Abstract:
:Purpose. To evaluate the relationship between the macular ganglion cell complex (mGCC) thickness, which is the sum of the retinal nerve fiber, ganglion cell, and inner plexiform layers, measured with a spectral-domain optical coherence tomograph and the optic nerve head topography measured with a confocal scanning laser ophthalmoscope in glaucomatous eyes with visual field defects localized predominantly to either hemifield. Materials and Methods. The correlation between the mGCC thickness in hemispheres corresponding to hemifields with and without defects (damaged and intact hemispheres, respectively) and the optic nerve head topography corresponding to the respective hemispheres was evaluated in 18 glaucomatous eyes. Results. The mGCC thickness was significantly correlated with the rim volume, mean retinal nerve fiber layer thickness, and cross-sectional area of the retinal nerve fiber layer in both the intact and the damaged hemispheres (P < .05). Discussion. For detecting very early glaucomatous damage of the optic nerve, changes in the thicknesses of the inner retina in the macular area and peripapillary RNFL as well as rim volume changes in the optic nerve head are target parameters that should be carefully monitored.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Takagi ST,Kita Y,Takeyama A,Tomita Gdoi
10.1155/2011/914250subject
Has Abstractpub_date
2011-01-01 00:00:00pages
914250eissn
2090-004Xissn
2090-0058journal_volume
2011pub_type
杂志文章abstract:Background:Endoplasmic reticulum stress (ERS) in the retinal Müller cells is a key factor contributing to the retinal inflammation and vascular leakage in diabetic retinopathy (DR). This study was to investigate the underlying mechanisms through which the 3 main unfolded protein response (UPR) pathways regulate ERS and...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/9028483
更新日期:2019-02-24 00:00:00
abstract:PURPOSE:To investigate the detailed distribution of corneal epithelial thickness in single sectors and its correlated characteristics in myopic eyes. METHODS:SD-OCT was used to measure the corneal epithelial thickness distribution profile. Differences of corneal epithelial thickness between different parameters and so...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/1018321
更新日期:2017-01-01 00:00:00
abstract::Purpose. To examine the influence of positional misalignments on intraocular pressure (IOP) measurement with a rebound tonometer. Methods. Using the iCare rebound tonometer, IOP readings were taken from the right eye of 36 healthy subjects at the central corneal apex (CC) and compared to IOP measures using the Goldman...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/791084
更新日期:2013-01-01 00:00:00
abstract::Background. We aimed to evaluate the association between maternal smoking and the occurrence of childhood refractive error and amblyopia. Methods. Relevant articles were identified from PubMed and EMBASE up to May 2015. Combined odds ratio (OR) corresponding with its 95% confidence interval (CI) was calculated to eval...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/8263832
更新日期:2016-01-01 00:00:00
abstract:Purpose:To ascertain wet AMD (wAMD) management patterns in Spain. Methods:A two-round Delphi study conducted through a questionnaire-based survey designed from literature review and validated by an independent Steering Committee. Results:Forty-nine retina specialists experienced in wAMD participated by answering the ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/9821509
更新日期:2019-09-30 00:00:00
abstract::Purpose. To investigate the effect of cigarette smoking on the ocular tear film. Methods. Thirty healthy young male cigarette smokers (20-38 years old) and 30 healthy age matched nonsmokers were enrolled in the study. McMonnies questionnaire, slit lamp, and PRT test were used to screen the subjects. Tear samples were ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/8154315
更新日期:2016-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2016/3690140.]. ...
