Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels.

abstract：:In this observational study we investigated whether levels of factor XIII (FXIII) and its major polymorphisms affect the outcome of thrombolysis by recombinant tissue plasminogen activator (rtPA) in acute ischemic stroke (AIS) patients. Study cohort included 132 consecutive AIS patients undergoing i.v. thrombolysis wi...

journal_title：Scientific reports

authors： Székely EG,Czuriga-Kovács KR,Bereczky Z,Katona É,Mezei ZA,Nagy A,Tóth NK,Berényi E,Muszbek L,Csiba L,Bagoly Z

更新日期：2018-05-16 00:00:00

abstract：:The aim of this study was to determine the association of residual feed intake (RFI) with growth performance, blood metabolic parameters, and body composition factors in growing lambs. Individual body weight (BW) and dry matter intake (DMI) were determined in 137 male Hu lambs that were given a pellet feed four times ...

journal_title：Scientific reports

authors： Zhang X,Wang W,Mo F,La Y,Li C,Li F

更新日期：2017-10-04 00:00:00

abstract：:As antibody-based diagnosis and therapy grow at an increased pace, there is a need for methods which rapidly and accurately determine antibody-antigen interactions. Here, we report a method for the multiplex determination of antibody epitopes using bacterial cell-surface display. A protein-fragment library with 10(7) ...

journal_title：Scientific reports

authors： Hudson EP,Uhlen M,Rockberg J

更新日期：2012-01-01 00:00:00

abstract：:Deriving a 3D structural representation of an object from its 2D input is one of the great challenges for the visual system and yet, this type of representation is critical for the successful recognition of and interaction with objects. Perhaps reflecting the importance of this computation, infants have some sensitivi...

journal_title：Scientific reports

authors： Freud E,Behrmann M

更新日期：2017-09-08 00:00:00

abstract：:The present study was aimed at evaluating the fluorescence property, sporicidal potency against Bacillus and Clostridium endospores, and surface disinfecting ability of biogenic nano silver. The nano silver was synthesized using an actinobacterial cell-filtrate. The fluorescence property as well as imaging facilitator...

journal_title：Scientific reports

authors： Gopinath PM,Ranjani A,Dhanasekaran D,Thajuddin N,Archunan G,Akbarsha MA,Gulyás B,Padmanabhan P

更新日期：2016-09-26 00:00:00

abstract：:Control of parasite transmission is critical for the eradication of malaria. However, most antimalarial drugs are not active against P. falciparum gametocytes, responsible for the spread of malaria. Consequently, patients can remain infectious for weeks after the clearance of asexual parasites and clinical symptoms. H...

journal_title：Scientific reports

authors： Sun W,Tanaka TQ,Magle CT,Huang W,Southall N,Huang R,Dehdashti SJ,McKew JC,Williamson KC,Zheng W

更新日期：2014-01-17 00:00:00

abstract：:Ecological adaptations to seasonal changes are often observed in the phenotypic traits of plants and animals, and these adaptations are usually expressed through the production of different biochemical end products. In this study, ecological adaptations are observed in a biochemical pathway without alteration of the e...

journal_title：Scientific reports

authors： Hirata H,Ohnishi T,Tomida K,Ishida H,Kanda M,Sakai M,Yoshimura J,Suzuki H,Ishikawa T,Dohra H,Watanabe N

更新日期：2016-02-01 00:00:00

abstract：:At the present study, a one-dimensional model for the flat sheet direct contact membrane distillation (DCMD) for desalination purposes is proposed. Flows and membrane properties have been estimated by appropriate temperature-dependent correlations. Results show that the numerical model is in a very good agreement with...

journal_title：Scientific reports

authors： Keshavarzzadeh AH

更新日期：2020-10-08 00:00:00

abstract：:Benign prostatic hyperplasia (BPH) results in a significant public health burden due to the morbidity caused by the disease and many of the available remedies. As much as 70% of men over 70 will develop BPH. Few studies have been conducted to discover the genetic determinants of BPH risk. Understanding the biological ...

journal_title：Scientific reports

authors： Hellwege JN,Stallings S,Torstenson ES,Carroll R,Borthwick KM,Brilliant MH,Crosslin D,Gordon A,Hripcsak G,Jarvik GP,Linneman JG,Devi P,Peissig PL,Sleiman PAM,Hakonarson H,Ritchie MD,Verma SS,Shang N,Denny JC,Roden DM

更新日期：2019-04-15 00:00:00

abstract：:Tissue ischemia results in an accumulation of lactate and local or systemic lactic acidosis. In nociceptive sensory neurons, lactate was reported to sensitize or activate the transient receptor potential ion channel TRPA1 and acid-sensing ion channels (ASICs). However, it is unclear how lactate modulates the TRPV1 reg...

journal_title：Scientific reports

authors： de la Roche J,Walther I,Leonow W,Hage A,Eberhardt M,Fischer M,Reeh PW,Sauer S,Leffler A

