Abstract:
BACKGROUND:Several selected population-based studies have emphasized the significance of resting heart rate as an independent cardiovascular risk factor. However, there are no data available for using resting heart rate as a cardiovascular risk predictor in contemporary primary care. Thus, the aim of our analysis was to examine the clinical value of the measurement of resting heart rate in a large, unselected population-based cohort of primary care subjects under the conditions of contemporary primary prevention. DESIGN:Prospective, population-based cohort study. METHODS:We examined a subgroup of 5320 unselected primary care subjects free of coronary artery disease from the nationwide, longitudinal Diabetes Cardiovascular Risk Evaluation Targets and Essential Data for Commitment of Treatment (DETECT) cohort study, which was conducted from 2003 to 2008. RESULTS:During the follow-up time of 5 years, 258 events were reported. Elevated resting heart rate was not associated with an increased risk for cardiovascular events (HR = 0.75, p = 0.394), cardiovascular mortality (HR = 0.71, p = 0.616) or major cardiovascular events (HR = 0.77, p = 0.376). By cross-sectional analysis, elevated heart rate clustered with markers of the metabolic syndrome, like increased blood pressure (systolic: OR = 5.54, p < 0.0001; diastolic: OR = 3.82, p < 0.0001), elevated fasting plasma glucose levels (OR = 8.84, p < 0.0001), hypertriglyceridaemia (OR = 22.16, p = 0.001), and obesity (body mass index OR = 0.89, p < 0.0001). Assessment of resting heart rate in clinical practice had minimal and non-significant additional prognostic value compared to established cardiovascular risk factors as judged by C statistics (C = 0.001, p = 0.979). CONCLUSION:The measurement of resting heart rate in the daily routine of primary care does not provide incremental prognostic information for cardiovascular risk stratification.
journal_name
Eur J Prev Cardioljournal_title
European journal of preventive cardiologyauthors
Leistner DM,Klotsche J,Palm S,Pieper L,Stalla GK,Lehnert H,Silber S,März W,Wittchen HU,Zeiher AM,DETECT-Study Group.doi
10.1177/1741826710394304subject
Has Abstractpub_date
2012-04-01 00:00:00pages
275-84issue
2eissn
2047-4873issn
2047-4881pii
1741826710394304journal_volume
19pub_type
杂志文章abstract::Aims To evaluate safety and efficacy of moderate intensity interval exercise training early after heart failure decompensation on exercise tolerance and health-related quality of life (HRQoL). Methods and results This is a prospective randomized controlled study. We screened 234 consecutive patients admitted with deco...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1177/2047487317724575
更新日期:2018-01-01 00:00:00
abstract:AIMS:European Society of Cardiology/European Atherosclerosis Society 2019 guidelines recommend more aggressive lipid targets in high- and very high-risk patients and the addition of adjuvant treatments to statins in uncontrolled patients. We aimed to assess (a) achievement of prior and new European Society of Cardiolog...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487320914115
更新日期:2020-03-31 00:00:00
abstract:BACKGROUND:Patients with heart failure with preserved ejection fraction (HFpEF) are often elderly and their primary chronic symptom is severe exercise intolerance that results in a reduced quality of life (QOL).Thus, improvement of exercise capacity and QOL presents an important clinical outcome in HFpEF patients. Alth...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,meta分析
doi:10.1177/2047487314564729
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:The purpose of this investigation was to identify a quantitative dose-response relationship for enhancing maximal oxygen consumption (VO2max) in healthy sedentary older adults after controlled endurance training. METHODS AND RESULTS:This meta-analysis of controlled clinical trials included 1257 exercisers a...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,meta分析
doi:10.1177/2047487315582322
更新日期:2016-03-01 00:00:00
abstract::Background Epidemiological studies on smoking and atrial fibrillation have been inconsistent, with some studies showing a positive association while others have found no association. It is also unclear whether there is a dose-response relationship between the number of cigarettes smoked or pack-years and the risk of a...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,meta分析
doi:10.1177/2047487318780435
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Quadriceps strength is related to exercise capacity in normal subjects and different patient populations, but the relationship between maximal quadriceps isometric strength (QIS) and different exercise capacity levels in coronary artery disease (CAD) patients has not been systematically evaluated yet. METHO...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487313492252
更新日期:2014-10-01 00:00:00