journal_title:Journal of ophthalmology
pub_type: 已发布勘误
doi:10.1155/2019/6212745
更新日期:2019-06-11 00:00:00
abstract::Purpose. To evaluate visual and safety outcomes of 23-gauge (G) pars plana vitrectomy (PPV) with application of perfluorocarbon liquid (PFCL) for intraoperative protection of the macula during intraocular foreign body (IOFB) removal. Methods. Retrospective study of 42 patients who underwent 23 G PPV for IOFB removal f...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/6232151
更新日期:2017-01-01 00:00:00
abstract::Purpose. To compare fluorescein angiography (FA) and optical coherence tomography angiography (OCTA) images of foveal avascular zone (FAZ) in patients with diabetic retinopathy (DR) with and without diabetic macular ischemia (DMI). Methods. The Wilcoxon signed-rank test was used to compare area measurements and p valu...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/3989310
更新日期:2016-01-01 00:00:00
abstract::The ciliary body ablation is still considered as a last resort treatment to reduce the intraocular pressure (IOP) in uncontrolled glaucoma. Several ablation techniques have been proposed over the years, all presenting a high rate of complications, nonselectivity for the target organ, and unpredictable dose-effect rela...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2017/7136275
更新日期:2017-01-01 00:00:00
abstract::Purpose. We report the effect of isotretinoin on corneal topography, corneal thickness, and biomechanical parameters in patients with acne vulgaris. Method. Fifty-four eyes of 54 patients who received oral isotretinoin for treatment of acne vulgaris were evaluated. All patients underwent a corneal topographical evalua...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/701361
更新日期:2014-01-01 00:00:00
abstract:Purpose:The aim of this work was to describe the ultrastructure and behavior of peeled internal limiting membrane (ILM) in macular hole (MH) surgery. Methods:Seven patients with MH were included, and vitrectomy with ILM peeling was performed in all patients. The ILM inverted flap technique was used. Two other flaps of...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/1345683
更新日期:2019-05-02 00:00:00
abstract::Purpose. To evaluate interobserver, intervisit, and interinstrument agreements for gonioscopy and Fourier domain anterior segment optical coherence tomography (FD ASOCT) for classifying open and narrow angle eyes. Methods. Eighty-six eyes with open or narrow anterior chamber angles were included. The superior angle wa...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/1727039
更新日期:2016-01-01 00:00:00
abstract:Purpose:The iStent provides a direct pathway for aqueous outflow from the anterior chamber to Schlemm's canal in patients with open-angle glaucoma (OAG). We performed a meta-analysis to evaluate the effectiveness of iStent as a standalone operation in patients with OAG in reducing the intraocular pressure (IOP) and the...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2020/8754730
更新日期:2020-05-24 00:00:00
abstract::Aim. The aim of this study was to determine the intra- and interobserver variability of two Scheimpflug based camera systems, Pentacam and Sirius. In addition, the comparability of the measurements was tested in healthy subjects, subjects with regular astigmatism, and keratoconus patients. Methods. Intra- and interobs...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/315281
更新日期:2015-01-01 00:00:00
abstract::The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration or apoptosis patterns of photoreceptors are still unclear in rd11 mi...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/9721362
更新日期:2017-01-01 00:00:00
abstract::Purpose. The aim of this study is to investigate the etiology and the clinical, microbiological, histopathological, and radiological findings of acquired dacryocystoceles. Methods. In this retrospective study, we reviewed the clinical records of 10 eyes of 8 patients with dacryocystoceles who underwent external dacryo...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/396782
更新日期:2014-01-01 00:00:00
abstract:Purpose:The purpose of this meta-analysis was to assess the percent reduction in the intraocular pressure (IOP) after argon laser peripheral iridoplasty (ALPI) and systemic medical therapy in patients with acute primary angle closure (APAC). Methods:We searched a number of electronic databases, including MEDLINE, EMBA...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2019/7697416
更新日期:2019-05-02 00:00:00
abstract::Purpose. To determine the efficacy of povidone-iodine (P-I) prophylaxis for ophthalmia neonatorum (ON) in Angola and to document maternal prevalence and mother-to-child transmission rates. Methods. Endocervical samples from mothers (n = 317) and newborn conjunctival smears (n = 245) were analysed by multiplex polymera...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/326526
