Simultaneous high-speed imaging and optogenetic inhibition in the intact mouse brain.

abstract：:A new compact silicon grating coupler enabling fibre-to-chip light coupling at a minimized taper length is proposed. The proposed coupler, which incorporates a hollow tapered waveguide, converts the spot-size of optical modes from micro- to nano-scales by reducing the lateral dimension from 15 µm to 300 nm at a length...

journal_title：Scientific reports

authors： Asaduzzaman M,Bakaul M,Skafidas E,Khandokar MRH

更新日期：2018-02-07 00:00:00

abstract：:A novel fungal species, Aspergillus labruscus sp. nov., has been found in Brazil during an investigation of the fungal species present on the surface of grape berries (Vitis labrusca L.) for use in the production of concentrated grape juice. It seems to be associated to V. labrusca, and has never been recovered from V...

journal_title：Scientific reports

authors： Fungaro MHP,Ferranti LS,Massi FP,da Silva JJ,Sartori D,Taniwaki MH,Frisvad JC,Iamanaka BT

更新日期：2017-07-24 00:00:00

abstract：:Large bowel preparation may cause a substantial change in the gut microbiota and metabolites. Here, we included a bowel prep group and a no-procedure control group and evaluated the effects of bowel prep on the stability of the gut microbiome and metabolome as well as on recovery. Gut microbiota and metabolome composi...

journal_title：Scientific reports

authors： Nagata N,Tohya M,Fukuda S,Suda W,Nishijima S,Takeuchi F,Ohsugi M,Tsujimoto T,Nakamura T,Shimomura A,Yanagisawa N,Hisada Y,Watanabe K,Imbe K,Akiyama J,Mizokami M,Miyoshi-Akiyama T,Uemura N,Hattori M

更新日期：2019-03-11 00:00:00

abstract：:Species in the genus Suaeda have few diagnostic characters and substantial morphological plasticity. Hence, regional floras do not provide clear taxonomic information for Suaeda spp. in East Asia. In order to assess the taxonomy of four species in the genus Suaeda (S. australis, S. maritima, S. japonica, and S. hetero...

journal_title：Scientific reports

authors： Park JS,Jin DP,Choi BH

更新日期：2020-12-01 00:00:00

abstract：:Ossification of the posterior longitudinal ligament (OPLL) can occur throughout the entire spine and can sometimes lead to spinal disorder. Although patients with OPLL sometimes develop physical limitations because of pain, the characteristics of pain and effects on activities of daily living (ADL) have not been preci...

journal_title：Scientific reports

authors： Hirai T,Yoshii T,Ushio S,Mori K,Maki S,Katsumi K,Nagoshi N,Takeuchi K,Furuya T,Watanabe K,Nishida N,Watanabe K,Kaito T,Kato S,Nagashima K,Koda M,Ito K,Imagama S,Matsuoka Y,Wada K,Kimura A,Ohba T,Katoh H,Mats

更新日期：2020-03-26 00:00:00

abstract：:By means of first principles calculation and experiments, a detailed mechanism is proposed to include the stages of slip, adjustment, and expansion for the HCP → FCC phase transformation with the prismatic relation of [Formula: see text] and [Formula: see text] in titanium. It is revealed that the formation of four FC...

journal_title：Scientific reports

authors： Yang JX,Zhao HL,Gong HR,Song M,Ren QQ

更新日期：2018-01-31 00:00:00

abstract：:The role of marginal populations for the long-term maintenance of species' genetic diversity and evolutionary potential is particularly timely in view of the range shifts caused by climate change. The Centre-Periphery hypothesis predicts that marginal populations should bear reduced genetic diversity and have low evol...

journal_title：Scientific reports

authors： Ciborowski K,Jordan WC,Garcia de Leaniz C,Consuegra S

更新日期：2017-02-10 00:00:00

abstract：:Human mesenchymal stem cells (hMSCs) are widely used in regenerative medicine. In some applications, they must survive under low nutrient conditions engendered by avascularity. Strategies to improve hMSCs survival may be of high relevance in tissue engineering. Carnitine palmitoyltransferase 1 C (CPT1C) is a pseudoenz...

journal_title：Scientific reports

authors： Roa-Mansergas X,Fadó R,Atari M,Mir JF,Muley H,Serra D,Casals N

更新日期：2018-05-03 00:00:00

abstract：:Retinitis pigmentosa (RP) is a heterogeneous group of inherited disorders caused by mutations in a variety of genes that are mostly expressed by rod cells, which results in initial death of rod photoreceptors followed by gradual death of cone photoreceptors. RP is currently untreatable and usually leads to partial or ...