更新日期：2016-11-09 00:00:00

abstract：:Ten-year oncological experience of the University Medical Center Groningen with conventional laparotomy (C-RRRTM) and laparoscopy (L-RRRTM) is described concerning resection of residual retroperitoneal tumor masses (RRTM) in a large series of patients with advanced nonseminomatous testicular germ cell tumors (NSTGCT)....

journal_title：Scientific reports

authors： Öztürk Ç,Been LB,van Ginkel RJ,Gietema JA,Hoekstra HJ

更新日期：2019-11-01 00:00:00

abstract：:Tetrandrine (Tet) could enhance the antitumor effect of Paclitaxel (Ptx) by increasing intracellular Reactive Oxygen Species (ROS) levels, which leads to the possibility of co-delivery of both drugs for synergistic antitumor effect. In the current study, we reported an efficient, local therapeutic strategy employing e...

journal_title：Scientific reports

authors： Zhang H,Tian Y,Zhu Z,Xu H,Li X,Zheng D,Sun W

更新日期：2016-05-26 00:00:00

abstract：:This paper presents an ultracompact tunable device for power splitting and switching by tuning the Fermi energy level of monolayer patternless graphene underneath a slotted multimode interference (MMI) coupler operating in the mid-infrared, λ = 9-11 μm. By introducing a high-index silicon slot in the central region of...

journal_title：Scientific reports

authors： Huang CC,Sun TC

更新日期：2019-09-04 00:00:00

abstract：:Medicinal herbs belonging to the same genus are always easily confused due to their extremely similar morphology and metabolites. Previously, to differentiate them, inherently specific biomarkers were screened out via intuitive comparison of their metabolite profiles. Unfortunately, the selected biomarkers have worked...

journal_title：Scientific reports

authors： Wang HP,Liu Y,Chen C,Xiao HB

更新日期：2017-07-04 00:00:00

abstract：:Invasive pulmonary Aspergillosis is a leading cause of morbidity and mortality in immunosuppressed patients and treatment outcomes using oral antifungal triazoles remain suboptimal. Here we show that combining topical treatment using PC945, a novel inhaled triazole, with systemic treatment using known triazoles demons...

journal_title：Scientific reports

authors： Colley T,Sehra G,Daly L,Kimura G,Nakaoki T,Nishimoto Y,Kizawa Y,Strong P,Rapeport G,Ito K

更新日期：2019-07-01 00:00:00

abstract：:Kidney transplantations using expanded criteria donors (ECD) are being increasingly adopted, but no consensus tools are available to evaluate donor kidney status. Beta-2 microglobulin (B2MG) is a marker of kidney function, and herein, we evaluate the usefulness of assessing B2MG to evaluate donor kidney status. Fifty-...

journal_title：Scientific reports

authors： Cha SW,Shin IS,Kim DG,Kim SH,Lee JY,Kim JS,Yang JW,Han BG,Choi SO

更新日期：2020-05-15 00:00:00

abstract：:Magnetron sputtering techniques were used to prepare molecularly smooth titanium thin films possessing an average roughness between 0.18 nm and 0.52 nm over 5 μm × 5 μm AFM scanning areas. Films with an average roughness of 0.52 nm or lower were found to restrict the extent of P. aeruginosa cell attachment, with less ...

journal_title：Scientific reports

authors： Ivanova EP,Truong VK,Webb HK,Baulin VA,Wang JY,Mohammodi N,Wang F,Fluke C,Crawford RJ

更新日期：2011-01-01 00:00:00

abstract：:The high hydrophobicity of poly(vinylidene fluoride) (PVDF) membrane remains an obstacle to be applied in some purification processes of water or wastewater. Herein, a highly hydrophilic hybrid mesoporous titania membrane composed of mesoporous anatase titania (meso-TiO2) materials inside the three-dimensional (3D) ma...

journal_title：Scientific reports

authors： Wang M,Yang G,Jin P,Tang H,Wang H,Chen Y

更新日期：2016-01-12 00:00:00

abstract：:Maculinea (=Phengaris) are endangered butterflies that are characterized by a very complex biological cycle. Maculinea larvae behave as obligate parasites whose survival is strictly dependent on both particular food plants and species-specific Myrmica ants. In this interaction, Maculinea caterpillars induce Myrmica wo...

journal_title：Scientific reports

authors： Di Salvo M,Calcagnile M,Talà A,Tredici SM,Maffei ME,Schönrogge K,Barbero F,Alifano P

更新日期：2019-05-29 00:00:00

abstract：:Food and flavour pairing are commonly used as an empirically based phenomenology by chefs and food innovators for creating delicious dishes. However, there is little if any science behind the pairing systems used, and it appears that pairing is determined by food culture and tradition rather than by chemical food comp...

