antagonists as well as agonists was perf...

journal_title：Neuroscience letters

authors： Takahashi M,Nomura M,Tanaka J

更新日期：2016-09-06 00:00:00

abstract：:Using high performance liquid chromatography (HPLC) and electrochemical detection, serotonin and its precursor 5-hydroxytryptophan (5-HTP) were identified in crude perchloric acid extracts from bovine cornea. In addition, dopamine, noradrenaline and adrenaline were identified. Through the use of immunohistochemical pr...

journal_title：Neuroscience letters

authors： Osborne NN

更新日期：1983-01-31 00:00:00

abstract：:Fear-conditioned analgesia (FCA) is modulated by brain areas involved in the descending inhibitory pain pathway such as the basolateral (BLA) and central amygdala (CEA). The BLA contains Ca2+/calmodulin-dependent protein kinase II (CaMKII) and parvalbumin (PV) neurons. CEA neurons are primarily inhibitory (GABAergic) ...

journal_title：Neuroscience letters

authors： Butler RK,Ehling S,Barbar M,Thomas J,Hughes MA,Smith CE,Pogorelov VM,Aryal DK,Wetsel WC,Lascelles BDX

更新日期：2017-11-20 00:00:00

abstract：:Basal serotonin (5-HT) release, measured in the presence of imipramine, was significantly reduced in slices of hippocampus, n. accumbens and frontal cortex from rats subjected to forced swim test and chronic isolation. Only in the hippocampus, in the two animal models of depression, K-stimulated release was increased....

journal_title：Neuroscience letters

authors： Jaffe EH,De Frias V,Ibarra C

更新日期：1993-11-12 00:00:00

abstract：:Advanced glycation end products (AGEs) in the brain were immunohistochemically examined in Alzheimer's disease (AD) and aging using anti-AGE antibody recognizing mainly carboxymethyllysine. AGE positive staining diffusely located in the neuronal perikarya of hippocampus and parahippocampus in AD and aged brains withou...

journal_title：Neuroscience letters

authors： Takedo A,Yasuda T,Miyata T,Mizuno K,Li M,Yoneyama S,Horie K,Maeda K,Sobue G

更新日期：1996-12-27 00:00:00

abstract：:To clarify the possible involvement of protein kinase (PK) C activation in the excitation and sensitization of polymodal receptors (PMRs), the effects of phorbol 12,13-dibutyrate (PDBu) on PMRs were studied in canine testis-spermatic nerve preparations in vitro. Application of PDBu (10(-7), 10(-6), AND 10(-5) M) for 5...

journal_title：Neuroscience letters

authors： Leng S,Mizumura K,Koda H,Kumazawa T

更新日期：1996-03-08 00:00:00

abstract：:Basal forebrain (BF) lesions induced by ibotenic acid produced increases in the Bmax and Kd values of [3H]QNB binding sites in the frontal cortex, parietal cortex, and hippocampus. Twenty-eight-day successive administration of propentofylline (10 and 25 mg/kg, p.o.) significantly reduced the Kd values of [3H]QNB bindi...

journal_title：Neuroscience letters

authors： Fuji K,Hiramatsu M,Hayashi S,Kameyama T,Nabeshima T

更新日期：1993-02-05 00:00:00

abstract：:Activation of the medial septum (MS) enhances the synchronized firing of pyramidal cells in the hippocampus. At least two distinct mechanisms might be recruited in this process: GABAergic inhibition of hippocampal inhibitory interneurons and cholinergic enhancement of pyramidal cell excitability. In the present study,...

journal_title：Neuroscience letters

authors： Ovsepian SV

更新日期：2006-01-23 00:00:00

abstract：:Glial cell line-derived neurotrophic factor (GDNF) is produced both in the central nervous system (CNS) and the periphery. Effective in ameliorating neurodegeneration in several animal models of CNS disease, its promise as a therapeutic agent would be greatly enhanced if it readily crossed the blood-brain barrier (BBB...

journal_title：Neuroscience letters

authors： Kastin AJ,Akerstrom V,Pan W

更新日期：2003-04-17 00:00:00

abstract：:Among various kinds of visual motion, wide field coherent visual motion should have characteristic physiological significance regarding the relationship between the external world and us. To detect veridical visual motion in the surrounding environment, specific mechanisms are necessary to differentiate it from the wi...

journal_title：Neuroscience letters

authors： Urakawa T,Inui K,Kakigi R

更新日期：2011-01-25 00:00:00

abstract：:Adenosine and AMP (5'-adenosine monophosphate) applied by microiontophoresis produced depression of neuronal firing rates in cerebral cortex. A number of antidepressant drugs including examples which are known not to affect noradrenaline uptake systems, potentiated the depressant purine effects. Noradrenaline response...

journal_title：Neuroscience letters

authors： Stone TW,Taylor DA

更新日期：1979-01-01 00:00:00

abstract：:Erythropoietin (EPO) and its specific receptor (EPOR) have been proposed to act as an endogenous system protecting against neuronal injury and neurodegeneration. We measured EPO in cerebrospinal fluid (CSF) of patients with neurodegenerative diseases, and tested for a correlation with an established biomarker of neuro...

journal_title：Neuroscience letters

authors： Brettschneider J,Widl K,Ehrenreich H,Riepe M,Tumani H

更新日期：2006-09-01 00:00:00