journal_title：Scientific reports

authors： Wang K,Xiao J,Peng B,Xing F,So KF,Tipoe GL,Lin B

更新日期：2014-12-23 00:00:00

abstract：:FFAR3 (GPR41) is a G-protein coupled receptor for which short-chain fatty acids serve as endogenous ligands. The receptor is found on gut enteroendocrine L-cells, pancreatic β-cells, and sympathetic neurons, and is implicated in obesity, diabetes, allergic airway disease, and altered immune function. In primates, FFAR...

journal_title：Scientific reports

authors： Puhl HL 3rd,Won YJ,Lu VB,Ikeda SR

更新日期：2015-08-11 00:00:00

abstract：:There is still much to understand about the brain's colour processing mechanisms and the transformation from cone-opponent representations to perceptual hues. Moreover, it is unclear which area(s) in the brain represent unique hues. We propose a hierarchical model inspired by the neuronal mechanisms in the brain for l...

journal_title：Scientific reports

authors： Mehrani P,Mouraviev A,Tsotsos JK

更新日期：2020-05-22 00:00:00

abstract：:Based on the electrical characteristic detection technology, the quantitative prediction models of sensory score and physical and chemical quality Index (theaflavins, thearubigins, and theabrownins) were established by using the fermented products of Congou black tea as the research object. The variation law of electr...

journal_title：Scientific reports

authors： Dong C,An T,Zhu H,Wang J,Hu B,Jiang Y,Yang Y,Li J

更新日期：2020-01-31 00:00:00

abstract：:The peptide hormone oxytocin is an established regulator of social function in mammals, and dysregulated oxytocin signaling is implicated in autism spectrum disorder (ASD). Several clinical trials examining the effects of intranasal oxytocin for improving social and behavioral function in ASD have had mixed or inclusi...

journal_title：Scientific reports

authors： Voinsky I,Bennuri SC,Svigals J,Frye RE,Rose S,Gurwitz D

更新日期：2019-09-17 00:00:00

abstract：:Precise mitotic spindle orientation is essential for both cell fate and tissue organization while defects in this process are associated with tumorigenesis and other diseases. In most animal cell types, the dynein motor complex is anchored at the cell cortex and exerts pulling forces on astral microtubules to position...

journal_title：Scientific reports

authors： Vodicska B,Cerikan B,Schiebel E,Hoffmann I

更新日期：2018-04-20 00:00:00

abstract：:Atmospheric new particle formation (NPF) and growth significantly influences climate by supplying new seeds for cloud condensation and brightness. Currently, there is a lack of understanding of whether and how marine biota emissions affect aerosol-cloud-climate interactions in the Arctic. Here, the aerosol population ...

journal_title：Scientific reports

authors： Dall Osto M,Beddows DCS,Tunved P,Krejci R,Ström J,Hansson HC,Yoon YJ,Park KT,Becagli S,Udisti R,Onasch T,O Dowd CD,Simó R,Harrison RM

更新日期：2017-06-12 00:00:00

abstract：:Root-knot nematodes (RKNs) are obligate biotrophic parasites that invade plant roots and engage in prolonged and intimate relationships with their hosts. Nematode secretions, some of which have immunosuppressing activity, play essential roles in successful parasitism; however, their mechanisms of action remain largely...

journal_title：Scientific reports

authors： Niu J,Liu P,Liu Q,Chen C,Guo Q,Yin J,Yang G,Jian H

更新日期：2016-01-22 00:00:00

abstract：:Hydrogen is known to be present as an impurity in amorphous oxide semiconductors at the 0.1% level. Using amorphous ZnO as a simplified model system, we show that the hydrogens pair up at oxygen vacancies in the amorphous network, where they form metal-H-metal bridge bonds. These bonds are shown to create filled defec...

journal_title：Scientific reports

authors： Li H,Guo Y,Robertson J

更新日期：2017-12-04 00:00:00

abstract：:In the present work, we demonstrated the biosynthesis of silver nanoparticles (AgNPs) by highly stable, economic and eco-friendly method using leaf extract of Terminalia arjuna (T. arjuna) and employing as a catalyst for the degradation of methyl orange (MO), methylene blue (MB), congo red (CR) and 4- nitrophenol (4-N...

journal_title：Scientific reports

authors： Raj S,Singh H,Trivedi R,Soni V

更新日期：2020-06-15 00:00:00

abstract：:Japan has often been viewed as an Asian country that possesses a genetically homogenous community. The basis for partitioning the country into prefectures has largely been geographical, although cultural and linguistic differences still exist between some of the districts/prefectures, especially between Okinawa and th...

journal_title：Scientific reports

authors： Saw WY,Liu X,Khor CC,Takeuchi F,Katsuya T,Kimura R,Nabika T,Ohkubo T,Tabara Y,Yamamoto K,Yokota M,Japanese Genome Variation Consortium.,Teo YY,Kato N

更新日期：2015-12-09 00:00:00

abstract：:Multinational corporations use highly complex structures of parents and subsidiaries to organize their operations and ownership. Offshore Financial Centers (OFCs) facilitate these structures through low taxation and lenient regulation, but are increasingly under scrutiny, for instance for enabling tax avoidance. There...

