Abstract:
:This paper demonstrates multiple benefits of intravitreal bevacizumab (IVB) on diabetic retinopathy (DR) including diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) at 24 months of followup. This is a retrospective multicenter interventional comparative case series of intravitreal injections of 1.25 or 2.5 mg of bevacizumab for DME, PDR without tractional retinal detachment (TRD), and patients who experienced the development or progression of TRD after an intravitreal injection of 1.25 or 2.5 mg of bevacizumab before vitrectomy for the management of PDR. The results indicate that IVB injections may have a beneficial effect on macular thickness and visual acuity (VA) in diffuse DME. Therefore, in the future this new therapy could complement focal/grid laser photocoagulation in DME. In PDR, this new option could be an adjuvant agent to panretina photocoagulation so that more selective therapy may be applied. Finally, TRD in PDR may occur or progress after IVB used as an adjuvant to vitrectomy. Surgery should be performed 4 days after IVB. Most patients had poorly controlled diabetes mellitus associated with elevated HbA1c, insulin administration, PDR refractory to panretinal photocoagulation, and longer time between IVB and vitrectomy.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Arevalo JF,Sanchez JG,Lasave AF,Wu L,Maia M,Bonafonte S,Brito M,Alezzandrini AA,Restrepo N,Berrocal MH,Saravia M,Farah ME,Fromow-Guerra J,Morales-Canton Vdoi
10.1155/2011/584238subject
Has Abstractpub_date
2011-01-01 00:00:00pages
584238eissn
2090-004Xissn
2090-0058journal_volume
2011pub_type
杂志文章abstract::Genome-wide association study (GWAS) analysis identified three new susceptibility loci for PACG. In this study, we aimed to investigate whether these three loci in PLEKHA7, COL11A1, and PCMTD1-ST18 are associated with PAC and ocular biometric characteristics, such as axial length (AL), anterior chamber depth (ACD), an...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/641596
更新日期:2013-01-01 00:00:00
abstract:Purpose:To compare ocular biometry between children with type 1 diabetes mellitus (T1DM) and healthy children in China and to determine the correlation of ocular biometry with the glycosylated hemoglobin (HbA1c) level and diabetes duration. Methods:A case-control study was conducted at Children's Hospital of Fudan Uni...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/7216490
更新日期:2019-02-14 00:00:00
abstract::Primary congenital glaucoma is a worldwide diagnostic and therapeutic challenge. Although medical management is often a temporizing measure, early surgical intervention is the definitive treatment. As the abundance of surgical treatment options continues to expand, the authors will compare and contrast the available o...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/612708
更新日期:2013-01-01 00:00:00
abstract::Aim. To investigate the utility of fundus autofluorescence (FAF) and optical coherence tomography (OCT) in the evaluation of cystoid macular edema (CME) following cataract surgery. Materials and Methods. Forty eyes of 29 patients undergone phacoemulsification, with posterior chamber intraocular lens implantation surge...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/376013
更新日期:2013-01-01 00:00:00
abstract::Objective. Compare glaucoma medication costs between the United States (USA) and Canada. Methods. We modelled glaucoma brand name and generic medication annual costs in the USA and Canada based on October 2013 Costco prices and previously reported bottle overfill rates, drops per mL, and wastage adjustment. We also ca...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/547960
更新日期:2015-01-01 00:00:00
abstract:Objective:To report the 15-year trend in ophthalmic presentations to the emergency department (ED) at the only medical center in Lebanon that provides 24-hour ophthalmologic care. Methods:Retrospective review of 1967 patients presenting to the ED with eye-related complaints between September 1997 and August 1998 and b...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/4739865
更新日期:2018-03-13 00:00:00
abstract::Purpose. To evaluate the anterior chamber volume in cataract patients with Swept-Source Optical Coherence Tomography (SS-OCT) and its influencing factors. Methods. Anterior chamber volume of 92 cataract patients was evaluated with SS-OCT in this cross-sectional study. Univariate analyses and multiple linear regression...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/8656301
更新日期:2016-01-01 00:00:00
