Morphology of Peeled Internal Limiting Membrane in Macular Hole Surgery.

Abstract:

Purpose:The aim of this work was to describe the ultrastructure and behavior of peeled internal limiting membrane (ILM) in macular hole (MH) surgery. Methods:Seven patients with MH were included, and vitrectomy with ILM peeling was performed in all patients. The ILM inverted flap technique was used. Two other flaps of ILM of the same patient were collected and studied using light and transmission electron microscopy (TEM). ILM cell type, distribution, and morphology were analyzed, and the proliferation or fusion potential of the ILM interface was evaluated. Results:ILM vitreous sides in apposition showed signs of proliferative fibrotic activity, producing a basal membrane that merges ILM sides. Conclusions:Epiretinal cells in ILM show proliferative capacity, with formation of microfibrils between adjacent sides of the ILM, which may explain adherence of ILM flaps to the hole border, contributing to closure of the hole in MH surgery. This trail is registered with NCT03799575.

journal_name

J Ophthalmol

journal_title

Journal of ophthalmology

authors

Faria MY,Sousa DC,Almeida BC,Pinto AL,Ferreira NP

doi

10.1155/2019/1345683

subject

Has Abstract

pub_date

2019-05-02 00:00:00

pages

1345683

eissn

2090-004X

issn

2090-0058

journal_volume

2019

pub_type

杂志文章
  • Novel Technique of Pneumatic Posterior Capsulorhexis for Treatment and Prevention of Posterior Capsular Opacification.

    abstract:Purpose:To evaluate a new technique of posterior capsulorhexis using air support to treat primary posterior capsular opacification (PCO) during cataract extraction surgery or to prevent postoperative PCO. Setting:(1) Ophthalmology department, Faculty of Medicine, Minia University, 61519, El-Minia, Egypt. (2) Security ...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/3174709

    authors: Eid AM,Abd-Elhamid Mehany Elwan S,Sabry AM,Moharram HM,Bakhsh AM

    更新日期:2019-12-21 00:00:00

  • Three-Year Outcomes of Cross-Linking PLUS (Combined Cross-Linking with Femtosecond Laser Intracorneal Ring Segments Implantation) for Management of Keratoconus.

    abstract:Purpose:To analyze the results of three-year outcomes of combined epithelium-on cross-linking with femtosecond laser ICRS (cross-linking PLUS) for keratoconus management. Design:A retrospective multicenter clinical study. Methods:43 eyes of 38 patients were subjected to preoperative and postoperative UCVA, BCVA, refr...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2018/6907573

    authors: Saleem MIH,Ibrahim Elzembely HA,AboZaid MA,Elagouz M,Saeed AM,Mohammed OA,Kamel AG

    更新日期:2018-01-17 00:00:00

  • Ocular surface temperature in age-related macular degeneration.

    abstract::Background. The aim of this study is to investigate the ocular thermographic profiles in age-related macular degeneration (AMD) eyes and age-matched controls to detect possible hemodynamic abnormalities, which could be involved in the pathogenesis of the disease. Methods. 32 eyes with early AMD, 37 eyes with atrophic ...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2014/281010

    authors: Sodi A,Matteoli S,Giacomelli G,Finocchio L,Corvi A,Menchini U

    更新日期:2014-01-01 00:00:00

  • Shortened Measurement Time of Functional Visual Acuity for Screening Visual Function.

    abstract::The functional visual acuity test which is the average of the visual acuities measured during a specific time frame (standard, 60 seconds) has been used recently to assess the visual function in various conditions. The availability of a shorter version of the functional visual acuity test promises to be patient friend...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/8950418

    authors: Hidaka Y,Masui S,Nishi Y,Ayaki M,Kaido M,Mimura M,Tsubota K,Negishi K

    更新日期:2019-09-10 00:00:00

  • Oxidative Stress, Lipid Peroxidation, and Loss of Hyaluronic Acid in the Human Vitreous Affected by Synchysis Scintillans.

    abstract::The aim of this study was to assess the oxidative stress status in eyes affected by synchysis scintillans and to compare it to vitreoretinal disorders without synchysis scintillans. Human aqueous and vitreous humors were obtained during vitrectomy from thirty-seven otherwise healthy patients that were randomly chosen ...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/7231015

    authors: Bergandi L,Skorokhod OA,La Grotta R,Schwarzer E,Nuzzi R

    更新日期:2019-10-30 00:00:00

  • Spectral domain optical coherence tomography in diffuse unilateral subacute neuroretinitis.

    abstract::Purpose. To describe the SD-OCT findings in patients with diffuse unilateral subacute neuroretinitis (DUSN) and evaluate CRT and RNFL thickness. Methods. Patients with clinical diagnosis of DUSN who were submitted to SD-OCT were included in the study. Complete ophthalmologic examination and SD-OCT were performed. Cirr...

