Abstract：
:Purpose. To examine the influence of positional misalignments on intraocular pressure (IOP) measurement with a rebound tonometer. Methods. Using the iCare rebound tonometer, IOP readings were taken from the right eye of 36 healthy subjects at the central corneal apex (CC) and compared to IOP measures using the Goldmann applanation tonometer (GAT). Using a bespoke rig, iCare IOP readings were also taken 2 mm laterally from CC, both nasally and temporally, along with angular deviations of 5 and 10 degrees, both nasally and temporally to the visual axis. Results. Mean IOP ± SD, as measured by GAT, was 14.7 ± 2.5 mmHg versus iCare tonometer readings of 17.4 ± 3.6 mmHg at CC, representing an iCare IOP overestimation of 2.7 ± 2.8 mmHg (P < 0.001), which increased at higher average IOPs. IOP at CC using the iCare tonometer was not significantly different to values at lateral displacements. IOP was marginally underestimated with angular deviation of the probe but only reaching significance at 10 degrees nasally. Conclusions. As shown previously, the iCare tonometer overestimates IOP compared to GAT. However, IOP measurement in normal, healthy subjects using the iCare rebound tonometer appears insensitive to misalignments. An IOP underestimation of <1 mmHg with the probe deviated 10 degrees nasally reached statistical but not clinical significance levels.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Beasley IG,Laughton DS,Coldrick BJ,Drew TE,Sallah M,Davies LNdoi
10.1155/2013/791084subject
Has Abstractpub_date
2013-01-01 00:00:00pages
791084eissn
2090-004Xissn
2090-0058journal_volume
2013pub_type
杂志文章abstract：:Purpose. To evaluate interobserver, intervisit, and interinstrument agreements for gonioscopy and Fourier domain anterior segment optical coherence tomography (FD ASOCT) for classifying open and narrow angle eyes. Methods. Eighty-six eyes with open or narrow anterior chamber angles were included. The superior angle wa...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/1727039
更新日期：2016-01-01 00:00:00
abstract：:Background. The effect of angiotensin converting enzyme inhibitors (ACEi) on regression of retinopathy in type 2 diabetics is still ill defined. Methods. We compared the incidence of retinopathy regression in 90 hypertensive type 2 diabetics randomized to at least 3-year blinded ACEi with trandolapril (2 mg/day) or no...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2010/106384
更新日期：2010-01-01 00:00:00
abstract：:Purpose. To review the newer treatments for bacterial keratitis. Data Sources. PubMed literature search up to April 2012. Study Selection. Key words used for literature search: "infectious keratitis", "microbial keratitis", "infective keratitis", "new treatments for infectious keratitis", "fourth generation fluoroquin...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2012/831502
更新日期：2012-01-01 00:00:00
abstract：:Purpose. To assess the different check sizes of pattern visual evoked potential (PVEP) in diabetic patients without retinopathy according to HbA1c levels and diabetes duration. Methods. Fifty-eight eligible patients with type 2 diabetes mellitus and 26 age- and sex-matched healthy controls were included in the study. ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/8597629
更新日期：2017-01-01 00:00:00
abstract：:Purpose. To investigate the effect of cigarette smoking on the ocular tear film. Methods. Thirty healthy young male cigarette smokers (20-38 years old) and 30 healthy age matched nonsmokers were enrolled in the study. McMonnies questionnaire, slit lamp, and PRT test were used to screen the subjects. Tear samples were ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/8154315
更新日期：2016-01-01 00:00:00
abstract：:Here we review evidence that loss of photoreceptors due to degenerative retinal disease causes an increase in the rate of spontaneous ganglion spike discharge. Information about persistent spike activity is important since it is expected to add noise to the communication between the eye and the brain and thus impact t...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2011/507037
更新日期：2011-01-01 00:00:00
abstract：:Retinitis pigmentosa (RP) represents a clinically and genetically heterogeneous disease characterized by progressive photoreceptor loss. In recent years, research has been rarely made in blood flow affected in RP. The specific mechanism of blood flow affected in RP is not completely clear. A number of studies indicate...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2018/3249064
更新日期：2018-02-25 00:00:00