abstract:AIMS:Data on the association of cardiorespiratory fitness with survival of cancer patients are limited. This study aimed to evaluate the association between midlife cardiorespiratory fitness and survival after a subsequent cancer diagnosis. METHODS:We evaluated 19,134 asymptomatic self-referred adults who were screene...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487320930873
更新日期:2020-07-19 00:00:00
abstract::Demographic changes, progress in medicine technology and regional problems in providing healthcare to low density populations are posing great challenges to our healthcare systems. Rapid progress in computer sciences and information technologies have a great impact on the way healthcare will be delivered in the near f...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,评审
doi:10.1177/2047487316670256
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:The exercise electrocardiographic stress test (ExET) is the most widely used non-invasive diagnostic method to detect coronary artery disease. However, the sole ST depression criteria (ST-max) have poor specificity for coronary artery disease in patients with left ventricular hypertrophy. We hypothesised tha...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究
doi:10.1177/2047487316655259
更新日期:2016-10-01 00:00:00
abstract::Heart failure (HF) is one of the major challenges in the management of diabetes patients. Among subjects with diabetes, up to 20% could have HF. Conversely, diabetes prevalence in HF patients varies greatly from more than 10% up to 50%. When it is present, the risk of mortality and rehospitalization increases substant...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,评审
doi:10.1177/2047487319885461
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:In order to improve national cardiovascular disease (CVD) epidemiology and prevention, we systematically reviewed and analyzed the relevant literature produced in the last three decades for Spain. DESIGN:Systematic Review. METHODS:We searched for all the articles aiming to monitor CVD clinical endpoints an...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,评审
doi:10.1177/2047487312455314
更新日期:2013-08-01 00:00:00
abstract::Using data from the Seven Countries Study of Cardiovascular Diseases, the first study to conduct international comparisons of men in different European, USA, and Japanese cohorts, we examined the effect of diet-associated inflammation on prediction of coronary heart disease-, other major cardiovascular disease- and al...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487320903866
更新日期:2020-02-04 00:00:00
abstract::Background Cardiac rehabilitation (CR) improves the symptoms, exercise capacity and quality of life of chronic heart failure (CHF) patients. Its effects on new plasma biomarkers of prognostic importance are unknown. The present study aimed at analysing the effects of a structured CR programme on plasma cardiac biomark...
journal_title:European journal of preventive cardiology
pub_type: 临床试验,杂志文章
doi:10.1177/2047487317705488
更新日期:2017-07-01 00:00:00
abstract::Aims HIV-infected persons may have elevated risks for heart failure, but factors associated with heart failure in the modern era of HIV therapy are insufficiently understood. Despite substantial disagreement between physician-adjudicated heart failure and heart failure diagnosis codes, few studies of HIV cohorts have ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487317732432
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:The test-retest reliability for multiple cardiopulmonary exercise test (CPX) variables has not been compared in a single study and the influence of different diseases on test-retest reliability has not been examined. We investigated different measures of test-retest reliability for multiple variables and com...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487313518474
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Blood pressure (BP) variations occurring after hospital discharge in a population of older hypertensives have not been previously investigated. DESIGN:elderly (≥65 years) hypertensives admitted to the geriatric acute ward of a university-teaching hospital were enrolled in this prospective observational stud...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/1741826711403067
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:The aim of the study was to investigate the effects of sesame oil on endothelial function and to detect the underlying mechanisms, both in the postprandial state and after long-term consumption. DESIGN:We enrolled 30 hypertensive men in a two-phase study. In the first phase, 26 volunteers consumed 35 g of e...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487312437625
更新日期:2013-04-01 00:00:00
abstract::Background Chronic Rheumatic Heart disease (RHD) continues to be a health problem in many low and middle income countries and especially in sub-Saharan Africa. Echocardiography has shown that the disease is far more widespread than may be detected by clinical assessment, but data are lacking on the prevalence and epid...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487316687104
