当前位置： SCI文献检索 > Scientific Reports期刊下所有文献 > Oscillations of ultra-weak photon emission from cancer and non-cancer cells stressed by culture medium change and TNF-α.

Oscillations of ultra-weak photon emission from cancer and non-cancer cells stressed by culture medium change and TNF-α.

Abstract：

:Cells spontaneously emit photons in the UV to visible/near-infrared range (ultra-weak photon emission, UPE). Perturbations of the cells' state cause changes in UPE (evoked UPE). The aim of the present study was to analyze the evoked UPE dynamics of cells caused by two types of cell perturbations (stressors): (i) a cell culture medium change, and (ii) application of the pro-inflammatory cytokine tumor necrosis factor alpha (TNF-α). Four types of human cell lines were used (squamous cell carcinoma cells, A431; adenocarcinomic alveolar basal epithelial cells, A549; p53-deficient keratinocytes, HaCaT, and cervical cancer cells, HeLa). In addition to the medium change, TNF-α was applied at different concentrations (5, 10, 20, and 40 ng/mL) and UPE measurements were performed after incubation times of 0, 30, 60, 90 min, 2, 5, 12, 24, 48 h. It was observed that (i) the change of cell culture medium (without added TNF-α) induces a cell type-specific transient increase in UPE with the largest UPE increase observed in A549 cells, (ii) the addition of TNF-α induces a cell type-specific and dose-dependent change in UPE, and (iii) stressed cell cultures in general exhibit oscillatory UPE changes.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Madl P,Verwanger T,Geppert M,Scholkmann F

doi

10.1038/s41598-017-10949-z

subject

Has Abstract

pub_date

2017-09-12 00:00:00

pages

11249

issue

1

issn

2045-2322

pii

10.1038/s41598-017-10949-z

journal_volume

7

pub_type

杂志文章

相关文献

Scientific Reports文献大全
  • Mechanized transplanting with side deep fertilization increases yield and nitrogen use efficiency of rice in Eastern China.

    abstract：:The application of nitrogen (N) fertilizer deep in soil at the same time as mechanical transplanting of rice seedlings is an effective alternative to conventional broadcasting of fertilizer, but its effects on yields and profitability have not been analysed in detail. Here, we analysed the effects of a side deep appli...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-42039-7

    authors： Zhu C,Xiang J,Zhang Y,Zhang Y,Zhu D,Chen H

    更新日期：2019-04-04 00:00:00

  • Effect of caloric restriction on gut permeability, inflammation markers, and fecal microbiota in obese women.

    abstract：:Recent findings suggest an association between obesity, loss of gut barrier function and changes in microbiota profiles. Our primary objective was to examine the effect of caloric restriction and subsequent weight reduction on gut permeability in obese women. The impact on inflammatory markers and fecal microbiota was...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-12109-9

    authors： Ott B,Skurk T,Hastreiter L,Lagkouvardos I,Fischer S,Büttner J,Kellerer T,Clavel T,Rychlik M,Haller D,Hauner H

    更新日期：2017-09-20 00:00:00

  • Characterization of Discrete Phosphopantetheinyl Transferases in Streptomyces tsukubaensis L19 Unveils a Complicate Phosphopantetheinylation Network.

    abstract：:Phosphopantetheinyl transferases (PPTases) play essential roles in both primary metabolisms and secondary metabolisms via post-translational modification of acyl carrier proteins (ACPs) and peptidyl carrier proteins (PCPs). In this study, an industrial FK506 producing strain Streptomyces tsukubaensis L19, together wit...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep24255

    authors： Wang YY,Zhang XS,Luo HD,Ren NN,Jiang XH,Jiang H,Li YQ

    更新日期：2016-04-07 00:00:00

  • Metabolic output defines Escherichia coli as a health-promoting microbe against intestinal Pseudomonas aeruginosa.