abstract：:Purpose. This study investigated the effects of oral propolis on the progression of galactose-induced sugar cataracts in rats and the in vitro effects of propolis on high-glucose-induced reactive oxygen species (ROS) and cell death in cultured rat lens cells (RLECs). Methods. Galactose-fed rats and RLECs cultured in h...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/1917093
更新日期：2016-01-01 00:00:00
abstract：:The ciliary body ablation is still considered as a last resort treatment to reduce the intraocular pressure (IOP) in uncontrolled glaucoma. Several ablation techniques have been proposed over the years, all presenting a high rate of complications, nonselectivity for the target organ, and unpredictable dose-effect rela...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2017/7136275
更新日期：2017-01-01 00:00:00
abstract：Purpose:The aim of this study was to assess the effects of residual anterior lens epithelial cell (LEC) removal by anterior capsule polishing on the effective lens position (ELP) and axial position stability of the intraocular lens (IOL) after cataract surgery via postoperative measurement of the anterior chamber depth...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/9704892
更新日期：2018-08-19 00:00:00
abstract：:There is growing evidence that chronic inflammation plays a role in both the development and progression of diabetic retinopathy. There is also evidence that molecules produced as a result of hyperglycemia can activate microglia. However the exact contribution of microglia, the resident immune cells of the central ner...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2014/705783
更新日期：2014-01-01 00:00:00
abstract：Objective:To calculate the Q values from the human anterior corneal surface with the tangential radius of curvature and analyze its distribution characteristics in different age and refractive status groups. Methods:Tangential power maps of the anterior cornea from Orbscan II were acquired for 201 subjects' right eyes...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/7263564
更新日期：2018-04-17 00:00:00
abstract：:Purpose. To evaluate visual and safety outcomes of 23-gauge (G) pars plana vitrectomy (PPV) with application of perfluorocarbon liquid (PFCL) for intraoperative protection of the macula during intraocular foreign body (IOFB) removal. Methods. Retrospective study of 42 patients who underwent 23 G PPV for IOFB removal f...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/6232151
更新日期：2017-01-01 00:00:00
abstract：:Individualized treatment regimens may reduce patient burden with satisfactory patient outcomes in neovascular age-related macular degeneration. Intravitreal anti-VEGF drugs are the current gold standard. Fixed monthly injections offer the best visual outcome but this regimen is not commonly followed outside clinical t...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2015/412903
更新日期：2015-01-01 00:00:00
abstract：Purpose:To identify and correlate age-related changes in outer retinal layers' thickness and choroidal thickness (CT) in the normal eyes using spectral-domain optical coherence tomography (SD-OCT) and to investigate factors affecting these changes. Study Design:Observational cross-sectional study. Subjects and Method...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/1698967
更新日期：2019-07-31 00:00:00
abstract：:Purpose. To compare fluorescein angiography (FA) and optical coherence tomography angiography (OCTA) images of foveal avascular zone (FAZ) in patients with diabetic retinopathy (DR) with and without diabetic macular ischemia (DMI). Methods. The Wilcoxon signed-rank test was used to compare area measurements and p valu...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/3989310
更新日期：2016-01-01 00:00:00
abstract：:Familial exudative vitreoretinopathy (FEVR) is a hereditary ocular disorder characterized by incomplete vascularization/abnormality of peripheral retina. Four of the identified disease-causing genes of FEVR were NDP, FZD4, LRP5, and TSPAN12, the protein coded by which were the components of the Norrin/β-catenin signal...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2019/5782536
更新日期：2019-11-16 00:00:00
abstract：Purpose:This study aims to assess scleral and conjunctival thickness using optical coherence tomography after ultrasound ciliary plasty (UCP) procedure with reference to scleral marks appearing in the area where the ultrasound energy was applied. Materials and Methods:Seventy-eight patients with primary and secondary ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/9659014
更新日期：2020-09-24 00:00:00
abstract：Purpose:Visual loss is a devastating perioperative complication that can result from elevated intraocular pressure (IOP). The Trendelenburg position during surgery increases IOP. The purpose of this study was to quantify IOP changes in patients undergoing laparoscopic hysterectomy, at different time points and body pos...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/1457851
