Abstract:
:Purpose. To describe morphology of lamellar hole-associated epiretinal proliferation (LHEP) removed from eyes with lamellar macular holes (LMH). Methods. Based on optical coherence tomography data, 10 specimens of LHEP were removed from 10 eyes with LMH during standard vitrectomy. Specimens were prepared for correlative light and electron microscopy (CLEM) using an immunonanogold particle of 1.4 nm diameter that was combined with a fluorescein moiety, both having been attached to a single antibody fragment. As primary antibodies, we used antiglial fibrillary acidic protein (GFAP), anti-CD45, anti-CD64, anti-α-smooth muscle actin (α-SMA), and anticollagen type I and type II. Results. In LHEP, GFAP-positive cells possess ultrastructural characteristics of fibroblasts and hyalocytes. They represent the major cell types and were densely packed in cell agglomerations on vitreous collagen strands. Epiretinal cells of LHEP rarely demonstrated contractive properties as α-SMA-positive myofibroblasts were an infrequent finding. Conclusion. CLEM indicates that epiretinal cells in LHEP might originate from the vitreous and that remodelling processes of vitreous collagen may play an important role in pathogenesis of eyes with LMH.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Compera D,Entchev E,Haritoglou C,Mayer WJ,Hagenau F,Ziada J,Kampik A,Schumann RGdoi
10.1155/2015/450212subject
Has Abstractpub_date
2015-01-01 00:00:00pages
450212eissn
2090-004Xissn
2090-0058journal_volume
2015pub_type
杂志文章abstract:Purpose:To evaluate the efficacy and safety of MyoRing implantation in eyes with keratoconus managed at a tertiary eye hospital in the Eastern Province of Saudi Arabia. Methods:This one-armed historical cohort study included keratoconus patients operated for MyoRing implant. The cases were assessed before and 6 months...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/2630704
更新日期:2019-08-29 00:00:00
abstract::Objective. To describe the clinicoradiological and histopathological findings in a case of lacrimal gland enlargement secondary to lymphomatoid granulomatosis (LG) and to review the literature. Design. Case report and systematic literature review. Methods. A 75-year-old woman presented with right ptosis. Computerised ...
journal_title:Journal of ophthalmology
pub_type:
doi:10.1155/2010/358121
更新日期:2010-01-01 00:00:00
abstract::Purpose. To review the newer treatments for bacterial keratitis. Data Sources. PubMed literature search up to April 2012. Study Selection. Key words used for literature search: "infectious keratitis", "microbial keratitis", "infective keratitis", "new treatments for infectious keratitis", "fourth generation fluoroquin...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/831502
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To evaluate the static measurement of the accommodative stimulus-response curve with emoji symbols. METHODS:The accommodative stimulus-response curve was measured in 18 subjects using a Hartmann-Shack sensor to obtain the objective accommodative response from the Zernike defocus term. Measurements were acquire...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/4165706
更新日期:2017-01-01 00:00:00
abstract::Familial exudative vitreoretinopathy (FEVR) is a hereditary ocular disorder characterized by incomplete vascularization/abnormality of peripheral retina. Four of the identified disease-causing genes of FEVR were NDP, FZD4, LRP5, and TSPAN12, the protein coded by which were the components of the Norrin/β-catenin signal...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2019/5782536
更新日期:2019-11-16 00:00:00
abstract::Aims. Increasing evidence shows that imbalanced suppressive drive prior to binocular combination may be the key factor in amblyopia. We described a novel binocular approach, interocular shift of visual attention (ISVA), for treatment of amblyopia in adult patients. Methods. Visual stimuli were presented anaglyphically...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/615213
更新日期:2014-01-01 00:00:00
abstract::This study is for identifying systemic factors correlating with intraocular levels of interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF) in diabetic retinopathy. Forty-two consecutive patients undergoing pars plana vitrectomy (PPV) for PDR were included in this cross-sectional study. The aqueous humor ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/4831967
更新日期:2019-07-17 00:00:00
abstract:Background:Uveal melanoma (UM) is the most common primary intraocular tumor in adults and arises from the uvea. Marital status was a vital factor among physical conditions and social networks of cancer patients. Our study aimed to evaluate the impact of marital status on the outcomes among patients with UM. Methods:Pa...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/7012940
