Clinical characteristics of HIV-infected patients with adjudicated heart failure.

Abstract:

:Aims HIV-infected persons may have elevated risks for heart failure, but factors associated with heart failure in the modern era of HIV therapy are insufficiently understood. Despite substantial disagreement between physician-adjudicated heart failure and heart failure diagnosis codes, few studies of HIV cohorts have evaluated adjudicated heart failure. We evaluated associations of HIV viremia, immunosuppression, and cardiovascular risk factors with physician-adjudicated heart failure. Methods and results We analyzed clinical characteristics associated with heart failure in a cohort of 5041 HIV-infected patients receiving care at an urban hospital system between 2000 and 2016. We also evaluated characteristics of HIV-infected patients who screened negative for heart failure, screened positive for possible heart failure but did not have heart failure after adjudication, and had adjudicated heart failure. HIV-infected patients with heart failure ( N = 216) were older and more likely to be black, hypertensive, and have diabetes than HIV-infected patients without heart failure; heart failure with reduced ejection fraction was more common than heart failure with preserved ejection fraction. In our primary analyses restricted to HIV-infected patients whose heart failure diagnoses did not precede their HIV diagnoses ( N = 149), peak HIV viral load ≥100,000 copies/mL (odds ratio (OR) 2.12, 1.28-3.52) and nadir CD4 T-cell count <200 cells/mm3 (OR 2.35, 1.04-5.31) were associated with significantly elevated odds of heart failure. Overall, 30.6% of patients with any diagnosis code of heart failure had adjudicated heart failure. Conclusion Higher peak HIV viremia and lower CD4 cell nadir are associated with significantly elevated odds of heart failure for HIV-infected persons. Physician adjudication of heart failure may be helpful in HIV cohorts.

journal_name

Eur J Prev Cardiol

authors

Steverson AB,Pawlowski AE,Schneider D,Nannapaneni P,Sanders JM,Achenbach CJ,Shah SJ,Lloyd-Jones DM,Feinstein MJ

doi

10.1177/2047487317732432

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

1746-1758

issue

16

eissn

2047-4873

issn

2047-4881

journal_volume

24

pub_type

杂志文章
  • Blood pressure variations and low blood pressure values at home after hospital discharge in older hypertensives: post-discharge blood pressure variations.

    abstract:BACKGROUND:Blood pressure (BP) variations occurring after hospital discharge in a population of older hypertensives have not been previously investigated. DESIGN:elderly (≥65 years) hypertensives admitted to the geriatric acute ward of a university-teaching hospital were enrolled in this prospective observational stud...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/1741826711403067

    authors: Astengo M,Bonetto M,Isaia G,Comba M,Fonte G,Bo M

    更新日期:2012-06-01 00:00:00

  • The HeartQoL: part II. Validation of a new core health-related quality of life questionnaire for patients with ischemic heart disease.

    abstract:BACKGROUND:Evaluation of health-related quality of life (HRQL) is important in improving the quality of patient care. The aim of this study was to determine the psychometric properties of the HeartQoL in patients with ischemic heart disease (IHD), specifically angina, myocardial infarction (MI), or ischemic heart failu...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/2047487312450545

    authors: Oldridge N,Höfer S,McGee H,Conroy R,Doyle F,Saner H,(for the HeartQoL Project Investigators).

    更新日期:2014-01-01 00:00:00

  • The benefits of exercise in cancer patients and the criteria for exercise prescription in cardio-oncology.

    abstract::Cancer and cardiovascular diseases are the leading causes of death in high-income countries. Cardiovascular complications can be found in cancer patients, being the result of so-called 'cardio-toxicity'. Therefore, it becomes essential to thoroughly investigate the origin of cardiac damage and the strategy to prevent ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319874900

    authors: D'Ascenzi F,Anselmi F,Fiorentini C,Mannucci R,Bonifazi M,Mondillo S

    更新日期:2019-10-06 00:00:00

  • Sudden cardiac arrest in sports - need for uniform registration: A Position Paper from the Sport Cardiology Section of the European Association for Cardiovascular Prevention and Rehabilitation.