更新日期：2018-03-15 00:00:00
abstract：Purpose:To evaluate parent knowledge of screening and genetic testing for retinoblastoma and its potential correlation with demographics, clinical features, and socioeconomical factors. Methods:It was a cross-sectional study conducted at the ocular oncology unit of a tertiary ophthalmic center in Southern China. A fac...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/3839792
更新日期：2020-04-08 00:00:00
abstract：Purpose:To investigate the association between regional solar radiation and myopia occurrence in South Korean children. Materials and Methods:A population-based cross-sectional study using data of 1218 children aged 7-9 years from the Korea National Health and Nutritional Examination Survey was conducted from January ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/7643850
更新日期：2019-06-10 00:00:00
abstract：Objective:To determine whether accommodation induced by reading alters intraocular pressure (IOP) in healthy, young, emmetropic adults and to document the duration and magnitude of this effect. Design:Cross-sectional study. Participants. Fifteen healthy, emmetropic young adults. Methods:Subjects performed 20 minutes ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/1352434
更新日期：2020-01-28 00:00:00
abstract：Purpose:To determine the significance of any association between intersessional changes in ocular residual astigmatism (RA) and astigmatism at corneal front (FSA) and back (BSA) surfaces following uneventful routine phacoemulsification. Methods:Astigmatism was evaluated by autorefractometry and subjective refraction a...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/7395081
更新日期：2020-07-22 00:00:00
abstract：:Purpose. To investigate the association of birth parameters with refractive status in different age groups of Caucasian children. Materials and Methods. This cross-sectional study included 564 eyes of 282 children aged 4 to 17 years. All children underwent complete ophthalmologic examination. The children were divided...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/635682
更新日期：2015-01-01 00:00:00
abstract：:The leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4, also called GPR48) plays a key role in multiple developmental processes, and mice lacking Lgr4 display anterior segment dysgenesis leading to early-onset glaucomatous retinal ganglion cell loss as well as defective eyelid formation. This paper will...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2013/987494
更新日期：2013-01-01 00:00:00
abstract：:Objective. Compare glaucoma medication costs between the United States (USA) and Canada. Methods. We modelled glaucoma brand name and generic medication annual costs in the USA and Canada based on October 2013 Costco prices and previously reported bottle overfill rates, drops per mL, and wastage adjustment. We also ca...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/547960
更新日期：2015-01-01 00:00:00
abstract：:Diabetic retinal complications, including macular edema (DME) and proliferative diabetic retinopathy (PDR), are the leading cause of new cases of blindness among adults aged 20-74. Chronic hyperglycemia, considered the underlying cause of diabetic retinopathy, is thought to act first through violation of the pericyte-...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2012/209538
更新日期：2012-01-01 00:00:00
abstract：:We established a chronic dacryocystitis model by injecting of 0.05, 0.1, and 0.15 ml self-curing resin via the lacrimal punctum in rabbits. Animals were randomized into four groups (n = 11 animals/group). The control group received 0.15 ml normal saline. Within three months postinjection, epiphora and eye discharge we...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/3438041
更新日期：2017-01-01 00:00:00
abstract：:Purpose. To evaluate the outcome of combined vitrectomy with phacoemulsification without postoperative face-down positioning for idiopathic macular holes (MHs). Design. Retrospective, observational case series. Participants. Forty-two eyes of 42 patients with MH. Methods. We studied 42 eyes of 42 cases followed up for...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2012/571748
更新日期：2012-01-01 00:00:00
abstract：Background:Endoplasmic reticulum stress (ERS) in the retinal Müller cells is a key factor contributing to the retinal inflammation and vascular leakage in diabetic retinopathy (DR). This study was to investigate the underlying mechanisms through which the 3 main unfolded protein response (UPR) pathways regulate ERS and...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/9028483
更新日期：2019-02-24 00:00:00
