Abstract:
:We established a chronic dacryocystitis model by injecting of 0.05, 0.1, and 0.15 ml self-curing resin via the lacrimal punctum in rabbits. Animals were randomized into four groups (n = 11 animals/group). The control group received 0.15 ml normal saline. Within three months postinjection, epiphora and eye discharge were observed. At the 90th day postlacrimal passage irrigation, CT dacryocystography was performed to find changes in the lacrimal image, and hematoxylin and eosin staining was made to identify pathological changes of the lacrimal sac. Three months postinjection, the rabbits in control group and those who received 0.05 and 0.1 ml self-curing resin failed to develop chronic dacryocystitis. However, 8/11 (72.7%) rabbits those received 0.15 ml self-curing resin were symptomatic and showed complete reflux in lacrimal passage irrigation, indicating the obstruction of the nasolacrimal duct. CT dacryocystography showed that the obstruction was present only in the animals with chronic dacryocystitis. Pathological examinations of chronic dacryocystitis also revealed significantly inflammatory changes, such as mucus epithelium thickening, irregular papillary proliferation, and submucosal fibrous deposition. Local injection of 0.15 ml self-curing resin can induce permanent obstruction of the nasolacrimal duct in rabbits and establish a model of chronic dacryocystitis.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Hou K,Ai T,Liu R,Xiang N,Jin J,Hu W,Luo Bdoi
10.1155/2017/3438041subject
Has Abstractpub_date
2017-01-01 00:00:00pages
3438041eissn
2090-004Xissn
2090-0058journal_volume
2017pub_type
杂志文章abstract::Purpose. To report a comparative prospective long-term functional analysis after Riboflavin UV A corneal cross-linking (CXL) in three different age groups of patients affected by progressive keratoconus (KC). Methods. Functional analysis comprised paediatric patients (≤18 years) included 152 eyes (29.5%); intermediate...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/608041
更新日期:2011-01-01 00:00:00
abstract:Purpose:To analyze the "in vitro" aberrometric pattern of a refractive IOL and two extended depth of focus IOLs. Methods:A special optical bench with a Shack-Hartmann wavefront sensor (SH) was designed for the measurement. Three presbyopia correction IOLs were analyzed: Mini WELL (MW), TECNIS Symfony ZXR00 (SYM), and ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/7095734
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To evaluate the effect of the Rho-kinase inhibitor Y-27632 on postoperative inflammation and adhesion following extraocular muscle surgery in rabbits. METHODS:The superior rectus muscle reinsertion was performed on both eyes of 8 New Zealand white rabbits. After reinsertion, the rabbits received subconjunctiva...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/8653130
更新日期:2017-01-01 00:00:00
abstract::Purpose. To evaluate the neutrophil/lymphocyte ratio (NLR) and the platelet/lymphocyte ratio(PLR) value in the development of branch retinal vein occlusion (BRVO)patients. METHODS:81 patients with BRVO and 81 age and sex-matched subjects were recruited as the control group. The BRVO diagnosis was confirmed under comp...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/6043612
更新日期:2019-10-31 00:00:00
abstract::Glaucoma is one of the leading causes of blindness worldwide. Recent studies suggest that intraocular pressure (IOP) fluctuations, peaks, and rhythm are important factors in disease advancement. Yet, current glaucoma management remains hinged on single IOP measurements during clinic hours. To overcome this limitation,...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2016/4727423
更新日期:2016-01-01 00:00:00
abstract:Purpose:To investigate the association between regional solar radiation and myopia occurrence in South Korean children. Materials and Methods:A population-based cross-sectional study using data of 1218 children aged 7-9 years from the Korea National Health and Nutritional Examination Survey was conducted from January ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/7643850
更新日期:2019-06-10 00:00:00
abstract::Purpose. To evaluate the outcome of combined vitrectomy with phacoemulsification without postoperative face-down positioning for idiopathic macular holes (MHs). Design. Retrospective, observational case series. Participants. Forty-two eyes of 42 patients with MH. Methods. We studied 42 eyes of 42 cases followed up for...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/571748
更新日期:2012-01-01 00:00:00
