Abstract:
:This paper presents an ultracompact tunable device for power splitting and switching by tuning the Fermi energy level of monolayer patternless graphene underneath a slotted multimode interference (MMI) coupler operating in the mid-infrared, λ = 9-11 μm. By introducing a high-index silicon slot in the central region of the MMI structure, which can significantly shorten the beat length, the proposed device has an approximately 4.5-fold reduction in device length and a two-fold improvement in power transmission compared with conventional MMI couplers without slotting. The device has a footprint of only 0.30 × 0.65 μm2 (<λ/10), making it the smallest power splitter and switcher. Over the bandwidth of 2 μm, the power transmission of the proposed device is nearly uniform. Extending the operating bandwidth is limited only by the practically achievable Fermi energy of graphene. For the fabrication tolerance, the numerical results show that the relative power variations are lower than 5%, even though the dimension variations are greater than 15%. With its advantages of tunability, compact footprint, and broadband operation, the proposed device is suitable for highly dense photonic integrated circuits.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Huang CC,Sun TCdoi
10.1038/s41598-019-49186-xsubject
Has Abstractpub_date
2019-09-04 00:00:00pages
12756issue
1issn
2045-2322pii
10.1038/s41598-019-49186-xjournal_volume
9pub_type
杂志文章abstract::Dairy cows are often fed a high-concentrate (HC) diet to meet lactation demands; however, long-term concentrate feeding is unhealthy and decreases milk fat. Therefore, we investigated the effects of liver lipid metabolism on milk fat synthesis. Ten lactating Holstein cows were assigned randomly into HC and LC (low-con...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44217
更新日期:2017-03-13 00:00:00
abstract::We propose a novel method to achieve tunable plasmon focusing in graphene/photonic-crystal hybrid structure exhibiting all-angle negative refraction at terahertz frequencies. A two-dimensional photonic crystal composed of a square lattice of dielectric rods is constructed on the substrate of a graphene sheet to provid...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41788
更新日期:2017-02-02 00:00:00
abstract::In adipose tissue, agonists of the β3-adrenergic receptor (ADRB3) regulate lipolysis, lipid oxidation, and thermogenesis. The deficiency in the thermogenesis induced by neuroblast differentiation-associated protein AHNAK in white adipose tissue (WAT) of mice fed a high-fat diet suggests that AHNAK may stimulate energy...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23426
更新日期:2016-03-18 00:00:00
abstract::Foliar fungi of silver birch (Betula pendula) in an experimental Finnish forest were investigated across a gradient of tree species richness using molecular high-throughput sequencing and visual macroscopic assessment. We hypothesized that the molecular approach detects more fungal taxa than visual assessment, and tha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41801
更新日期:2017-02-02 00:00:00
abstract::We study the dynamics of an ultrafast single photon pulse in a one-dimensional waveguide two-point coupled with a Jaynes-Cummings system. We find that for any single photon input the transmissivity depends periodically on the separation between the two coupling points. For a pulse containing many plane wave components...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33867
更新日期:2016-09-22 00:00:00
abstract::Early brain development requires a tight orchestration between neural tube patterning and growth. How pattern formation and brain growth are coordinated is incompletely understood. Previously we showed that aristaless-related homeobox (ARX), a paired-like transcription factor, regulates cortical progenitor pool expans...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36194-6
更新日期:2019-01-18 00:00:00
abstract::Magnetite (Fe3O4) is an iron ore mineral that is globally mined especially for steel production. It is denser (5.15 g/cm3) than Earth's crust (~2.7 g/cm3) and is expected to accumulate at the bottom of melt-rich magma reservoirs. However, recent studies revealed heterogeneous fluid bubble nucleation on oxide minerals ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40376-1
更新日期:2019-03-07 00:00:00
abstract::CVB3 is a common human pathogen to be highly lethal to newborns and causes viral myocarditis and pancreatitis in adults. However, there is no vaccine available for clinical use. CVB3 capsid protein VP1 is an immunodominant structural protein, containing several B- and T-cell epitopes. However, immunization of mice wit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41485
