Excessive glucocorticoid-induced muscle MuRF1 overexpression is independent of Akt/FoXO1 pathway.

abstract：:The effect of sodium butyrate (NaBut) on cell growth was studied in normal rat kidney (NRK) fibroblasts, and in NRK cells stably transfected with either the adenoviral gene E1A (wild-type), or mutated E1A (E1Amut; with a deletion in the CR1 domain), or with the transforming Ha-ras (EJ) gene. The growth of all these ce...

journal_title：Bioscience reports

authors： Joensuu T,Mester J

更新日期：1994-12-01 00:00:00

abstract：:Whether serum copper levels were higher in patients with cervical cancer than that in controls was controversial. Hence, we conducted the present study to explore the relationship between serum copper levels and cervical cancer. We searched PubMed, WanFang, and China National Knowledge Internet (CNKI) for relevant stu...

journal_title：Bioscience reports

authors： Zhang M,Shi M,Zhao Y

更新日期：2018-07-06 00:00:00

abstract：:MicroRNAs (miRNAs) have been frequently identified as key mediators in almost all developmental and pathological processes, including those in the liver. The present study was conducted with aims of investigating the role of microRNA-138 (miR-138) in acute liver failure (ALF) via a mechanism involving p53 and liver ma...

journal_title：Bioscience reports

authors： Wang YQ,Lan YY,Guo YC,Yuan QW,Liu P

更新日期：2019-07-18 00:00:00

abstract：:The growth arrest special 5 (GAS5), as a research hotspot of long noncoding RNAs (lncRNAs), has been reported to be associated with colorectal cancer (CRC). However, the association between polymorphisms in GAS5 and the risk of CRC was not clear. In the present study, a case-control study in 1078 CRC patients and 1175...

journal_title：Bioscience reports

authors： Wang Y,Wu S,Yang X,Li X,Chen R

更新日期：2019-04-16 00:00:00

abstract：:Endothelin-1 (ET-1) and plasminogen activator inhibitor-1 (PAI-1) play important roles in pulmonary hypertension (PH) in sickle cell disease (SCD). Our previous studies show higher levels of placenta growth factor (PlGF) in SCD correlate with increased plasma levels of ET-1, PAI-1, and other physiological markers of P...

journal_title：Bioscience reports

authors： Gonsalves CS,Li C,Malik P,Tahara SM,Kalra VK

更新日期：2015-10-12 00:00:00

abstract：:In order to better understand the role of cell surface glycolipids in T lymphocyte activation, heparin was used to simultaneously modulate the expression of glycolipids and the lytic capacity of lymphocytes activated by interleukin-2. Results presented here show that heparin added at the start of a 3 day culture inhib...

journal_title：Bioscience reports

authors： Schwarting GA,Gajewski A

更新日期：1988-08-01 00:00:00

abstract：:Erectile dysfunction (ED) is one of the significant complications of diabetes mellitus (DM), and CASR plays an important role in cellular antiapoptosis and NO production in the vascular endothelium by activating PKC. The present study was aimed to investigate the efficacy of Leech and Centipede Granules (LCG) through ...

journal_title：Bioscience reports

authors： Ma JX,Wang B,Ding CF,Li HS,Jiang XJ,Wang CY,Yu J,Chen WQ

更新日期：2020-02-28 00:00:00

abstract：:31P NMR studies on microorganisms have been carried out with the cells embedded in agarose gel. The novel use of the gel for the NMR studies has advantages over the usual liquid suspensions in terms of improved reproducibility of data and cell viability, with no net loss of spectral quality. Polyphosphate formation in...

journal_title：Bioscience reports

authors： Jacobson L,Cohen JS

更新日期：1981-02-01 00:00:00

abstract：:Increasing studies are indicating that long non-coding RNA (lncRNA) X-inactive specific transcript (XIST) is associated with the prognosis of cancer patients. However, the results have been disputed. Therefore, we aimed to further explore the prognostic value and clinical significance of XIST in various types of cance...

journal_title：Bioscience reports

authors： Liu X,Ming X,Jing W,Luo P,Li N,Zhu M,Yu M,Liang C,Tu J

更新日期：2018-06-21 00:00:00

abstract：:The human bronchial epithelial cell line, 16HBE14o- (16HBE), is widely used as a model for respiratory epithelial diseases and barrier function. During differentiation, transepithelial electrical resistance (TER) increased to approximately 800 Ohms × cm2, while 14C-d-mannitol flux rates (Jm) simultaneously decreased. ...

