Exosomes derived from human umbilical cord mesenchymal stem cells protect against cisplatin-induced ovarian granulosa cell stress and apoptosis in vitro.

abstract：:In this work, Ni nanoparticles were directly decorated on graphene (G) nanosheets via mechanical ball milling. Based on transmission electron microscopy observations, the Ni nanoparticles were well dispersed and attached to the G nanosheet without any agglomerations. Electrochemical results showed that the capacitance...

journal_title：Scientific reports

authors： Mohd Zaid NA,Idris NH

更新日期：2016-08-24 00:00:00

abstract：:Myocyte Enhancer Factor 2 (MEF2) mediates cardiac remodelling in heart failure (HF) and is also a target of β-adrenergic signalling, a front-line treatment for HF. We identified global gene transcription networks involved in HF with and without β-blocker treatment. Experimental HF by transverse aortic constriction (TA...

journal_title：Scientific reports

authors： Tobin SW,Hashemi S,Dadson K,Turdi S,Ebrahimian K,Zhao J,Sweeney G,Grigull J,McDermott JC

更新日期：2017-06-30 00:00:00

abstract：:The basic leucine zipper (bZIP) is a widely known transcription factors family in eukaryotes. In plants, the role of bZIP proteins are crucial in various biological functions such as plant growth and development, seed maturation, response to light signal and environmental stress. To date, bZIP protein family has been ...

journal_title：Scientific reports

authors： Li H,Li L,ShangGuan G,Jia C,Deng S,Noman M,Liu Y,Guo Y,Han L,Zhang X,Dong Y,Ahmad N,Du L,Li H,Yang J

更新日期：2020-09-23 00:00:00

abstract：:Graphene grown by high temperature molecular beam epitaxy on hexagonal boron nitride (hBN) forms continuous domains with dimensions of order 20 μm, and exhibits moiré patterns with large periodicities, up to ~30 nm, indicating that the layers are highly strained. Topological defects in the moiré patterns are observed ...

journal_title：Scientific reports

authors： Summerfield A,Davies A,Cheng TS,Korolkov VV,Cho Y,Mellor CJ,Foxon CT,Khlobystov AN,Watanabe K,Taniguchi T,Eaves L,Novikov SV,Beton PH

更新日期：2016-03-01 00:00:00

abstract：:The epithelial-mesenchymal plasticity, in tight association with stemness, contributes to the mammary gland homeostasis, evolution of early neoplastic lesions and cancer dissemination. Focused on cell surfaceome, we used mouse models of pre-neoplastic mammary epithelial and cancer stem cells to reveal the connection b...

journal_title：Scientific reports

authors： Remšík J,Pícková M,Vacek O,Fedr R,Binó L,Hampl A,Souček K

更新日期：2020-07-09 00:00:00

abstract：:Coastal zones constitute one of the most heavily populated and developed land zones in the world. Despite the utility and economic benefits that coasts provide, there is no reliable global-scale assessment of historical shoreline change trends. Here, via the use of freely available optical satellite images captured si...

journal_title：Scientific reports

authors： Luijendijk A,Hagenaars G,Ranasinghe R,Baart F,Donchyts G,Aarninkhof S

更新日期：2018-04-27 00:00:00

abstract：:The aim of this systematic review was taken to investigate the efficacy and safety of docetaxel plus thalidomide vs. docetaxel alone for treating androgen-independent prostate cancer (AIPC). Data were collected from different databases independently by three researchers according to the pre-defined inclusion and exclu...

journal_title：Scientific reports

authors： Chen L,Qiu X,Wang R,Xie X

更新日期：2014-04-28 00:00:00

abstract：:A systematic chemomechanical network model for the molecular motor kinesin is presented in this report. The network model is based on the nucleotide-dependent binding affinity of the heads to an microtubule (MT) and the asymmetries and similarities between the chemical transitions caused by the intramolecular strain b...

journal_title：Scientific reports

authors： Sumi T

更新日期：2017-04-25 00:00:00

abstract：:Current image processing methods for dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) do not capture complex dynamic information of time-signal intensity curves. We investigated whether an autoencoder-based pattern analysis of DSC MRI captured representative temporal features that improves tissue...

journal_title：Scientific reports

authors： Park JE,Kim HS,Lee J,Cheong EN,Shin I,Ahn SS,Shim WH

更新日期：2020-12-08 00:00:00

abstract：:Regional abnormalities in brain structure and function, as well as disrupted connectivity, have been found repeatedly in adolescents with conduct disorder (CD). Yet, the large-scale brain topology associated with CD is not well characterized, and little is known about the systematic neural mechanisms of CD. We employe...

