Abstract:
Purpose:The aim of this work was to describe the ultrastructure and behavior of peeled internal limiting membrane (ILM) in macular hole (MH) surgery. Methods:Seven patients with MH were included, and vitrectomy with ILM peeling was performed in all patients. The ILM inverted flap technique was used. Two other flaps of ILM of the same patient were collected and studied using light and transmission electron microscopy (TEM). ILM cell type, distribution, and morphology were analyzed, and the proliferation or fusion potential of the ILM interface was evaluated. Results:ILM vitreous sides in apposition showed signs of proliferative fibrotic activity, producing a basal membrane that merges ILM sides. Conclusions:Epiretinal cells in ILM show proliferative capacity, with formation of microfibrils between adjacent sides of the ILM, which may explain adherence of ILM flaps to the hole border, contributing to closure of the hole in MH surgery. This trail is registered with NCT03799575.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Faria MY,Sousa DC,Almeida BC,Pinto AL,Ferreira NPdoi
10.1155/2019/1345683subject
Has Abstractpub_date
2019-05-02 00:00:00pages
1345683eissn
2090-004Xissn
2090-0058journal_volume
2019pub_type
杂志文章abstract:Purpose:To evaluate a new technique of posterior capsulorhexis using air support to treat primary posterior capsular opacification (PCO) during cataract extraction surgery or to prevent postoperative PCO. Setting:(1) Ophthalmology department, Faculty of Medicine, Minia University, 61519, El-Minia, Egypt. (2) Security ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/3174709
更新日期:2019-12-21 00:00:00
abstract:Purpose:To analyze the results of three-year outcomes of combined epithelium-on cross-linking with femtosecond laser ICRS (cross-linking PLUS) for keratoconus management. Design:A retrospective multicenter clinical study. Methods:43 eyes of 38 patients were subjected to preoperative and postoperative UCVA, BCVA, refr...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/6907573
更新日期:2018-01-17 00:00:00
abstract::Background. The aim of this study is to investigate the ocular thermographic profiles in age-related macular degeneration (AMD) eyes and age-matched controls to detect possible hemodynamic abnormalities, which could be involved in the pathogenesis of the disease. Methods. 32 eyes with early AMD, 37 eyes with atrophic ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/281010
更新日期:2014-01-01 00:00:00
abstract::The functional visual acuity test which is the average of the visual acuities measured during a specific time frame (standard, 60 seconds) has been used recently to assess the visual function in various conditions. The availability of a shorter version of the functional visual acuity test promises to be patient friend...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/8950418
更新日期:2019-09-10 00:00:00
abstract::The aim of this study was to assess the oxidative stress status in eyes affected by synchysis scintillans and to compare it to vitreoretinal disorders without synchysis scintillans. Human aqueous and vitreous humors were obtained during vitrectomy from thirty-seven otherwise healthy patients that were randomly chosen ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/7231015
更新日期:2019-10-30 00:00:00
abstract::Purpose. To describe the SD-OCT findings in patients with diffuse unilateral subacute neuroretinitis (DUSN) and evaluate CRT and RNFL thickness. Methods. Patients with clinical diagnosis of DUSN who were submitted to SD-OCT were included in the study. Complete ophthalmologic examination and SD-OCT were performed. Cirr...
journal_title:Journal of ophthalmology
pub_type:
doi:10.1155/2011/285296
更新日期:2011-01-01 00:00:00
abstract::Macular pseudoholes (MPHs) and lamellar macular holes (LMHs) have been recently defined according to spectral domain optical coherence tomography (SD-OCT) criteria. A major feature for differentiating an MPH from an LMH remains the loss of foveal tissue. The anatomy of the foveola is peculiar with the macular pigment ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2019/4948212
更新日期:2019-02-10 00:00:00
abstract:Purpose:Glaucoma is the leading cause of irreversible blindness throughout the world. The pathogenesis of glaucoma is complex, and neuroprotection is a crucial aspect of therapy. High concentrations of extracellular glutamate are toxic to the optic nerve. The glutamate-aspartate transporter (GLAST) in retinal Müller ce...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/6128470
更新日期:2018-10-31 00:00:00
abstract:PURPOSE:To evaluate the static measurement of the accommodative stimulus-response curve with emoji symbols. METHODS:The accommodative stimulus-response curve was measured in 18 subjects using a Hartmann-Shack sensor to obtain the objective accommodative response from the Zernike defocus term. Measurements were acquire...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/4165706
更新日期:2017-01-01 00:00:00
abstract::Purpose. The aim of this study is to investigate the etiology and the clinical, microbiological, histopathological, and radiological findings of acquired dacryocystoceles. Methods. In this retrospective study, we reviewed the clinical records of 10 eyes of 8 patients with dacryocystoceles who underwent external dacryo...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/396782
更新日期:2014-01-01 00:00:00
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journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/2630704
更新日期:2019-08-29 00:00:00
abstract:Purpose:To investigate whether the risk of subsequent stroke, ischemic stroke, hemorrhagic stroke, and all-cause mortality is increased among retinal vein occlusion (RVO) patients compared to non-RVO patients. Methods:From the entire population of the Taiwan National Health Insurance Research Database (NHIRD) from 200...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/8629429
更新日期:2018-09-09 00:00:00
abstract::The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration or apoptosis patterns of photoreceptors are still unclear in rd11 mi...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/9721362
更新日期:2017-01-01 00:00:00
abstract::Aim. To evaluate the possible structural and functional changes in the retinal nerve fibre layer (RNFL) and the ganglion cell complex (GCC) of chronic smokers and compare them with those of passive healthy smokers using spectral domain optical coherence tomography (SD-OCT) and pattern electroretinogram (PERG). Materia...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/6354025
更新日期:2017-01-01 00:00:00
