Abstract：
:Purpose. This study investigated the effects of oral propolis on the progression of galactose-induced sugar cataracts in rats and the in vitro effects of propolis on high-glucose-induced reactive oxygen species (ROS) and cell death in cultured rat lens cells (RLECs). Methods. Galactose-fed rats and RLECs cultured in high glucose (55 mM) medium were treated with propolis or vehicle control. Relative lens opacity was assessed by densitometry and changes in lens morphology by histochemical analysis. Intracellular ROS levels and cell viability were measured. Results. Oral administration of propolis significantly inhibited the onset and progression of cataract in 15% and 25% of galactose-fed rats, respectively. RLECs cultured with high glucose showed a significant increase in ROS expression with reduced cell viability. Treatment of these RLECs with 5 and 50 μg/mL propolis cultured significantly reduced ROS levels and increased cell viability, indicating that the antioxidant activity of propolis protected cells against ROS-induced damage. Conclusion. Propolis significantly inhibited the onset and progression of sugar cataract in rats and mitigated high-glucose-induced ROS production and cell death. These effects may be associated with the ability of propolis to inhibit hyperglycemia-evoked oxidative or osmotic stress-induced cellular insults.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Shibata T,Shibata S,Shibata N,Kiyokawa E,Sasaki H,Singh DP,Kubo Edoi
10.1155/2016/1917093subject
Has Abstractpub_date
2016-01-01 00:00:00pages
1917093eissn
2090-004Xissn
2090-0058journal_volume
2016pub_type
杂志文章abstract：Purpose:To evaluate the difference in the repeatability of automated superficial retinal vessel density and foveal avascular zone (FAZ) metrics according to the measurement area of optical coherence tomography angiography (OCTA). Methods:A total of 127 normal eyes from 127 healthy subjects were included. Macular angio...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/5686894
更新日期：2020-04-17 00:00:00
abstract：:Purpose. To investigate the agreement between morphometric optic nerve head parameters assessed with the confocal laser ophthalmoscope HRT III and the stereoscopic fundus camera Kowa nonmyd WX3D retrospectively. Methods. Morphometric optic nerve head parameters of 40 eyes of 40 patients with primary open angle glaucom...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/4764857
更新日期：2016-01-01 00:00:00
abstract：Purpose:Although optical coherence tomography (OCT) is essential for ophthalmologists, reading of findings requires expertise. The purpose of this study is to test deep learning with image augmentation for automated detection of chorioretinal diseases. Methods:A retina specialist diagnosed 1,200 OCT images. The diagno...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/6319581
更新日期：2019-04-09 00:00:00
abstract：:The leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4, also called GPR48) plays a key role in multiple developmental processes, and mice lacking Lgr4 display anterior segment dysgenesis leading to early-onset glaucomatous retinal ganglion cell loss as well as defective eyelid formation. This paper will...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2013/987494
更新日期：2013-01-01 00:00:00
abstract：Purpose:To investigate whether the risk of subsequent stroke, ischemic stroke, hemorrhagic stroke, and all-cause mortality is increased among retinal vein occlusion (RVO) patients compared to non-RVO patients. Methods:From the entire population of the Taiwan National Health Insurance Research Database (NHIRD) from 200...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/8629429
更新日期：2018-09-09 00:00:00
abstract：:Current intraocular pressure (IOP) measurement using air puff could be erroneous without applying proper corrections. Although noncontact tonometry is not considered to be accurate, it is still popularly used by eye clinics. It is thus necessary to extract the correct information from their results. This study propose...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/5410143
更新日期：2017-01-01 00:00:00
abstract：:The costs for glaucoma care are rising worldwide. The main reason is the increase of life expectancy and the increasing variety of diagnostic tests and therapeutically options by implants and devices. How can we influence the increase in costs? Does a relationship exist between the rising costs and the behavior of pat...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2020/5901537
更新日期：2020-04-08 00:00:00