    abstract::There are large variations in the incidence, registration methods and reported causes of sudden cardiac arrest/sudden cardiac death (SCA/SCD) in competitive and recreational athletes. A crucial question is to which degree these variations are genuine or partly due to methodological incongruities. This paper discusses ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,实务指引

    doi:10.1177/2047487315599891

    authors: Solberg EE,Borjesson M,Sharma S,Papadakis M,Wilhelm M,Drezner JA,Harmon KG,Alonso JM,Heidbuchel H,Dugmore D,Panhuyzen-Goedkoop NM,Mellwig KP,Carre F,Rasmusen H,Niebauer J,Behr ER,Thiene G,Sheppard MN,Basso C,Corrado

    更新日期:2016-04-01 00:00:00

  • Relative peak exercise oxygen pulse is related to sudden cardiac death, cardiovascular and all-cause mortality in middle-aged men.

    abstract::Background Preliminary evidence suggests that peak exercise oxygen pulse - peak oxygen uptake/heart rate-, a variable obtained during maximal cardiopulmonary exercise testing and a surrogate of stroke volume, is a predictor of mortality. We aimed to assess the associations of peak exercise oxygen pulse with sudden car...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487318761679

    authors: Laukkanen JA,Araújo CGS,Kurl S,Khan H,Jae SY,Guazzi M,Kunutsor SK

    更新日期:2018-05-01 00:00:00

  • Investigation of air pollution and noise on progression of thoracic aortic calcification: results of the Heinz Nixdorf Recall Study.

    abstract:AIMS:Air pollution and noise are potential risk factors for subclinical atherosclerosis. Longitudinal analyses, especially on the interplay of these environmental factors, are scarce and inconsistent. Hence we investigated long-term traffic-related exposure to air pollution and noise with the development and progressio...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319854818

    authors: Hennig F,Moebus S,Reinsch N,Budde T,Erbel R,Jöckel KH,Lehmann N,Hoffmann B,Kälsch H,Heinz Nixdorf Recall Study Investigative Group.

    更新日期:2020-06-01 00:00:00

  • Effect of the natural sweetener, steviol glycoside, on cardiovascular risk factors: a systematic review and meta-analysis of randomised clinical trials.

    abstract:INTRODUCTION:Many different dietary supplements are currently marketed for the management of hypertension and diabetes, but the evidence for effectiveness is mixed. The objective of this systematic review was to critically appraise and evaluate the evidence for effectiveness of steviol glycosides (stevioside and rebaud...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1177/2047487314560663

    authors: Onakpoya IJ,Heneghan CJ

    更新日期:2015-12-01 00:00:00

  • Long-term prescription of beta-blocker delays the progression of heart failure with preserved ejection fraction in patients with hypertension: A retrospective observational cohort study.

    abstract:BACKGROUND:Hypertension complicated with left ventricular hypertrophy (LVH) and diastolic dysfunction is one of the most common risks for heart failure with preserved ejection fraction (HFpEF). This study was designed to evaluate the influences of long-term beta-blocker prescription in these patients. METHODS:This ret...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487316636260

    authors: Gu J,Fan YQ,Bian L,Zhang HL,Xu ZJ,Zhang Y,Chen QZ,Yin ZF,Xie YS,Wang CQ

    更新日期:2016-09-01 00:00:00

  • Adiponectin, type 2 diabetes and cardiovascular risk.

    abstract:BACKGROUND:Adiponectin is viewed as an insulin-sensitizing hormone with anti-inflammatory effects. In accordance, plasma adiponectin is decreased in metabolic disorders including type 2 diabetes mellitus (T2DM). However, in spite of the apparently beneficially effects, recent data from large prospective studies have co...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487313514894

    authors: Lindberg S,Jensen JS,Bjerre M,Pedersen SH,Frystyk J,Flyvbjerg A,Galatius S,Jeppesen J,Mogelvang R

    更新日期:2015-03-01 00:00:00

  • Ability to sit and rise from the floor as a predictor of all-cause mortality.

