Abstract:
:Purpose. To report a comparative prospective long-term functional analysis after Riboflavin UV A corneal cross-linking (CXL) in three different age groups of patients affected by progressive keratoconus (KC). Methods. Functional analysis comprised paediatric patients (≤18 years) included 152 eyes (29.5%); intermediate group (19-26 years) 286 eyes (55.4%), and adults (≥27 years) 78 eyes (15.1%). CXL was performed according to the Siena protocol by using the Vega CBM (Caporossi-Baiocchi-Mazzotta) X linker (CSO, Florence, Italy) at Siena University by the same authors. Pre- and post-op examinations included UCVA, BSCVA, corneal topography, and surface aberrometry (CSO Eye Top, Florence, Italy), at 48 months followup. Results. At 48 months followup paediatrics, intermediate, and adult patients showed a mean gain in UCVA of +0.2, +0.14 and +0.12 Snellen lines. BSCVA gained by a mean of +0.21, +0.2, and +0.1 Snellen lines. K(max) was reduced by a mean value of -0.9 D, -0.6 D, and -0.5 D, respectively. Coma values improved by a mean of -0.45 μm, -0.91 μm, and -0.19 μm, respectively. Treatment ensured a long-term keratoconus stabilization in over 90% of treated patients. Conclusion. According to our long-term comparative results, epithelium-off Riboflavin UV A cross-linking should be the first choice therapy of progressive KC, particularly in paediatric age and patients under 26 years.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Caporossi A,Mazzotta C,Baiocchi S,Caporossi T,Denaro Rdoi
10.1155/2011/608041subject
Has Abstractpub_date
2011-01-01 00:00:00pages
608041eissn
2090-004Xissn
2090-0058journal_volume
2011pub_type
杂志文章abstract::Purpose. This study aims to explore the safety and efficacy of a novel treatment-intense pulsed light (IPL) in MGD eyes. Methods. This study is a prospective and open label study. Forty eyes of 40 MGD patients were recruited in the study and received 4 consecutive IPL treatments on day 1, day 15, day 45, and day 75. T...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/1910694
更新日期:2016-01-01 00:00:00
abstract::Purpose. To examine the influence of positional misalignments on intraocular pressure (IOP) measurement with a rebound tonometer. Methods. Using the iCare rebound tonometer, IOP readings were taken from the right eye of 36 healthy subjects at the central corneal apex (CC) and compared to IOP measures using the Goldman...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/791084
更新日期:2013-01-01 00:00:00
abstract::Purpose. To investigate the thickness of the retinal nerve fiber layer (RNFL) and choroid in patients who have migraines in comparison to healthy controls. Methods. This study included 76 eyes and patients in the migraine group, 36 with aura (MWA group) and 40 without (MWoA group), and 38 eyes as control subjects. The...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/868967
更新日期:2015-01-01 00:00:00
abstract:Purpose:To assess the effects of the 3-month period of orthokeratology (OK) treatment on corneal sensitivity in Chinese children and adolescents. Methods:Thirty subjects wore overnight OK lenses in both eyes for 3 months and were assessed at baseline, 1 day, 1 week, 1 month, and 3 months after the treatment. Changes i...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/6185919
更新日期:2018-12-23 00:00:00
abstract:Introduction:To assess long-term efficacy of bimedial rectus tendon elongation with Tutopatch in thyroid-associated orbitopathy (TAO). Materials and Methods:Retrospective chart review of 5 patients with TAO undergoing bimedial rectus recession with Tutopatch tendon elongation between 2009 and 2015. We analyzed horizon...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/1294761
更新日期:2018-07-24 00:00:00
abstract::Diabetic retinal complications, including macular edema (DME) and proliferative diabetic retinopathy (PDR), are the leading cause of new cases of blindness among adults aged 20-74. Chronic hyperglycemia, considered the underlying cause of diabetic retinopathy, is thought to act first through violation of the pericyte-...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/209538
更新日期:2012-01-01 00:00:00
abstract::Purpose. To describe the SD-OCT findings in patients with diffuse unilateral subacute neuroretinitis (DUSN) and evaluate CRT and RNFL thickness. Methods. Patients with clinical diagnosis of DUSN who were submitted to SD-OCT were included in the study. Complete ophthalmologic examination and SD-OCT were performed. Cirr...