journal_title：Scientific reports

authors： Jiang Y,Liu W,Ming Q,Gao Y,Ma R,Zhang X,Situ W,Wang X,Yao S,Huang B

更新日期：2016-11-14 00:00:00

abstract：:Male Wistar rats were exposed to herbicide, pendimethalin (PND) at varying oral doses of 62.5, 125 and 250 mg/kg b.w. for 14 days. Toxiological effects were assessed in terms of oxidative stress, DNA damage, histopathological alterations and induction of anti-inflammatory and apoptotic responses linked Bax, Bcl-2, IFN...

journal_title：Scientific reports

authors： Ahmad MI,Zafeer MF,Javed M,Ahmad M

更新日期：2018-11-20 00:00:00

abstract：:Recent studies indicate that urinary mitochondrial DNA (mtDNA) is predictive of ischemic AKI and is related to delayed graft function (DGF) in renal transplantation. Nevertheless, the clinical implications and prognostic value of urinary mtDNA in kidney transplantation remain undetermined. Here, we aimed to evaluate t...

journal_title：Scientific reports

authors： Kim K,Moon H,Lee YH,Seo JW,Kim YG,Moon JY,Kim JS,Jeong KH,Lee TW,Ihm CG,Lee SH

更新日期：2019-12-09 00:00:00

abstract：:Giant spin Hall effect (GSHE) has received significant attention for its potential in future spintronic applications. Spin current via GSHE-based thin films provides an effective and promising means to manipulate magnetization. However, an external in-plane magnetic field is required to consistently switch the perpend...

journal_title：Scientific reports

authors： Chen W,Qian L,Xiao G

更新日期：2018-05-25 00:00:00

abstract：:Connectivity is fundamentally important for shaping the resilience of complex human and natural networks when systems are disturbed. Ecosystem resilience is, in part, shaped by the spatial arrangement of habitats, the permeability and fluxes between them, the stabilising functions performed by organisms, their dispers...

journal_title：Scientific reports

authors： Pearson RM,Schlacher TA,Jinks KI,Olds AD,Brown CJ,Connolly RM

更新日期：2021-01-13 00:00:00

abstract：:For augmentation or reconstruction of urinary bladder after cystectomy, bladder urothelium derived from human induced pluripotent stem cells (hiPSCs) has recently received focus. However, previous studies have only shown the emergence of cells expressing some urothelial markers among derivatives of hiPSCs, and no repo...

journal_title：Scientific reports

authors： Suzuki K,Koyanagi-Aoi M,Uehara K,Hinata N,Fujisawa M,Aoi T

更新日期：2019-07-19 00:00:00

abstract：:A novel design of thin-film crystalline silicon solar cell (TF C-Si-SC) is proposed and numerically analyzed. The reported SC has 1.0 µm thickness of C-Si with embedded dielectric silicon dioxide nanowires (NWs). The introduced NWs increase the light scattering in the active layer which improves the optical path lengt...

journal_title：Scientific reports

authors： Elrabiaey MA,Hussein M,Hameed MFO,Obayya SSA

更新日期：2020-10-16 00:00:00

abstract：:Vitamin D and parathyroid hormone (PTH) regulate mineral metabolism and are required to maintain calcium levels. Vitamin D deficiency is common, particularly during pregnancy, and has been associated with hypertensive disorders of pregnancy. We sought to determine whether maternal 25(OH)D, PTH and calcium concentratio...

journal_title：Scientific reports

authors： Santorelli G,Whitelaw D,Farrar D,West J,Lawlor DA

更新日期：2019-02-04 00:00:00

abstract：:The ability of human embryonic stem cells (hESCs) to differentiate into skeletal muscle cells is an important criterion in using them as a cell source to ameliorate skeletal muscle impairments. However, differentiation of hESCs into skeletal muscle cells still remains a challenge, often requiring introduction of trans...

journal_title：Scientific reports

authors： Hwang Y,Suk S,Shih YR,Seo T,Du B,Xie Y,Li Z,Varghese S

更新日期：2014-08-01 00:00:00

abstract：:Gelatin-methacryloyl (GelMA) is one of the most commonly used photopolymerizable biomaterials in bio-applications. However, GelMA synthesis remains suboptimal, as its reaction parameters have not been fully investigated. The goal of this study is to establish an optimal route for effective and controllable GelMA synth...

journal_title：Scientific reports

authors： Shirahama H,Lee BH,Tan LP,Cho NJ

更新日期：2016-08-09 00:00:00

abstract：:The common variants in lysyl oxidase-like 1 gene (LOXL1) are associated with exfoliation glaucoma (XFG) patients developed through exfoliation syndrome (XFS). However, the risk allele of a variant in LOXL1 has been found to be inverted between Asian and Caucasian populations. Therefore, we newly performed a genome-wid...

journal_title：Scientific reports

authors： Nakano M,Ikeda Y,Tokuda Y,Fuwa M,Ueno M,Imai K,Sato R,Omi N,Adachi H,Kageyama M,Mori K,Kinoshita S,Tashiro K

