Abstract:
AIMS:The European Cardiac Rehabilitation in the Elderly (EU-CaRE) HORIZON 2020 project compares the sustainable effects of cardiac rehabilitation (CR) in elderly patients. METHODS AND RESULTS:A total of 1633 patients with coronary artery disease (CAD) or heart valve replacement (HVR), with or without revascularization, aged 65 or above, who participated in CR were included. Peak oxygen uptake (VO2peak), smoking, body mass index, diet, physical activity, serum lipids, psychological distress and medication were assessed before and after CR (T0 and T1) and after 12 months (T2). Patients undergoing coronary artery bypass surgery or surgical HVR had lower VO2peak at T0 and a greater increase to T1 and T2 (2.8 and 4.4 ml/kg/min, respectively) than CAD patients undergoing percutaneous or no revascularization (1.6 and 1.4 ml/kg/min, respectively). After multivariable adjustment, earlier CR uptake was associated with greater improvements in VO2peak. The proportion of CAD patients with three or more uncontrolled risk factors declined from 58.4% at T0 to 40.1% at T2 (p < 0.0001). Psychological distress scores all improved and adherence to medication was overall good at all sites. There were significant differences in risk factor burden across sites, but no CR program was superior to others. CONCLUSIONS:The outcomes of VO2peak in CR programs across Europe seemed mainly determined by timing of uptake and were maintained or even further improved at 1-year follow-up. Despite significant improvements, 40.1% of CAD patients still had three or more risk factors not at target after 1 year. Differences across sites could not be ascribed to characteristics of the CR programs offered.
journal_name
Eur J Prev Cardioljournal_title
European journal of preventive cardiologyauthors
Prescott E,Eser P,Mikkelsen N,Holdgaard A,Marcin T,Wilhelm M,Gil CP,González-Juanatey JR,Moatemri F,Iliou MC,Schneider S,Schromm E,Zeymer U,Meindersma EP,Crocamo A,Ardissino D,Kolkman EK,Prins LF,van der Velde AE,Vadoi
10.1177/2047487320903869subject
Has Abstractpub_date
2020-11-01 00:00:00pages
1716-1729issue
16eissn
2047-4873issn
2047-4881journal_volume
27pub_type
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journal_title:European journal of preventive cardiology
pub_type: 杂志文章
doi:10.1177/2047487312471759
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journal_title:European journal of preventive cardiology
pub_type: 杂志文章,实务指引
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,多中心研究,随机对照试验
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