Intravitreal and subconjunctival melphalan for retinoblastoma in transgenic mice.

abstract：:The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration or apoptosis patterns of photoreceptors are still unclear in rd11 mi...

journal_title：Journal of ophthalmology

authors： Zhang H,Li X,Dai X,Han J,Zhang Y,Qi Y,He Y,Liu Y,Chang B,Pang JJ

更新日期：2017-01-01 00:00:00

abstract：Purpose:To evaluate the effect of corneal cap thickness on visual acuity and corneal biomechanics in small incision lenticule extraction (SMILE) for the treatment of myopia. Methods:Forty eyes of 20 patients undergoing SMILE for the treatment of myopia were enrolled in this prospective controlled study. The patients w...

journal_title：Journal of ophthalmology

authors： Liu T,Yu T,Liu L,Chen K,Bai J

更新日期：2018-06-28 00:00:00

abstract：:Purpose. To compare anterior chamber depth (ACD), representing the distance between the anterior corneal surface and anterior lens surface measurements between the Galilei Dual Scheimpflug Analyzer and the IOLMaster. Methods. A retrospective review of 65 individual patient eyes with normal anterior segments, and no pr...

journal_title：Journal of ophthalmology

authors： Patel RP,Pandit RT

更新日期：2012-01-01 00:00:00

abstract：Aim:The purpose of this study is to evaluate and compare the efficacy of 4 prostaglandin analogues (PGAs) and to determine the incidence of ocular surface disease in newly diagnosed, primary open-angle glaucoma (POAG) patients started on one of those 4 PGAs: bimatoprost (benzalkonium chloride, BAK, 0.3 mg/mL), latanopr...

journal_title：Journal of ophthalmology

authors： El Hajj Moussa WG,Farhat RG,Nehme JC,Sahyoun MA,Schakal AR,Jalkh AE,Abi Karam MP,Azar GG

更新日期：2018-03-07 00:00:00

abstract：Purpose:Visual loss is a devastating perioperative complication that can result from elevated intraocular pressure (IOP). The Trendelenburg position during surgery increases IOP. The purpose of this study was to quantify IOP changes in patients undergoing laparoscopic hysterectomy, at different time points and body pos...

journal_title：Journal of ophthalmology

authors： Alexander I,Ahmad S,Inbar BS,Joseph P

更新日期：2018-03-15 00:00:00

abstract：:Objective. To describe the clinicoradiological and histopathological findings in a case of lacrimal gland enlargement secondary to lymphomatoid granulomatosis (LG) and to review the literature. Design. Case report and systematic literature review. Methods. A 75-year-old woman presented with right ptosis. Computerised ...

journal_title：Journal of ophthalmology

authors： Pradeep TG,Cannon P,Dodd T,Selva D

更新日期：2010-01-01 00:00:00

abstract：:Purpose. To evaluate the outcome of combined vitrectomy with phacoemulsification without postoperative face-down positioning for idiopathic macular holes (MHs). Design. Retrospective, observational case series. Participants. Forty-two eyes of 42 patients with MH. Methods. We studied 42 eyes of 42 cases followed up for...

journal_title：Journal of ophthalmology

authors： Yagi F,Takagi S,Tomita G

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To evaluate sequential changes in choroidal thickness at the affected area in patients with acute zonal occult outer retinopathy (AZOOR). METHODS:This retrospective observational case series included 14 affected eyes and 6 unaffected fellow eyes from 10 AZOOR patients with impaired macular area. Using enhanced...

journal_title：Journal of ophthalmology

authors： Hashimoto Y,Saito W,Saito M,Hasegawa Y,Takita A,Mori S,Noda K,Ishida S

更新日期：2017-01-01 00:00:00

abstract：:SD-OCT has become an essential tool for evaluating macular pathology; however several aspects of data collection and analysis affect the accuracy of retinal thickness measurements. Here we evaluated sampling density, scan centering, and axial length compensation as factors affecting the accuracy of macular thickness m...

journal_title：Journal of ophthalmology

authors： Odell D,Dubis AM,Lever JF,Stepien KE,Carroll J

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of the Rho-kinase inhibitor Y-27632 on postoperative inflammation and adhesion following extraocular muscle surgery in rabbits. METHODS:The superior rectus muscle reinsertion was performed on both eyes of 8 New Zealand white rabbits. After reinsertion, the rabbits received subconjunctiva...

journal_title：Journal of ophthalmology

authors： Moon JS,Kim HK,Shin SY

更新日期：2017-01-01 00:00:00

abstract：:Aim. To assess the effects of mydriatics commonly used in clinical practice on choroidal thickness and anterior chamber change. Methods. This was a prospective, randomized, controlled, double-blinded study including a single eye of the participants. The subjects were assigned into 4 groups to receive tropicamide 1%, p...