journal_title：Bioscience reports

authors： Callaghan PJ,Ferrick B,Rybakovsky E,Thomas S,Mullin JM

更新日期：2020-10-30 00:00:00

abstract：:Cilia and flagella are critical organelles with conserved internal structures and diverse developmental and physiological processes according to cell type. Although the core components of structures are shared with thousands of associated proteins involved in cilia or flagella formation, we hypothesized that some unkn...

journal_title：Bioscience reports

authors： Li ZZ,Zhao WL,Wang GS,Gu NH,Sun F

更新日期：2020-01-31 00:00:00

abstract：:A consensus about the prognostic role of NIMA-related kinase 2 (NEK2) expression in various solid tumors has not been made yet. Thus, this meta-analysis aimed to systematically assess the prognostic role of NEK2 expression in patients with solid tumors. The eligible studies were identified through searching PubMed, We...

journal_title：Bioscience reports

authors： Wang X,Chen K,Liu H,Huang Z,Chen X,Yin L

更新日期：2019-01-18 00:00:00

abstract：OBJECTIVE:The present study aimed to construct a diagnosis model for the early differentiation of acute radiation pneumonitis (ARP) and infectious pneumonitis based on multiple parameters. METHODS:The present study included data of 152 patients admitted to the Department of Radiochemotherapy, Tangshan People's Hospita...

journal_title：Bioscience reports

authors： Wang Z,Wu Q,Dong L,Fu H,Liu Q

更新日期：2020-04-30 00:00:00

abstract：:A natural avermectin complex, aversectin C, was shown to be capable of exerting selective cytostatic and neurotoxic effects on mammalian cells. Specifically, it killed proliferating neuroblastoma B103 cells but was non-toxic for differentiated cells of this culture. The antiproliferation action of aversectin C was not...

journal_title：Bioscience reports

authors： Kokoz YM,Tsyganova VG,Korystova AF,Grichenko AS,Zenchenko KI,Drinyaev VA,Mosin VA,Kruglyak EB,Sterlina TS,Victorov AV

更新日期：1999-12-01 00:00:00

abstract：:High-affinity binding of 3H-folate in Triton X-100 solubilized membranes of human liver displayed characteristics, e.g. apparent positive cooperativity, which are typical of specific folate binding. Ultrogel AcA 44 chromatography of solubilized membranes saturated with 3H-folate revealed a major peak of 100 kDa and a ...

journal_title：Bioscience reports

authors： Holm J,Hansen SI,Høier-Madsen M

更新日期：1991-06-01 00:00:00

abstract：:The present study estimates the effect of rivaroxaban on preventing deep vein thrombosis (DVT) in aged diabetics with femoral neck fractures after hip replacement. Our study consisted of 236 aged diabetics with femoral neck fractures, which were divided into the rivaroxaban and control groups. Reaction time (R time), ...

journal_title：Bioscience reports

authors： Zhang YM,Jiang X,Sun YS

更新日期：2017-06-21 00:00:00

abstract：:Human cytomegalovirus (HCMV) infection can cause inflammatory tissue-invasive end-organ diseases upon lytic replication. In humans, mature miR-200b-3p and -200c-3p suppress the synthesis of HCMV immediate early 2 (IE2) protein by binding to the 3'-UTR of the mRNA encoded by the unique long (UL) 122-123 region in human...

journal_title：Bioscience reports

authors： Lee KH,Lim BJ,Ferreira VH,Min SY,Hong YM,Jo JH,Han SH

更新日期：2018-12-07 00:00:00

abstract：:Permeant cationic fluorescent probes are widely employed to monitor mitochondrial transmembrane potential and its changes. The application of such potential-dependent probes in conjunction with both fluorescence microscopy and fluorescence spectroscopy allows the monitoring of mitochondrial membrane potential in indiv...

journal_title：Bioscience reports

authors： Solaini G,Sgarbi G,Lenaz G,Baracca A

更新日期：2007-06-01 00:00:00

abstract：:CYP (cytochrome P450) 3A29 in pigs could be an important candidate gene responsible for xenobiotic metabolism, similar to CYP3A4 in humans. Accordingly, the tissue expression of CYP3A29 mRNA in domestic pigs has been determined by a real-time PCR. The enzymatic properties of CYP3A29, CYP3A4 and PLM (pig liver microsom...

journal_title：Bioscience reports

authors： Yao M,Dai M,Liu Z,Huang L,Chen D,Wang Y,Peng D,Wang X,Liu Z,Yuan Z

更新日期：2011-06-01 00:00:00

abstract：:The nature of certain forms of memory is discussed in relation to neural networks and REM sleep. ...

