Sperm-borne miR-449b influences cleavage, epigenetic reprogramming and apoptosis of SCNT embryos in bovine.

abstract：:A series of three remarkable complexes [PMo12O40]@[Cu6O(TZI)3(H2O)9]4·OH·31H2O (H3TZI = 5-tetrazolylisophthalic acid; denoted as HLJU-1, HLJU = Heilongjiang University), [SiMo12O40]@[Cu6O(TZI)3(H2O)9]4·32H2O (denoted as HLJU-2), and [PW12O40]@[Cu6O(TZI)3(H2O)6]4·OH·31H2O (denoted as HLJU-3) have been isolated by using...

journal_title：Scientific reports

authors： Sun JW,Yan PF,An GH,Sha JQ,Li GM,Yang GY

更新日期：2016-05-09 00:00:00

abstract：:Human activating signal cointegrator homology (ASCH) domain-containing proteins are widespread and diverse but, at present, the vast majority of those proteins have no function assigned to them. This study demonstrates that the 103-amino acid Escherichia coli protein YqfB, previously identified as hypothetical, is a u...

journal_title：Scientific reports

authors： Stanislauskienė R,Laurynėnas A,Rutkienė R,Aučynaitė A,Tauraitė D,Meškienė R,Urbelienė N,Kaupinis A,Valius M,Kaliniene L,Meškys R

更新日期：2020-01-21 00:00:00

abstract：:The study aimed to compare the tumor response to and complications of doxorubicin-eluting CalliSphere bead-transarterial chemoembolization (DEB-TACE) using small- and medium-sized beads in patients with hepatocellular carcinoma (HCC) who underwent multiple rounds of oncology therapies. Sixty patients with intermediate...

journal_title：Scientific reports

authors： Wang CY,Xia JG,Yang ZQ,Zhou WZ,Chen WH,Qi CJ,Gu JP,Wang Q

更新日期：2020-03-10 00:00:00

abstract：:The Expanded Susceptibility to Smoking Index (ESSI) is based on the combination of susceptibility to smoking and curiosity about smoking. The ESSI can identify young people who are at risk of starting to smoke cigarettes and related products. The objective of this study was to analyse the ESSI results and to examine f...

journal_title：Scientific reports

authors： Santano-Mogena E,Franco-Antonio C,Chimento-Díaz S,Rico-Martín S,Cordovilla-Guardia S

更新日期：2021-01-21 00:00:00

abstract：:Spintronic devices currently rely on magnetic switching or controlled motion of domain walls by an external magnetic field or spin-polarized current. Achieving the same degree of magnetic controllability using an electric field has potential advantages including enhanced functionality and low power consumption. Here w...

journal_title：Scientific reports

authors： Lahtinen TH,Franke KJ,van Dijken S

更新日期：2012-01-01 00:00:00

abstract：:We present here a combined theoretical and experimental investigation on effective excitation of microcantilever by using photoacoustic waves. The photoacoustic waves arose from a vibrating Al foil induced by an intensity-modulated laser. We demonstrate that, superior to photothermal excitation, this new configuration...

journal_title：Scientific reports

authors： Gao N,Zhao D,Jia R,Liu D

更新日期：2016-01-27 00:00:00

abstract：:This article presents a study whose purpose is to elucidate the damage effects in thin films on their magnetic response. Co40Fe40B20 and Ni80Fe20 films of different nanometric thicknesses were stretched by more than 10% and in situ probed by atomic force microscopy measurements to determine their irreversible mechanic...

journal_title：Scientific reports

authors： Merabtine S,Zighem F,Garcia-Sanchez A,Gunasekaran V,Belmeguenai M,Zhou X,Lupo P,Adeyeye AO,Faurie D

更新日期：2018-09-12 00:00:00

abstract：:Heart failure is the most common cause of morbidity and hospitalization in the western civilization. Protein phosphatases play a key role in the basal cardiac contractility and in the responses to β-adrenergic stimulation with type-1 phosphatase (PP-1) being major contributor. We propose here that formation of transie...

journal_title：Scientific reports

authors： Singh S,Lämmle S,Giese H,Kämmerer S,Meyer-Roxlau S,Alfar EA,Dihazi H,Guan K,El-Armouche A,Richter F

更新日期：2018-12-07 00:00:00

abstract：:Colorectal cancer (CRC) is the most common type cancers in the world. CRC occurs sporadically in the majority of cases, indicating the predominant cause of the disease are environmental factors. Diet-induced changes in gut-microbiome are recently supposed to contribute on epidemics of CRC. This study was aimed to inve...

journal_title：Scientific reports

authors： Kim DJ,Yang J,Seo H,Lee WH,Ho Lee D,Kym S,Park YS,Kim JG,Jang IJ,Kim YK,Cho JY

更新日期：2020-02-18 00:00:00

abstract：:Low Haemoglobin concentration (Hb) among women of reproductive age is a severe public health problem in sub-Saharan Africa. This study investigated the effects of putative socio-demographic factors on maternal Hb at different points of the conditional distribution of Hb concentration. We utilised quantile regression t...