    journal_title:Journal of ophthalmology

    pub_type:

    doi:10.1155/2011/285296

    authors: Garcia Filho CA,Soares AC,Penha FM,Garcia CA

    更新日期:2011-01-01 00:00:00

  • Fundus Autofluorescence in Lamellar Macular Holes and Pseudoholes: A Review.

    abstract::Macular pseudoholes (MPHs) and lamellar macular holes (LMHs) have been recently defined according to spectral domain optical coherence tomography (SD-OCT) criteria. A major feature for differentiating an MPH from an LMH remains the loss of foveal tissue. The anatomy of the foveola is peculiar with the macular pigment ...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1155/2019/4948212

    authors: Bottoni F

    更新日期:2019-02-10 00:00:00

  • Cyanin Chloride Inhibits Hyperbaric Pressure-Induced Decrease of Intracellular Glutamate-Aspartate Transporter in Rat Retinal Müller Cells.

    abstract:Purpose:Glaucoma is the leading cause of irreversible blindness throughout the world. The pathogenesis of glaucoma is complex, and neuroprotection is a crucial aspect of therapy. High concentrations of extracellular glutamate are toxic to the optic nerve. The glutamate-aspartate transporter (GLAST) in retinal Müller ce...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2018/6128470

    authors: Chen X,Wang Y,Han F,Ke M

    更新日期:2018-10-31 00:00:00

  • Accommodative Stimulus-Response Curve with Emoji Symbols.

    abstract:PURPOSE:To evaluate the static measurement of the accommodative stimulus-response curve with emoji symbols. METHODS:The accommodative stimulus-response curve was measured in 18 subjects using a Hartmann-Shack sensor to obtain the objective accommodative response from the Zernike defocus term. Measurements were acquire...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2017/4165706

    authors: Montés-Micó R,Esteve Taboada JJ,Bernal-Molina P,Ferrer-Blasco T

    更新日期:2017-01-01 00:00:00

  • Clinical, radiological, microbiological, and histopathological aspects of acquired dacryocystoceles.

    abstract::Purpose. The aim of this study is to investigate the etiology and the clinical, microbiological, histopathological, and radiological findings of acquired dacryocystoceles. Methods. In this retrospective study, we reviewed the clinical records of 10 eyes of 8 patients with dacryocystoceles who underwent external dacryo...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2014/396782

    authors: Sendul SY,Cinar S,Cağatay HH,Demir M,Dirim B,Guven D

    更新日期:2014-01-01 00:00:00

  • Outcomes of MyoRing Implantation in Eyes with Keratoconus in the Eastern Province of Saudi Arabia: "A Single-Arm Cohort Study".

    abstract:Purpose:To evaluate the efficacy and safety of MyoRing implantation in eyes with keratoconus managed at a tertiary eye hospital in the Eastern Province of Saudi Arabia. Methods:This one-armed historical cohort study included keratoconus patients operated for MyoRing implant. The cases were assessed before and 6 months...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/2630704

    authors: Alshammari YS,Al Somali AI

    更新日期:2019-08-29 00:00:00

  • Risk of Ischemic Stroke, Hemorrhagic Stroke, and All-Cause Mortality in Retinal Vein Occlusion: A Nationwide Population-Based Cohort Study.

    abstract:Purpose:To investigate whether the risk of subsequent stroke, ischemic stroke, hemorrhagic stroke, and all-cause mortality is increased among retinal vein occlusion (RVO) patients compared to non-RVO patients. Methods:From the entire population of the Taiwan National Health Insurance Research Database (NHIRD) from 200...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2018/8629429

    authors: Chen YY,Yen YF,Lin JX,Feng SC,Wei LC,Lai YJ,Shen YC

    更新日期:2018-09-09 00:00:00

  • The Degeneration and Apoptosis Patterns of Cone Photoreceptors in rd11 Mice.

    abstract::The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration or apoptosis patterns of photoreceptors are still unclear in rd11 mi...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2017/9721362

    authors: Zhang H,Li X,Dai X,Han J,Zhang Y,Qi Y,He Y,Liu Y,Chang B,Pang JJ

    更新日期:2017-01-01 00:00:00

  • Effect of Active and Passive Smoking on Retinal Nerve Fibre Layer and Ganglion Cell Complex.