journal_title：Bioscience reports

authors： Crick F

更新日期：1988-12-01 00:00:00

abstract：:An ontogenetic study of the effect of various neurohormones and other activators on adenylate cyclase systems was carried out using cultures of cells from 15-d-old embryonic mouse brain. Dopamine stimulated the enzyme activity at earlier culture ages (i.e. 4 and 10 d) but had little stimulatory effect at later ages (i...

journal_title：Bioscience reports

authors： Shanker G,Pieringer RA

更新日期：1985-07-01 00:00:00

abstract：:Using both immunohistological study and photoaffinity labelling with radioactive azido-ATP, evidence is presented that the mitochondrial membranes of the brown adipose tissue of the human adult contain a 32 000-Mr uncoupling protein, which is probably similar to the uncoupling protein of BAT of rodents. ...

journal_title：Bioscience reports

authors： Bouillaud F,Combes-George M,Ricquier D

更新日期：1983-08-01 00:00:00

abstract：:The present study was designed to investigate the protective effect of moracin on primary culture of nucleus pulposus cells in intervertebral disc and explore the underlying mechanism. Moracin treatment significantly inhibited the LPS-induced inflammatory cytokine accumulation (IL-1β, IL-6 and TNF-α) in nucleus pulpos...

journal_title：Bioscience reports

authors： Gu R,Huang Z,Liu H,Qing Q,Zhuan Z,Yang L,Su Z,Huang W

更新日期：2019-12-20 00:00:00

abstract：:Background: Urotensin-II (UII) rs228648 polymorphism has been reported to be associated with the risk of diabetes mellitus (DM) with inconsistent results. The present study sought to reassess the relationship between this polymorphism and susceptibility to DM by meta-analysis.Methods: Relevant eligible studies and who...

journal_title：Bioscience reports

authors： Zhao Y,Fang S,Que K,Xu G,Zhang H,Qi C,Yang N

更新日期：2018-12-07 00:00:00

abstract：:In rats fed a normal (22% protein) diet, injection of clenbuterol (1 mg/kg/d for 21 d) did not affect energy intake, energy expenditure or weight gain, but reduced energetic efficiency, and fat and energy gains and increased body protein content. Presenting a low-protein (8%) diet reduced energy intake, gain and effic...

journal_title：Bioscience reports

authors： Rothwell NJ,Stock MJ

更新日期：1987-12-01 00:00:00

abstract：:The tetracycline repressor (TetR)-regulated system is a widely used tool to study gene functions through control of its expression. Various effectors such as tetracycline (Tc) and doxycycline (Dox) quickly induce or shut down gene expression, but reversing gene expression has not been eligible due to long half-lives o...

journal_title：Bioscience reports

authors： Song C,Kim N,Park M,Lee J,Oh KB,Sim T

更新日期：2019-01-08 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) act as crucial modulators during the development of diverse cancers. Although various types of lncRNAs in prostate cancer (PCa) have been explored, quantities of lncRNAs still wait to be exploited. The present study is to probe the functions and mechanism of lncRNA HOXA cluster antisense...

journal_title：Bioscience reports

authors： Xiao S,Song B

更新日期：2020-08-28 00:00:00

abstract：OBJECTIVES:To investigate the association between dectin-1 gene single nucleotide polymorphisms (SNPs) and susceptibility to fungal infection (FI). METHODS:Databases were searched electronically and manually to identify case-control studies concerning dectin-1 SNPs and FI, which were published up to 12 November 2018. ...

journal_title：Bioscience reports

authors： Zhou P,Xie Y,Yan Z,Liu X,Hua H

更新日期：2019-11-29 00:00:00

abstract：:Sulphate efflux from human placental microvillus membrane vesicles was inhibited by external DIDS (KI congruent to 10(-6) M). This inhibition was partially reversed on addition of the translocated substrates sulphate or selenate to the external medium: selenite which is not translocated does not protect against DIDS i...

journal_title：Bioscience reports

authors： Shennan DB,Boyd CA

更新日期：1986-10-01 00:00:00

abstract：:Trypsin-releasable glycosaminoglycans from the luminal surface of intact pig aorta were measured following metabolic labelling with [35S]sulphate. Chondroitin sulphate was found to be present at a surface density equal to that already established for heparan sulphate (5 X 10(11) chains per cm2). This result was confir...

journal_title：Bioscience reports

authors： Hale G,Streeter HB,Hann AC,Gacesa P,Wusteman FS

更新日期：1987-03-01 00:00:00