更新日期:2017-02-02 00:00:00
abstract::Metal-organic frameworks (MOFs) are intriguing host materials in composite electrolytes due to their ability for tailoring host-guest interactions by chemical tuning of the MOF backbone. Here, we introduce particularly high sodium ion conductivity into the zeolitic imidazolate framework ZIF-8 by impregnation with the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-60198-w
更新日期:2020-02-26 00:00:00
abstract::The aim of the present work was to study whether the leptin-adiponectin axis may have a pathophysiological role in the increased systemic inflammation and oxidative stress observed in patients with the metabolic syndrome (MS). Leptin, adiponectin, and markers of inflammation and oxidative stress were measured in a sam...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06997-0
更新日期:2017-07-26 00:00:00
abstract::Bone is the most common site of metastasis in metastatic castration-resistant prostate cancer (mCRPC), which is associated with pain and skeletal events. Radium-223 dichloride (Xofigo) is an alpha-emitting radioactive isotope that can specifically target bone lesions. Herein, we report the results of a retrospective a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63302-2
更新日期:2020-04-21 00:00:00
abstract::We discuss a scheme to retrieve transient conformational molecular structure information using photoelectron angular distributions (PADs) that have averaged over partial alignments of isolated molecules. The photoelectron is pulled out from a localized inner-shell molecular orbital by an X-ray photon. We show that a t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23655
更新日期:2016-03-30 00:00:00
abstract::Due to the increasing environmental impact of food production, carbon footprint as an indicator can guide farmland management. This study established a method and estimated the carbon footprint of grain production in China based on life cycle analysis (LCA). The results showed that grain production has a high carbon f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04182-x
更新日期:2017-06-29 00:00:00
abstract::Medial arterial calcification (MAC) is a common outcome in diabetes and chronic kidney disease (CKD). It occurs as linear mineral deposits along the degraded elastin lamellae and is responsible for increased aortic stiffness and subsequent cardiovascular events. Current treatments for calcification, particularly in CK...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39639-8
更新日期:2019-02-22 00:00:00
abstract::Recently, the use of a liquid biopsy has shown promise in monitoring tumor burden. While point mutations have been extensively studied, chromosomal rearrangements have demonstrated greater tumor specificity. Such rearrangements can be identified in the tumor and subsequently detected in the plasma of patients using qu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29831
更新日期:2016-07-20 00:00:00
abstract::Hepatitis C virus (HCV) uses components of the very-low-density lipoprotein (VLDL) pathway for assembly/release. We previously reported that hepatocyte nuclear factor 4α (HNF4α) participates in HCV assembly/release through downstream factors those participate in VLDL assembly/secretion. Cell-death-inducing DFFA-like e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27778
更新日期:2016-06-10 00:00:00
abstract::Genetically encoded calcium indicators and optogenetic actuators can report and manipulate the activity of specific neuronal populations. However, applying imaging and optogenetics simultaneously has been difficult to establish in the mammalian brain, even though combining the techniques would provide a powerful appro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40041
更新日期:2017-01-05 00:00:00
abstract::Glucokinase (GK), the hexokinase involved in glucosensing in pancreatic β-cells, is also expressed in arcuate nucleus (AN) neurons and hypothalamic tanycytes, the cells that surround the basal third ventricle (3V). Several lines of evidence suggest that tanycytes may be involved in the regulation of energy homeostasis...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03928-x
更新日期:2017-06-16 00:00:00
abstract::The annotation of protein function is a vital step to elucidate the essence of life at a molecular level, and it is also meritorious in biomedical and pharmaceutical industry. Developments of sequencing technology result in constant expansion of the gap between the number of the known sequences and their functions. Th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37179