    abstract：:Gut microbiota acts as a barrier against intestinal pathogens, but species-specific protection of the host from infection remains relatively unexplored. Although lactobacilli and bifidobacteria produce beneficial lactic and short-chain fatty acids in the mammalian gut, the significance of intestinal Escherichia coli p...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-51058-3

    authors： Christofi T,Panayidou S,Dieronitou I,Michael C,Apidianakis Y

    更新日期：2019-10-08 00:00:00

  • Multiple genotypes of Echovirus 11 circulated in mainland China between 1994 and 2017.

    abstract：:Echovirus 11 (E-11) is one of the most frequently isolated enteroviruses causing meningitis and other diseases such as hand, foot, and mouth disease (HFMD) and acute flaccid paralysis (AFP). Fifty-nine newly determined E-11 VP1 sequences from the China AFP and HFMD surveillance network and 500 E-11 VP1 sequences obtai...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-46870-w

    authors： Li J,Yan D,Chen L,Zhang Y,Song Y,Zhu S,Ji T,Zhou W,Gan F,Wang X,Hong M,Guan L,Shi Y,Wu G,Xu W

    更新日期：2019-07-22 00:00:00

  • Experimental study of the nonreciprocal effective interactions between microparticles in an anisotropic plasma.

    abstract：:There is a variety of cases in nature when the action-reaction symmetry is broken. In particular, suitable conditions for this are realized in colloidal suspensions and complex plasmas. Since the first theories and simulations of the nonreciprocal effective interactions between microparticles in complex plasmas were p...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-70441-z

    authors： Lisin EA,Petrov OF,Sametov EA,Vaulina OS,Statsenko KB,Vasiliev MM,Carmona-Reyes J,Hyde TW

    更新日期：2020-08-12 00:00:00

  • Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk.

    abstract：:The cannabinoid type 1 (CB1) receptor and the capsaicin receptor (TRPV1) exhibit co-expression and complex, but largely unknown, functional interactions in a sub-population of primary sensory neurons (PSN). We report that PSN co-expressing CB1 receptor and TRPV1 form two distinct sub-populations based on their pharmac...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep33307

    authors： Chen J,Varga A,Selvarajah S,Jenes A,Dienes B,Sousa-Valente J,Kulik A,Veress G,Brain SD,Baker D,Urban L,Mackie K,Nagy I

    更新日期：2016-09-22 00:00:00

  • The foundress's dilemma: group selection for cooperation among queens of the harvester ant, Pogonomyrmex californicus.

    abstract：:The evolution of cooperation is a fundamental problem in biology, especially for non-relatives, where indirect fitness benefits cannot counter within-group inequalities. Multilevel selection models show how cooperation can evolve if it generates a group-level advantage, even when cooperators are disadvantaged within t...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep29828

    authors： Shaffer Z,Sasaki T,Haney B,Janssen M,Pratt SC,Fewell JH

    更新日期：2016-07-28 00:00:00

  • Functions of miR-146a and miR-222 in Tumor-associated Macrophages in Breast Cancer.

    abstract：:Tumor-associated macrophages (TAMs) play critical roles in promoting tumor progression and invasion. However, the molecular mechanisms underlying TAM regulation remain to be further investigated and may make significant contributions to cancer treatment. Mammalian microRNAs (miRNAs) have recently been identified as im...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep18648

    authors： Li Y,Zhao L,Shi B,Ma S,Xu Z,Ge Y,Liu Y,Zheng D,Shi J

    更新日期：2015-12-22 00:00:00

  • Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation.

    abstract：:Multimodal polymeric nanoparticles have many exciting diagnostic and therapeutic applications, yet their uptake and passage by the placenta, and applications in the treatment of pregnancy complications have not been thoroughly investigated. In this work, the maternal-fetal-placental biodistribution of anionic and cati...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-03128-7

    authors： Ho D,Leong JW,Crew RC,Norret M,House MJ,Mark PJ,Waddell BJ,Iyer KS,Keelan JA