abstract：Purpose:The purpose of this meta-analysis was to assess the percent reduction in the intraocular pressure (IOP) after argon laser peripheral iridoplasty (ALPI) and systemic medical therapy in patients with acute primary angle closure (APAC). Methods:We searched a number of electronic databases, including MEDLINE, EMBA...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2019/7697416
更新日期：2019-05-02 00:00:00
abstract：:Aim. To examine subscale and total scores of NEI-VFQ questionnaire of type 2 diabetes patients at different diabetic retinopathy (DRP) stages. Methods. A total number of 201 patients have been included. Prior to ophthalmological examination all patients participated in the NEI-VFQ questionnaire. The patients were divi...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/1549318
更新日期：2016-01-01 00:00:00
abstract：:Aim. The aim of this study was to determine the intra- and interobserver variability of two Scheimpflug based camera systems, Pentacam and Sirius. In addition, the comparability of the measurements was tested in healthy subjects, subjects with regular astigmatism, and keratoconus patients. Methods. Intra- and interobs...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/315281
更新日期：2015-01-01 00:00:00
abstract：:Purpose. This study retrospectively analyzed cataract surgeries to examine the usefulness of Surgical Media Center (SMC) (Abbott Medical Optics Inc.), a new cataract surgery recording device, for training of cataract surgery. Methods. We studied five hundred cataract surgeries conducted with a phacoemulsification syst...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/8435086
更新日期：2016-01-01 00:00:00
abstract：:Retinitis pigmentosa (RP) represents a clinically and genetically heterogeneous disease characterized by progressive photoreceptor loss. In recent years, research has been rarely made in blood flow affected in RP. The specific mechanism of blood flow affected in RP is not completely clear. A number of studies indicate...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2018/3249064
更新日期：2018-02-25 00:00:00
abstract：:Age-related macular degeneration (AMD) is a major cause of blindness worldwide. Oxidative stress plays a large role in the pathogenesis of AMD. The present study was to evaluate the effects of Fructus lycii ethanol extract on AMD in mice and to investigate whether combination of lutein and zeaxanthin, two carotenoid p...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2013/862806
更新日期：2013-01-01 00:00:00
abstract：:Purpose. To examine financial and clinical work productivity outcomes associated with the use of the electronic health record (EHR). Methods. 191,360 billable clinical encounters were analyzed for 12 clinical providers over a 9-year study period during which an EHR was implemented. Main outcome measures were clinical ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/329819
更新日期：2015-01-01 00:00:00
abstract：:Purpose. Randomized controlled trial aimed at comparing surgical outcomes in a group of patients suffering from hyperfunction of the inferior oblique (IO) muscle with abnormal head position (AHP). The surgical techniques being compared are Recession and (thread) Controlled Myotomy. Materials and Methods. The group of ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/1725484
更新日期：2016-01-01 00:00:00
abstract：:Purpose. To evaluate the effectiveness of deep sclerectomy with T-flux implant (DS T-flux) in patients with pseudoexfoliation glaucoma (PExG). Methods. 20 eyes of 18 patients with medically uncontrolled PExG have undergone DS T-flux implantation. Postoperatively we evaluated the IOP values and the frequency of complic...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/6923208
更新日期：2017-01-01 00:00:00
abstract：:Primary congenital glaucoma is a worldwide diagnostic and therapeutic challenge. Although medical management is often a temporizing measure, early surgical intervention is the definitive treatment. As the abundance of surgical treatment options continues to expand, the authors will compare and contrast the available o...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2013/612708
更新日期：2013-01-01 00:00:00
abstract：Purpose:Evaluation of the indications, anatomical and functional results, and complications of total penetrating keratoplasty (TPK) in disorders involving whole cornea. Materials and Methods:We analyzed outcomes of the surgical treatment of 47 eyes of 46 patients that underwent TPK. Indications were infectious keratit...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/9580292
更新日期：2018-04-19 00:00:00
abstract：Purpose:To assess the effect of age on elevation and pachymetric Pentacam keratoconus (KC) detection indices, and the need to adjust normative values accordingly. Methods:In a retrospective study, 95 eyes of myopic normal subjects without KC were evaluated using the OCULUS Pentacam, with an age range of 17.4 to 46.8 y...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/2016564
