Abstract：
:Keratoconus is typically diagnosed through changes at the anterior ocular surface. However, we wished to assess if macular parameter changes might also occur in these patients. We assessed posterior changes through the use of optical coherence tomography and compared to a nonkeratoconus patient group. All subjects underwent clinical examination including macular thickness measurements. The generalized estimation equation model was used to estimate the means and compare the differences in various measurements between keratoconus and nonkeratoconus patients. A total of 129 keratoconus eyes of 67 cases and 174 nonkeratoconus eyes of 87 controls were analysed. Keratoconus individuals presented with a significantly greater mean retinal thickness in the central fovea, inner, and outer macula compared to the nonkeratoconus group (p < 0.05). In addition, individuals presenting with the early signs of keratoconus had significantly greater inner and outer macular volume compared to the nonkeratoconus group (p < 0.05). This study indicates the retina appears to thicken at the fovea and macula and had increased macular volume in keratoconus individuals compared to nonkeratoconus individuals. Thus we posit that structural retinal changes exist in keratoconus eyes that are additional to those typically seen in the anterior segment.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Sahebjada S,Amirul Islam FM,Wickremasinghe S,Daniell M,Baird PNdoi
10.1155/2015/245953subject
Has Abstractpub_date
2015-01-01 00:00:00pages
245953eissn
2090-004Xissn
2090-0058journal_volume
2015pub_type
杂志文章abstract：Purpose:To analyze the results of three-year outcomes of combined epithelium-on cross-linking with femtosecond laser ICRS (cross-linking PLUS) for keratoconus management. Design:A retrospective multicenter clinical study. Methods:43 eyes of 38 patients were subjected to preoperative and postoperative UCVA, BCVA, refr...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/6907573
更新日期：2018-01-17 00:00:00
abstract：:Purpose. To examine causes as well as extent of delay in diagnosis and treatment of primary open angle glaucoma patients in a sample of Egyptians. Patients and Methods. 440 patients with primary open angle glaucoma were interviewed to evaluate delay in their diagnosis and treatment. The extent and cause of delay were ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/7012826
更新日期：2016-01-01 00:00:00
abstract：Purpose:To determine the significance of any association between intersessional changes in ocular residual astigmatism (RA) and astigmatism at corneal front (FSA) and back (BSA) surfaces following uneventful routine phacoemulsification. Methods:Astigmatism was evaluated by autorefractometry and subjective refraction a...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/7395081
更新日期：2020-07-22 00:00:00
abstract：Purpose:To evaluate neurodegeneration in patients with type 2 diabetes mellitus (DM2) without diabetic retinopathy and to assess the possible role of systemic vascular complications in retinal changes. Methods:Sixty eyes of 60 patients with DM2 and without any signs of diabetic retinopathy and 60 eyes of 60 healthy co...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/1825819
更新日期：2019-08-07 00:00:00
abstract：:The ciliary body ablation is still considered as a last resort treatment to reduce the intraocular pressure (IOP) in uncontrolled glaucoma. Several ablation techniques have been proposed over the years, all presenting a high rate of complications, nonselectivity for the target organ, and unpredictable dose-effect rela...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2017/7136275
更新日期：2017-01-01 00:00:00
abstract：:Current data permit only speculations regarding sex differences in the prevalence of infectious uveitis between women and men because uveitis case surveys do not uniformly report gender data. Differences in prevalence that are reported in the literature could relate to simple differences in the number of women and men...