    abstract::Aim. To evaluate the possible structural and functional changes in the retinal nerve fibre layer (RNFL) and the ganglion cell complex (GCC) of chronic smokers and compare them with those of passive healthy smokers using spectral domain optical coherence tomography (SD-OCT) and pattern electroretinogram (PERG). Materia...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2017/6354025

    authors: El-Shazly AAE,Farweez YAT,Elewa LS,Elzankalony YA,Farweez BAT

    更新日期:2017-01-01 00:00:00

  • Systemic Factors Related to Intraocular Levels of Interleukin-6 and Vascular Endothelial Growth Factor in Diabetic Retinopathy.

    abstract::This study is for identifying systemic factors correlating with intraocular levels of interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF) in diabetic retinopathy. Forty-two consecutive patients undergoing pars plana vitrectomy (PPV) for PDR were included in this cross-sectional study. The aqueous humor ...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/4831967

    authors: Jung BJ,Lee MY,Jeon S

    更新日期:2019-07-17 00:00:00

  • Optic Neuritis in the Older Chinese Population: A 5-Year Follow-Up Study.

    abstract:Objective:This study aims to describe the clinical manifestations and outcomes in a cohort of older Chinese patients. Method:A retrospective study of patients aged ≥ 45 years who had a first episode of optic neuritis (ON) between May 2008 and November 2012. Clinical features at onset and last follow-up were analyzed w...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2017/3458356

    authors: Wang J,Zhou H,Qin L,Peng C,Zhao J,Teng D,Lin D,Ai N,Xu Q,Wei S

    更新日期:2017-01-01 00:00:00

  • Evaluation of cystoid macular edema using optical coherence tomography and fundus autofluorescence after uncomplicated phacoemulsification surgery.

    abstract::Aim. To investigate the utility of fundus autofluorescence (FAF) and optical coherence tomography (OCT) in the evaluation of cystoid macular edema (CME) following cataract surgery. Materials and Methods. Forty eyes of 29 patients undergone phacoemulsification, with posterior chamber intraocular lens implantation surge...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2013/376013

    authors: Sahin M,Cingü AK,Gözüm N

    更新日期:2013-01-01 00:00:00

  • Outer Retinal Layers' Thickness Changes in relation to Age and Choroidal Thickness in Normal Eyes.

    abstract:Purpose:To identify and correlate age-related changes in outer retinal layers' thickness and choroidal thickness (CT) in the normal eyes using spectral-domain optical coherence tomography (SD-OCT) and to investigate factors affecting these changes. Study Design:Observational cross-sectional study. Subjects and Method...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/1698967

    authors: Kamal Abdellatif M,Abdelmaguid Mohamed Elzankalony Y,Abdelmonsef Abdelhamid Ebeid A,Mohamed Ebeid W

    更新日期:2019-07-31 00:00:00

  • Measurement of the Orbital Soft Tissue Volume in Chinese Adults Based on Three-Dimensional CT Reconstruction.

    abstract::Quantitative measurement of the orbital soft tissue volume plays a very important role in the study of orbital diseases. The purpose of this study is to establish a computed tomography- (CT-) based three-dimensional (3D) reconstruction model and measure the orbital soft tissue volume in Chinese adults. We collected da...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/9721085

    authors: Du Y,Lu BY,Chen J,He JF

    更新日期:2019-07-02 00:00:00

  • Comparison of Solar Radiation and Myopia Occurrence in South Korean Children.

    abstract:Purpose:To investigate the association between regional solar radiation and myopia occurrence in South Korean children. Materials and Methods:A population-based cross-sectional study using data of 1218 children aged 7-9 years from the Korea National Health and Nutritional Examination Survey was conducted from January ...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/7643850

    authors: Choo HG,Rah SH,Kim SH

    更新日期:2019-06-10 00:00:00

  • Gradually Then Suddenly? Decline in Vision-Related Quality of Life as Glaucoma Worsens.

    abstract::Purpose. To evaluate the relationship between self-reported vision-related quality of life (VRQL) and visual field (VF) loss in people from glaucoma clinics. Methods. A postal survey using the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) was administered to people with a range of VF loss identifie...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2017/1621640

    authors: Jones L,Bryan SR,Crabb DP

    更新日期:2017-01-01 00:00:00

  • Smoking and age-related macular degeneration: review and update.

    abstract::Age-related macular degeneration (AMD) is one of the main socioeconomical health issues worldwide. AMD has a multifactorial etiology with a variety of risk factors. Smoking is the most important modifiable risk factor for AMD development and progression. The present review summarizes the epidemiological studies evalua...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1155/2013/895147

    authors: Velilla S,García-Medina JJ,García-Layana A,Dolz-Marco R,Pons-Vázquez S,Pinazo-Durán MD,Gómez-Ulla F,Arévalo JF,Díaz-Llopis M,Gallego-Pinazo R

    更新日期:2013-01-01 00:00:00

  • Group Analysis of Q Values Calculated with Tangential Radius of Curvature from Human Anterior Corneal Surface.