journal_title：Scientific reports

authors： Garcia-Bernardo J,Fichtner J,Takes FW,Heemskerk EM

更新日期：2017-07-24 00:00:00

abstract：:Enterovirus 71 (EV71) is a human pathogen that causes hand, foot, mouth disease and neurological complications. Although EV71, as well as other enteroviruses, initiates a remodeling of intracellular membrane for genomic replication, the regulatory mechanism remains elusive. By screening human cDNA library, we uncover ...

journal_title：Scientific reports

authors： Lei X,Xiao X,Zhang Z,Ma Y,Qi J,Wu C,Xiao Y,Zhou Z,He B,Wang J

更新日期：2017-03-17 00:00:00

abstract：:Pesticides, including neonicotinoids, typically target pest insects by being neurotoxic. Inadvertent exposure to foraging insect pollinators is usually sub-lethal, but may affect cognition. One cognitive trait, spatial working memory, may be important in avoiding previously-visited flowers and other spatial tasks such...

journal_title：Scientific reports

authors： Samuelson EE,Chen-Wishart ZP,Gill RJ,Leadbeater E

更新日期：2016-12-13 00:00:00

abstract：:Methylation of DNA CpG sites is a major mechanism of epigenetic gene silencing and plays important roles in cell division, development and carcinogenesis. One of its regulators is the 64-residue C-terminal Transcriptional Repressor Domain (the TRD) of MBD1, which recruits several repressor proteins such as MCAF1, HDAC...

journal_title：Scientific reports

authors： Hameed UF,Lim J,Zhang Q,Wasik MA,Yang D,Swaminathan K

更新日期：2014-05-09 00:00:00

abstract：:Studies on the evolution of parental care have focused primarily on the costs and benefits of parental care and the life-history attributes that favour it. However, once care evolves, offspring in some taxa appear to become increasingly dependent on their parents. Although offspring dependency is a central theme in fa...

journal_title：Scientific reports

authors： Capodeanu-Nägler A,Keppner EM,Vogel H,Ayasse M,Eggert AK,Sakaluk SK,Steiger S

更新日期：2016-07-05 00:00:00

abstract：:Various nickel and magnesium dual-doped LiNixMg0.08Mn1.92-xO4 (x ≤ 0.15) were synthesized via a modified solid-state combustion method. All as-prepared samples show typical spinel phase with a well-defined polyhedron morphology. The Ni-Mg dual-doping obviously decreases the lattice parameter that gives rise to the lat...

journal_title：Scientific reports

authors： Yu Y,Guo J,Xiang M,Su C,Liu X,Bai H,Bai W,Duan K

更新日期：2019-11-14 00:00:00

abstract：:Andrographolide is a traditional herb medicine, widely used in Asia for conditions involving inflammation. The andrographlide-lipoic acid conjugate, AL-1, has been found being able to alleviate inflammation in our previous reports. Although the anti-inflammatory activity of AL-1 contributes to its cytoprotective effec...

journal_title：Scientific reports

authors： Yang Y,Yan H,Jing M,Zhang Z,Zhang G,Sun Y,Shan L,Yu P,Wang Y,Xu L

更新日期：2016-07-20 00:00:00

abstract：:This study aimed to evaluate the application value of diffusion-weighted imaging (DWI) for assessing paradoxical puborectalis syndrome (PPS) in patients with obstructive defecation syndrome (ODS). The medical records of 72 ODS patients who underwent magnetic resonance (MR)-DWI and MR-defecography were retrospectively ...

journal_title：Scientific reports

authors： Liu G,Cui Z,Dai Y,Yao Q,Xu J,Wu G

更新日期：2017-06-07 00:00:00

abstract：:In the Ultimatum Game, two players are offered a chance to win a pie. The proposer suggests how to split the pie. The responder can either accept or reject the deal. If an agreement is not reached, neither player gets anything. Both game theory and evolutionary game theory predict the rational solution that the propos...

journal_title：Scientific reports

authors： Wang X,Chen X,Wang L

更新日期：2014-04-01 00:00:00

abstract：:Fetal cardiomyocytes actively proliferate to form the primitive heart in utero in mammals, but they stop dividing shortly after birth. The identification of essential molecules maintaining this active cardiomyocyte proliferation is indispensable for potential adult heart regeneration. A recent study has shown that thi...

journal_title：Scientific reports

authors： Hashimoto K,Kodama A,Honda T,Hanashima A,Ujihara Y,Murayama T,Nishimatsu SI,Mohri S

更新日期：2017-06-30 00:00:00

abstract：:Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of these lines with their other properties. The analysis revealed a r...

journal_title：Scientific reports

authors： Zielinski DC,Jamshidi N,Corbett AJ,Bordbar A,Thomas A,Palsson BO

更新日期：2017-01-25 00:00:00