abstract:Purpose:To evaluate the outcomes of femtosecond laser-assisted implantation of a 355-degree intracorneal ring (ICR) (Keraring) in patients with keratoconus in the three-year follow-up. Setting:Future Femtolaser Center, Sohag, Egypt. Design:Prospective interventional case series. Patients and Methods:A prospective ca...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/6783181
更新日期:2019-10-09 00:00:00
abstract:Objective:In a group case series, the clinical characteristics of congenital membranous cataract in children were studied to establish a system of classification and determine the surgical method suited for each type. Methods:Children (18 eyes) with congenital membranous cataract were examined by slit lamp, ultrasound...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/2370969
更新日期:2017-01-01 00:00:00
abstract::SD-OCT has become an essential tool for evaluating macular pathology; however several aspects of data collection and analysis affect the accuracy of retinal thickness measurements. Here we evaluated sampling density, scan centering, and axial length compensation as factors affecting the accuracy of macular thickness m...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/692574
更新日期:2011-01-01 00:00:00
abstract::Familial exudative vitreoretinopathy (FEVR) is a hereditary ocular disorder characterized by incomplete vascularization/abnormality of peripheral retina. Four of the identified disease-causing genes of FEVR were NDP, FZD4, LRP5, and TSPAN12, the protein coded by which were the components of the Norrin/β-catenin signal...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2019/5782536
更新日期:2019-11-16 00:00:00
abstract::Objective. To compare macular thickness (MT) and retinal nerve fiber layers (RNFL) between women with polycystic ovary syndrome (PCOS) and healthy women. Materials and Methods. The study included 45 women with PCOS and 47 ovulatory women undergoing clinical-gynecological and ophthalmic evaluations, including measureme...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/193078
更新日期:2015-01-01 00:00:00
abstract:AIM:To discuss the clinical characteristics of immune-related dry eye. METHODS:Simple dry eye (SDE) group: we selected 224 patients of simple dry eye with no systemic lesions. Immune-related dry eye (IRDE) group: we selected 207 patients of dry eye complicated with immune system diseases, including 70 cases of Sjögren...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/8532397
更新日期:2017-01-01 00:00:00
abstract:Purpose:To report the long-term follow-up results of posterior segment intraocular foreign body (IOFB) removal in children and to determine the prognostic factors for visual outcome. Methods:Design: retrospective, noncomparative, interventional case series; a single tertiary care center study. Participants or samples:...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/5861043
更新日期:2018-06-25 00:00:00
abstract:Purpose:To evaluate the feasibility and the initial outcomes of a novel standardized surgical technique of femtosecond laser- (FSL-) assisted big-bubble deep anterior lamellar keratoplasty (BBDALK) for eyes with keratoconus. Methods:This prospective interventional case series included 11 consecutive FSL-assisted BBDAL...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/5496162
更新日期:2020-09-03 00:00:00
abstract:OBJECTIVES:To analyse the changes of ocular haemodynamics and morphology in Chinese patients with internal carotid artery (ICA) stenosis in the current study. METHODS:A retrospective case-control study was conducted with 219 patients. The haemodynamic characteristics, the calibre of retinal vessels, and the subfoveal ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/1842176
更新日期:2017-01-01 00:00:00
abstract::Purpose. This study aims to explore the safety and efficacy of a novel treatment-intense pulsed light (IPL) in MGD eyes. Methods. This study is a prospective and open label study. Forty eyes of 40 MGD patients were recruited in the study and received 4 consecutive IPL treatments on day 1, day 15, day 45, and day 75. T...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/1910694
更新日期:2016-01-01 00:00:00
abstract:Purpose:To examine the morphological changes in the meibomian glands of patients with keratoconus as well as to study the relationship between these changes in the morphology and several tear film parameters. Methods:Examination of the meibomian gland (MG) of 300 keratoconus patients presenting to the center using inf...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/2965872
更新日期:2019-06-02 00:00:00
abstract::Congenital cataract is the most common cause of the visual disability and blindness in childhood. This study aimed to identify gene mutations responsible for autosomal dominant congenital cataract (ADCC) in a Chinese family using next-generation sequencing technology. This family included eight unaffected and five aff...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/4353957
