Corrigendum: Lysine Acetylation and Succinylation in HeLa Cells and their Essential Roles in Response to UV-induced Stress.

abstract：:Plasma proteins such as fibrinogen induce the aggregation of red blood cells (RBC) into rouleaux, which are responsible for the pronounced shear thinning behavior of blood, control the erythrocyte sedimentation rate (ESR) - a common hematological test - and are involved in many situations of physiological relevance su...

journal_title：Scientific reports

authors： Flormann D,Aouane O,Kaestner L,Ruloff C,Misbah C,Podgorski T,Wagner C

更新日期：2017-08-11 00:00:00

abstract：:Many behaviors of cancer, such as progression, metastasis and drug resistance etc., cannot be fully understood by genetic mutations or intracellular signaling alone. Instead, they are emergent properties of the cell community which forms a tumor. Studies of tumor heterogeneity reveal that many cancer behaviors critica...

journal_title：Scientific reports

authors： Zhou JX,Taramelli R,Pedrini E,Knijnenburg T,Huang S

更新日期：2017-08-18 00:00:00

abstract：:Hepadnaviruses, including human hepatitis B virus (HBV), replicate their tiny DNA genomes by protein-primed reverse transcription of a pregenomic (pg) RNA. Replication initiation as well as pgRNA encapsidation depend on the interaction of the viral polymerase, P protein, with the ε RNA element, featuring a lower and a...

journal_title：Scientific reports

authors： Gajer M,Dörnbrack K,Rösler C,Schmid B,Beck J,Nassal M

更新日期：2017-08-02 00:00:00

abstract：:The concentration of CO2 in many aquatic systems is variable, often lower than the KM of the primary carboxylating enzyme Rubisco, and in order to photosynthesize efficiently, many algae operate a facultative CO2 concentrating mechanism (CCM). Here we measured the responses of a marine diatom, Thalassiosira pseudonana...

journal_title：Scientific reports

authors： Clement R,Lignon S,Mansuelle P,Jensen E,Pophillat M,Lebrun R,Denis Y,Puppo C,Maberly SC,Gontero B

更新日期：2017-02-09 00:00:00

abstract：:Luteinizing hormone (LH) is one of the main pituitary hormones that regulate ovulation, however its role has not been studied in giant panda. In this study, we developed an ELISA method for the detection of panda urinary LH. We analyzed urinary hormones of 24 female pandas during 36 breeding periods, we found females ...

journal_title：Scientific reports

authors： Cai K,Yie S,Zhang Z,Wang J,Cai Z,Luo L,Liu Y,Wang H,Huang H,Wang C,Huang X,Lan J,Hou R

更新日期：2017-01-16 00:00:00

abstract：:The Pax3/7 transcription factor family is integral to developmental gene networks contributing to important innovations in vertebrate evolution, including the neural crest. The basal chordate lineage of amphioxus is ideally placed to understand the dynamics of the gene regulatory network evolution that produced these ...

journal_title：Scientific reports

authors： Barton-Owen TB,Ferrier DEK,Somorjai IML

更新日期：2018-06-20 00:00:00

abstract：:The psychrophilic (cold-loving) fungus Pseudogymnoascus destructans was discovered more than a decade ago to be the pathogen responsible for white-nose syndrome, an emerging disease of North American bats causing unprecedented population declines. The same species of fungus is found in Europe but without associated mo...

journal_title：Scientific reports

authors： Ren P,Rajkumar SS,Zhang T,Sui H,Masters PS,Martinkova N,Kubátová A,Pikula J,Chaturvedi S,Chaturvedi V

更新日期：2020-08-17 00:00:00

abstract：:Hepatic steatosis (HS) can exacerbate acute pancreatitis (AP). This study aimed to investigate the relation between α1-antitrypsin (AAT) and acute pancreatitis when patients have HS. Using proteomic profiling, we identified 18 differently expressed proteins pots in the serum of rats with or without HS after surgical e...

