Abstract:
:Background. The effect of angiotensin converting enzyme inhibitors (ACEi) on regression of retinopathy in type 2 diabetics is still ill defined. Methods. We compared the incidence of retinopathy regression in 90 hypertensive type 2 diabetics randomized to at least 3-year blinded ACEi with trandolapril (2 mg/day) or non-ACEi therapy who had preproliferative or proliferative retinopathy at baseline. Results. Over a median (interquartile range) follow-up period of 35.8 (12.4-60.7) months, retinopathy regressed in 27 patients (30.0%). Regression occurred in 18 of 42 patients (42.9%) on ACEi and in 9 of 48 (18.8%) on non-ACEi therapy (adjusted for predefined baseline covariates HR (95% CI): 2.75 (1.18-6.42), P = .0193). Concomitant treatment with or without Non-Dihydropyridine Calcium Channel Blockers (ndCCBs) did not appreciably affect the incidence of retinopathy regression. Conclusions. Unlike ndCCB, ACEi therapy may have an additional effect to that of intensified BP and metabolic control in promoting regression of diabetic retinopathy.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Ruggenenti P,Iliev I,Filipponi M,Tadini S,Perna A,Ganeva M,Ene-Iordache B,Cravedi P,Trevisan R,Bossi A,Remuzzi Gdoi
10.1155/2010/106384subject
Has Abstractpub_date
2010-01-01 00:00:00pages
106384eissn
2090-004Xissn
2090-0058journal_volume
2010pub_type
杂志文章abstract::Background. The vision with diffractive toric multifocal intraocular lenses after cataract surgery in long eyes has not been studied previously. Objectives. To report visual performance after bilateral implantation of a diffractive toric multifocal intraocular lens in high myopes. Methods. Prospective, observational c...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/5320105
更新日期:2016-01-01 00:00:00
abstract:Background:Bardet-Biedl syndrome (BBS) is a rare multisystem developmental disorder. In this study, we report the genetic causes and clinical manifestations in two Chinese families with BBS. Materials and Methods:Two families were recruited in this study. Family A was a four-generation family with four affected and 15...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2021/6751857
更新日期:2021-01-06 00:00:00
abstract::Purpose. To evaluate visual and safety outcomes of 23-gauge (G) pars plana vitrectomy (PPV) with application of perfluorocarbon liquid (PFCL) for intraoperative protection of the macula during intraocular foreign body (IOFB) removal. Methods. Retrospective study of 42 patients who underwent 23 G PPV for IOFB removal f...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/6232151
更新日期:2017-01-01 00:00:00
abstract:Purpose:Activating transcription factor 4 (ATF4) is induced by various stressors. Here, we investigated the expression of ATF4 in the host inflammatory response to Aspergillus fumigatus (A. fumigatus) keratitis. Methods:A. fumigatus keratitis mouse models developed by intrastromal injection as well as corneal epitheli...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/5830202
更新日期:2018-12-13 00:00:00
abstract::Cross-linking of corneal collagen (CXL) is a promising approach for the treatment of keratoconus and secondary ectasia. Several long-term and short-term complications of CXL have been studied and documented. The possibility of a secondary infection after the procedure exists because the patient is subjected to epithel...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/869015
更新日期:2011-01-01 00:00:00
abstract:Purpose:Although optical coherence tomography (OCT) is essential for ophthalmologists, reading of findings requires expertise. The purpose of this study is to test deep learning with image augmentation for automated detection of chorioretinal diseases. Methods:A retina specialist diagnosed 1,200 OCT images. The diagno...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/6319581
更新日期:2019-04-09 00:00:00
abstract:Background:To evaluate the outcome and complications of transscleral suture-fixated posterior chamber intraocular lens (PCIOL) implantation combined with Ahmed glaucoma valve (AGV) surgery in Asian eyes. Design:This was a retrospective study that included 22 eyes from 22 participants. The surgeries were performed at S...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/9824035
更新日期:2018-03-25 00:00:00
abstract::Genome-wide association study (GWAS) analysis identified three new susceptibility loci for PACG. In this study, we aimed to investigate whether these three loci in PLEKHA7, COL11A1, and PCMTD1-ST18 are associated with PAC and ocular biometric characteristics, such as axial length (AL), anterior chamber depth (ACD), an...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/641596