更新日期:2020-12-04 00:00:00
abstract:Objective:To calculate the Q values from the human anterior corneal surface with the tangential radius of curvature and analyze its distribution characteristics in different age and refractive status groups. Methods:Tangential power maps of the anterior cornea from Orbscan II were acquired for 201 subjects' right eyes...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/7263564
更新日期:2018-04-17 00:00:00
abstract::Purpose. To measure central corneal thickness (CCT) in patients with history of nonarteritic anterior ischemic optic neuropathy (NAION). Patients and Methods. Patients older than 40 years with a history of NAION (group 1) were prospectively evaluated including full eye examination and central corneal thickness (CCT) p...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/904373
更新日期:2014-01-01 00:00:00
abstract:Purpose:To evaluate the difference in the repeatability of automated superficial retinal vessel density and foveal avascular zone (FAZ) metrics according to the measurement area of optical coherence tomography angiography (OCTA). Methods:A total of 127 normal eyes from 127 healthy subjects were included. Macular angio...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/5686894
更新日期:2020-04-17 00:00:00
abstract::Purpose. To investigate the agreement between morphometric optic nerve head parameters assessed with the confocal laser ophthalmoscope HRT III and the stereoscopic fundus camera Kowa nonmyd WX3D retrospectively. Methods. Morphometric optic nerve head parameters of 40 eyes of 40 patients with primary open angle glaucom...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/4764857
更新日期:2016-01-01 00:00:00
abstract:Purpose:To investigate the association between regional solar radiation and myopia occurrence in South Korean children. Materials and Methods:A population-based cross-sectional study using data of 1218 children aged 7-9 years from the Korea National Health and Nutritional Examination Survey was conducted from January ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/7643850
更新日期:2019-06-10 00:00:00
abstract:Background:Bardet-Biedl syndrome (BBS) is a rare multisystem developmental disorder. In this study, we report the genetic causes and clinical manifestations in two Chinese families with BBS. Materials and Methods:Two families were recruited in this study. Family A was a four-generation family with four affected and 15...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2021/6751857
更新日期:2021-01-06 00:00:00
abstract:PURPOSE:Popular beliefs exert an impact of lunar phases on elective surgery. The aim of our study was to evaluate potential correlations between complications in cataract surgery and the phases of the moon during its passage through the zodiac and Fridays that fall on the 13th. METHODS:Patients with complications duri...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/1946527
更新日期:2017-01-01 00:00:00
abstract::Purpose. This study investigated the effects of oral propolis on the progression of galactose-induced sugar cataracts in rats and the in vitro effects of propolis on high-glucose-induced reactive oxygen species (ROS) and cell death in cultured rat lens cells (RLECs). Methods. Galactose-fed rats and RLECs cultured in h...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/1917093
更新日期:2016-01-01 00:00:00
abstract:Purpose:Evaluation of the indications, anatomical and functional results, and complications of total penetrating keratoplasty (TPK) in disorders involving whole cornea. Materials and Methods:We analyzed outcomes of the surgical treatment of 47 eyes of 46 patients that underwent TPK. Indications were infectious keratit...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/9580292
更新日期:2018-04-19 00:00:00
abstract:Purpose:To compare the outcomes of Ex-PRESS glaucoma filtration device and transscleral cyclophotocoagulation (TSCP) in the management of neovascular glaucoma (NVG). Patients and Methods. A total of 30 eyes (12 express shunts and 18 TSCP) of 28 patients were included. The eyes had NVG with intraocular pressure (IOP) mo...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/3781249
更新日期:2020-05-17 00:00:00
abstract::The aim of this study was to assess the oxidative stress status in eyes affected by synchysis scintillans and to compare it to vitreoretinal disorders without synchysis scintillans. Human aqueous and vitreous humors were obtained during vitrectomy from thirty-seven otherwise healthy patients that were randomly chosen ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/7231015