更新日期:2015-01-01 00:00:00
abstract:Purpose:To compare the outcomes of Ex-PRESS glaucoma filtration device and transscleral cyclophotocoagulation (TSCP) in the management of neovascular glaucoma (NVG). Patients and Methods. A total of 30 eyes (12 express shunts and 18 TSCP) of 28 patients were included. The eyes had NVG with intraocular pressure (IOP) mo...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/3781249
更新日期:2020-05-17 00:00:00
abstract::Genome-wide association study (GWAS) analysis identified three new susceptibility loci for PACG. In this study, we aimed to investigate whether these three loci in PLEKHA7, COL11A1, and PCMTD1-ST18 are associated with PAC and ocular biometric characteristics, such as axial length (AL), anterior chamber depth (ACD), an...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/641596
更新日期:2013-01-01 00:00:00
abstract:Purpose:To explore whether bandage lenses could be a safe and effective substitute for eye patch in the postoperative care for cataract surgery patients in terms of infection prevention, ocular impacts, and patient satisfaction. Methods:Patients who underwent cataract surgery were randomly divided into the eye patch g...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/1493967
更新日期:2018-05-15 00:00:00
abstract::Age-related macular degeneration (AMD) is one of the main socioeconomical health issues worldwide. AMD has a multifactorial etiology with a variety of risk factors. Smoking is the most important modifiable risk factor for AMD development and progression. The present review summarizes the epidemiological studies evalua...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2013/895147
更新日期:2013-01-01 00:00:00
abstract:Purpose:The purpose of this study was to evaluate 2-year visual outcomes in patients with diabetic macular edema (DME) treated with anti-VEGF agents in a routine clinical setting. Methods:The medical records of patients treated with ranibizumab or aflibercept due to DME at the Eye Hospital, University Medical Centre L...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/6979758
更新日期:2020-03-16 00:00:00
abstract:Purpose:To evaluate the effect of corneal cap thickness on visual acuity and corneal biomechanics in small incision lenticule extraction (SMILE) for the treatment of myopia. Methods:Forty eyes of 20 patients undergoing SMILE for the treatment of myopia were enrolled in this prospective controlled study. The patients w...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/6040873
更新日期:2018-06-28 00:00:00
abstract::Purpose. To describe morphology of lamellar hole-associated epiretinal proliferation (LHEP) removed from eyes with lamellar macular holes (LMH). Methods. Based on optical coherence tomography data, 10 specimens of LHEP were removed from 10 eyes with LMH during standard vitrectomy. Specimens were prepared for correlati...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/450212
更新日期:2015-01-01 00:00:00
abstract::We established a chronic dacryocystitis model by injecting of 0.05, 0.1, and 0.15 ml self-curing resin via the lacrimal punctum in rabbits. Animals were randomized into four groups (n = 11 animals/group). The control group received 0.15 ml normal saline. Within three months postinjection, epiphora and eye discharge we...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/3438041
更新日期:2017-01-01 00:00:00
abstract::Diabetic retinal complications, including macular edema (DME) and proliferative diabetic retinopathy (PDR), are the leading cause of new cases of blindness among adults aged 20-74. Chronic hyperglycemia, considered the underlying cause of diabetic retinopathy, is thought to act first through violation of the pericyte-...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/209538
更新日期:2012-01-01 00:00:00
abstract:Objective:In a group case series, the clinical characteristics of congenital membranous cataract in children were studied to establish a system of classification and determine the surgical method suited for each type. Methods:Children (18 eyes) with congenital membranous cataract were examined by slit lamp, ultrasound...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/2370969
更新日期:2017-01-01 00:00:00
abstract:Background:Bardet-Biedl syndrome (BBS) is a rare multisystem developmental disorder. In this study, we report the genetic causes and clinical manifestations in two Chinese families with BBS. Materials and Methods:Two families were recruited in this study. Family A was a four-generation family with four affected and 15...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2021/6751857
更新日期:2021-01-06 00:00:00