Fundus Autofluorescence in Lamellar Macular Holes and Pseudoholes: A Review.

Abstract:

:Macular pseudoholes (MPHs) and lamellar macular holes (LMHs) have been recently defined according to spectral domain optical coherence tomography (SD-OCT) criteria. A major feature for differentiating an MPH from an LMH remains the loss of foveal tissue. The anatomy of the foveola is peculiar with the macular pigment (MP) embedded in a very thin layer of tissue underlying the internal limiting membrane and mainly constituted of a specialized group of Müller cells and Henle's fibers. Despite the near microscopic resolution (≈5-7 μm) and the capability to visualize the outer retina in detail, SD-OCT may fail to ascertain whether a very small loss of this foveolar tissue has occurred. Blue-fundus autofluorescence (B-FAF) imaging is useful in this respect because even very small loss of MP can be identified, suggesting a corresponding localized loss of the innermost layers of the foveola. A definition of MP loss would help differentiating an LMH from an MPH where B-FAF imaging will be negative.

journal_name

J Ophthalmol

journal_title

Journal of ophthalmology

authors

Bottoni F

doi

10.1155/2019/4948212

subject

Has Abstract

pub_date

2019-02-10 00:00:00

pages

4948212

eissn

2090-004X

issn

2090-0058

journal_volume

2019

pub_type

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