journal_title：Journal of ophthalmology

authors： Yuvacı İ,Pangal E,Yuvacı S,Bayram N,Ataş M,Başkan B,Demircan S,Akal A

更新日期：2015-01-01 00:00:00

abstract：Purpose:Although optical coherence tomography (OCT) is essential for ophthalmologists, reading of findings requires expertise. The purpose of this study is to test deep learning with image augmentation for automated detection of chorioretinal diseases. Methods:A retina specialist diagnosed 1,200 OCT images. The diagno...

journal_title：Journal of ophthalmology

authors： Kuwayama S,Ayatsuka Y,Yanagisono D,Uta T,Usui H,Kato A,Takase N,Ogura Y,Yasukawa T

更新日期：2019-04-09 00:00:00

abstract：:Idiopathic full-thickness macular hole is a severe visual impairment disease. Pars plana vitrectomy remains the primary treatment option for idiopathic full-thickness macular holes, and over 90% idiopathic full-thickness macular holes are closed by vitrectomy surgery. However, the full-thickness macular hole may close...

journal_title：Journal of ophthalmology

authors： Liang X,Liu W

更新日期：2019-03-13 00:00:00

abstract：:Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. The objective of this study is to investigate the effects of vascular endothelial growth factor receptor 1 (VEGFR1) blockade on the complications of DR. Experimental models of diabetes were induced with streptozotocin (STZ) treatment or I...

journal_title：Journal of ophthalmology

authors： He J,Wang H,Liu Y,Li W,Kim D,Huang H

更新日期：2015-01-01 00:00:00

abstract：Purpose:Lanosterol synthase (LSS) abnormity contributes to lens opacity in rats, mice, dogs, and human congenital cataract development. This study examined whether LSS pathway has a role in different subtypes of age-related cataract (ARC). Methods:A total of 390 patients with ARC and 88 age-matched non-ARC patients we...

journal_title：Journal of ophthalmology

authors： Shen X,Zhu M,Kang L,Tu Y,Li L,Zhang R,Qin B,Yang M,Guan H

更新日期：2018-07-11 00:00:00

abstract：:Objective. We aimed to assess peripheral vascular endothelial function in open-angle glaucoma (POAG) by measuring flow-mediated dilatation (FMD). Materials and Methods. The study included 20 cases with POAG (group 1, mean age 58.68 ± 13.3 years) and 30 healthy individuals (group 2, mean age 58.68 ± 13.6 years). In all...

journal_title：Journal of ophthalmology

authors： Atas M,Arifoglu HB,Hashas AS,Sarli B,Demircan S,Ozkose A,Goktas A

更新日期：2014-01-01 00:00:00

abstract：:The ciliary body ablation is still considered as a last resort treatment to reduce the intraocular pressure (IOP) in uncontrolled glaucoma. Several ablation techniques have been proposed over the years, all presenting a high rate of complications, nonselectivity for the target organ, and unpredictable dose-effect rela...

journal_title：Journal of ophthalmology

authors： Mastropasqua R,Fasanella V,Mastropasqua A,Ciancaglini M,Agnifili L

更新日期：2017-01-01 00:00:00

abstract：:Purpose. To evaluate the neutrophil/lymphocyte ratio (NLR) and the platelet/lymphocyte ratio(PLR) value in the development of branch retinal vein occlusion (BRVO)patients. METHODS:81 patients with BRVO and 81 age and sex-matched subjects were recruited as the control group. The BRVO diagnosis was confirmed under comp...

journal_title：Journal of ophthalmology

authors： Zhu DD,Liu X

更新日期：2019-10-31 00:00:00

abstract：:Purpose. This study retrospectively analyzed cataract surgeries to examine the usefulness of Surgical Media Center (SMC) (Abbott Medical Optics Inc.), a new cataract surgery recording device, for training of cataract surgery. Methods. We studied five hundred cataract surgeries conducted with a phacoemulsification syst...

journal_title：Journal of ophthalmology

authors： Ogawa T,Shiba T,Tsuneoka H

更新日期：2016-01-01 00:00:00

abstract：Purpose:To report a novel technique of cross-knotted suture basket and to test its effectiveness in large nonmagnetic intraocular foreign body (IOFB) removal. Methods:A 7/0 Vicryl suture was cut in half and cross-knotted, and four ends were introduced into a 23G needle to form a basket. Pig eyes were used to set up th...

journal_title：Journal of ophthalmology

authors： Cao J,Chen B,Li Y

更新日期：2020-04-25 00:00:00

abstract：:Background. The effect of angiotensin converting enzyme inhibitors (ACEi) on regression of retinopathy in type 2 diabetics is still ill defined. Methods. We compared the incidence of retinopathy regression in 90 hypertensive type 2 diabetics randomized to at least 3-year blinded ACEi with trandolapril (2 mg/day) or no...

