Pendimethalin-induced oxidative stress, DNA damage and activation of anti-inflammatory and apoptotic markers in male rats.

abstract：:Prolonged intake of excessive amounts of ethanol is known to have adverse effects on the central nervous system (CNS). Here we investigated the effects of acute and chronic ethanol exposure and withdrawal from chronic ethanol exposure on glymphatic function, which is a brain-wide metabolite clearance system connected ...

journal_title：Scientific reports

authors： Lundgaard I,Wang W,Eberhardt A,Vinitsky HS,Reeves BC,Peng S,Lou N,Hussain R,Nedergaard M

更新日期：2018-02-02 00:00:00

abstract：:Circular RNAs (circRNAs) are abundantly expressed in the haematopoietic compartment, but knowledge on their diversity among blood cell types is still limited. Nevertheless, emerging data indicate an array of circRNA functions exerted through interactions with other RNAs and proteins, by translation into peptides, and ...

journal_title：Scientific reports

authors： Gaffo E,Boldrin E,Dal Molin A,Bresolin S,Bonizzato A,Trentin L,Frasson C,Debatin KM,Meyer LH,Te Kronnie G,Bortoluzzi S

更新日期：2019-10-11 00:00:00

abstract：:The abundance and sinking of particulate black carbon (PBC) were examined for the first time in the western Arctic and Subarctic Oceans. In the central Arctic Ocean, high PBC concentrations with a mean of 0.021 ± 0.016 μmol L(-1) were observed in the marginal ice zone (MIZ). A number of parameters, including temperatu...

journal_title：Scientific reports

authors： Fang Z,Yang W,Chen M,Zheng M,Hu W

更新日期：2016-07-15 00:00:00

abstract：:Area under a receiver-operating-characteristic (AUROC) curve is widely used in medicine to summarize the ability of a continuous predictive marker to predict a binary outcome. This study illustrated how a U-shaped or inverted U-shaped continuous predictor would affect the shape and magnitude of its AUROC curve in pred...

journal_title：Scientific reports

authors： Ho KM

更新日期：2017-08-31 00:00:00

abstract：:Histamine is an important neurotransmitter that contributes to various processes, including the sleep-wake cycle, learning, memory, and stress responses. Its actions are mediated through histamine H1-H4 receptors. Gene knockout and pharmacological studies have revealed the importance of H1 receptors in learning and me...

journal_title：Scientific reports

authors： Kárpáti A,Yoshikawa T,Naganuma F,Matsuzawa T,Kitano H,Yamada Y,Yokoyama M,Futatsugi A,Mikoshiba K,Yanai K

更新日期：2019-11-11 00:00:00

abstract：:On an SiO2-patterned c-plane sapphire substrate, GaN domains were grown with their polarity controlled in accordance with the pattern. While N-polar GaN was grown on hexagonally arranged circular openings, Ga-polar GaN was laterally overgrown on mask regions due to polarity inversion occurring at the boundary of the c...

journal_title：Scientific reports

authors： Jang D,Jue M,Kim D,Kim HS,Lee H,Kim C

更新日期：2018-03-07 00:00:00

abstract：:An efficient [4 + 1] annulation between α-bromooximes and sulfur ylides via in situ generation of nitrosoalkenes under mild basic reaction conditions has been developed, providing an expeditious and scalable approach to synthesize biologically interesting isoxazoline derivatives with good to excellent yields. ...

journal_title：Scientific reports

authors： Hua TB,Liu CX,Hu WM,Wang L,Yang QQ

更新日期：2021-01-22 00:00:00

abstract：:Health-risk assessments of temperature are central to determine total non-accidental human mortality; however, few studies have investigated the effect of temperature on accidental human mortality. We performed a time-series study combined with a distributed lag non-linear model (DLNM) to quantify the non-linear and d...

journal_title：Scientific reports

authors： Lian T,Fu Y,Sun M,Yin M,Zhang Y,Huang L,Huang J,Xu Z,Mao C,Ni J,Liu G

更新日期：2020-05-21 00:00:00

abstract：:Geriatric trauma is a major socio-economic problem, especially among the aging Japanese society. Geriatric people are more vulnerable to trauma than younger people; thus, their outcomes are often severe. This study evaluates the characteristics of geriatric trauma divided by age in the Japanese population. We evaluate...

journal_title：Scientific reports

authors： Miyoshi Y,Kondo Y,Hirano Y,Ishihara T,Sueyoshi K,Okamoto K,Tanaka H

更新日期：2020-11-05 00:00:00

abstract：:Whole-room indirect calorimeters (WRICs) have traditionally been used for real-time resting metabolic rate (RMR) measurements, while metabolic rate (MR) during short-interval exercises has commonly been measured by metabolic carts (MCs). This study aims to investigate the feasibility of incorporating short-interval ex...