更新日期:2016-11-16 00:00:00
abstract::Coral reefs across the world's oceans are in the midst of the longest bleaching event on record (from 2014 to at least 2016). As many of the world's reefs are remote, there is limited information on how past thermal conditions have influenced reef composition and current stress responses. Using satellite temperature d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38402
更新日期:2016-12-06 00:00:00
abstract::Brønsted-Lewis acidic ionic liquids (ILs) were applied to catalyze cellobiose to prepare levulinic acid (LA) in one pot under hydrothermal conditions. Under the optimum conditions, the highest LA yield of 67.51% was obtained when low [HO3S-(CH2)3-mim]Cl-FeCl3 (molar fraction of FeCl3 x = 0.60) was used. This indicated...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38051-y
更新日期:2019-02-12 00:00:00
abstract::Sufficient tissue oxygenation is required for regular brain function; thus oxygen supply must be tightly regulated to avoid hypoxia and irreversible cell damage. If hypoxia occurs the transcription factor complex hypoxia-inducible factor (HIF) will accumulate and coordinate adaptation of cells to hypoxia. However, eve...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75838-4
更新日期:2020-11-05 00:00:00
abstract::The Near-infrared Fluorescence (NIRF) molecular imaging of cancer is known to be superior in sensitivity, deeper penetration, and low phototoxicity compared to other imaging modalities. In view of an increased need for efficient and targeted imaging agents, we synthesized a NAD(P)H quinone oxidoreductase 1 (NQO1)-acti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44111-8
更新日期:2019-06-12 00:00:00
abstract::This study aimed to evaluate the effects of ischemia-reperfusion injury (IRI) on the risk of hepatocellular carcinoma (HCC) recurrence after liver transplantation. Data of 195 patients were retrospectively analysed. Post-reperfusion aspartate (AST), alanine transaminase, and lactate dehydrogenase (LDH) levels were the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27319-y
更新日期:2018-06-12 00:00:00
abstract::Liquid biopsy can provide a strong basis for precision medicine. We aimed to identify novel single-nucleotide variants (SNVs) in circulating tumor DNA (ctDNA) in patients with hepatocellular carcinoma (HCC). Deep sequencing of plasma-derived ctDNA from 59 patients with HCC was performed using a panel of 2924 SNVs in 6...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74494-y
更新日期:2020-10-20 00:00:00
abstract::ERF transcription factors play critical roles in plant immune responses. Here, we report the function of AtERF014, a nucleus-localized transcriptional activator, in Arabidopsis immunity. Expression of AtERF014 was induced by Pseudomonas syringae pv. tomato (Pst) and Botrytis cinerea (Bc). AtERF014-overexpressing (OE) ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30251
更新日期:2016-07-22 00:00:00
abstract::The black rhinoceros is again on the verge of extinction due to unsustainable poaching in its native range. Despite a wide historic distribution, the black rhinoceros was traditionally thought of as depauperate in genetic variation, and with very little known about its evolutionary history. This knowledge gap has hamp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41417
更新日期:2017-02-08 00:00:00
abstract::Biochar can influence native soil organic carbon (SOC) mineralisation through "priming effects". However, the long-term direction, persistence and extent of SOC priming by biochar remain uncertain. Using natural (13)C abundance and under controlled laboratory conditions, we show that biochar-stimulated SOC mineralisat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03687
更新日期:2014-01-21 00:00:00
abstract::Abscisic acid (ABA) is an ancient stress hormone and is detectable in a wide variety of organisms where it regulates innate immunity and inflammation. Previously, we showed that oral supplementation with ABA decreased parasitemia in a mouse model of malaria, decreased liver and spleen pathology and reduced parasite tr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27073-1
更新日期:2018-06-11 00:00:00
abstract::Enterovirus A89 (EV-A89) is a novel member of the EV-A species. To date, only one full-length genome sequence (the prototype strain) has been published. Here, we report the molecular identification and genomic characterization of a Chinese EV-A89 strain, KSYPH-TRMH22F/XJ/CHN/2011, isolated in 2011 from a contact of an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18558
更新日期:2015-12-21 00:00:00