journal_title：Journal of ophthalmology

authors： Ruggenenti P,Iliev I,Filipponi M,Tadini S,Perna A,Ganeva M,Ene-Iordache B,Cravedi P,Trevisan R,Bossi A,Remuzzi G

更新日期：2010-01-01 00:00:00

abstract：Purpose:To evaluate the changes in retinal vessel density and thickness after small incision lenticule extraction (SMILE) with optical coherence tomography angiography (OCTA) in myopic patients. Methods:In this prospective study, SMILE surgeries were done in 46 eyes of 24 patients with spherical equivalent (SE) more t...

journal_title：Journal of ophthalmology

authors： Chen M,Dai J,Gong L

更新日期：2019-05-20 00:00:00

abstract：:Purpose. To evaluate interobserver, intervisit, and interinstrument agreements for gonioscopy and Fourier domain anterior segment optical coherence tomography (FD ASOCT) for classifying open and narrow angle eyes. Methods. Eighty-six eyes with open or narrow anterior chamber angles were included. The superior angle wa...

journal_title：Journal of ophthalmology

authors： Rigi M,Bell NP,Lee DA,Baker LA,Chuang AZ,Nguyen D,Minnal VR,Feldman RM,Blieden LS

更新日期：2016-01-01 00:00:00

abstract：:Purpose. To examine the influence of positional misalignments on intraocular pressure (IOP) measurement with a rebound tonometer. Methods. Using the iCare rebound tonometer, IOP readings were taken from the right eye of 36 healthy subjects at the central corneal apex (CC) and compared to IOP measures using the Goldman...

journal_title：Journal of ophthalmology

authors： Beasley IG,Laughton DS,Coldrick BJ,Drew TE,Sallah M,Davies LN

更新日期：2013-01-01 00:00:00

abstract：Purpose:To compare the impact of visual field (VF) testing on intraocular pressure (IOP) change trends between healthy subjects and glaucoma patients. Methods:We recruited healthy volunteer subjects who did not have previous ocular diseases and open-angle glaucoma patients who were medically controlled well. IOP in bo...

journal_title：Journal of ophthalmology

authors： Li M,Zheng B,Wang Q,Sun X

更新日期：2020-07-04 00:00:00

abstract：:Aim. To examine subscale and total scores of NEI-VFQ questionnaire of type 2 diabetes patients at different diabetic retinopathy (DRP) stages. Methods. A total number of 201 patients have been included. Prior to ophthalmological examination all patients participated in the NEI-VFQ questionnaire. The patients were divi...

journal_title：Journal of ophthalmology

authors： Akkaya S,Düzova S,Şahin Ö,Kazokoğlu H,Bavbek T

更新日期：2016-01-01 00:00:00

abstract：:Objective. The purpose of this study was to examine how patient, physician, and situational factors are associated with the extent to which providers educate patients about glaucoma and glaucoma medications, and which patient and provider characteristics are associated with whether providers educate patients about gla...

journal_title：Journal of ophthalmology

authors： Sleath B,Blalock SJ,Carpenter DM,Muir KW,Sayner R,Lawrence S,Giangiacomo AL,Hartnett ME,Tudor G,Goldsmith J,Robin AL

更新日期：2014-01-01 00:00:00

abstract：Objective:To report the 15-year trend in ophthalmic presentations to the emergency department (ED) at the only medical center in Lebanon that provides 24-hour ophthalmologic care. Methods:Retrospective review of 1967 patients presenting to the ED with eye-related complaints between September 1997 and August 1998 and b...

journal_title：Journal of ophthalmology

authors： Salti HI,Mehanna CJ,Abiad B,Ghazi N,Raad S,Barikian A,Haddad R,Ashkar A,Harmouche E,Zaghrini E,Mufarrij A

更新日期：2018-03-13 00:00:00

abstract：:Background. We aimed to evaluate the association between maternal smoking and the occurrence of childhood refractive error and amblyopia. Methods. Relevant articles were identified from PubMed and EMBASE up to May 2015. Combined odds ratio (OR) corresponding with its 95% confidence interval (CI) was calculated to eval...

journal_title：Journal of ophthalmology

authors： Li L,Qi Y,Shi W,Wang Y,Liu W,Hu M

更新日期：2016-01-01 00:00:00

abstract：:Purpose. To evaluate the ability of spectral-domain optical coherence tomography to detect subtle amounts of retinal fluid when the choroidal neovascularization is detected as inactive via time-domain optical coherence tomography and clinical examination in neovascular age-related macular degeneration (nAMD) patients....

journal_title：Journal of ophthalmology

authors： Ozkaya A,Alkin Z,Ozkaya HM,Agca A,Ozgurhan EB,Karakucuk Y,Yazici AT,Demirok A

更新日期：2013-01-01 00:00:00