    abstract:Objective:To calculate the Q values from the human anterior corneal surface with the tangential radius of curvature and analyze its distribution characteristics in different age and refractive status groups. Methods:Tangential power maps of the anterior cornea from Orbscan II were acquired for 201 subjects' right eyes...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2018/7263564

    authors: Xia Z,Lin C,Huang X,Ying J,Shi M,Zheng S

    更新日期:2018-04-17 00:00:00

  • Evaluation of Subfoveal Choroidal Thickness in Internal Carotid Artery Stenosis.

    abstract::Purpose. To evaluate the relationship between internal carotid artery (ICA) stenosis and subfoveal choroidal thickness (SFCT) in the elderly population. Methods. A total of 42 eyes of 21 patients with more than 70% ICA stenosis (Group 1) on one side and less than 70% stenosis (Group 2) on the other side were recruited...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2016/5296048

    authors: Akçay Bİ,Kardeş E,Maçin S,Ünlü C,Özgürhan EB,Maçin A,Bozkurt TK,Ergin A,Surmeli R

    更新日期:2016-01-01 00:00:00

  • Comparison of Two Toric IOL Calculation Methods.

    abstract:Purpose:To compare two calculators for toric intraocular lens (IOL) calculation and to evaluate the prediction of refractive outcome. Methods:Sixty-four eyes of forty-five patients underwent cataract surgery followed by implantation of a toric intraocular lens (Zeiss Torbi 709 M) calculated by a standard industry calc...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2018/2840246

    authors: Kern C,Kortüm K,Müller M,Kampik A,Priglinger S,Mayer WJ

    更新日期:2018-01-10 00:00:00

  • Automated Detection of Macular Diseases by Optical Coherence Tomography and Artificial Intelligence Machine Learning of Optical Coherence Tomography Images.

    abstract:Purpose:Although optical coherence tomography (OCT) is essential for ophthalmologists, reading of findings requires expertise. The purpose of this study is to test deep learning with image augmentation for automated detection of chorioretinal diseases. Methods:A retina specialist diagnosed 1,200 OCT images. The diagno...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2019/6319581

    authors: Kuwayama S,Ayatsuka Y,Yanagisono D,Uta T,Usui H,Kato A,Takase N,Ogura Y,Yasukawa T

    更新日期:2019-04-09 00:00:00

  • Clinical Characteristics and Surgical Procedures for Children with Congenital Membranous Cataract.

    abstract:Objective:In a group case series, the clinical characteristics of congenital membranous cataract in children were studied to establish a system of classification and determine the surgical method suited for each type. Methods:Children (18 eyes) with congenital membranous cataract were examined by slit lamp, ultrasound...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2017/2370969

    authors: Long J,Xiang D,Guo Z,Chen L,Chen F,Wang J,Xie W,He S

    更新日期:2017-01-01 00:00:00

  • Comparison of two different scheimpflug devices in the detection of keratoconus, regular astigmatism, and healthy corneas.

    abstract::Aim. The aim of this study was to determine the intra- and interobserver variability of two Scheimpflug based camera systems, Pentacam and Sirius. In addition, the comparability of the measurements was tested in healthy subjects, subjects with regular astigmatism, and keratoconus patients. Methods. Intra- and interobs...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2015/315281

    authors: Finis D,Ralla B,Karbe M,Borrelli M,Schrader S,Geerling G

    更新日期:2015-01-01 00:00:00

  • Observation of Gonio Structures during Microhook Ab Interno Trabeculotomy Using a Novel Digital Microscope with Integrated Intraoperative Optical Coherence Tomography.

    abstract:Purpose:Observation of ocular structures using microscope-integrated intraoperative optical coherence tomography (iOCT) has been adopted. Using the novel digital ophthalmic microscope, ARTEVO 800 with iOCT, we tested the feasibility of trabecular meshwork (TM) imaging during microhook ab interno trabeculotomy, a minima...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2020/9024241

    authors: Ishida A,Sugihara K,Shirakami T,Tsutsui A,Manabe K,Tanito M

    更新日期:2020-07-17 00:00:00

  • A Meta-Analysis for Association of Maternal Smoking with Childhood Refractive Error and Amblyopia.

    abstract::Background. We aimed to evaluate the association between maternal smoking and the occurrence of childhood refractive error and amblyopia. Methods. Relevant articles were identified from PubMed and EMBASE up to May 2015. Combined odds ratio (OR) corresponding with its 95% confidence interval (CI) was calculated to eval...

    journal_title:Journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1155/2016/8263832

    authors: Li L,Qi Y,Shi W,Wang Y,Liu W,Hu M

    更新日期:2016-01-01 00:00:00