journal_title：Scientific reports

authors： Chen S,Scott C,Pearce JV,Farrar JS,Evans RK,Celi FS

更新日期：2020-08-31 00:00:00

abstract：:Betaine alleviates high-fat diet-induced fatty liver and prenatal betaine programs offspring hepatic lipid metabolism. Excessive corticosterone (CORT) exposure causes fatty liver in chickens, yet it remains unknown whether and how prenatal betaine modulates the susceptibility of CORT-induced fatty liver later in life....

journal_title：Scientific reports

authors： Hu Y,Sun Q,Liu J,Jia Y,Cai D,Idriss AA,Omer NA,Zhao R

更新日期：2017-01-06 00:00:00

abstract：:Organic carbon (OC) stability in tropical soils is strongly interlinked with multivalent cation interaction and mineral association. Low molecular weight organic acids (LMWOAs) represent the readily biodegradable OC. Therefore, investigating retention mechanisms of LMWOAs in mineral-cation-LMWOAs systems is critical t...

journal_title：Scientific reports

authors： Yang J,Wang J,Pan W,Regier T,Hu Y,Rumpel C,Bolan N,Sparks D

更新日期：2016-05-23 00:00:00

abstract：:Kaposiform hemangioendothelioma (KHE) is a relatively rare vascular tumor with an aggressive and infiltrating nature. Previous studies have revealed an exclusive relationship between KHE and Kasabach-Merritt Phenomenon (KMP), which is associated with high morbidity and mortality. No universally accepted treatment moda...

journal_title：Scientific reports

authors： Wu HW,Wang X,Zhang L,Zhao HG,Wang YA,Su LX,Fan XD,Zheng JW

更新日期：2016-10-31 00:00:00

abstract：:Histone deacetylase inhibition (HDACi) has been suggested as a promising approach to bolster TLR-mediated induction of antimicrobial peptides such as human β-defensin 2 (hBD2). In inflammatory bowel disease (IBD), Crohn's disease (CD) patients display an attenuated expression of hBD2 as compared to ulcerative colitis ...

journal_title：Scientific reports

authors： Stebe-Frick S,Ostaff MJ,Stange EF,Malek NP,Wehkamp J

更新日期：2018-08-27 00:00:00

abstract：:Stem cell therapy that can restore function to damaged tissue, avoid host rejection and reduce inflammation throughout body without use of immunosuppressive drugs. The established methods were used to identify and to isolate specific stem cell markers by FACS or by immunomagnetic cell separation. The procedures for di...

journal_title：Scientific reports

authors： Kim MS,Lee MH,Kwon BJ,Kim D,Koo MA,Seon GM,Park JC

更新日期：2017-08-29 00:00:00

abstract：:Transient permeabilisation of the cell membrane is a critical step to introduce drugs or DNA into living cells, yet challenging for both biological research and therapeutic applications. To achieve this, electroporation (or electropermeabilisation) has become a widely used method due to its simplicity to deliver almos...

journal_title：Scientific reports

authors： Perrier DL,Rems L,Kreutzer MT,Boukany PE

更新日期：2018-03-19 00:00:00

abstract：:The effects of climate change on the taste and textural attributes of foods remain largely unknown, despite much public interest. On the basis of 30-40 years of records, we provide evidence that the taste and textural attributes of apples have changed as a result of recent global warming. Decreases in both acid concen...

journal_title：Scientific reports

authors： Sugiura T,Ogawa H,Fukuda N,Moriguchi T

更新日期：2013-01-01 00:00:00

abstract：:Although thimerosal, an ethylmercury-based preservative, has been removed from most pediatric vaccines in the United States, some multidose vaccines, such as influenza vaccines, still contain thimerosal. Considering that a growing number of studies indicate involvement of the gut microbiome in infant immune developmen...

journal_title：Scientific reports

authors： Hasegawa Y,Curtis B,Yutuc V,Rulien M,Morrisroe K,Watkins K,Ferrier C,English C,Hewitson L,Slupsky CM

更新日期：2018-10-26 00:00:00

abstract：:Hand, foot, and mouth disease (HFMD), predominantly occurs among infants and children. Previous studies have shown that suitable, stable temperatures favor HFMD virus reproduction; however, temperature fluctuations also affect virus transmission, and there are, so far, no studies concerning the association between suc...

journal_title：Scientific reports

authors： Xu C,Zhang X,Wang L,Zhou Y,Xiao G,Liao J

更新日期：2020-02-13 00:00:00

abstract：:Wave propagation is an important characteristic for pattern formation and pattern dynamics. To date, various waves in homogeneous media have been investigated extensively and have been understood to a great extent. However, the wave behaviors in heterogeneous media have been studied and understood much less. In this w...