abstract:Background:To evaluate the outcome and complications of transscleral suture-fixated posterior chamber intraocular lens (PCIOL) implantation combined with Ahmed glaucoma valve (AGV) surgery in Asian eyes. Design:This was a retrospective study that included 22 eyes from 22 participants. The surgeries were performed at S...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/9824035
更新日期:2018-03-25 00:00:00
abstract:Purpose:To assess the effect of age on elevation and pachymetric Pentacam keratoconus (KC) detection indices, and the need to adjust normative values accordingly. Methods:In a retrospective study, 95 eyes of myopic normal subjects without KC were evaluated using the OCULUS Pentacam, with an age range of 17.4 to 46.8 y...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/2016564
更新日期:2018-04-22 00:00:00
abstract::Purpose. To compare the clinical features of community-associated (CA) and healthcare-associated (HA) methicillin-resistant Staphylococcus aureus (MRSA) keratitis. Methods. Patients presenting with culture-proven MRSA keratitis between January 1, 2006, and December 31, 2010, at Chang Gung Memorial Hospital, Taiwan, we...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/923941
更新日期:2015-01-01 00:00:00
abstract::Purpose. To investigate the thickness of the retinal nerve fiber layer (RNFL) and choroid in patients who have migraines in comparison to healthy controls. Methods. This study included 76 eyes and patients in the migraine group, 36 with aura (MWA group) and 40 without (MWoA group), and 38 eyes as control subjects. The...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/868967
更新日期:2015-01-01 00:00:00
abstract::SD-OCT has become an essential tool for evaluating macular pathology; however several aspects of data collection and analysis affect the accuracy of retinal thickness measurements. Here we evaluated sampling density, scan centering, and axial length compensation as factors affecting the accuracy of macular thickness m...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/692574
更新日期:2011-01-01 00:00:00
abstract:Background:For so long, corneal diseases have been known as one of the leading causes to blindness in the global. This blindness might be due to failure to accept the corneal transplantation. Therefore, this study aimed to determine the prevalence and the root challenges for corneal transplantation acceptance at the Un...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/4560649
更新日期:2019-12-13 00:00:00
abstract::Diabetic retinal complications, including macular edema (DME) and proliferative diabetic retinopathy (PDR), are the leading cause of new cases of blindness among adults aged 20-74. Chronic hyperglycemia, considered the underlying cause of diabetic retinopathy, is thought to act first through violation of the pericyte-...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/209538
更新日期:2012-01-01 00:00:00
abstract::Purpose. To evaluate the anterior chamber volume in cataract patients with Swept-Source Optical Coherence Tomography (SS-OCT) and its influencing factors. Methods. Anterior chamber volume of 92 cataract patients was evaluated with SS-OCT in this cross-sectional study. Univariate analyses and multiple linear regression...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/8656301
更新日期:2016-01-01 00:00:00
abstract::Purpose. To evaluate the effectiveness and safety of perfluorohexyloctane (F6H8) for intraoperative flattening of the retina and of F6H8/silicone oil (SO) 1000 cSt as a postoperative tamponade for inferior retinal detachment with inferior proliferative vitreoretinopathy. Methods. This is a retrospective review of 22 p...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/956831
更新日期:2014-01-01 00:00:00
abstract::Macular pseudoholes (MPHs) and lamellar macular holes (LMHs) have been recently defined according to spectral domain optical coherence tomography (SD-OCT) criteria. A major feature for differentiating an MPH from an LMH remains the loss of foveal tissue. The anatomy of the foveola is peculiar with the macular pigment ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2019/4948212
更新日期:2019-02-10 00:00:00
abstract:Purpose:Visual loss is a devastating perioperative complication that can result from elevated intraocular pressure (IOP). The Trendelenburg position during surgery increases IOP. The purpose of this study was to quantify IOP changes in patients undergoing laparoscopic hysterectomy, at different time points and body pos...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/1457851
更新日期:2018-03-15 00:00:00
abstract::Background. The aim of this study is to investigate the ocular thermographic profiles in age-related macular degeneration (AMD) eyes and age-matched controls to detect possible hemodynamic abnormalities, which could be involved in the pathogenesis of the disease. Methods. 32 eyes with early AMD, 37 eyes with atrophic ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/281010
