Abstract:
:Purpose. To evaluate the ability of spectral-domain optical coherence tomography to detect subtle amounts of retinal fluid when the choroidal neovascularization is detected as inactive via time-domain optical coherence tomography and clinical examination in neovascular age-related macular degeneration (nAMD) patients. Methods. Forty-nine eyes of 49 patients with nAMD after ranibizumab treatment were included in this cross-sectional, prospective study. All patients were imaged with TD-OCT and SD-OCT at the same visit one month after a ranibizumab injection. The presence of subretinal, intraretinal, and subretinal pigment epithelium fluid (subRPE) in SD-OCT was evaluated; also mean central retinal thickness (CRT) and the rate of vitreoretinal surface disorders detected via the two devices were evaluated. Results. The mean CRT via TD-OCT and SD-OCT was 218.1 ± 51.3 and 325.7 ± 78.8 microns. Sixteen patients (32.6%) showed any kind of retinal fluid via SD-OCT. In detail, 8 patients (16.3%) showed subretinal fluid, 10 patients (20.4%) showed intraretinal fluid, and 3 patients (6.1%) showed SubRPE fluid. The ability of detecting vitreoretinal surface disorders was comparable between the two devices, except vitreomacular traction. Conclusion. SD-OCT is essential for the nAMD patients who are on an as-needed treatment regimen with ranibizumab. Only TD-OCT and clinical examination may cause insufficient treatment in this group of patients.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Ozkaya A,Alkin Z,Ozkaya HM,Agca A,Ozgurhan EB,Karakucuk Y,Yazici AT,Demirok Adoi
10.1155/2013/786107subject
Has Abstractpub_date
2013-01-01 00:00:00pages
786107eissn
2090-004Xissn
2090-0058journal_volume
2013pub_type
杂志文章abstract::Purpose. We report the effect of isotretinoin on corneal topography, corneal thickness, and biomechanical parameters in patients with acne vulgaris. Method. Fifty-four eyes of 54 patients who received oral isotretinoin for treatment of acne vulgaris were evaluated. All patients underwent a corneal topographical evalua...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/701361
更新日期:2014-01-01 00:00:00
abstract::Glaucoma is one of the leading causes of blindness worldwide. Recent studies suggest that intraocular pressure (IOP) fluctuations, peaks, and rhythm are important factors in disease advancement. Yet, current glaucoma management remains hinged on single IOP measurements during clinic hours. To overcome this limitation,...
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journal_title:Journal of ophthalmology
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更新日期:2012-01-01 00:00:00
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journal_title:Journal of ophthalmology
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journal_title:Journal of ophthalmology
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pub_type: 杂志文章,评审
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journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2015/414781
更新日期:2015-01-01 00:00:00
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journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2015/412903
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abstract::[This corrects the article DOI: 10.1155/2016/3690140.]. ...
journal_title:Journal of ophthalmology
pub_type: 已发布勘误
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更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章,评审
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