journal_title：Scientific reports

authors： Cui X,Huang X,Hu G

更新日期：2016-05-04 00:00:00

abstract：:The peripheral sensory system is critical to regulating motor plasticity and motor recovery. Peripheral electrical stimulation (ES) can generate constant and adequate sensory input to influence the excitability of the motor cortex. The aim of this proof of concept study was to assess whether ES prior to each hand func...

journal_title：Scientific reports

authors： Pan LH,Yang WW,Kao CL,Tsai MW,Wei SH,Fregni F,Chen VC,Chou LW

更新日期：2018-06-15 00:00:00

abstract：:Molecular level understanding of permeation of nanoparticles through human skin establishes the basis for development of novel transdermal drug delivery systems and design and formulation of cosmetics. Recent experiments suggest that surface coated nano-sized gold nanoparticles (AuNPs) can penetrate the rat and human ...

journal_title：Scientific reports

authors： Gupta R,Rai B

更新日期：2017-03-28 00:00:00

abstract：:Sorption and desorption determine the amount of an herbicide in soil solution. Therefore, knowledge of the sorption and desorption coefficients in different soils is an essential factor to estimate the potential for environmental contamination by herbicides. We evaluated the feasibility of multivariate and linear disc...

journal_title：Scientific reports

authors： Chagas PSFD,Souza MF,Dombroski JLD,Junior RSO,Nunes GHS,Pereira GAM,Silva TS,Passos ABRJ,Santos JBD,Silva DV

更新日期：2019-05-27 00:00:00

abstract：:Hollow silica spheres (HSS) with special interior spaces, high specific surface area and excellent adsorption and permeability performance were synthesized via micelle-template method using cetyl trimethyl ammonium bromide (CTAB) micelles as soft template and tetraethoxysilane (TEOS) as silica precursor. SEM, TEM, FT-...

journal_title：Scientific reports

authors： Bao Y,Wang T,Kang Q,Shi C,Ma J

更新日期：2017-04-21 00:00:00

abstract：:While cerebrospinal fluid (CSF) biomarkers for Creutzfeldt-Jakob disease (CJD) are established and partly included in the diagnostic criteria, no blood biomarkers are available. Here, we assessed the utility of serum neurofilament light chain (NF-L) and tau protein in comparison to CSF markers (NF-L and phosphorylated...

journal_title：Scientific reports

authors： Steinacker P,Blennow K,Halbgebauer S,Shi S,Ruf V,Oeckl P,Giese A,Kuhle J,Slivarichova D,Zetterberg H,Otto M

更新日期：2016-12-08 00:00:00

abstract：:Antidepressants have been the object of an international controversy for about thirty years. Some patients are inclined to develop suicidal ideation (SI) at antidepressant onset; this phenomenon is known as Treatment Emergent Suicidal Ideation (TESI), and it has conducted regulatory bodies to prompt warnings on antide...

journal_title：Scientific reports

authors： Nobile B,Ramoz N,Jaussent I,Gorwood P,Olié E,Castroman JL,Guillaume S,Courtet P

更新日期：2019-02-22 00:00:00

abstract：:The future Internet is very likely the mixture of all-optical Internet with low power consumption and quantum Internet with absolute security guaranteed by the laws of quantum mechanics. Photons would be used for processing, routing and com-munication of data, and photonic transistor using a weak light to control a st...

journal_title：Scientific reports

authors： Hu CY

更新日期：2017-03-28 00:00:00

abstract：:Rhythms of life are dictated by oscillations, which take place in a wide rage of biological scales. In bacteria, for example, oscillations have been proven to control many fundamental processes, ranging from gene expression to cell divisions. In genetic circuits, oscillations originate from elemental block such as aut...

journal_title：Scientific reports

authors： Ruocco G,Fratalocchi A

更新日期：2014-11-18 00:00:00

abstract：:TLR4 is implicated in diseases associated with chronic low-grade inflammation, yet homeostatic signaling mechanisms that prevent and/or are affected by chronic TLR4 activation are largely uncharacterized. We recently reported that LPS/TLR4 activates in human leukocytes signaling intermediates (SI), abbreviated TLR4-SI...

journal_title：Scientific reports

authors： Zhang Z,Amorosa LF,Petrova A,Coyle S,Macor M,Nair M,Lee LY,Haimovich B

更新日期：2019-05-07 00:00:00

abstract：:Chronic stress and prolonged activation of defence pathways have deleterious consequences for the cell. Dietary restriction is believed to be beneficial as it induces the cellular stress response machinery. We report here that although the phenomenon is beneficial in a wild-type cell, dietary restriction leads to an i...

journal_title：Scientific reports

authors： Bhadra AK,Das E,Roy I

更新日期：2016-09-16 00:00:00