Abstract:
:Background Epidemiological studies on smoking and atrial fibrillation have been inconsistent, with some studies showing a positive association while others have found no association. It is also unclear whether there is a dose-response relationship between the number of cigarettes smoked or pack-years and the risk of atrial fibrillation. We conducted a systematic review and meta-analysis to clarify the association. Design Systematic review and meta-analysis. Methods We searched the PubMed and Embase databases for studies of smoking and atrial fibrillation up to 20 July 2017. Prospective studies and nested case-control studies within cohort studies reporting adjusted relative risk estimates and 95% confidence intervals (CIs) of atrial fibrillation associated with smoking were included. Summary relative risks (95% CIs) were estimated using a random effects model. Results Twenty nine prospective studies (22 publications) were included. The summary relative risk was 1.32 (95% CI 1.12-1.56, I2 = 84%, n = 11 studies) for current smokers, 1.09 (95% CI 1.00-1.18, I2 = 33%, n = 9) for former smokers and 1.21 (95% CI 1.12-1.31, I2 = 80%, n = 14) for ever smokers compared to never smokers. Comparing current versus non-current smokers the summary relative risk was 1.33 (95% CI 1.14-1.56, I2 = 78%, n = 10). The summary relative risk was 1.14 (95% CI 1.10-1.20, I2 = 0%, n = 3) per 10 cigarettes per day and 1.16 (95% CI 1.09-1.25, I2 = 49%, n = 2) per 10 pack-years and there was no evidence of a non-linear association for cigarettes per day, Pnon-linearity = 0.17. Conclusions The current meta-analysis suggests that smoking is associated with an increased risk of atrial fibrillation in a dose-dependent matter, but the association is weaker among former smokers compared to current smokers.
journal_name
Eur J Prev Cardioljournal_title
European journal of preventive cardiologyauthors
Aune D,Schlesinger S,Norat T,Riboli Edoi
10.1177/2047487318780435subject
Has Abstractpub_date
2018-09-01 00:00:00pages
1437-1451issue
13eissn
2047-4873issn
2047-4881journal_volume
25pub_type
杂志文章,meta分析abstract:BACKGROUND:Heart failure (HF) continues to be an illness of daunting proportions with a four- year mortality touching 50%. Biomarkers for prognosticating patients with heart failure have generated immense interest. Several studies have been conducted on a novel biomarker, galectin-3 to assess its prognostic effect in h...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,评审
doi:10.1177/2047487314552797
更新日期:2015-09-01 00:00:00
abstract:AIMS:Recent European guidelines recommend in patients with atherosclerotic cardiovascular disease to achieve a reduction of low-density lipoprotein-cholesterol of at least 50% if the baseline low-density lipoprotein-cholesterol level is between 1.8 and 3.5 mmol/L. Systematic reviews have associated a given statin/dose ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487319874898
更新日期:2020-10-01 00:00:00
abstract::Background This study examined the association between cardiac structure and function and the deterioration in activities of daily living (ADLs) in an age-homogenous, community-dwelling population of patients born in 1920-1921 over a five-year follow-up period. Design Longitudinal cohort study. Methods Patients were r...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487317744365
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The aim of this study was to test the hypothesis that alcohol consumption, both observational (self-reported) and estimated by genetic instruments, is associated with a risk of atrial fibrillation and to determine whether people with high cardiovascular risk are more sensitive towards alcohol than people wit...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究
doi:10.1177/2047487316641804
更新日期:2016-09-01 00:00:00
abstract::Background Preliminary evidence suggests that peak exercise oxygen pulse - peak oxygen uptake/heart rate-, a variable obtained during maximal cardiopulmonary exercise testing and a surrogate of stroke volume, is a predictor of mortality. We aimed to assess the associations of peak exercise oxygen pulse with sudden car...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487318761679
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:The incidence of metabolic syndrome (MetS), diabetes mellitus (DM), and their coexistence is increasing but whether MetS increases cardiovascular risk beyond component risk factors is controversial. DESIGN:We compared the risk of cardiovascular death, myocardial infarction, or stroke among patients with Met...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究
doi:10.1177/2047487313500541
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Lifestyle-based preventive cardiology aims to combat the global burden of cardiovascular disease. There have been rapid advances in lifestyle and behavioural interventions aimed at preventing cardiovascular disease in individuals at high risk and in the general population. This study is the first bibliometri...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487319854827
更新日期:2019-06-17 00:00:00
abstract::The use of preventive medications in people at high risk of cardiovascular disease is conceptually straightforward, yet in practice the adoption of such measures is disappointingly low, plus there is wide international variation in preventive therapies. Several barriers might explain this shortfall and variation, but ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/2047487312463278
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Cardiovascular diseases (CVD) and cancer are worldwide main causes of death with mortality trends varying across countries with different levels of economic development. DESIGN AND METHODS:We analysed trends in CVD and cancer mortality for 37 European countries, five high-income non-European countries and f...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487313497864
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Gonadal function is thought to be involved in existing atherosclerotic plaques stabilization and might affect reperfusion after primary percutaneous coronary intervention (pPCI). We aimed to compare the prevalence of hypotestosteromenia between ST-elevation myocardial infarction (STEMI) and stable angina (SA...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487314533084
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:There is strong evidence to suggest that social deprivation is linked to health inequalities. In the UK, concerns have been raised regarding disparities in the outcomes of acute cardiac services within the National Health Service (NHS). This study explored whether differences exist in (a) elective hospital p...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487314567000
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Statin intolerance is a barrier to effective lipid-lowering treatment. A significant number of patients stop prescribed statins, or can take only a reduced dose, because of adverse events attributed to the statin, and are then considered statin-intolerant. METHODS:Examination of differences between statin a...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,评审
doi:10.1177/2047487315602861
更新日期:2016-05-01 00:00:00
abstract::Numerous molecular screening strategies have recently been developed to measure the chemical diversity of a population's biofluids with the ultimate aim to provide clinicians, medical scientists and epidemiologists with a clearer picture of the presence and severity of cardiovascular disease; prognosis; and response t...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,评审