journal_title：Scientific reports

authors： Amugsi DA,Dimbuene ZT,Kyobutungi C

更新日期：2020-12-07 00:00:00

abstract：:Eight advanced durum-breeding lines were treated with 5-methyl-azacytidine to test the feasibility of generating sources of Fusarium head blight (FHB) resistance. Of the 800 treated seeds, 415 germinated and were advanced up to four (M4) generations by selfing. Thirty-two of the resulting 415 M4 lines were selected fo...

journal_title：Scientific reports

authors： Kumar J,Rai KM,Pirseyedi S,Elias EM,Xu S,Dill-Macky R,Kianian SF

更新日期：2020-10-19 00:00:00

abstract：:The gut microbiome is shaped and modified by the polymorphisms of microorganisms in the intestinal tract. Its composition shows strong individual specificity and may play a crucial role in the human digestive system and metabolism. Several factors can affect the composition of the gut microbiome, such as eating habits...

journal_title：Scientific reports

authors： Chen L,Zhang YH,Huang T,Cai YD

更新日期：2016-03-15 00:00:00

abstract：:We investigated gender differences in the optic nerve head (ONH) microcirculation status in association with obstructive sleep apnea (OSA) by using laser speckle flowgraphy (LSFG). We evaluated 150 men (60.5 ± 11.0 yrs) and 45 women (63.0 ± 10.6 yrs) who underwent overnight polysomnography. The mean blur rate (MBR), m...

journal_title：Scientific reports

authors： Shiba T,Takahashi M,Matsumoto T,Hori Y

更新日期：2019-12-11 00:00:00

abstract：:Ultrasonic mating signals in moths are argued to have evolved via exploitation of the receivers' sensory bias towards bat echolocation calls. We have demonstrated that female moths of the Asian corn borer are unable to distinguish between the male courtship song and bat calls. Females react to both the male song and b...

journal_title：Scientific reports

authors： Nakano R,Takanashi T,Surlykke A,Skals N,Ishikawa Y

更新日期：2013-01-01 00:00:00

abstract：:Recently, the first-order synchronization transition has been studied in systems of coupled phase oscillators. In this paper, we propose a framework to investigate the synchronization in the frequency-weighted Kuramoto model with all-to-all couplings. A rigorous mean-field analysis is implemented to predict the possib...

journal_title：Scientific reports

authors： Xu C,Sun Y,Gao J,Qiu T,Zheng Z,Guan S

更新日期：2016-02-23 00:00:00

abstract：:We report evidence of the transition from n- to p-type conduction of InN with increasing Mg dopant concentration by using photoconductivity (PC) measurement at room temperature. This transition is depicted as a conversion from negative to positive PC under above-bandgap optical excitation. The n- to p-type transition ...

journal_title：Scientific reports

authors： Guo L,Wang XQ,Zheng XT,Yang XL,Xu FJ,Tang N,Lu LW,Ge WK,Shen B,Dmowski LH,Suski T

更新日期：2014-03-13 00:00:00

abstract：:In order to elucidate features of the denatured state ensembles that exist in equilibrium with the native state under physiological conditions, we performed 1.4-μs molecular dynamics (MD) simulations at 400 K and 450 K using the monomer subunits of three CutA1 mutants from Escherichia coli: an SH-free mutant (Ec0SH) w...

journal_title：Scientific reports

authors： Yutani K,Matsuura Y,Naitow H,Joti Y

更新日期：2018-05-16 00:00:00

abstract：:To investigate the influence of chemical weathering on CO2 consumption, an analysis was performed of water chemistry by applying water chemistry equilibria methods in the Bishuiyan subterranean basin, SW China. The average value of total ion concentrations (TZ+) was 1,854.97 μEq/L, which was significantly higher than ...

journal_title：Scientific reports

authors： Jiang P,Yu G,Zhang Q,Zou Y,Tang Q,Kang Z,Sytharith P,Xiao H

更新日期：2020-07-15 00:00:00

abstract：:Corline Heparin Conjugate (CHC), a compound of multiple unfractionated heparin chains, coats cells with a glycocalyx-like layer and may inhibit (xeno)transplant-associated activation of the plasma cascade systems. Here, we investigated the use of CHC to protect WT and genetically modified (GTKO.hCD46.hTBM) pig aortic ...

journal_title：Scientific reports

authors： Bongoni AK,Salvaris E,Nordling S,Klymiuk N,Wolf E,Ayares DL,Rieben R,Magnusson PU,Cowan PJ

更新日期：2017-06-30 00:00:00

abstract：:The endoplasmic reticulum (ER) is a multi functional organelle and plays a crucial role in protein folding and lipid biosynthesis. The SEC59 gene encodes dolichol kinase, required for protein glycosylation in the ER. The mutation of sec59-1 caused a protein N-glycosylation defect mediated ER stress resulting in increa...