journal_title:Journal of ophthalmology
pub_type:
doi:10.1155/2011/285296
更新日期:2011-01-01 00:00:00
abstract:Aims:To determine the accuracy and repeatability of new software to automatically quantify GA areas associated to age-related macular degeneration (AMD) by swept-source optical coherence tomography (SS-OCT). Settings and Design. Tertiary referral hospital in Spain. Cross-sectional and noninterventional. Methods and Mat...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/8204641
更新日期:2020-08-05 00:00:00
abstract:Purpose:To evaluate the efficacy and safety of MyoRing implantation in eyes with keratoconus managed at a tertiary eye hospital in the Eastern Province of Saudi Arabia. Methods:This one-armed historical cohort study included keratoconus patients operated for MyoRing implant. The cases were assessed before and 6 months...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/2630704
更新日期:2019-08-29 00:00:00
abstract:Purpose:To evaluate a new tangential map-based nomogram versus the axial map-based nomogram for ICRS in keratoconus. Methods:A prospective case series study including 64 eyes of 64 patients who underwent ICRS implantation. Cone location was determined for each eye with two maps: the axial and the tangential. Appropria...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/3983508
更新日期:2020-02-19 00:00:00
abstract::The leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4, also called GPR48) plays a key role in multiple developmental processes, and mice lacking Lgr4 display anterior segment dysgenesis leading to early-onset glaucomatous retinal ganglion cell loss as well as defective eyelid formation. This paper will...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/987494
更新日期:2013-01-01 00:00:00
abstract::Purpose. To evaluate the relationship between the macular ganglion cell complex (mGCC) thickness, which is the sum of the retinal nerve fiber, ganglion cell, and inner plexiform layers, measured with a spectral-domain optical coherence tomograph and the optic nerve head topography measured with a confocal scanning las...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/914250
更新日期:2011-01-01 00:00:00
abstract::Purpose. To evaluate visual and safety outcomes of 23-gauge (G) pars plana vitrectomy (PPV) with application of perfluorocarbon liquid (PFCL) for intraoperative protection of the macula during intraocular foreign body (IOFB) removal. Methods. Retrospective study of 42 patients who underwent 23 G PPV for IOFB removal f...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/6232151
更新日期:2017-01-01 00:00:00
abstract:Background:The aim of this meta-analysis was to compare morphological and functional outcomes between vitrectomy with the inverted internal limiting membrane (ILM) flap technique and vitrectomy with internal limiting membrane peeling in highly myopic eyes with macular hole- (MH-) induced retinal detachment (MHRD). Met...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2020/2374650
更新日期:2020-08-24 00:00:00
abstract:PURPOSE:To evaluate sequential changes in choroidal thickness at the affected area in patients with acute zonal occult outer retinopathy (AZOOR). METHODS:This retrospective observational case series included 14 affected eyes and 6 unaffected fellow eyes from 10 AZOOR patients with impaired macular area. Using enhanced...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/2371032
更新日期:2017-01-01 00:00:00
abstract::Purpose. To compare the surgically induced astigmatism from clear corneal and square posterior limbal incisions at the time of cataract surgery. Methods. Surgically induced astigmatism was calculated for a set of eyes after cataract surgery using a temporal 2.2 mm square posterior limbal incision. Results were compare...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/243170
更新日期:2011-01-01 00:00:00
abstract::The ocular surface-a continuous epithelial surface with regional specializations including the surface and glandular epithelia of the cornea, conjunctiva, and lacrimal and meibomian glands connected by the overlying tear film-plays a central role in vision. Molecular and cellular events involved in embryonic developme...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/103947
更新日期:2013-01-01 00:00:00
abstract:Objective:In a group case series, the clinical characteristics of congenital membranous cataract in children were studied to establish a system of classification and determine the surgical method suited for each type. Methods:Children (18 eyes) with congenital membranous cataract were examined by slit lamp, ultrasound...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/2370969
更新日期:2017-01-01 00:00:00