journal_title：Scientific reports

authors： Schmidt CV,Olsen K,Mouritsen OG

更新日期：2020-11-18 00:00:00

abstract：:Adapters bind motor proteins to cargoes and therefore play essential roles in Kinesin-1 mediated intracellular transport. The regulatory mechanisms governing adapter functions and the spectrum of cargoes recognized by individual adapters remain poorly defined. Here, we show that cargoes transported by the Kinesin-1 ad...

journal_title：Scientific reports

authors： Butkevich E,Härtig W,Nikolov M,Erck C,Grosche J,Urlaub H,Schmidt CF,Klopfenstein DR,Chua JJ

更新日期：2016-06-01 00:00:00

abstract：:Voltage-gated sodium (NaV) channels have been related with cell migration and invasiveness in human cancers. We previously reported the contribution of NaV1.6 channels activity with the invasion capacity of cervical cancer (CeCa) positive to Human Papilloma Virus type 16 (HPV16), which accounts for 50% of all CeCa cas...

journal_title：Scientific reports

authors： Lopez-Charcas O,Espinosa AM,Alfaro A,Herrera-Carrillo Z,Ramirez-Cordero BE,Cortes-Reynosa P,Perez Salazar E,Berumen J,Gomora JC

更新日期：2018-08-29 00:00:00

abstract：:Inbred strains of mice are powerful models for understanding human pregnancy complications. For example, the exclusive mating of CBA/J females to DBA/2J males increases fetal resorption to 20-35% with an associated decline in placentation and maintenance of maternal Th1 immunity. More recently other complications of p...

journal_title：Scientific reports

authors： McKelvey KJ,Yenson VM,Ashton AW,Morris JM,McCracken SA

更新日期：2016-10-21 00:00:00

abstract：:Histamine is an important neurotransmitter that contributes to various processes, including the sleep-wake cycle, learning, memory, and stress responses. Its actions are mediated through histamine H1-H4 receptors. Gene knockout and pharmacological studies have revealed the importance of H1 receptors in learning and me...

journal_title：Scientific reports

authors： Kárpáti A,Yoshikawa T,Naganuma F,Matsuzawa T,Kitano H,Yamada Y,Yokoyama M,Futatsugi A,Mikoshiba K,Yanai K

更新日期：2019-11-11 00:00:00

abstract：:Direct measures of energy expenditure are difficult to obtain in marine mammals, and accelerometry may be a useful proxy. Recently its utility has been questioned as some analyses derived their measure of activity level by calculating the sum of accelerometry-based values and then comparing this summation to summed (t...

journal_title：Scientific reports

authors： Ladds MA,Rosen DAS,Slip DJ,Harcourt RG

更新日期：2017-09-18 00:00:00

abstract：:We hereby report for the first time on the design, manufacturing and testing of a three-dimensional (3D) nearly-periodic, locally resonant phononic crystal (PnC). Most of the research effort on PnCs and metamaterials has been focused on the enhanced dynamic properties arising from their periodic design. Lately, additi...

journal_title：Scientific reports

authors： Meng H,Bailey N,Chen Y,Wang L,Ciampa F,Fabro A,Chronopoulos D,Elmadih W

更新日期：2020-11-04 00:00:00

abstract：:Acoustic manipulation by an ultrasonic phased array provides an entirely new approach to processes such as coalescence, mixing, separation, and evaporation occurring in the generation of new materials, physical property measurement, the biomedical industry, etc. However, to date, ultrasonic phased arrays have not been...

journal_title：Scientific reports

authors： Watanabe A,Hasegawa K,Abe Y

更新日期：2018-07-05 00:00:00

abstract：:Breast cancer brain metastasis (BCBM) remains a major clinical problem. Approximately 10-16% of patients with breast cancer develop brain metastases (BCBM). However, no systemic therapy has gained regulatory approval for the specific treatment of BCBM and this remains an area of persistent, unmet medical need. Rapid, ...

journal_title：Scientific reports

authors： Liu Z,Wang Y,Kabraji S,Xie S,Pan P,Liu Z,Ni J,Zhao JJ

更新日期：2019-01-24 00:00:00

abstract：:Keyboards and smartphones allow users to express their thoughts freely via manual control. Hands-free communication can be realized with brain-computer interfaces (BCIs) based on code-modulated visual evoked potentials (c-VEPs). Various variations of such spellers have been developed: Low-target systems, multi-target ...

journal_title：Scientific reports

authors： Gembler FW,Benda M,Rezeika A,Stawicki PR,Volosyak I

更新日期：2020-10-13 00:00:00

abstract：:Biology is adapted to Earth's gravity force, and the long-term effects of varying gravity on the development of animals is unclear. Previously, we reported that high gravity, called hypergravity, increases defects in the development of motor neuron axons in the nematode Caenorhabditis elegans. Here, we show that a mut...

journal_title：Scientific reports

authors： Kalichamy SS,Alcantara AV Jr,Kim BS,Park J,Yoon KH,Lee JI

更新日期：2020-12-03 00:00:00