abstract::This study is for identifying systemic factors correlating with intraocular levels of interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF) in diabetic retinopathy. Forty-two consecutive patients undergoing pars plana vitrectomy (PPV) for PDR were included in this cross-sectional study. The aqueous humor ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/4831967
更新日期:2019-07-17 00:00:00
abstract:Objective:This study aims to describe the clinical manifestations and outcomes in a cohort of older Chinese patients. Method:A retrospective study of patients aged ≥ 45 years who had a first episode of optic neuritis (ON) between May 2008 and November 2012. Clinical features at onset and last follow-up were analyzed w...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/3458356
更新日期:2017-01-01 00:00:00
abstract::Aim. To investigate the utility of fundus autofluorescence (FAF) and optical coherence tomography (OCT) in the evaluation of cystoid macular edema (CME) following cataract surgery. Materials and Methods. Forty eyes of 29 patients undergone phacoemulsification, with posterior chamber intraocular lens implantation surge...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/376013
更新日期:2013-01-01 00:00:00
abstract:Purpose:To identify and correlate age-related changes in outer retinal layers' thickness and choroidal thickness (CT) in the normal eyes using spectral-domain optical coherence tomography (SD-OCT) and to investigate factors affecting these changes. Study Design:Observational cross-sectional study. Subjects and Method...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/1698967
更新日期:2019-07-31 00:00:00
abstract::Quantitative measurement of the orbital soft tissue volume plays a very important role in the study of orbital diseases. The purpose of this study is to establish a computed tomography- (CT-) based three-dimensional (3D) reconstruction model and measure the orbital soft tissue volume in Chinese adults. We collected da...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/9721085
更新日期:2019-07-02 00:00:00
abstract:Purpose:To investigate the association between regional solar radiation and myopia occurrence in South Korean children. Materials and Methods:A population-based cross-sectional study using data of 1218 children aged 7-9 years from the Korea National Health and Nutritional Examination Survey was conducted from January ...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/7643850
更新日期:2019-06-10 00:00:00
abstract::Purpose. To evaluate the relationship between self-reported vision-related quality of life (VRQL) and visual field (VF) loss in people from glaucoma clinics. Methods. A postal survey using the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) was administered to people with a range of VF loss identifie...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/1621640
更新日期:2017-01-01 00:00:00
abstract::Age-related macular degeneration (AMD) is one of the main socioeconomical health issues worldwide. AMD has a multifactorial etiology with a variety of risk factors. Smoking is the most important modifiable risk factor for AMD development and progression. The present review summarizes the epidemiological studies evalua...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2013/895147
更新日期:2013-01-01 00:00:00
abstract:Objective:To calculate the Q values from the human anterior corneal surface with the tangential radius of curvature and analyze its distribution characteristics in different age and refractive status groups. Methods:Tangential power maps of the anterior cornea from Orbscan II were acquired for 201 subjects' right eyes...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/7263564
更新日期:2018-04-17 00:00:00
abstract::Purpose. To evaluate the relationship between internal carotid artery (ICA) stenosis and subfoveal choroidal thickness (SFCT) in the elderly population. Methods. A total of 42 eyes of 21 patients with more than 70% ICA stenosis (Group 1) on one side and less than 70% stenosis (Group 2) on the other side were recruited...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/5296048
更新日期:2016-01-01 00:00:00
abstract:Purpose:To compare two calculators for toric intraocular lens (IOL) calculation and to evaluate the prediction of refractive outcome. Methods:Sixty-four eyes of forty-five patients underwent cataract surgery followed by implantation of a toric intraocular lens (Zeiss Torbi 709 M) calculated by a standard industry calc...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/2840246
更新日期:2018-01-10 00:00:00
abstract:Purpose:Although optical coherence tomography (OCT) is essential for ophthalmologists, reading of findings requires expertise. The purpose of this study is to test deep learning with image augmentation for automated detection of chorioretinal diseases. Methods:A retina specialist diagnosed 1,200 OCT images. The diagno...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/6319581
更新日期:2019-04-09 00:00:00
abstract:Objective:In a group case series, the clinical characteristics of congenital membranous cataract in children were studied to establish a system of classification and determine the surgical method suited for each type. Methods:Children (18 eyes) with congenital membranous cataract were examined by slit lamp, ultrasound...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/2370969
更新日期:2017-01-01 00:00:00
abstract::Aim. The aim of this study was to determine the intra- and interobserver variability of two Scheimpflug based camera systems, Pentacam and Sirius. In addition, the comparability of the measurements was tested in healthy subjects, subjects with regular astigmatism, and keratoconus patients. Methods. Intra- and interobs...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/315281
更新日期:2015-01-01 00:00:00
abstract:Purpose:Observation of ocular structures using microscope-integrated intraoperative optical coherence tomography (iOCT) has been adopted. Using the novel digital ophthalmic microscope, ARTEVO 800 with iOCT, we tested the feasibility of trabecular meshwork (TM) imaging during microhook ab interno trabeculotomy, a minima...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/9024241
更新日期:2020-07-17 00:00:00
abstract::Background. We aimed to evaluate the association between maternal smoking and the occurrence of childhood refractive error and amblyopia. Methods. Relevant articles were identified from PubMed and EMBASE up to May 2015. Combined odds ratio (OR) corresponding with its 95% confidence interval (CI) was calculated to eval...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/8263832
更新日期:2016-01-01 00:00:00