    更新日期：2017-06-06 00:00:00

  • Determination of total and unbound docetaxel in plasma by ultrafiltration and UPLC-MS/MS: application to pharmacokinetic studies.

    abstract：:A sensitive and specific liquid chromatographic/tandem mass spectrometric (LC-MS/MS) method was developed and validated for quantifying total and unbound docetaxel drug concentrations in plasma. Calibration curves for unbound and total docetaxel were linear over the respective ranges of 0.108~10.8 and 0.54~216 ng/mL. ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-15176-0

    authors： Sheu MT,Wu CY,Su CY,Ho HO

    更新日期：2017-11-06 00:00:00

  • Mitogenomics of historical type specimens of Australasian turtles: clarification of taxonomic confusion and old mitochondrial introgression.

    abstract：:Diagnosability is central to taxonomy as are type specimens which define taxa. New advances in technologies and the discovery of new informative traits must be matched with previous taxonomic decisions based on name-bearing type specimens. Consequently, the challenge of sequencing highly degraded DNA from historical t...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-42310-x

    authors： Kehlmaier C,Zhang X,Georges A,Campbell PD,Thomson S,Fritz U

    更新日期：2019-04-09 00:00:00

  • Active dynamics of colloidal particles in time-varying laser speckle patterns.

    abstract：:Colloidal particles immersed in a dynamic speckle pattern experience an optical force that fluctuates both in space and time. The resulting dynamics presents many interesting analogies with a broad class of non-equilibrium systems like: active colloids, self propelled microorganisms, transport in dynamical intracellul...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep27681

    authors： Bianchi S,Pruner R,Vizsnyiczai G,Maggi C,Di Leonardo R

    更新日期：2016-06-09 00:00:00

  • Large-scale identification of human protein function using topological features of interaction network.

    abstract：:The annotation of protein function is a vital step to elucidate the essence of life at a molecular level, and it is also meritorious in biomedical and pharmaceutical industry. Developments of sequencing technology result in constant expansion of the gap between the number of the known sequences and their functions. Th...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep37179

    authors： Li Z,Liu Z,Zhong W,Huang M,Wu N,Xie Y,Dai Z,Zou X

    更新日期：2016-11-16 00:00:00

  • Radiomics prognostication model in glioblastoma using diffusion- and perfusion-weighted MRI.

    abstract：:We aimed to develop and validate a multiparametric MR radiomics model using conventional, diffusion-, and perfusion-weighted MR imaging for better prognostication in patients with newly diagnosed glioblastoma. A total of 216 patients with newly diagnosed glioblastoma were enrolled from two tertiary medical centers and...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-61178-w

    authors： Park JE,Kim HS,Jo Y,Yoo RE,Choi SH,Nam SJ,Kim JH

    更新日期：2020-03-06 00:00:00

  • Phylogenetic analyses and in-seedling expression of ammonium and nitrate transporters in wheat.

    abstract：:Plants deploy several ammonium transporter (AMT) and nitrate transporter (NRT) genes to acquire NH4+ and NO3- from the soil into the roots and then transport them to other plant organs. Coding sequences of wheat genes obtained from ENSEMBL were aligned to known AMT and NRT sequences of Arabidopsis, barley, maize, rice...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-25430-8

    authors： Bajgain P,Russell B,Mohammadi M

    更新日期：2018-05-04 00:00:00

  • Spontaneous Isopeptide Bond Formation as a Powerful Tool for Engineering Site-Specific Antibody-Drug Conjugates.

    abstract：:Spontaneous isopeptide bond formation, a stabilizing posttranslational modification that can be found in gram-positive bacterial cell surface proteins, has previously been used to develop a peptide-peptide ligation technology that enables the polymerization of tagged-proteins catalyzed by SpyLigase. Here we adapted th...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep39291

    authors： Siegmund V,Piater B,Zakeri B,Eichhorn T,Fischer F,Deutsch C,Becker S,Toleikis L,Hock B,Betz UA,Kolmar H