    abstract:BACKGROUND:While cardiorespiratory fitness is strongly related to survival, there are limited data regarding musculoskeletal fitness indicators. Our aim was to evaluate the association between the ability to sit and rise from the floor and all-cause mortality. DESIGN:Retrospective cohort. METHODS:2002 adults aged 51-...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487312471759

    authors: Brito LB,Ricardo DR,Araújo DS,Ramos PS,Myers J,Araújo CG

    更新日期:2014-07-01 00:00:00

  • Of heart and kidney: a complicated love story.

    abstract::The multiple connections that exist between the cardiovascular system and the kidney lead to a complex cardiovascular and renal medicine relationship. It is well established in the literature that chronic kidney disease (CKD) is an important and independent risk factor for cardiovascular disease (CVD). The prevalence ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,评审

    doi:10.1177/2047487312462826

    authors: Gaita D,Mihaescu A,Schiller A

    更新日期:2014-07-01 00:00:00

  • Efficacy and safety of statins and exercise combination therapy compared to statin monotherapy in patients with dyslipidaemia: A systematic review and meta-analysis.

    abstract::Background Statin treatment in association with physical exercise can substantially reduce mortality in dyslipidaemic individuals. However, the available data to compare the efficacy and safety of statins and exercise combination therapy with statin monotherapy are limited. Design Systematic review and meta-analysis. ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1177/2047487317691874

    authors: Gui YJ,Liao CX,Liu Q,Guo Y,Yang T,Chen JY,Wang YT,Hu JH,Xu DY

    更新日期:2017-06-01 00:00:00

  • Serum tissue-degrading proteinases and incident cardiovascular disease events.

    abstract:BACKGROUND:Extracellular matrix-degrading proteinases are upregulated in atherosclerotic lesions and can contribute to subsequent pathological events. In the present nested case-control study, we investigated the association of serum concentrations of matrix metalloproteinases MMP-7, MMP-8, and MMP-13, tissue inhibitor...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487312465524

    authors: Tuomainen AM,Kormi I,Havulinna AS,Tervahartiala T,Salomaa V,Sorsa T,Pussinen PJ

    更新日期:2014-07-01 00:00:00

  • Lifestyle factors and high-risk atherosclerosis: Pathways and mechanisms beyond traditional risk factors.

    abstract::Despite major efforts to reduce atherosclerotic cardiovascular disease (ASCVD) burden with conventional risk factor control, significant residual risk remains. Recent evidence on non-traditional determinants of cardiometabolic health has advanced our understanding of lifestyle-disease interactions. Chronic exposure to...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,评审

    doi:10.1177/2047487319869400

    authors: Lechner K,von Schacky C,McKenzie AL,Worm N,Nixdorff U,Lechner B,Kränkel N,Halle M,Krauss RM,Scherr J

    更新日期:2020-03-01 00:00:00

  • Completion and adherence rates to exercise interventions in intermittent claudication: Traditional exercise versus alternative exercise - a systematic review.

    abstract:BACKGROUND:Intermittent claudication, defined as fatigue or pain in the legs while walking, is a common symptom in peripheral arterial disease. Although exercise effectively improves function and manages symptoms, adherence rates are not ideal. The high levels of pain experienced in traditional exercise programmes may ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319846997

    authors: Lin E,Nguyen CH,Thomas SG

    更新日期:2019-10-01 00:00:00

  • Abdominal obesity and the risk of recurrent atherosclerotic cardiovascular disease after myocardial infarction.

    abstract:BACKGROUND:The association between abdominal obesity and recurrent atherosclerotic cardiovascular disease after myocardial infarction remains unknown. OBJECTIVE:The purpose of this study was to investigate the prevalence of abdominal obesity and its association with recurrent atherosclerotic cardiovascular disease in ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319898019

    authors: Mohammadi H,Ohm J,Discacciati A,Sundstrom J,Hambraeus K,Jernberg T,Svensson P

    更新日期:2020-12-01 00:00:00

  • Trends in socioeconomic inequalities in mortality from ischaemic heart disease and stroke in Australia, 1979-2006.

