Abstract：
:Stem cell therapy that can restore function to damaged tissue, avoid host rejection and reduce inflammation throughout body without use of immunosuppressive drugs. The established methods were used to identify and to isolate specific stem cell markers by FACS or by immunomagnetic cell separation. The procedures for distinguishing population of stem cells took a time and needed many preparations. Here we suggest an electrotaxis analysis as a new method to evaluate the homogeneity of mesenchymal stem cells which can observe the stem cell population in culture condition and wide use to various types of stem cells. Human mesenchymal stem cell, adipose derived stem cell, tonsil derived stem cell and osteogenic differentiated cells migrated toward anode but the migration speed of differentiated cells was significantly decreased versus that of stem cells. In mixture of stem cells and differentiated cells condition, we identified that the ratio of stem cell versus differentiated cell was matched with the homogeneity evaluation data of stem cells based on electrotaxis analysis. As a result, our evaluation tool has the possibility of the wide use to stem cell homogeneity evaluation and might be used as the stem cell quality control during stem cell culture without any additional antibodies.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Kim MS,Lee MH,Kwon BJ,Kim D,Koo MA,Seon GM,Park JCdoi
10.1038/s41598-017-09543-0subject
Has Abstractpub_date
2017-08-29 00:00:00pages
9582issue
1issn
2045-2322pii
10.1038/s41598-017-09543-0journal_volume
7pub_type
杂志文章abstract：:The human cervical cancer oncogene (HCCR) has been found to be overexpressed in a variety of human cancers. However, the level of expression of HCCR and its biological function in gastric cancer are largely unknown. In this study, we evaluated HCCR expression in several gastric cancer cell lines and in one normal gast...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24196
更新日期：2016-04-07 00:00:00
abstract：:The 8th edition of TNM staging system has been released and it incorporates many changes to the T and N classifications for pancreatic cancer. Comparative study between the 7th and 8th edition of TNM staging system from Asian population has not been reported yet. This study aimed to compare the 7th and 8th edition of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28193-4
更新日期：2018-07-10 00:00:00
abstract：:A body with mechanical sensors may remotely detect particles suspended in the surrounding fluid via controlled agitation. Here we propose a sensory mode that relies on generating unsteady flow and sensing particle-induced distortions in the flow field. We demonstrate the basic physical principle in a simple analytical...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58880-0
更新日期：2020-02-14 00:00:00
abstract：:The enzyme browning reaction results in grey speckles on tobacco leaves, which impairs the value and industrial usability of tobacco leaves. To demonstrate the influences of different browning degrees (BDs) of tobacco leaves on the usability of different cultivars and positions and identified structure of brown (grey)...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-54360-2
更新日期：2019-11-28 00:00:00
abstract：:Successful adaptation to passive hyperthermia requires continual adjustment of circulation, which is mediated mainly by the autonomic nervous system. The goal of this study was to explore the alterations in spontaneous cardiovagal baroreflex sensitivity (BRS) during exposure to a hot environment. To continuously follo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39172-8
更新日期：2019-02-22 00:00:00
abstract：:Although the growth of graphene by chemical vapor deposition is a production technique that guarantees high crystallinity and superior electronic properties on large areas, it is still a challenge for manufacturers to efficiently scale up the production to the industrial scale. In this context, issues related to the p...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09811-z
更新日期：2017-08-30 00:00:00
abstract：:Neuronal activity-dependent synaptic plasticity, a basis for learning and memory, is tightly correlated with the pattern of increase in intracellular Ca(2+) concentration ([Ca(2+)](i)). Here, using combined application of electrophysiological experiments and systems biological simulation, we show that such a correlati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00143
更新日期：2011-01-01 00:00:00
abstract：:The bronchoscopy, though usually safe, is occasionally associated with complications, such as pneumonia. However, the use of prophylactic antibiotics is not recommended by the guidelines of the British Thoracic Society. Thus far there are few reports of the risk factors for post-bronchoscopy pneumonia; the purpose of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76998-z
更新日期：2020-11-17 00:00:00
abstract：:Although recent studies focused on traditional Chinese medicine (TCM) for the treatment of refractory schizophrenia have reported that it may be beneficial, there is still lack of convincing evidence and critical meta-analytic work regarding its effectiveness as an adjunctive therapy. Therefore, we performed a meta-an...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析
doi：10.1038/s41598-018-24547-0
更新日期：2018-04-18 00:00:00
abstract：:Saccharomyces cerevisiae is a robust host for heterologous protein expression. The efficient expression of cellulases in S. cerevisiae is important for the consolidated bioprocess that directly converts lignocellulose into valuable products. However, heterologous proteins are often N-hyperglycosylated in S. cerevisiae...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25654
更新日期：2016-05-09 00:00:00
abstract：:Invasive alien species are regarded a nuisance. This extends into a lack of conservation efforts in their native range. As a consequence, conservation of e.g. range-edge populations is neglected. Gobiidae have many representatives of alien species in European freshwaters, and therefore they have a bad reputation. Obje...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56264-7
更新日期：2019-12-23 00:00:00
abstract：:Bio-functionalized nanoparticles with semiconducting/metallic core encapsulated in a bio- or bio-derived materials are promising for applications in biology and especially in cancer diagnostic and healing. In this report, we report a facile, single-step, first-time synthesis and in-situ functionalization strategy for ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18629
更新日期：2015-12-21 00:00:00
abstract：:This corrects the article DOI: 10.1038/srep30212. ...