更新日期:2013-01-01 00:00:00
abstract::Purpose. To evaluate intraobserver and interobserver agreement in locating the scleral spur landmark (SSL) and anterior chamber angle measurements obtained using Fourier Domain Anterior Segment Optical Coherence Tomography (ASOCT) images. Methods. Two independent, masked observers (SR and AZC) identified SSLs on ASOCT...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/487309
更新日期:2012-01-01 00:00:00
abstract::Purpose. To compare dry eye disease following SMILE versus FS-LASIK. Design. Prospective, nonrandomised, observational study. Patients. 90 patients undergoing refractive surgery for myopia were included. 47 eyes underwent SMILE and 43 eyes underwent FS-LASIK. Methods. Evaluation of dry eye disease was conducted preope...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/132417
更新日期:2015-01-01 00:00:00
abstract:Purpose:To identify the clinical characteristics and risk factors for secondary choroidal neovascularization (CNV) in central serous chorioretinopathy (CSC). Methods:In this retrospective study, we included a total of 108 eyes in 106 CSC patients. Group A was defined as patients initially diagnosed with CSC who develo...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/7217906
更新日期:2020-02-07 00:00:00
abstract:PURPOSE:To date, the topic of amblyopic changes remains controversial. Therefore, a systematic review and meta-analysis were carried out to evaluate choroidal changes in unilateral amblyopia. METHODS:Major literature databases were searched for amblyopia-relevant studies. Using enhanced depth imaging optical coherence...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2017/2915261
更新日期:2017-01-01 00:00:00
abstract:Purpose:Visual loss is a devastating perioperative complication that can result from elevated intraocular pressure (IOP). The Trendelenburg position during surgery increases IOP. The purpose of this study was to quantify IOP changes in patients undergoing laparoscopic hysterectomy, at different time points and body pos...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/1457851
更新日期:2018-03-15 00:00:00
abstract:Purpose:To evaluate the effect of corneal cap thickness on visual acuity and corneal biomechanics in small incision lenticule extraction (SMILE) for the treatment of myopia. Methods:Forty eyes of 20 patients undergoing SMILE for the treatment of myopia were enrolled in this prospective controlled study. The patients w...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/6040873
更新日期:2018-06-28 00:00:00
abstract:Purpose:To evaluate early macular circulation in open-angle glaucoma (OAG), normal-tension glaucoma (NTG), ocular hypertension (OHT), and healthy subjects via optical coherence tomography angiography (OCTA). Methods:A retrospective cross-sectional study was conducted. Medical records were reviewed, and the patients wh...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/7419470
更新日期:2019-01-15 00:00:00
abstract::Purpose. To report the 12-month follow-up after big-bubble deep anterior lamellar keratoplasty (DALK) assisted by femtosecond laser that we have called IntraBubble. Methods. A 60 kHz IntraLase femtosecond laser (Abbott Medical Optics) firstly created a 30° angled intrastromal channel to insert the air injection cannul...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/264590
更新日期:2012-01-01 00:00:00
abstract:Introduction:To assess long-term efficacy of bimedial rectus tendon elongation with Tutopatch in thyroid-associated orbitopathy (TAO). Materials and Methods:Retrospective chart review of 5 patients with TAO undergoing bimedial rectus recession with Tutopatch tendon elongation between 2009 and 2015. We analyzed horizon...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/1294761
更新日期:2018-07-24 00:00:00
abstract::Aim. To investigate the utility of fundus autofluorescence (FAF) and optical coherence tomography (OCT) in the evaluation of cystoid macular edema (CME) following cataract surgery. Materials and Methods. Forty eyes of 29 patients undergone phacoemulsification, with posterior chamber intraocular lens implantation surge...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/376013
更新日期:2013-01-01 00:00:00
abstract::Purpose. To evaluate the outcome of combined vitrectomy with phacoemulsification without postoperative face-down positioning for idiopathic macular holes (MHs). Design. Retrospective, observational case series. Participants. Forty-two eyes of 42 patients with MH. Methods. We studied 42 eyes of 42 cases followed up for...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/571748
