Abstract:
BACKGROUND:The test-retest reliability for multiple cardiopulmonary exercise test (CPX) variables has not been compared in a single study and the influence of different diseases on test-retest reliability has not been examined. We investigated different measures of test-retest reliability for multiple variables and compared them by category of cardiac or respiratory disease. METHODS:Patients with chronic obstructive airways disease (n = 24), heart failure (n = 43), or severe mitral valve disease (n = 26) were recruited into a prospective study. Each patient underwent two bicycle ergometer tests; the first, a familiarization test, with a 10 W/min ramp, and the second a personalized ramp based on the results of the familiarization test to elicit maximal effort within 8-10 min. Intraclass correlation coefficients (ICC) and coefficients of variation between the two tests were calculated. Influence of potential modifiers was assessed using repeated measures analysis of variance. RESULTS:Peak VO2 (ICC 0.95, 95% CI 0.94-0.97), oxygen uptake efficiency slope (ICC 0.93, 95% CI 0.90-0.95), O2 pulse (ICC 0.96, 95% CI 0.94-0.97), and the VE/VCO2 ratio at the nadir (ICC 0.92, 95% CI 0.89-0.95) all showed excellent test-retest reliability, with within-subject coefficients of variation <0.12. VO2 at the anaerobic threshold (ICC 0.84, 95% CI 0.78-0.89) and the VE/VCO2 slope (ICC 0.88, 95% CI 0.79-0.93) showed good test-retest reliability, although inferior to peak VO2. Age, gender, body mass index, disease aetiology, protocol change, and intertest interval did not affect the reliability of most variables. CONCLUSIONS:CPX showed high test-retest reliability; certain variables such as peak VO2 and oxygen uptake efficiency slope outperform others. These results identify which variables are most suitable for serial testing of patients with three common disease aetiologies owing to their superior reproducibility.
journal_name
Eur J Prev Cardioljournal_title
European journal of preventive cardiologyauthors
Barron A,Dhutia N,Mayet J,Hughes AD,Francis DP,Wensel Rdoi
10.1177/2047487313518474subject
Has Abstractpub_date
2014-04-01 00:00:00pages
445-53issue
4eissn
2047-4873issn
2047-4881pii
2047487313518474journal_volume
21pub_type
杂志文章abstract:BACKGROUND:Cardiovascular risk factors are known to be associated between parents and offspring. However, whether these associations are reflected in increased offspring mortality has not been extensively studied. DESIGN:This was a family study of 32,536 father-offspring and 39,614 mother-offspring pairs who participa...
journal_title:European journal of preventive cardiology
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pub_type: 杂志文章,多中心研究
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journal_title:European journal of preventive cardiology
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journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:European journal of preventive cardiology
pub_type: 杂志文章,随机对照试验
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journal_title:European journal of preventive cardiology
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journal_title:European journal of preventive cardiology
pub_type: 杂志文章,评审
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更新日期:2018-02-01 00:00:00
abstract::Background The general belief is that caffeine increases the risk of hyperkinetic arrhythmias, including atrial fibrillation. The aim of this study is to investigate the effect of chronic caffeine intake on incident atrial fibrillation in general population. Design and methods A population cohort of 1475 unselected me...
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更新日期:2018-07-01 00:00:00
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更新日期:2015-12-01 00:00:00
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journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/2047487312449593
更新日期:2013-12-01 00:00:00
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abstract::The clinical benefits of rehabilitation in cardiovascular disease are well established. Among cardiovascular disease patients, however, patients with type 2 diabetes mellitus require a distinct approach. Specific challenges to clinicians and healthcare professionals in patients with type 2 diabetes include the prevale...
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pub_type: 杂志文章,多中心研究
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更新日期:2014-12-01 00:00:00
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pub_type: 杂志文章,实务指引
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更新日期:2013-06-01 00:00:00
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更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Prospective relationships between sedentary behaviour and cardiorespiratory and metabolic markers need to be better delineated in adults with different physical activity levels. We examined the separate and combined relationships of work and leisure time sitting and moderate to vigorous physical activity (MV...
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pub_type: 杂志文章,多中心研究
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更新日期:2016-08-01 00:00:00
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更新日期:2013-02-01 00:00:00
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pub_type: 杂志文章,多中心研究
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