journal_title：Journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1155/2014/683246
更新日期：2014-01-01 00:00:00
abstract：:Purpose. To examine the clinical implications of change in choroidal neovascularization (CNV) size on indocyanine green (ICG) angiography in subjects with idiopathic CNV undergoing bevacizumab therapy. Methods. The charts of subjects with an idiopathic CNV treated by a modified PRN regimen with intravitreal bevacizuma...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/642624
更新日期：2015-01-01 00:00:00
abstract：Purpose:The purpose of this study was to evaluate 2-year visual outcomes in patients with diabetic macular edema (DME) treated with anti-VEGF agents in a routine clinical setting. Methods:The medical records of patients treated with ranibizumab or aflibercept due to DME at the Eye Hospital, University Medical Centre L...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2020/6979758
更新日期：2020-03-16 00:00:00
abstract：Purpose:Studying the early effect of different extraocular muscle (EOM) surgeries on corneal biomechanics. Subjects and methods:This is a prospective, nonrandomized, interventional study, in which 42 eyes of 29 candidates for EOM surgery for strabismus correction at Cairo university hospitals, aged 14-37 years, were r...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/8072140
更新日期：2018-09-16 00:00:00
abstract：Purpose:To evaluate the changes in retinal vessel density and thickness after small incision lenticule extraction (SMILE) with optical coherence tomography angiography (OCTA) in myopic patients. Methods:In this prospective study, SMILE surgeries were done in 46 eyes of 24 patients with spherical equivalent (SE) more t...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/3693140
更新日期：2019-05-20 00:00:00
abstract：Purpose:The aim of this study was to assess the effects of residual anterior lens epithelial cell (LEC) removal by anterior capsule polishing on the effective lens position (ELP) and axial position stability of the intraocular lens (IOL) after cataract surgery via postoperative measurement of the anterior chamber depth...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/9704892
更新日期：2018-08-19 00:00:00
abstract：Purpose:To assess the effect of age on elevation and pachymetric Pentacam keratoconus (KC) detection indices, and the need to adjust normative values accordingly. Methods:In a retrospective study, 95 eyes of myopic normal subjects without KC were evaluated using the OCULUS Pentacam, with an age range of 17.4 to 46.8 y...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/2016564
更新日期：2018-04-22 00:00:00
abstract：Objective:In a group case series, the clinical characteristics of congenital membranous cataract in children were studied to establish a system of classification and determine the surgical method suited for each type. Methods:Children (18 eyes) with congenital membranous cataract were examined by slit lamp, ultrasound...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/2370969
更新日期：2017-01-01 00:00:00
abstract：:Purpose. To investigate the association of birth parameters with refractive status in different age groups of Caucasian children. Materials and Methods. This cross-sectional study included 564 eyes of 282 children aged 4 to 17 years. All children underwent complete ophthalmologic examination. The children were divided...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/635682
更新日期：2015-01-01 00:00:00
abstract：Purpose:Although optical coherence tomography (OCT) is essential for ophthalmologists, reading of findings requires expertise. The purpose of this study is to test deep learning with image augmentation for automated detection of chorioretinal diseases. Methods:A retina specialist diagnosed 1,200 OCT images. The diagno...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/6319581
更新日期：2019-04-09 00:00:00
abstract：Purpose:To examine and spot systemic findings commonly associated with a serious form of ocular Behcet's disease. This could potentially help ophthalmologists categorize their patients based on future risk and plan treatment accordingly. Subjects and Methods:The data of 249 patients with Behcet's disease were examined...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/9518065
更新日期：2018-04-26 00:00:00
abstract：:Purpose. To measure the chemotherapeutic effects of focal melphalan (intravitreal and subconjunctival) on tumor burden, hypoxia, and vasculature in LHBETATAG murine retinoblastoma model. Methods. LHBETATAG transgenic mice were treated with a single 1 mcg intravitreal injection of melphalan, 100 mcg subconjunctival inj...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2014/829879
更新日期：2014-01-01 00:00:00
abstract：:Purpose. To report the 12-month follow-up after big-bubble deep anterior lamellar keratoplasty (DALK) assisted by femtosecond laser that we have called IntraBubble. Methods. A 60 kHz IntraLase femtosecond laser (Abbott Medical Optics) firstly created a 30° angled intrastromal channel to insert the air injection cannul...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2012/264590
更新日期：2012-01-01 00:00:00
abstract：Purpose:To compare ocular biometry between children with type 1 diabetes mellitus (T1DM) and healthy children in China and to determine the correlation of ocular biometry with the glycosylated hemoglobin (HbA1c) level and diabetes duration. Methods:A case-control study was conducted at Children's Hospital of Fudan Uni...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2019/7216490
更新日期：2019-02-14 00:00:00
abstract：:Purpose. To validate clinically a new method for estimating the corneal power (P c ) using a variable keratometric index (n kadj) in eyes with previous laser refractive surgery. Setting. University of Alicante and Medimar International Hospital (Oftalmar), Alicante, (Spain). Design. Retrospective case series. Methods....