    abstract:BACKGROUND:This study investigates secular trends in ischaemic heart disease (IHD) and stroke mortality by socioeconomic status (SES) in Australia to determine if absolute and relative differences between low and high SES areas have changed over time. METHODS:IHD and stroke mortality data for adults aged 35-74 years a...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/1741826711427505

    authors: Page A,Lane A,Taylor R,Dobson A

    更新日期:2012-12-01 00:00:00

  • Compositional analysis of the association between mortality and 24-hour movement behaviour from NHANES.

    abstract:AIMS:Previous prospective studies of the association between mortality and physical activity have generally not fully accounted for the interplay between movement behaviours. A compositional data modelling approach accounts for relative scale and co-dependency in time-use data across physical activity behaviours of the...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319867783

    authors: McGregor DE,Palarea-Albaladejo J,Dall PM,Del Pozo Cruz B,Chastin SF

    更新日期:2019-08-05 00:00:00

  • Hypotestosteronemia is frequent in ST-elevation myocardial infarction patients and is associated with coronary microvascular obstruction.

    abstract:BACKGROUND:Gonadal function is thought to be involved in existing atherosclerotic plaques stabilization and might affect reperfusion after primary percutaneous coronary intervention (pPCI). We aimed to compare the prevalence of hypotestosteromenia between ST-elevation myocardial infarction (STEMI) and stable angina (SA...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487314533084

    authors: Niccoli G,Milardi D,D'Amario D,Fracassi F,Grande G,Panico RA,Roberto M,Mirizzi AM,Canu G,De Marinis L,Carrozza C,Pontecorvi A,Crea F

    更新日期:2015-07-01 00:00:00

  • Health-related quality of life and risk of composite coronary heart disease and cerebrovascular events in the Moli-sani study cohort.

    abstract::Background To assess the association between health-related quality of life (HRQL) and a composite outcome including incident coronary heart disease (CHD) and cerebrovascular events in a large general population-based cohort. Design Prospective analysis on 17,102 men and women (mean age 53 ± 11) free from cardiovascul...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487317748452

    authors: Bonaccio M,Di Castelnuovo A,Costanzo S,Persichillo M,De Curtis A,Cerletti C,Donati MB,de Gaetano G,Iacoviello L,Moli-sani Study Investigators.

    更新日期:2018-02-01 00:00:00

  • Management of patients with type 2 diabetes in cardiovascular rehabilitation.

    abstract::The clinical benefits of rehabilitation in cardiovascular disease are well established. Among cardiovascular disease patients, however, patients with type 2 diabetes mellitus require a distinct approach. Specific challenges to clinicians and healthcare professionals in patients with type 2 diabetes include the prevale...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,评审

    doi:10.1177/2047487319882820

    authors: Hansen D,Kraenkel N,Kemps H,Wilhelm M,Abreu A,Pfeiffer AF,Jordão A,Cornelissen V,Völler H

    更新日期:2019-12-01 00:00:00

  • Risk factor levels, risk factor combinations, and residual coronary risk: population-based estimates for secondary prevention patients using statins.

    abstract:BACKGROUND:Population-based risk factor combinations and residual risks for coronary heart disease (CHD) patients on statins were assessed in order to bridge the gap between knowledge on relative effects from clinical trials and absolute risk from real-world practice. DESIGN:Population-based, retrospective 1-year cros...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/1741826710392668

    authors: Krobot KJ,Wagner A,Siebert U

    更新日期:2012-02-01 00:00:00

  • Cardiovascular disease and risk factors in an indigenous minority population. The All-Ireland Traveller Health Study.

    abstract:BACKGROUND:The Traveller community are an indigenous minority group in Great Britain and Ireland who experience premature mortality. While minority populations worldwide are known to have high rates of risk factors for cardiovascular disease (CVD), Traveller CVD risk has not previously been defined. DESIGN:All-Ireland...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/1741826711428059

    authors: McGorrian C,Daly L,Fitzpatrick P,Moore RG,Turner J,Kelleher CC,All-Ireland Traveller Health Study Team.