更新日期:2012-01-01 00:00:00
abstract::Purpose. To investigate the association of birth parameters with refractive status in different age groups of Caucasian children. Materials and Methods. This cross-sectional study included 564 eyes of 282 children aged 4 to 17 years. All children underwent complete ophthalmologic examination. The children were divided...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/635682
更新日期:2015-01-01 00:00:00
abstract::Purpose. To examine causes as well as extent of delay in diagnosis and treatment of primary open angle glaucoma patients in a sample of Egyptians. Patients and Methods. 440 patients with primary open angle glaucoma were interviewed to evaluate delay in their diagnosis and treatment. The extent and cause of delay were ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/7012826
更新日期:2016-01-01 00:00:00
abstract::Purpose. To compare the corneal endothelial cell loss after phacoemulsification, alone or combined with microinvasive glaucoma surgery (MIGS), in nonglaucomatous versus primary open angle glaucoma (POAG) eyes affected by age-related cataract. Methods. 62 eyes of 62 patients were divided into group 1 (n = 25, affected ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/769289
更新日期:2015-01-01 00:00:00
abstract::Purpose. To compare anterior chamber depth (ACD), representing the distance between the anterior corneal surface and anterior lens surface measurements between the Galilei Dual Scheimpflug Analyzer and the IOLMaster. Methods. A retrospective review of 65 individual patient eyes with normal anterior segments, and no pr...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/430249
更新日期:2012-01-01 00:00:00
abstract:Purpose:To evaluate parent knowledge of screening and genetic testing for retinoblastoma and its potential correlation with demographics, clinical features, and socioeconomical factors. Methods:It was a cross-sectional study conducted at the ocular oncology unit of a tertiary ophthalmic center in Southern China. A fac...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/3839792
更新日期:2020-04-08 00:00:00
abstract::Purpose. To evaluate the ability of spectral-domain optical coherence tomography to detect subtle amounts of retinal fluid when the choroidal neovascularization is detected as inactive via time-domain optical coherence tomography and clinical examination in neovascular age-related macular degeneration (nAMD) patients....
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/786107
更新日期:2013-01-01 00:00:00
abstract::Purpose. To investigate the thickness of the retinal nerve fiber layer (RNFL) and choroid in patients who have migraines in comparison to healthy controls. Methods. This study included 76 eyes and patients in the migraine group, 36 with aura (MWA group) and 40 without (MWoA group), and 38 eyes as control subjects. The...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/868967
更新日期:2015-01-01 00:00:00
abstract:Background:Chromatic contrast may affect stereopsis. Daltonism is a common color deficiency in which the colors red and green are incorrectly detected. The aim of this study was to evaluate the stereoacuity of color-defective individuals presented with color symbols that they see defectively. Methods:Ten students diag...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/1926736
更新日期:2018-08-01 00:00:00
abstract:Purpose:The aim of this work was to describe the ultrastructure and behavior of peeled internal limiting membrane (ILM) in macular hole (MH) surgery. Methods:Seven patients with MH were included, and vitrectomy with ILM peeling was performed in all patients. The ILM inverted flap technique was used. Two other flaps of...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/1345683
更新日期:2019-05-02 00:00:00
abstract::Aim. To evaluate the possible structural and functional changes in the retinal nerve fibre layer (RNFL) and the ganglion cell complex (GCC) of chronic smokers and compare them with those of passive healthy smokers using spectral domain optical coherence tomography (SD-OCT) and pattern electroretinogram (PERG). Materia...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/6354025
更新日期:2017-01-01 00:00:00
abstract:Purpose:To evaluate a new tangential map-based nomogram versus the axial map-based nomogram for ICRS in keratoconus. Methods:A prospective case series study including 64 eyes of 64 patients who underwent ICRS implantation. Cone location was determined for each eye with two maps: the axial and the tangential. Appropria...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/3983508
更新日期:2020-02-19 00:00:00