更新日期:2016-01-01 00:00:00
abstract:Purpose:Studying the early effect of different extraocular muscle (EOM) surgeries on corneal biomechanics. Subjects and methods:This is a prospective, nonrandomized, interventional study, in which 42 eyes of 29 candidates for EOM surgery for strabismus correction at Cairo university hospitals, aged 14-37 years, were r...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/8072140
更新日期:2018-09-16 00:00:00
abstract:Introduction:Hepatitis B virus (HBV) and hepatitis C virus (HCV) and their long-term sequelae are considered a major health issue in Egypt. The aim of this study is to determine the prevalence of undiagnosed hepatitis B virus (HBV) and hepatitis C virus (HCV) among patients admitted for elective eye surgery in a specia...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/3985865
更新日期:2019-07-01 00:00:00
abstract::Purpose. To evaluate the relationship between the macular ganglion cell complex (mGCC) thickness, which is the sum of the retinal nerve fiber, ganglion cell, and inner plexiform layers, measured with a spectral-domain optical coherence tomograph and the optic nerve head topography measured with a confocal scanning las...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/914250
更新日期:2011-01-01 00:00:00
abstract:Purpose:To explore whether bandage lenses could be a safe and effective substitute for eye patch in the postoperative care for cataract surgery patients in terms of infection prevention, ocular impacts, and patient satisfaction. Methods:Patients who underwent cataract surgery were randomly divided into the eye patch g...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/1493967
更新日期:2018-05-15 00:00:00
abstract:Purpose:To investigate the correlation between decentration index (index of height decentration, IHD) automatically calculated by the Pentacam HR software and the manually calculated inferior minus superior (I-S) value. Setting:Al Watany Eye Hospital, Cairo, Egypt. Methods:In a retrospective study, history taking, cl...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/7875148
更新日期:2018-10-02 00:00:00
abstract:PURPOSE:Popular beliefs exert an impact of lunar phases on elective surgery. The aim of our study was to evaluate potential correlations between complications in cataract surgery and the phases of the moon during its passage through the zodiac and Fridays that fall on the 13th. METHODS:Patients with complications duri...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/1946527
更新日期:2017-01-01 00:00:00
abstract::Objective. To describe the clinicoradiological and histopathological findings in a case of lacrimal gland enlargement secondary to lymphomatoid granulomatosis (LG) and to review the literature. Design. Case report and systematic literature review. Methods. A 75-year-old woman presented with right ptosis. Computerised ...
journal_title:Journal of ophthalmology
pub_type:
doi:10.1155/2010/358121
更新日期:2010-01-01 00:00:00
abstract::Purpose. To determine the efficacy of 23-gauge pars plana vitrectomy (PPV) for symptomatic posterior vitreous detachment (PVD) on visual acuity (VA) and quality after multifocal intraocular lenses (IOLs). Methods. In this prospective case series, patients who developed symptomatic PVD and were not satisfied with visua...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/156910
更新日期:2015-01-01 00:00:00
abstract::Purpose. To investigate the effect of cigarette smoking on the ocular tear film. Methods. Thirty healthy young male cigarette smokers (20-38 years old) and 30 healthy age matched nonsmokers were enrolled in the study. McMonnies questionnaire, slit lamp, and PRT test were used to screen the subjects. Tear samples were ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/8154315
更新日期:2016-01-01 00:00:00
abstract::Purpose. To evaluate intraobserver and interobserver agreement in locating the scleral spur landmark (SSL) and anterior chamber angle measurements obtained using Fourier Domain Anterior Segment Optical Coherence Tomography (ASOCT) images. Methods. Two independent, masked observers (SR and AZC) identified SSLs on ASOCT...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/487309
更新日期:2012-01-01 00:00:00
abstract:Purpose:To identify and correlate age-related changes in outer retinal layers' thickness and choroidal thickness (CT) in the normal eyes using spectral-domain optical coherence tomography (SD-OCT) and to investigate factors affecting these changes. Study Design:Observational cross-sectional study. Subjects and Method...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/1698967
更新日期:2019-07-31 00:00:00