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:In western populations, high-sensitivity C-reactive protein (hsCRP), and to a lesser degree serum creatinine and haemoglobin A1c, predict risk of coronary heart disease (CHD). However, data on Asian populations that are increasingly affected by CHD are sparse and it is not clear whether these biomarkers can ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究
doi:10.1177/2047487315626547
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Few data have assessed the incidence, site and predictors of infections following cardiac surgery after discharge, particularly during an early rehabilitation phase. AIM:To assess the epidemiology and predictors of infections occurring after cardiac surgery. METHODS:Data prospectively recorded from 5464 pa...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487315576129
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:In clinical practice, individuals at increased risk of cardiovascular diseases (CVD) are identified on the basis of age, sex, smoking, blood pressure, and serum total and high-density lipoprotein cholesterol. We examined whether CVD risk prediction improved when obesity (body mass index ≥30 kg/m(2)) and prem...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487312444233
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:The association between abdominal obesity and recurrent atherosclerotic cardiovascular disease after myocardial infarction remains unknown. OBJECTIVE:The purpose of this study was to investigate the prevalence of abdominal obesity and its association with recurrent atherosclerotic cardiovascular disease in ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487319898019
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Heart failure (HF) continues to be an illness of daunting proportions with a four- year mortality touching 50%. Biomarkers for prognosticating patients with heart failure have generated immense interest. Several studies have been conducted on a novel biomarker, galectin-3 to assess its prognostic effect in h...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,评审
doi:10.1177/2047487314552797
更新日期:2015-09-01 00:00:00
abstract:AIMS:The European Cardiac Rehabilitation in the Elderly (EU-CaRE) HORIZON 2020 project compares the sustainable effects of cardiac rehabilitation (CR) in elderly patients. METHODS AND RESULTS:A total of 1633 patients with coronary artery disease (CAD) or heart valve replacement (HVR), with or without revascularization...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487320903869
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Cardiac rehabilitation programmes are strongly recommended for all forms of coronary artery disease to reduce recurrent events and mortality. Few patients seem to participate in these programmes after elective percutaneous coronary intervention (PCI). The aim of this study was to assess changes in lifestyle ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487312447751
更新日期:2013-10-01 00:00:00
abstract:AIMS:Reviews of clinical practice guidelines have repeatedly concluded that only a minority of guideline recommendations are supported by high-quality evidence from randomised controlled trials. The aim of this study is to evaluate whether these findings apply to the whole cardiovascular evidence base or specific recom...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487319868540
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Cardiac rehabilitation (CR) is an evidence-based recommendation for patients with coronary artery disease (CAD). However, CR is dramatically underutilized. Telehealth interventions have the potential to overcome barriers and may be an innovative model of delivering CR. This review aimed to determine the effe...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1177/2047487314561168
更新日期:2015-08-01 00:00:00
abstract::The multiple connections that exist between the cardiovascular system and the kidney lead to a complex cardiovascular and renal medicine relationship. It is well established in the literature that chronic kidney disease (CKD) is an important and independent risk factor for cardiovascular disease (CVD). The prevalence ...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,评审
doi:10.1177/2047487312462826
更新日期:2014-07-01 00:00:00
abstract::Background Cardiovascular disease (CVD) prevention is commonly focused on providing individuals at high predicted CVD risk with preventive medication. Whereas CVD risk increases rapidly with age, current risk-based selection of individuals mainly targets the elderly. However, the lifelong (preventable) consequences of...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究
doi:10.1177/2047487317752948
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Cardiovascular risk factors tend to be clustered. Variations in clusters across populations have not been widely investigated. This study aims to compare the prevalence and clustering of major cardiovascular risk factors between adults in the Netherlands and China. METHODS:A total of 6542 Dutch adults was r...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究
doi:10.1177/2047487316648474
更新日期:2016-11-01 00:00:00