journal_title：Scientific reports

authors： William James A,Ravi C,Srinivasan M,Nachiappan V

更新日期：2019-10-09 00:00:00

abstract：:The pathophysiology of diabetic nephropathy (DN) in type 2 diabetes (T2D) patients is minimally understood. We compared untargeted high-resolution accurate mass (HRAM) orbitrap-based plasma metabolomic profiles of 31 T2D-DN (with estimated glomerular filtration rate ≤80 mL/min/1.73 m2), 29 T2D and 30 normal glucose to...

journal_title：Scientific reports

authors： Devi S,Nongkhlaw B,Limesh M,Pasanna RM,Thomas T,Kuriyan R,Kurpad AV,Mukhopadhyay A

更新日期：2019-12-02 00:00:00

abstract：:Ergothioneine (ERG), a unique thiol compound, is suggested to function as an antioxidant and cytoprotectant. Despite several recent attempts to produce ERG using various organisms, its yield was still very low and the costs remained high. Since the level of ERG produced depends strictly on the availability of three di...

journal_title：Scientific reports

authors： Tanaka N,Kawano Y,Satoh Y,Dairi T,Ohtsu I

更新日期：2019-02-13 00:00:00

abstract：:AMP-activated protein kinase (AMPK) is a key sensor and regulator of glucose metabolism. Here, we demonstrated that shizukaol F, a natural compound isolated from Chloranthus japonicus, can activate AMPK and modulate glucose metabolism both in vitro and in vivo. Shizukaol F increased glucose uptake in differentiated C2...

journal_title：Scientific reports

authors： Hu R,Yan H,Fei X,Liu H,Wu J

更新日期：2017-04-10 00:00:00

abstract：:Studies in mice suggest that early life represents a critical time window, where antibiotics may exert profound and lasting effects on the gut microbiota and metabolism. We aimed to test the hypothesis that prenatal antibiotic exposure is associated with increased risk of childhood overweight in a population-based coh...

journal_title：Scientific reports

authors： Jess T,Morgen CS,Harpsøe MC,Sørensen TIA,Ajslev TA,Antvorskov JC,Allin KH

更新日期：2019-08-08 00:00:00

abstract：:Why lightning sometimes has multiple discharges to ground is an unanswered question. Recently, the observation of small plasma structures on positive leaders re-ignited the search. These small plasma structures were observed as pulsing radio sources along the positive leader length and were named "needles". Needles ma...

journal_title：Scientific reports

authors： Saba MMF,de Paiva AR,Concollato LC,Warner TA,Schumann C

更新日期：2020-10-15 00:00:00

abstract：:To explore a simple and easy-to-learn procedure for the isolation of human quiescent hepatic stellate cells (HSCs) that requires no advanced training. Thus reducing costs and increasing efficiency. This protocol will provide sufficient primary cells with minimal contaminants for future basic research on diseases assoc...

journal_title：Scientific reports

authors： Zhai X,Wang W,Dou D,Ma Y,Gang D,Jiang Z,Shi B,Jin B

更新日期：2019-09-04 00:00:00

abstract：:Prostate cancer is the most commonly diagnosed cancer in men with African American men disproportionally suffering from the burden of this disease. Biomarkers that could discriminate indolent from aggressive and drug resistance disease are lacking. MicroRNAs are small non-coding RNAs that affect numerous physiological...

journal_title：Scientific reports

authors： Cagle P,Niture S,Srivastava A,Ramalinga M,Aqeel R,Rios-Colon L,Chimeh U,Suy S,Collins SP,Dahiya R,Kumar D

更新日期：2019-07-05 00:00:00

abstract：:Electroceutical wound dressings, especially those involving current flow with silver based electrodes, show promise for treating biofilm infections. However, their mechanism of action is poorly understood. We have developed an in vitro agar based model using a bioluminescent strain of Pseudomonas aeruginosa to measure...

journal_title：Scientific reports

authors： Dusane DH,Lochab V,Jones T,Peters CW,Sindeldecker D,Das A,Roy S,Sen CK,Subramaniam VV,Wozniak DJ,Prakash S,Stoodley P

更新日期：2019-02-14 00:00:00

abstract：:Avian influenza viruses (AIV) are classified into 16 hemagglutinin (HA; H1-H16) and 9 neuraminidase (NA; N1-N9) subtypes. All AIV are low pathogenic (LP) in birds, but subtypes H5 and H7 AIV can evolve into highly pathogenic (HP) forms. In the last two decades evolution of HPAIV H7 from LPAIV has been frequently repor...

journal_title：Scientific reports

authors： Scheibner D,Ulrich R,Fatola OI,Graaf A,Gischke M,Salaheldin AH,Harder TC,Veits J,Mettenleiter TC,Abdelwhab EM

更新日期：2019-08-09 00:00:00

abstract：:We have previously shown that MicroRNA (miR) -144 is a key modulator of the acute cardioprotection associated with remote ischemic preconditioning and post myocardial infarction (MI) remodeling. In this study we examine the biology of the remodeling response after permanent ligation of the left anterior descending cor...

journal_title：Scientific reports

authors： He Q,Wang F,Honda T,James J,Li J,Redington A

更新日期：2018-11-15 00:00:00