Abstract:
:In rats fed a normal (22% protein) diet, injection of clenbuterol (1 mg/kg/d for 21 d) did not affect energy intake, energy expenditure or weight gain, but reduced energetic efficiency, and fat and energy gains and increased body protein content. Presenting a low-protein (8%) diet reduced energy intake, gain and efficiency, body protein content and the mass of the gastrocnemius muscle when compared to rats fed the control diet. Injection of the protein-deficient rats with clenbuterol (1 mg/kg/d for 21 d) caused hypophagia and reduced body weight and energy gains, energy expenditure and total body fat. However, the total body content of protein was not significantly reduced and the percentage of body protein in this protein deficient, clenbuterol-treated group was greater than that of untreated rats on both the high- and low-protein diets. The ratio of body protein to fat following clenbuterol treatment was increased by over 50% in both normal and protein-deficient rats. The results show that in protein deficient animals, clenbuterol treatment may help conserve body protein at the expense of fat, resulting in a smaller, but leaner body mass.
journal_name
Biosci Repjournal_title
Bioscience reportsauthors
Rothwell NJ,Stock MJdoi
10.1007/BF01122126subject
Has Abstractpub_date
1987-12-01 00:00:00pages
933-40issue
12eissn
0144-8463issn
1573-4935journal_volume
7pub_type
杂志文章abstract::Background: Nasopharyngeal carcinoma (NPC) is a disease highly sensitive to radiotherapy with the unclear etiology. However, the specific effects of microRNA-613 (miR-613) on NPC still remain elusive. Therefore, the present study probes into the underlying mechanism of miR-613 in NPC via AKT signaling pathway by regul...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20182196
更新日期:2019-07-10 00:00:00
abstract:AIM:IgA nephropathy (IgAN) is one of the most common chronic glomerulonephritis. Its etiology and pathogenesis remain unclear. We thus explored the immune repertoire of the B-cell receptor (BCR) and the heavy-chain complementarity-determining region 3 (CDR3) in renal tissue and peripheral blood of IgAN patients. METHO...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20190482
更新日期:2019-10-30 00:00:00
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更新日期:2020-08-28 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章,评审
doi:10.1007/BF01788370
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journal_title:Bioscience reports
pub_type: 杂志文章
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journal_title:Bioscience reports
pub_type: 传,历史文章
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journal_title:Bioscience reports
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journal_title:Bioscience reports
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journal_title:Bioscience reports
pub_type: 杂志文章
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journal_title:Bioscience reports
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journal_title:Bioscience reports
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journal_title:Bioscience reports
pub_type: 杂志文章
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更新日期:1983-12-01 00:00:00
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journal_title:Bioscience reports
pub_type: 临床试验,杂志文章
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20180770
更新日期:2018-08-31 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01118600
更新日期:1991-02-01 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20150080
更新日期:2015-06-12 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章,评审
doi:10.1007/s10540-007-9036-1
更新日期:2007-06-01 00:00:00
abstract::This study proposed a deep learning (DL) algorithm to predict survival in patients with colon adenocarcinoma (COAD) based on multi-omics integration. The survival-sensitive model was constructed using an autoencoder for DL implementation based on The Cancer Genome Atlas (TCGA) data of patients with COAD. The autoencod...
journal_title:Bioscience reports
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更新日期:2020-12-01 00:00:00
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journal_title:Bioscience reports
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journal_title:Bioscience reports
pub_type: 杂志文章
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journal_title:Bioscience reports
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更新日期:1996-02-01 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01114819
更新日期:1981-11-01 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01136856
更新日期:1991-08-01 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章,评审
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更新日期:2007-06-01 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
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更新日期:2019-06-07 00:00:00
abstract::Background: Urotensin-II (UII) rs228648 polymorphism has been reported to be associated with the risk of diabetes mellitus (DM) with inconsistent results. The present study sought to reassess the relationship between this polymorphism and susceptibility to DM by meta-analysis.Methods: Relevant eligible studies and who...
journal_title:Bioscience reports
pub_type: 杂志文章,meta分析
doi:10.1042/BSR20181275
更新日期:2018-12-07 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01121911
更新日期:1984-07-01 00:00:00
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journal_title:Bioscience reports
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20170105
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