doi:10.1177/2047487316645469
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:International guidelines recommend pharmacotherapy combinations for chronic coronary syndromes (CCSs) but medical management remains suboptimal. DESIGN:The CICD-LT registry is investigating short- and long-term outcomes and management in patients in European Society of Cardiology (ESC) member countries, in ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487320912491
更新日期:2020-03-31 00:00:00
abstract::Background The risk of cardiovascular disease is closely connected to adipose tissue inflammation. The links between cardiovascular risk predictors and pro and anti-inflammatory macrophages in human adipose tissue were analysed to gain an insight into the pathophysiology of cardiovascular disease. Design Subcutaneous ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487317743355
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:We are unaware of any previous investigation that has compared the relationship of key cardiopulmonary exercise testing (CPX) variables to various measures of pathophysiology between heart failure-reduced ejection fraction (HFrEF) and HF-preserved ejection fraction (HFpEF) cohorts that are well matched with ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487313476962
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:While associations of smoking and preterm birth (PTB) with maternal cardiovascular disease (CVD) risks have been established, it is unknown whether the coexistence of these two conditions could synergistically increase the risks. METHODS:We linked birth records of 902,008 mothers with singleton infants duri...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487315593836
更新日期:2016-04-01 00:00:00
abstract::Background Physical fitness has been shown to predict cardiovascular death during long-term follow-up. In the present study we aimed to investigate how physical fitness and other cardiovascular risk factors at middle-age influenced the risk of cardiovascular death during the early (0-11 years), intermediate (12-23 yea...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487318793459
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Heart failure with preserved left ventricular ejection fraction (HFpEF) currently affects more than seven million Europeans and is the only cardiovascular disease increasing in prevalence and incidence. No pharmacological agent has yet been shown to improve symptoms or prognosis. The most promising way to im...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/2047487314552764
更新日期:2014-11-01 00:00:00
abstract::Aims Extracellular matrix remodelling may influence atherosclerotic progression and plaque stability. We hypothesized that evaluation of extracellular matrix markers, with potentially different roles during atherogenesis, could provide information on underlying mechanisms and risk of myocardial infarction (MI) in appa...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究
doi:10.1177/2047487317703826
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Exercise training is a non-pharmacological strategy for treatment of heart failure. Exercise training improves functional capacity and quality of life in patients. Moreover, exercise training reduces muscle sympathetic nerve activity (MSNA) and peripheral vasoconstriction. However, most of these studies have...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/1741826711414626
更新日期:2012-08-01 00:00:00
abstract::The United States Food and Drug Administration (FDA) has introduced manufacturing standards for dietary supplements, including red yeast rice, to assure their identity, purity, strength, and composition. One supplement commonly used to self-treat high cholesterol, red yeast rice, may contain monacolin K, an ingredient...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487317715714
更新日期:2017-09-01 00:00:00
abstract:AIMS:Due to improving cancer treatment results, non-cancer mortality is an important issue for cancer survivors. Cardiovascular diseases are the leading causes of death in Korea and globally. In addition to lowering the risk of cardiovascular disease, the use of statins has led to an overall reduction in cancer mortali...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487320905722
更新日期:2020-02-23 00:00:00
abstract:BACKGROUND:Obesity and physical inactivity in children correlate with the presence of cardiovascular risk factors. The aim of this prospective, randomised, interventional study was to examine the long term impact of additional physical exercise lessons at school on fitness and cardiovascular risk factors. METHODS:We r...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/2047487316632966
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:South Asians presenting with chest pain in the UK experience disproportionately greater delays with respect to diagnosis and treatment for acute myocardial infarction (AMI). The duration of time between symptom onset and hospital intervention is a critical delay for AMI but there are limited data amongst Sou...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487312447844
更新日期:2013-10-01 00:00:00
abstract::Aims HIV-infected persons may have elevated risks for heart failure, but factors associated with heart failure in the modern era of HIV therapy are insufficiently understood. Despite substantial disagreement between physician-adjudicated heart failure and heart failure diagnosis codes, few studies of HIV cohorts have ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487317732432
更新日期:2017-11-01 00:00:00
abstract::Background Although psychological interventions are recommended for the management of coronary heart disease (CHD), there remains considerable uncertainty regarding their effectiveness. Design Systematic review and meta-analysis of randomised controlled trials (RCTs) of psychological interventions for CHD. Methods The...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,meta分析
doi:10.1177/2047487317739978
更新日期:2018-02-01 00:00:00
abstract::Aims Haemodynamic parameters during and after exercise test seem to have a role in predicting cardiovascular events. We sought to evaluate the potential different responses in exercise capacity, heart rate and blood pressure levels in relation to major cardiovascular disease risk factors, among individuals undergoing ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487317726069
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Evaluation of health-related quality of life (HRQL) is important in improving the quality of patient care. The aim of this study was to determine the psychometric properties of the HeartQoL in patients with ischemic heart disease (IHD), specifically angina, myocardial infarction (MI), or ischemic heart failu...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究
doi:10.1177/2047487312450545
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Trials of weight-loss drugs indicate some benefits on lipids, blood glucose, or blood pressure levels. Since obesity is associated with increased cardiovascular (CV) medication use and pharmaceutical costs, weight-loss drug use could beneficially impact CV medication use. OBJECTIVE:We examined the temporal ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/1741826711406058
更新日期:2012-06-01 00:00:00