Abstract：
:Background This study examined the association between cardiac structure and function and the deterioration in activities of daily living (ADLs) in an age-homogenous, community-dwelling population of patients born in 1920-1921 over a five-year follow-up period. Design Longitudinal cohort study. Methods Patients were recruited from the Jerusalem Longitudinal Cohort Study, which has followed an age-homogenous cohort of Jerusalem residents born in 1920-1921. Patients underwent home echocardiography and were followed up for five years. Dependence was defined as needing assistance with one or more basic ADL. Standard echocardiographic assessment of cardiac structure and function, including systolic and diastolic function, was performed. Reassessment of ADLs was performed at the five-year follow-up. Results A total of 459 patients were included in the study. Of these, 362 (79%) showed a deterioration in at least one ADL at follow-up. Patients with functional deterioration had a significantly higher left ventricular mass index and left atrial volume with a lower ejection fraction. There was no significant difference between the diastolic parameters the groups in examined. When the data were examined categorically, a significantly larger percentage of patients with functional decline had an abnormal left ventricular ejection fraction and left ventricular hypertrophy. The association between left ventricular mass index and functional decline remained significant in all multivariate models. Conclusions In this cohort of the oldest old, an elevated left ventricular mass index, higher left atrial volumes and systolic, but not diastolic dysfunction, were predictive of functional disability.
journal_name
Eur J Prev Cardioljournal_title
European journal of preventive cardiologyauthors
Leibowitz D,Jacobs JM,Lande-Stessman I,Gilon D,Stessman Jdoi
10.1177/2047487317744365subject
Has Abstractpub_date
2018-02-01 00:00:00pages
263-269issue
3eissn
2047-4873issn
2047-4881journal_volume
25pub_type
杂志文章abstract：OBJECTIVES:To assess the practices of physicians in 12 European countries in the primary prevention of cardiovascular disease (CVD). METHODS:In 2009, 806 physicians from 12 European countries answered a questionnaire, delivered electronically or by post, regarding their assessment of patients with cardiovascular risk ...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,多中心研究
doi：10.1177/1741826711407705
更新日期：2012-06-01 00:00:00
abstract：AIMS:The European Cardiac Rehabilitation in the Elderly (EU-CaRE) HORIZON 2020 project compares the sustainable effects of cardiac rehabilitation (CR) in elderly patients. METHODS AND RESULTS:A total of 1633 patients with coronary artery disease (CAD) or heart valve replacement (HVR), with or without revascularization...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487320903869
更新日期：2020-11-01 00:00:00
abstract：:Background To assess the association between health-related quality of life (HRQL) and a composite outcome including incident coronary heart disease (CHD) and cerebrovascular events in a large general population-based cohort. Design Prospective analysis on 17,102 men and women (mean age 53 ± 11) free from cardiovascul...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487317748452
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Cardiovascular risk factors are known to be associated between parents and offspring. However, whether these associations are reflected in increased offspring mortality has not been extensively studied. DESIGN:This was a family study of 32,536 father-offspring and 39,614 mother-offspring pairs who participa...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487314562118
更新日期：2016-01-01 00:00:00
abstract：:Exercise-induced ischemic preconditioning (IPC) can be assessed with the second exercise stress test during sequential testing. Exercise-induced IPC is defined as the time to 1 mm ST segment depression (STD), the rate-pressure product (RPP) at 1 mm STD, the maximal ST depression and the rate-pressure product at peak e...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,meta分析,评审
doi：10.1177/2047487313502447
更新日期：2015-01-01 00:00:00
abstract：:The beneficial effect of exercise training and exercise-based cardiac rehabilitation on symptom-free exercise capacity,cardiovascular and skeletal muscle function, quality of life, general healthy lifestyle, and reduction of depressive symptoms and psychosocial stress is nowadays well recognized. However, it remains l...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,评审
doi：10.1177/2047487312437063
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Depression is common after a cardiac event; however it often remains untreated. Previously, we reported the efficacy and feasibility of a 6-month tele-health programme (MoodCare), which integrates depression management into a cardiovascular disease (CVD) risk reduction programme for Acute Coronary Syndrome (...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1177/2047487314547655