    更新日期：2016-12-16 00:00:00

  • Identification of a novel family of carbohydrate-binding modules with broad ligand specificity.

    abstract：:Most enzymes that act on carbohydrates include non-catalytic carbohydrate-binding modules (CBMs) that recognize and target carbohydrates. CBMs bring their appended catalytic modules into close proximity with the target substrate and increase the hydrolytic rate of enzymes acting on insoluble substrates. We previously ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep19392

    authors： Duan CJ,Feng YL,Cao QL,Huang MY,Feng JX

    更新日期：2016-01-14 00:00:00

  • BMP6 Regulates Proliferation and Apoptosis of Human Sertoli Cells Via Smad2/3 and Cyclin D1 Pathway and DACH1 and TFAP2A Activation.

    abstract：:Sertoli cells are essential for regulating normal spermatogenesis. However, the mechanisms underlying human Sertoli cell development remain largely elusive. Here we examined the function and signaling pathways of BMP6 in regulating human Sertoli cells. RT-PCR, immunocytochemistry and Western blots revealed that BMP6 a...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep45298

    authors： Wang H,Yuan Q,Sun M,Niu M,Wen L,Fu H,Zhou F,Chen Z,Yao C,Hou J,Shen R,Lin Q,Liu W,Jia R,Li Z,He Z

    更新日期：2017-04-07 00:00:00

  • Live imaging of alterations in cellular morphology and organelles during cornification using an epidermal equivalent model.

    abstract：:The stratum corneum plays a crucial role in epidermal barrier function. Various changes occur in granular cells at the uppermost stratum granulosum during cornification. To understand the temporal details of this process, we visualized the cell shape and organelles of cornifying keratinocytes in a living human epiderm...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-62240-3

    authors： Ipponjima S,Umino Y,Nagayama M,Denda M

    更新日期：2020-03-26 00:00:00

  • Interocular contrast difference drives illusory 3D percept.

    abstract：:Any processing delay between the two eyes can result in illusory 3D percepts for moving objects because of either changes in the pure disparities over time for disparity sensors or by changes to sensors that encode motion/disparity conjointly. This is demonstrated by viewing a fronto-parallel pendulum through a neutra...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-06151-w

    authors： Reynaud A,Hess RF

    更新日期：2017-07-17 00:00:00

  • Identification of DKK-1 as a novel mediator of statin effects in human endothelial cells.

    abstract：:This study shows that DKK-1, a member of the Dickkopf family and a regulator of the Wnt pathways, represents a novel target of statins which, through the inhibition of HMG-CoA reductase and of non-steroidal isoprenoid intermediates, exert extra-beneficial effect in preventing atherosclerosis beyond their effect on the...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-35119-7

    authors： Pontremoli M,Brioschi M,Baetta R,Ghilardi S,Banfi C

    更新日期：2018-11-12 00:00:00

  • Confinement Effect on Porosity and Permeability of Shales.

    abstract：:Porosity and permeability are the key factors in assessing the hydrocarbon productivity of unconventional (shale) reservoirs, which are complex in nature due to their heterogeneous mineralogy and poorly connected nano- and micro-pore systems. Experimental efforts to measure these petrophysical properties posse many li...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-56885-y

    authors： Goral J,Panja P,Deo M,Andrew M,Linden S,Schwarz JO,Wiegmann A

    更新日期：2020-01-08 00:00:00

  • Controlling and modelling the wetting properties of III-V semiconductor surfaces using re-entrant nanostructures.

    abstract：:Inorganic semiconductors such as III-V materials are very important in our everyday life as they are used for manufacturing optoelectronic and microelectronic components with important applications span from energy harvesting to telecommunications. In some applications, these components are required to operate in hars...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-21864-2

    authors： Ng WH,Lu Y,Liu H,Carmalt CJ,Parkin IP,Kenyon AJ

    更新日期：2018-02-23 00:00:00

  • Distinct epigenetic signatures between adult-onset and late-onset depression.