更新日期:2019-10-30 00:00:00
abstract:Purpose:The aim of this work was to describe the ultrastructure and behavior of peeled internal limiting membrane (ILM) in macular hole (MH) surgery. Methods:Seven patients with MH were included, and vitrectomy with ILM peeling was performed in all patients. The ILM inverted flap technique was used. Two other flaps of...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/1345683
更新日期:2019-05-02 00:00:00
abstract::Introduction. Retinoblastoma is the most common primary intraocular neoplasm in children. With the advances in medicine, the armamentarium of available treatment modalities has grown. Intraarterial chemotherapy is a relatively new treatment method with promising outcomes. The purpose of this literature review is to ev...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2020/3638410
更新日期:2020-01-24 00:00:00
abstract::Keratoconus is typically diagnosed through changes at the anterior ocular surface. However, we wished to assess if macular parameter changes might also occur in these patients. We assessed posterior changes through the use of optical coherence tomography and compared to a nonkeratoconus patient group. All subjects und...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/245953
更新日期:2015-01-01 00:00:00
abstract:Purpose:To assess the effects of the 3-month period of orthokeratology (OK) treatment on corneal sensitivity in Chinese children and adolescents. Methods:Thirty subjects wore overnight OK lenses in both eyes for 3 months and were assessed at baseline, 1 day, 1 week, 1 month, and 3 months after the treatment. Changes i...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/6185919
更新日期:2018-12-23 00:00:00
abstract:Objective:This study aims to describe the clinical manifestations and outcomes in a cohort of older Chinese patients. Method:A retrospective study of patients aged ≥ 45 years who had a first episode of optic neuritis (ON) between May 2008 and November 2012. Clinical features at onset and last follow-up were analyzed w...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/3458356
更新日期:2017-01-01 00:00:00
abstract::Purpose. To evaluate the relationship between the macular ganglion cell complex (mGCC) thickness, which is the sum of the retinal nerve fiber, ganglion cell, and inner plexiform layers, measured with a spectral-domain optical coherence tomograph and the optic nerve head topography measured with a confocal scanning las...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/914250
更新日期:2011-01-01 00:00:00
abstract:Purpose:To evaluate the outcomes of femtosecond laser-assisted implantation of a 355-degree intracorneal ring (ICR) (Keraring) in patients with keratoconus in the three-year follow-up. Setting:Future Femtolaser Center, Sohag, Egypt. Design:Prospective interventional case series. Patients and Methods:A prospective ca...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/6783181
更新日期:2019-10-09 00:00:00
abstract::Purpose. To investigate the thickness of the retinal nerve fiber layer (RNFL) and choroid in patients who have migraines in comparison to healthy controls. Methods. This study included 76 eyes and patients in the migraine group, 36 with aura (MWA group) and 40 without (MWoA group), and 38 eyes as control subjects. The...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/868967
更新日期:2015-01-01 00:00:00
abstract::The functional visual acuity test which is the average of the visual acuities measured during a specific time frame (standard, 60 seconds) has been used recently to assess the visual function in various conditions. The availability of a shorter version of the functional visual acuity test promises to be patient friend...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/8950418
更新日期:2019-09-10 00:00:00
abstract:Purpose:To compare two calculators for toric intraocular lens (IOL) calculation and to evaluate the prediction of refractive outcome. Methods:Sixty-four eyes of forty-five patients underwent cataract surgery followed by implantation of a toric intraocular lens (Zeiss Torbi 709 M) calculated by a standard industry calc...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/2840246
更新日期:2018-01-10 00:00:00
abstract::Purpose. To compare the surgically induced astigmatism from clear corneal and square posterior limbal incisions at the time of cataract surgery. Methods. Surgically induced astigmatism was calculated for a set of eyes after cataract surgery using a temporal 2.2 mm square posterior limbal incision. Results were compare...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/243170
更新日期:2011-01-01 00:00:00