    更新日期:2012-12-01 00:00:00

  • Cardiorespiratory fitness and survival following cancer diagnosis.

    abstract:AIMS:Data on the association of cardiorespiratory fitness with survival of cancer patients are limited. This study aimed to evaluate the association between midlife cardiorespiratory fitness and survival after a subsequent cancer diagnosis. METHODS:We evaluated 19,134 asymptomatic self-referred adults who were screene...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487320930873

    authors: Fardman A,Banschick GD,Rabia R,Percik R,Fourey D,Segev S,Klempfner R,Grossman E,Maor E

    更新日期:2020-07-19 00:00:00

  • Sacubitril-valsartan versus enalapril for acute decompensated heart failure: a cost-effectiveness analysis.

    abstract:BACKGROUND:The Comparison of Sacubitril-Valsartan versus Enalapril on Effect on NT-proBNP in Patients Stabilised from an Acute Heart Failure Episode (PIONEER-HF) trial demonstrated significant reductions in N-terminal pro-B-type natriuretic peptide. Our study explored the cost-effectiveness of the use of sacubitril-val...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319878953

    authors: Perera K,Ademi Z,Liew D,Zomer E

    更新日期:2019-10-04 00:00:00

  • Treat-to-target versus dose-adapted statin treatment of cholesterol to reduce cardiovascular risk.

    abstract::Clinical guidelines should be based on the best available evidence and are of great importance for patient care and disease prevention. In this respect, the 2013 American College of Cardiology/American Heart Association report is highly appreciated and well-recognized. The report included critical questions concerning...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487314567001

    authors: Müller-Wieland D,Assmann G,Carmena R,Davignon J,von Eckardstein A,Farinaro E,Greten H,Olsson AG,Riesen WF,Shlyakhto E

    更新日期:2016-02-01 00:00:00

  • Opportunistic screening models for high-risk men and women to detect diastolic dysfunction and heart failure with preserved ejection fraction in the community.

    abstract:BACKGROUND:The prevalence of undetected left ventricular diastolic dysfunction is high, especially in the elderly with comorbidities. Left ventricular diastolic dysfunction is a prognostic indicator of heart failure, in particularly of heart failure with preserved ejection fraction and of future cardiovascular and all-...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487318816774

    authors: Gohar A,Kievit RF,Valstar GB,Hoes AW,Van Riet EE,van Mourik Y,Bertens LC,Boonman-Winter LJ,Bots ML,Den Ruijter HM,Rutten FH

    更新日期:2019-04-01 00:00:00

  • Extracellular vesicle species differentially affect endothelial cell functions and differentially respond to exercise training in patients with chronic coronary syndromes.

    abstract:BACKGROUND:Extracellular vesicles are released upon cellular activation and mediate inter-cellular communication. Individual species of extracellular vesicles might have divergent roles in vascular homeostasis and may show different responses to therapies such as exercise training. AIMS:We examine endothelial effects ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487320919894

    authors: Kränkel N,Strässler E,Uhlemann M,Müller M,Briand-Schumacher S,Klingenberg R,Schulze PC,Adams V,Schuler G,Lüscher TF,Möbius-Winkler S,Landmesser U

    更新日期:2020-05-07 00:00:00

  • The case for extended thromboprophylaxis in medically hospitalised patients - not yet made.

    abstract:BACKGROUND:The role of extended thromboprophylaxis is established for surgical patients, but not yet for hospitalised medical patients. DESIGN:This systematic review and meta-analysis sought to explore the role of extended thromboprophylaxis for medically ill hospitalised patients. METHODS:Medline, EMBASE and Cochran...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319836572

    authors: Cao JY,Lee SY,Dunkley S,Adams M,Keech A

    更新日期:2019-03-16 00:00:00

  • Predictive and explanatory factors of cardiovascular disease in people with adequately controlled type 2 diabetes.

    abstract::Aims To explore the predictive and explanatory factors on the incidence of cardiovascular disease and the impact of visit-to-visit variability (VVV) of risk factors on incident cardiovascular disease in people with type 2 diabetes with no history of prior cardiovascular disease. Methods We performed a historical cohor...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487317707293

    authors: Hashemi Madani N,Ismail-Beigi F,Khamseh ME,Malek M,Ebrahimi Valojerdi A

    更新日期:2017-07-01 00:00:00