更新日期：2018-04-22 00:00:00
abstract：PURPOSE:To investigate neovascular age-related macular degeneration (AMD) in patients aged ≥90 years from several perspectives for a comprehensive overview: prevalence, presenting characteristics, treatment adherence, reasons for discontinuation, and efficacy of antivascular endothelial growth factor (VEGF) treatment c...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/7194927
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:To date, the topic of amblyopic changes remains controversial. Therefore, a systematic review and meta-analysis were carried out to evaluate choroidal changes in unilateral amblyopia. METHODS:Major literature databases were searched for amblyopia-relevant studies. Using enhanced depth imaging optical coherence...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2017/2915261
更新日期：2017-01-01 00:00:00
abstract：Purpose:The purpose of this study was to evaluate 2-year visual outcomes in patients with diabetic macular edema (DME) treated with anti-VEGF agents in a routine clinical setting. Methods:The medical records of patients treated with ranibizumab or aflibercept due to DME at the Eye Hospital, University Medical Centre L...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/6979758
更新日期：2020-03-16 00:00:00
abstract：:Purpose. To compare anterior chamber depth (ACD), representing the distance between the anterior corneal surface and anterior lens surface measurements between the Galilei Dual Scheimpflug Analyzer and the IOLMaster. Methods. A retrospective review of 65 individual patient eyes with normal anterior segments, and no pr...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2012/430249
更新日期：2012-01-01 00:00:00
abstract：Purpose:Glaucoma is the leading cause of irreversible blindness throughout the world. The pathogenesis of glaucoma is complex, and neuroprotection is a crucial aspect of therapy. High concentrations of extracellular glutamate are toxic to the optic nerve. The glutamate-aspartate transporter (GLAST) in retinal Müller ce...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/6128470
更新日期：2018-10-31 00:00:00
abstract：:The functional visual acuity test which is the average of the visual acuities measured during a specific time frame (standard, 60 seconds) has been used recently to assess the visual function in various conditions. The availability of a shorter version of the functional visual acuity test promises to be patient friend...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/8950418
更新日期：2019-09-10 00:00:00
abstract：:Purpose. To compare near, intermediate, and distance vision and quality of vision, when refractive rotational multifocal intraocular lenses with 3.0 diopters or diffractive multifocal intraocular lenses with 2.5 diopters near addition are implanted. Methods. 41 eyes of 41 patients in whom rotational +3.0 diopters near...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/1395302
更新日期：2016-01-01 00:00:00
abstract：Purpose:Bilateral choroidal ganglioneuroma is extremely rare, and no cases have been described in the literature. Multimodal images are crucial for its diagnosis. Here, we evaluated multimodal images in the early stage of choroidal ganglioneuroma. Methods:A 6-year-old boy was recruited who had experienced gradually pr...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/6231269
更新日期：2020-05-11 00:00:00
abstract：Purpose:Visual loss is a devastating perioperative complication that can result from elevated intraocular pressure (IOP). The Trendelenburg position during surgery increases IOP. The purpose of this study was to quantify IOP changes in patients undergoing laparoscopic hysterectomy, at different time points and body pos...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/1457851
更新日期：2018-03-15 00:00:00
abstract：:Current data permit only speculations regarding sex differences in the prevalence of infectious uveitis between women and men because uveitis case surveys do not uniformly report gender data. Differences in prevalence that are reported in the literature could relate to simple differences in the number of women and men...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2014/683246
更新日期：2014-01-01 00:00:00
abstract：:Purpose. To compare dry eye disease following SMILE versus FS-LASIK. Design. Prospective, nonrandomised, observational study. Patients. 90 patients undergoing refractive surgery for myopia were included. 47 eyes underwent SMILE and 43 eyes underwent FS-LASIK. Methods. Evaluation of dry eye disease was conducted preope...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/132417
更新日期：2015-01-01 00:00:00