更新日期:2014-01-01 00:00:00
abstract:Objective:This study aims to describe the clinical manifestations and outcomes in a cohort of older Chinese patients. Method:A retrospective study of patients aged ≥ 45 years who had a first episode of optic neuritis (ON) between May 2008 and November 2012. Clinical features at onset and last follow-up were analyzed w...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/3458356
更新日期:2017-01-01 00:00:00
abstract::Keratoconus is typically diagnosed through changes at the anterior ocular surface. However, we wished to assess if macular parameter changes might also occur in these patients. We assessed posterior changes through the use of optical coherence tomography and compared to a nonkeratoconus patient group. All subjects und...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/245953
更新日期:2015-01-01 00:00:00
abstract:Purpose:The objective of this study was to evaluate the microbiological spectrum and antibiotic susceptibilities of isolates in posttraumatic endophthalmitis over a 15-year period. Methods:A retrospective study of 3,163 posttraumatic endophthalmitis cases was conducted between July 2004 and July 2019. The outcome meas...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/5053923
更新日期:2020-04-29 00:00:00
abstract:PURPOSE:To investigate neovascular age-related macular degeneration (AMD) in patients aged ≥90 years from several perspectives for a comprehensive overview: prevalence, presenting characteristics, treatment adherence, reasons for discontinuation, and efficacy of antivascular endothelial growth factor (VEGF) treatment c...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/7194927
更新日期:2017-01-01 00:00:00
abstract:Purpose:To examine the current knowledge about the age-related processes in the anterior segment of the eye at a biological, clinical, and molecular level. Methods:We reviewed the available published literature that addresses the aging process of the anterior segment of the eye and its associated molecular and physiol...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2017/1295132
更新日期:2017-01-01 00:00:00
abstract::Objective. To describe the clinicoradiological and histopathological findings in a case of lacrimal gland enlargement secondary to lymphomatoid granulomatosis (LG) and to review the literature. Design. Case report and systematic literature review. Methods. A 75-year-old woman presented with right ptosis. Computerised ...
journal_title:Journal of ophthalmology
pub_type:
doi:10.1155/2010/358121
更新日期:2010-01-01 00:00:00
abstract::Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. The objective of this study is to investigate the effects of vascular endothelial growth factor receptor 1 (VEGFR1) blockade on the complications of DR. Experimental models of diabetes were induced with streptozotocin (STZ) treatment or I...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/605946
更新日期:2015-01-01 00:00:00
abstract:Purpose:To evaluate early changes in visual function and visual quality parameters after Descemet membrane endothelial keratoplasty (DMEK) and to compare the outcomes with healthy controls. Methods:Thirteen patients who underwent DMEK and 14 controls were evaluated. All subjects underwent visual function evaluation, i...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/2012560
更新日期:2018-09-23 00:00:00
abstract:Purpose:Although optical coherence tomography (OCT) is essential for ophthalmologists, reading of findings requires expertise. The purpose of this study is to test deep learning with image augmentation for automated detection of chorioretinal diseases. Methods:A retina specialist diagnosed 1,200 OCT images. The diagno...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/6319581
更新日期:2019-04-09 00:00:00
abstract:AIM:To discuss the clinical characteristics of immune-related dry eye. METHODS:Simple dry eye (SDE) group: we selected 224 patients of simple dry eye with no systemic lesions. Immune-related dry eye (IRDE) group: we selected 207 patients of dry eye complicated with immune system diseases, including 70 cases of Sjögren...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/8532397
更新日期:2017-01-01 00:00:00
abstract:Background:The aim of this meta-analysis was to compare morphological and functional outcomes between vitrectomy with the inverted internal limiting membrane (ILM) flap technique and vitrectomy with internal limiting membrane peeling in highly myopic eyes with macular hole- (MH-) induced retinal detachment (MHRD). Met...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2020/2374650
更新日期:2020-08-24 00:00:00