Abstract:
:Purpose. To investigate the local relationship between quantified global-flash multifocal electroretinogram (mfERG) optic nerve head component (ONHC) and visual field defects in patients with glaucoma. Methods. Thirty-nine patients with glaucoma and 30 normal controls were enrolled. The ONHC amplitude was measured from the baseline to the peak of the second positive deflection of the induced component. The ONHC amplitude was normalized by dividing ONHC amplitude by the average of seven largest ONHC amplitudes. The ONHC amplitude ratio map and ONHC deficiency map were constructed. The local relationship between the ONHC measurements and visual field defects was evaluated by calculating the overlap between the ONHC deficiency maps and visual field defect plots. Results. The mean ONHC amplitude measurements of patients with glaucoma (6.01 ± 1.91 nV/deg(2)) were significantly lower than those of the normal controls (10.29 ± 0.94 nV/deg(2)) (P < 0.001). The average overlap between the ONHC deficiency map and visual field defect plot was 71.4%. The highest overlap (75.0%) was between the ONHC ratios less than 0.5 and the total deviations less than 5%. Conclusions. The ONHC amplitude was reduced in patients with glaucoma compared to that in normal controls. Loss of the ONHC amplitude from the global-flash mfERG showed a high local agreement with visual field defects in patients with glaucoma.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Moon CH,Han J,Ohn YH,Park TKdoi
10.1155/2015/397495subject
Has Abstractpub_date
2015-01-01 00:00:00pages
397495eissn
2090-004Xissn
2090-0058journal_volume
2015pub_type
杂志文章abstract::The costs for glaucoma care are rising worldwide. The main reason is the increase of life expectancy and the increasing variety of diagnostic tests and therapeutically options by implants and devices. How can we influence the increase in costs? Does a relationship exist between the rising costs and the behavior of pat...
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doi:10.1155/2019/2746735
更新日期:2019-04-17 00:00:00
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journal_title:Journal of ophthalmology
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doi:10.1155/2016/8263832
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更新日期:2013-01-01 00:00:00
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更新日期:2017-01-01 00:00:00
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更新日期:2017-01-01 00:00:00
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更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00