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/824293
更新日期：2015-01-01 00:00:00
abstract：:Genome-wide association study (GWAS) analysis identified three new susceptibility loci for PACG. In this study, we aimed to investigate whether these three loci in PLEKHA7, COL11A1, and PCMTD1-ST18 are associated with PAC and ocular biometric characteristics, such as axial length (AL), anterior chamber depth (ACD), an...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2013/641596
更新日期：2013-01-01 00:00:00
abstract：Introduction:To assess long-term efficacy of bimedial rectus tendon elongation with Tutopatch in thyroid-associated orbitopathy (TAO). Materials and Methods:Retrospective chart review of 5 patients with TAO undergoing bimedial rectus recession with Tutopatch tendon elongation between 2009 and 2015. We analyzed horizon...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/1294761
更新日期：2018-07-24 00:00:00
abstract：:Purpose. To evaluate functional and anatomical results of pars plana vitrectomy (PPV) in the retinal detachment (RD) followed by severe eye trauma. Methods. Retrospective analysis of medical records of forty-one consecutive patients treated with 23-gauge PPV due to traumatic RD. Age, gender, timing of PPV, visual acui...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/5084319
更新日期：2017-01-01 00:00:00
abstract：:The ocular surface-a continuous epithelial surface with regional specializations including the surface and glandular epithelia of the cornea, conjunctiva, and lacrimal and meibomian glands connected by the overlying tear film-plays a central role in vision. Molecular and cellular events involved in embryonic developme...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2013/103947
更新日期：2013-01-01 00:00:00
abstract：PURPOSE:To investigate the detailed distribution of corneal epithelial thickness in single sectors and its correlated characteristics in myopic eyes. METHODS:SD-OCT was used to measure the corneal epithelial thickness distribution profile. Differences of corneal epithelial thickness between different parameters and so...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2017/1018321
更新日期：2017-01-01 00:00:00
abstract：:Purpose. To describe morphology of lamellar hole-associated epiretinal proliferation (LHEP) removed from eyes with lamellar macular holes (LMH). Methods. Based on optical coherence tomography data, 10 specimens of LHEP were removed from 10 eyes with LMH during standard vitrectomy. Specimens were prepared for correlati...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/450212
更新日期：2015-01-01 00:00:00
abstract：Aim:The purpose of this study is to evaluate and compare the efficacy of 4 prostaglandin analogues (PGAs) and to determine the incidence of ocular surface disease in newly diagnosed, primary open-angle glaucoma (POAG) patients started on one of those 4 PGAs: bimatoprost (benzalkonium chloride, BAK, 0.3 mg/mL), latanopr...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2018/1319628
更新日期：2018-03-07 00:00:00
abstract：:Purpose. To examine financial and clinical work productivity outcomes associated with the use of the electronic health record (EHR). Methods. 191,360 billable clinical encounters were analyzed for 12 clinical providers over a 9-year study period during which an EHR was implemented. Main outcome measures were clinical ...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2015/329819
更新日期：2015-01-01 00:00:00
abstract：:Purpose. To examine the influence of positional misalignments on intraocular pressure (IOP) measurement with a rebound tonometer. Methods. Using the iCare rebound tonometer, IOP readings were taken from the right eye of 36 healthy subjects at the central corneal apex (CC) and compared to IOP measures using the Goldman...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2013/791084
更新日期：2013-01-01 00:00:00
abstract：:Purpose. To assess the morphology of idiopathic choroidal neovascularization (ICNV) by optical coherence tomography angiography (OCTA) and determine the therapeutic effects of intravitreal antivascular endothelial growth factor (anti-VEGF). Method. Patients with naive ICNV were assessed by spectral domain optical cohe...
journal_title：Journal of ophthalmology
pub_type： 杂志文章
doi：10.1155/2016/5608250
更新日期：2016-01-01 00:00:00