更新日期：2015-09-01 00:00:00
abstract：INTRODUCTION:Many different dietary supplements are currently marketed for the management of hypertension and diabetes, but the evidence for effectiveness is mixed. The objective of this systematic review was to critically appraise and evaluate the evidence for effectiveness of steviol glycosides (stevioside and rebaud...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,meta分析,评审
doi：10.1177/2047487314560663
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate the validity and reliability of the HeartQoL instrument in a population of stable coronary patients. DESIGN:Analyses are based on the cross-sectional EUROASPIRE IV (EUROpean Action on Secondary and Primary prevention through Intervention to Reduce Events) survey. ME...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,多中心研究
doi：10.1177/2047487315604837
更新日期：2016-05-01 00:00:00
abstract：AIMS:Recent European guidelines recommend in patients with atherosclerotic cardiovascular disease to achieve a reduction of low-density lipoprotein-cholesterol of at least 50% if the baseline low-density lipoprotein-cholesterol level is between 1.8 and 3.5 mmol/L. Systematic reviews have associated a given statin/dose ...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487319874898
更新日期：2020-10-01 00:00:00
abstract：:Background Epidemiological studies on smoking and atrial fibrillation have been inconsistent, with some studies showing a positive association while others have found no association. It is also unclear whether there is a dose-response relationship between the number of cigarettes smoked or pack-years and the risk of a...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,meta分析
doi：10.1177/2047487318780435
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:The Comparison of Sacubitril-Valsartan versus Enalapril on Effect on NT-proBNP in Patients Stabilised from an Acute Heart Failure Episode (PIONEER-HF) trial demonstrated significant reductions in N-terminal pro-B-type natriuretic peptide. Our study explored the cost-effectiveness of the use of sacubitril-val...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487319878953
更新日期：2019-10-04 00:00:00
abstract：BACKGROUND:The purpose of this study was to evaluate the effect of a physical activity telemonitoring program on daily physical activity level, oxygen uptake capacity (VO(2peak)), and cardiovascular risk profile in coronary artery disease (CAD) patients who completed phase II cardiac rehabilitation (CR). METHODS:Eight...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1177/2047487313514018
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:The prevalence of undetected left ventricular diastolic dysfunction is high, especially in the elderly with comorbidities. Left ventricular diastolic dysfunction is a prognostic indicator of heart failure, in particularly of heart failure with preserved ejection fraction and of future cardiovascular and all-...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487318816774
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:We are unaware of any previous investigation that has compared the relationship of key cardiopulmonary exercise testing (CPX) variables to various measures of pathophysiology between heart failure-reduced ejection fraction (HFrEF) and HF-preserved ejection fraction (HFpEF) cohorts that are well matched with ...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487313476962
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:South Asians presenting with chest pain in the UK experience disproportionately greater delays with respect to diagnosis and treatment for acute myocardial infarction (AMI). The duration of time between symptom onset and hospital intervention is a critical delay for AMI but there are limited data amongst Sou...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487312447844
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Adiponectin is viewed as an insulin-sensitizing hormone with anti-inflammatory effects. In accordance, plasma adiponectin is decreased in metabolic disorders including type 2 diabetes mellitus (T2DM). However, in spite of the apparently beneficially effects, recent data from large prospective studies have co...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487313514894
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Statin intolerance is a barrier to effective lipid-lowering treatment. A significant number of patients stop prescribed statins, or can take only a reduced dose, because of adverse events attributed to the statin, and are then considered statin-intolerant. METHODS:Examination of differences between statin a...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,评审
doi：10.1177/2047487315602861
更新日期：2016-05-01 00:00:00