abstract::Fifty-two eyes of 52 patients with treatment-naïve macular edema associated with perfused branch retinal vein occlusion were retrospectively reviewed. Twenty-seven cases received PRN intravitreal bevacizumab, and 25 cases were treated by PRN intravitreal aflibercept with monthly follow-ups for 12 months. Both afliberc...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/8421940
更新日期:2016-01-01 00:00:00
abstract::Purpose. To report the 12-month follow-up after big-bubble deep anterior lamellar keratoplasty (DALK) assisted by femtosecond laser that we have called IntraBubble. Methods. A 60 kHz IntraLase femtosecond laser (Abbott Medical Optics) firstly created a 30° angled intrastromal channel to insert the air injection cannul...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/264590
更新日期:2012-01-01 00:00:00
abstract::The new type implantable Collamer lens with a central hole (V4c-ICL) is widely used to treat myopia. However, halos occur in some patients after surgery. The aim is to evaluate the effect of V4c-ICL implantation on vision-related daily activities. This retrospective study included 42 patients. Uncorrected visual acuit...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/5717932
更新日期:2016-01-01 00:00:00
abstract::Keratoconus is typically diagnosed through changes at the anterior ocular surface. However, we wished to assess if macular parameter changes might also occur in these patients. We assessed posterior changes through the use of optical coherence tomography and compared to a nonkeratoconus patient group. All subjects und...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/245953
更新日期:2015-01-01 00:00:00
abstract::Primary congenital glaucoma is a worldwide diagnostic and therapeutic challenge. Although medical management is often a temporizing measure, early surgical intervention is the definitive treatment. As the abundance of surgical treatment options continues to expand, the authors will compare and contrast the available o...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/612708
更新日期:2013-01-01 00:00:00
abstract:Purpose:To evaluate the changes in retinal vessel density and thickness after small incision lenticule extraction (SMILE) with optical coherence tomography angiography (OCTA) in myopic patients. Methods:In this prospective study, SMILE surgeries were done in 46 eyes of 24 patients with spherical equivalent (SE) more t...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/3693140
更新日期:2019-05-20 00:00:00
abstract:Purpose:Activating transcription factor 4 (ATF4) is induced by various stressors. Here, we investigated the expression of ATF4 in the host inflammatory response to Aspergillus fumigatus (A. fumigatus) keratitis. Methods:A. fumigatus keratitis mouse models developed by intrastromal injection as well as corneal epitheli...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/5830202
更新日期:2018-12-13 00:00:00
abstract::This study is for identifying systemic factors correlating with intraocular levels of interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF) in diabetic retinopathy. Forty-two consecutive patients undergoing pars plana vitrectomy (PPV) for PDR were included in this cross-sectional study. The aqueous humor ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/4831967
更新日期:2019-07-17 00:00:00
abstract::Purpose. To examine financial and clinical work productivity outcomes associated with the use of the electronic health record (EHR). Methods. 191,360 billable clinical encounters were analyzed for 12 clinical providers over a 9-year study period during which an EHR was implemented. Main outcome measures were clinical ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/329819
更新日期:2015-01-01 00:00:00
abstract:Purpose:To identify and correlate age-related changes in outer retinal layers' thickness and choroidal thickness (CT) in the normal eyes using spectral-domain optical coherence tomography (SD-OCT) and to investigate factors affecting these changes. Study Design:Observational cross-sectional study. Subjects and Method...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/1698967
更新日期:2019-07-31 00:00:00
abstract::Background. The aim of this study is to investigate the ocular thermographic profiles in age-related macular degeneration (AMD) eyes and age-matched controls to detect possible hemodynamic abnormalities, which could be involved in the pathogenesis of the disease. Methods. 32 eyes with early AMD, 37 eyes with atrophic ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/281010
更新日期:2014-01-01 00:00:00
abstract:Objective:To determine whether accommodation induced by reading alters intraocular pressure (IOP) in healthy, young, emmetropic adults and to document the duration and magnitude of this effect. Design:Cross-sectional study. Participants. Fifteen healthy, emmetropic young adults. Methods:Subjects performed 20 minutes ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/1352434
更新日期:2020-01-28 00:00:00