journal_title：Scientific reports
pub_type： 杂志文章,已发布勘误
doi：10.1038/srep46831
更新日期：2017-05-26 00:00:00
abstract：:Breast cancer survivors display altered inflammatory responses to immune challenges relative to cancer-naive controls likely due to previous cancer treatments, stress associated with cancer, and/or tumor physiology. Proper inflammatory responses are necessary for adaptive sickness behaviors (e.g., fatigue, anorexia, a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37334-8
更新日期：2019-01-24 00:00:00
abstract：:Crystalline materials exhibit long-range ordered lattice unit, within which resides nonperiodic structural features called defects. These crystallographic defects play a vital role in determining the physical and mechanical properties of a wide range of material systems. While computer vision has demonstrated success ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49105-0
更新日期：2019-09-04 00:00:00
abstract：:Respiratory sensations such as breathlessness are prevalent in many diseases and are amplified by increased levels of anxiety. Cortical activation in response to inspiratory occlusions in high- and low-anxious individuals was found different in previous studies using the respiratory-related evoked potential method. Ho...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-51396-2
更新日期：2019-10-21 00:00:00
abstract：:Identifying communities in complex networks is an effective means for analyzing complex systems, with applications in diverse areas such as social science, engineering, biology and medicine. Finding communities of nodes and finding communities of links are two popular schemes for network analysis. These schemes, howev...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08638
更新日期：2015-03-02 00:00:00
abstract：:Partial thrombosis of the false lumen in uncomplicated type B aortic dissection (uTBAD) is associated with an increased late mortality risk. Whether the serum cortisol level can affect false lumen thrombosis in patients with uTBAD has not been well characterized. This study was performed on 87 patients with uTBAD. A c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-19691-6
更新日期：2018-01-19 00:00:00
abstract：:Meromictic lakes are useful biogeochemical models because of their stratified chemical gradients and separation of redox reactions down the water column. Perennially ice-covered meromictic lakes are particularly stable, with long term constancy in their density profiles. Here we sampled Lake A, a deep meromictic lake ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00604
更新日期：2012-01-01 00:00:00
abstract：:A novel dinuclear Ir(III) complex 5 was discovered to be specific to G-quadruplex DNA, and was utilized in a label-free G-quadruplex-based detection platform for transcription factor activity. The principle of this assay was demonstrated by using HIF-1α as a model protein. Moreover, this HIF-1α detection assay exhibit...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22458
更新日期：2016-03-02 00:00:00
abstract：:Because of the lack of cell wall, Micoplasma species require a fine control of membrane fluidity and integrity. mg517 is an essential gene of Mycoplasma genitalium responsible for the biosynthesis of membrane glycoglycerolipids. It encodes for a unique glycosyltransferase (MG517) with processive activity, transferring...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-42970-9
更新日期：2019-05-08 00:00:00
abstract：:Zika virus (ZIKV) is an emerging mosquito-borne pathogen representing a global health concern. It has been linked to fetal microcephaly and other birth defects and neurological disorders in adults. Sanofi Pasteur has engaged in the development of an inactivated ZIKV vaccine, as well as a live chimeric vaccine candidat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-31375-9
更新日期：2018-09-04 00:00:00
abstract：:In this study, an interval optimization model is developed to maximize the benefits of a water rights transfer system that comprises industry and agriculture sectors in the Ningxia Hui Autonomous Region in China. The model is subjected to a number of constraints including water saving potential from agriculture and ec...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02734-9
更新日期：2017-06-14 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-32119-5
更新日期：2018-09-11 00:00:00
abstract：:The iron binding capacities (IBC) of fulvic acid (FA) and humic acid (HA) were determined in the salinity range from 5 to 40. The results indicated that IBC decreased while salinity increased. In addition, dissolved iron (dFe), FA and HA were also determined along the Yangtze River estuary's increasing salinity gradie...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-01533-6
更新日期：2017-05-03 00:00:00
abstract：:Layered-structure materials are currently relevant given their quasi-2D nature. Knowledge of their physical properties is currently of major interest. Niobium ditelluride possesses a monoclinic layered-structure with a distortion in the tellurium planes. This structural complexity has hindered the determination of its...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35308-4
更新日期：2018-11-19 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-60910-w
更新日期：2020-02-28 00:00:00
abstract：:The integrity of the corticospinal tract (CST) is significantly affected following basal ganglia haemorrhage. We aimed to assess the local features of CST and to effectively predict motor function by diffusion characteristics of CST in patients with motor injury following acute haemorrhage in the acute basal ganglia r...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73305-8
更新日期：2020-10-01 00:00:00
abstract：:Recently, it has been shown that under pressure, unexpected and counterintuitive chemical compounds become stable. Laser shock experiments (A. Rode, unpublished) on alumina (Al2O3) have shown non-equilibrium decomposition of alumina with the formation of free Al and a mysterious transparent phase. Inspired by these ob...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09518
更新日期：2015-04-01 00:00:00
abstract：:Several studies have advanced the idea that the etiology of Alzheimer's disease (AD) could be microbial in origin. In the present study, we tested the possibility that polymicrobial infections exist in tissue from the entorhinal cortex/hippocampus region of patients with AD using immunohistochemistry (confocal laser s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05903-y
更新日期：2017-07-17 00:00:00