abstract：:Background In contemporary atrial fibrillation trials most deaths are cardiac related, whereas stroke and bleeding represent only a small subset of deaths. We aimed to evaluate the long-term risk of cardiac events and all-cause mortality in individuals with atrial fibrillation compared to no atrial fibrillation. Desig...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,meta分析,评审
doi：10.1177/2047487317715769
更新日期：2017-09-01 00:00:00
abstract：:Introduction Diabetes and pre-diabetes are highly prevalent in patients with a history of acute coronary syndrome. This is why screening for glucose metabolism disorders is recommended in patients following an acute coronary syndrome. The aim of our study was to determine whether glycated haemoglobin alone compared wi...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487317754011
更新日期：2018-03-01 00:00:00
abstract：:Background Preliminary evidence suggests that peak exercise oxygen pulse - peak oxygen uptake/heart rate-, a variable obtained during maximal cardiopulmonary exercise testing and a surrogate of stroke volume, is a predictor of mortality. We aimed to assess the associations of peak exercise oxygen pulse with sudden car...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487318761679
更新日期：2018-05-01 00:00:00
abstract：AIMS:Air pollution and noise are potential risk factors for subclinical atherosclerosis. Longitudinal analyses, especially on the interplay of these environmental factors, are scarce and inconsistent. Hence we investigated long-term traffic-related exposure to air pollution and noise with the development and progressio...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487319854818
更新日期：2020-06-01 00:00:00
abstract：:Background Chronic Rheumatic Heart disease (RHD) continues to be a health problem in many low and middle income countries and especially in sub-Saharan Africa. Echocardiography has shown that the disease is far more widespread than may be detected by clinical assessment, but data are lacking on the prevalence and epid...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487316687104
更新日期：2017-05-01 00:00:00
abstract：:Background The risk of cardiovascular disease is closely connected to adipose tissue inflammation. The links between cardiovascular risk predictors and pro and anti-inflammatory macrophages in human adipose tissue were analysed to gain an insight into the pathophysiology of cardiovascular disease. Design Subcutaneous ...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487317743355
更新日期：2018-02-01 00:00:00
abstract：:Cancer and cardiovascular diseases are the leading causes of death in high-income countries. Cardiovascular complications can be found in cancer patients, being the result of so-called 'cardio-toxicity'. Therefore, it becomes essential to thoroughly investigate the origin of cardiac damage and the strategy to prevent ...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487319874900
更新日期：2019-10-06 00:00:00
abstract：:Background There are few reviews comparing the long-term outcomes of the use of angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in a hypertensive population because both are effective in reducing blood pressure. None of them compared angiotensin-converting enzyme inhibitors or angiotensin ...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,meta分析,评审
doi：10.1177/2047487317728766
更新日期：2017-12-01 00:00:00
abstract：:There are large variations in the incidence, registration methods and reported causes of sudden cardiac arrest/sudden cardiac death (SCA/SCD) in competitive and recreational athletes. A crucial question is to which degree these variations are genuine or partly due to methodological incongruities. This paper discusses ...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,实务指引
doi：10.1177/2047487315599891
更新日期：2016-04-01 00:00:00
abstract：:Demographic changes, progress in medicine technology and regional problems in providing healthcare to low density populations are posing great challenges to our healthcare systems. Rapid progress in computer sciences and information technologies have a great impact on the way healthcare will be delivered in the near f...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章,评审
doi：10.1177/2047487316670256
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:Identification of individuals at risk for developing atrial fibrillation (AF) will help to target screening and preventive interventions. We aimed to validate the CHARGE-AF model (including variables age, race, height, weight, blood pressure, smoking, antihypertensive medication, diabetes, myocardial infarct...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/2047487314544045
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:Several selected population-based studies have emphasized the significance of resting heart rate as an independent cardiovascular risk factor. However, there are no data available for using resting heart rate as a cardiovascular risk predictor in contemporary primary care. Thus, the aim of our analysis was t...
journal_title：European journal of preventive cardiology
pub_type： 杂志文章
doi：10.1177/1741826710394304
更新日期：2012-04-01 00:00:00