    abstract：:The heterogeneity of major depressive disorder (MDD) is attributed to the fact that diagnostic criteria (e.g., DSM-5) are only based on clinical symptoms. The discovery of blood biomarkers has the potential to change the diagnosis of MDD. The purpose of this study was to identify blood biomarkers of DNA methylation by...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-021-81758-8

    authors： Yamagata H,Ogihara H,Matsuo K,Uchida S,Kobayashi A,Seki T,Kobayashi M,Harada K,Chen C,Miyata S,Fukuda M,Mikuni M,Hamamoto Y,Watanabe Y,Nakagawa S

    更新日期：2021-01-27 00:00:00

  • Climate variability and outbreaks of infectious diseases in Europe.

    abstract：:Several studies provide evidence of a link between vector-borne disease outbreaks and El Niño driven climate anomalies. Less investigated are the effects of the North Atlantic Oscillation (NAO). Here, we test its impact on outbreak occurrences of 13 infectious diseases over Europe during the last fifty years, controll...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep01774

    authors： Morand S,Owers KA,Waret-Szkuta A,McIntyre KM,Baylis M

    更新日期：2013-01-01 00:00:00

  • A rightward saccade to an unexpected stimulus as a marker for lateralised visuospatial attention.

    abstract：:The human brain is lateralised to the right for visuospatial attention, particularly when reorienting attention to unexpected stimuli. However, the developmental characteristics of lateralisation remain unclear. To address this question, we devised a saccade task applicable for both adults and children. To assess the ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-25890-y

    authors： Sanefuji M,Yamashita H,Torio M,Katsuki D,Akamine S,Ishizaki Y,Kishimoto J,Sakai Y,Takada H,Yoshida K,Ohga S

    更新日期：2018-05-15 00:00:00

  • Supramolecular polymerization of a prebiotic nucleoside provides insights into the creation of sequence-controlled polymers.

    abstract：:Self-assembly of a nucleoside on Au(111) was studied to ascertain whether polymerization on well-defined substrates constitutes a promising approach for making sequence-controlled polymers. Scanning tunneling microscopy and density functional theory were used to investigate the self-assembly on Au(111) of (RS)-N(9)-(2...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep18891

    authors： Wang J,Bonnesen PV,Rangel E,Vallejo E,Sanchez-Castillo A,James Cleaves Ii H,Baddorf AP,Sumpter BG,Pan M,Maksymovych P,Fuentes-Cabrera M

    更新日期：2016-01-04 00:00:00

  • Rational engineering of a virulence gene from Mycobacterium tuberculosis facilitates proteomic analysis of a natural protein N-terminus.

    abstract：:Mass spectrometry (MS) for the detection of proteins is an indispensable tool for evaluating the biological processes of the proteome. Proteomics frequently requires proteolysis of proteins into peptide fragments. Proteins can be refractory to ideal proteolysis at the sequence level rendering them difficult to analyze...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep33265

    authors： Reyna C,Mba Medie F,Champion MM,Champion PA

    更新日期：2016-09-14 00:00:00

  • Detection of inflammatory cell function using (13)C magnetic resonance spectroscopy of hyperpolarized [6-(13)C]-arginine.

    abstract：:Myeloid-derived suppressor cells (MDSCs) are highly prevalent inflammatory cells that play a key role in tumor development and are considered therapeutic targets. MDSCs promote tumor growth by blocking T-cell-mediated anti-tumoral immune response through depletion of arginine that is essential for T-cell proliferation...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep31397

    authors： Najac C,Chaumeil MM,Kohanbash G,Guglielmetti C,Gordon JW,Okada H,Ronen SM

    更新日期：2016-08-10 00:00:00