Abstract：
:Bidirectional transplacental exchange characterizes human pregnancy. Cells exchanged between mother and fetus can durably persist as microchimerism and may have both short- and long-term consequences for the recipient. The amount, type, and persistence of microchimerism are influenced by obstetric characteristics, pregnancy complications, exposures to infection, and other factors. A reproductive-aged woman enters pregnancy harboring previously acquired microchimeric "grafts," which may influence her preconception health and her subsequent pregnancy outcomes. Many questions remain to be answered about microchimerism with broad-ranging implications. This review will summarize key aspects of this field of research and propose important questions to be addressed moving forward.
journal_name
Placentajournal_title
Placentaauthors
Gammill HS,Harrington WEdoi
10.1016/j.placenta.2017.08.071subject
Has Abstractpub_date
2017-12-01 00:00:00pages
130-133eissn
0143-4004issn
1532-3102pii
S0143-4004(17)31100-1journal_volume
60pub_type
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