更新日期：2014-06-18 00:00:00

abstract：:We compared the effects of 12-week programs of resistance training (RT), high-intensity interval aerobic training (HIAT), and moderate-intensity continuous aerobic training (MICT). The primary goal was to evaluate the therapeutic effects of the exercise modalities for the management of nonalcoholic fatty liver disease...

journal_title：Scientific reports

authors： Oh S,So R,Shida T,Matsuo T,Kim B,Akiyama K,Isobe T,Okamoto Y,Tanaka K,Shoda J

更新日期：2017-02-22 00:00:00

abstract：:Toward the increasing demands of portable energy storage and electric vehicle applications, the widely used graphite anodes with significant drawbacks become more and more unsuitable. Herein, we report a novel scaffold of hierarchical silicon nanowires-carbon textiles anodes fabricated via a facile method. Further, co...

journal_title：Scientific reports

authors： Liu B,Wang X,Chen H,Wang Z,Chen D,Cheng YB,Zhou C,Shen G

更新日期：2013-01-01 00:00:00

abstract：:Enhanced and immediate expression of cyclooxygenase-2 (COX-2) mRNA is observed in IL-1β-stimulated OA chondrocytes but the synthesis of protein found significantly delayed. Here we investigated the role of stress granules (SGs), ribonucleoprotein complexes that regulate mRNA translation, in the delayed translation of ...

journal_title：Scientific reports

authors： Ansari MY,Haqqi TM

更新日期：2016-06-08 00:00:00

abstract：:Photoreceptor function is impaired in many retinal diseases like age-related macular degeneration. Currently, assessment of the photoreceptor function for the early diagnosis and monitoring of these diseases is either subjective, as in visual field testing, requires contact with the eye, like in electroretinography, o...

journal_title：Scientific reports

authors： Messner A,Werkmeister RM,Seidel G,Stegmann H,Schmetterer L,Aranha Dos Santos V

更新日期：2019-09-20 00:00:00

abstract：:Hypoxia-inducible transcription factors (HIF) form heterodimeric complexes that mediate cell responses to hypoxia. The oxygen-dependent stability and activity of the HIF-α subunits is traditionally associated to post-translational modifications such as hydroxylation, acetylation, ubiquitination, and phosphorylation. H...

journal_title：Scientific reports

authors： Fala AM,Oliveira JF,Adamoski D,Aricetti JA,Dias MM,Dias MVB,Sforça ML,Lopes-de-Oliveira PS,Rocco SA,Caldana C,Dias SMG,Ambrosio ALB

更新日期：2015-08-03 00:00:00

abstract：:Part of the symptomatology of post-traumatic stress disorder (PTSD) are alterations in arousal and reactivity which could be related to a maladaptive increase in the automated sensory change detection system of the brain. In the current EEG study we investigated whether the brain's response to a simple auditory sensor...

journal_title：Scientific reports

authors： Bangel KA,van Buschbach S,Smit DJA,Mazaheri A,Olff M

更新日期：2017-11-29 00:00:00

abstract：:We demonstrate a label-free imaging approach to study cardiac remodeling of fibrotic and hypertrophic hearts, bridging scales from the whole organ down to the molecular level. To this end, we have used mice subjected to transverse aortic constriction and imaged adjacent cardiac tissue sections by microfocus X-ray diff...

journal_title：Scientific reports

authors： Nicolas JD,Khan A,Markus A,Mohamed BA,Toischer K,Alves F,Salditt T

更新日期：2020-11-09 00:00:00

abstract：:Childhood and adolescent overweight and obesity are increasing in China, but limited information is available on its secular trends in Guangzhou. In this cross-sectional study, ten-wave successive data were obtained from the physical fitness surveillance for students in Guangzhou from 2003 to 2012. A total of 2,619,15...

journal_title：Scientific reports

authors： Zong Y,Xie R,Deng N,Liu L,Tan W,Gao Y,Yang J,Yang Y

更新日期：2017-09-21 00:00:00

abstract：:Rodents are important reservoir hosts of many important zoonotic viruses. The family Picornaviridae contains clinically important pathogens that infect humans and animals, and increasing numbers of rodent picornaviruses have recently been associated with zoonoses. We collected 574 pharyngeal and anal swab specimens fr...

journal_title：Scientific reports

authors： Du J,Lu L,Liu F,Su H,Dong J,Sun L,Zhu Y,Ren X,Yang F,Guo F,Liu Q,Wu Z,Jin Q

更新日期：2016-09-29 00:00:00

abstract：:Ferritin has gained significant attention as a potential reporter gene for in vivo imaging by magnetic resonance imaging (MRI). However, due to the ferritin ferrihydrite core, the relaxivity and sensitivity for detection of native ferritin is relatively low. We report here on a novel chimeric magneto-ferritin reporter...

journal_title：Scientific reports

authors： Radoul M,Lewin L,Cohen B,Oren R,Popov S,Davidov G,Vandsburger MH,Harmelin A,Bitton R,Greneche JM,Neeman M,Zarivach R

更新日期：2016-05-23 00:00:00