journal_title：Scientific reports

authors： Wang Q,Du J,Yu P,Bai B,Zhao Z,Wang S,Zhu J,Feng Q,Gao Y,Zhao Q,Liu C

更新日期：2015-12-04 00:00:00

abstract：:Deforestation associated with the initial settlement of New Zealand is a dramatic example of how humans can alter landscapes through fire. However, evidence linking early human presence and land-cover change is inferential in most continental sites. We employed a multi-proxy approach to reconstruct anthropogenic land ...

journal_title：Scientific reports

authors： Argiriadis E,Battistel D,McWethy DB,Vecchiato M,Kirchgeorg T,Kehrwald NM,Whitlock C,Wilmshurst JM,Barbante C

更新日期：2018-08-14 00:00:00

abstract：:Although accumulating evidence indicates that both β-catenin and osterix (Osx) are essential for bone and tooth development, few studies have investigated the interaction of these two key proteins in the context of cementogenesis. In this study, we used transgenic mice with constitutively active β-catenin and inactive...

journal_title：Scientific reports

authors： Choi H,Kim TH,Yang S,Lee JC,You HK,Cho ES

更新日期：2017-08-15 00:00:00

abstract：:Infrared detection devices are becoming miniature with micro or nano-scale size. The advantages of downsizing come on the expense of insufficient collection of infrared radiation. Therefore, utilizing nano-plasmonic optical antennas becomes mandatory. However, it is desirable to develop antennas with broad bandwidth, ...

journal_title：Scientific reports

authors： Awad E

更新日期：2019-08-21 00:00:00

abstract：:Cell-matrix adhesions are of great interest because of their contribution to numerous biological processes, including cell migration, differentiation, proliferation, survival, tissue morphogenesis, wound healing, and tumorigenesis. Adhesions are dynamic structures that are classically defined on two-dimensional (2D) s...

journal_title：Scientific reports

authors： Broussard JA,Diggins NL,Hummel S,Georgescu W,Quaranta V,Webb DJ

更新日期：2015-01-29 00:00:00

abstract：:One of the famous results of network science states that networks with heterogeneous connectivity are more susceptible to epidemic spreading than their more homogeneous counterparts. In particular, in networks of identical nodes it has been shown that network heterogeneity, i.e. a broad degree distribution, can lower ...

journal_title：Scientific reports

authors： Yang H,Tang M,Gross T

更新日期：2015-08-21 00:00:00

abstract：:Society's increasing interactions with technology are creating extensive "digital traces" of our collective human behavior. These new data sources are fuelling the rapid development of the new field of computational social science. To investigate user attention to the Hurricane Sandy disaster in 2012, we analyze data ...

journal_title：Scientific reports

authors： Preis T,Moat HS,Bishop SR,Treleaven P,Stanley HE

更新日期：2013-11-05 00:00:00

abstract：:Adapters bind motor proteins to cargoes and therefore play essential roles in Kinesin-1 mediated intracellular transport. The regulatory mechanisms governing adapter functions and the spectrum of cargoes recognized by individual adapters remain poorly defined. Here, we show that cargoes transported by the Kinesin-1 ad...

journal_title：Scientific reports

authors： Butkevich E,Härtig W,Nikolov M,Erck C,Grosche J,Urlaub H,Schmidt CF,Klopfenstein DR,Chua JJ

更新日期：2016-06-01 00:00:00

abstract：:The synthesis and subsequent genomic integration of DNA that is complementary to the genomes of non-retroviral RNA viruses are rarely observed. However, upon infection of various human cell lines and primary fibroblasts with the vesicular stomatitis virus (VSV), we detected DNA complementary to the VSV RNA. The VSV DN...

journal_title：Scientific reports

authors： Shimizu A,Nakatani Y,Nakamura T,Jinno-Oue A,Ishikawa O,Boeke JD,Takeuchi Y,Hoshino H

更新日期：2014-05-30 00:00:00

abstract：:Tyrosine hydroxylase (TH), the initial enzyme in the melanin pathway, catalyzes tyrosine conversion into Dopa. Although expression and regulation of TH have been shown to affect cuticle pigmentation in insects, no direct functional studies to date have focused on the specific physiological processes involving the enzy...

journal_title：Scientific reports

authors： Qiao L,Du M,Liang X,Hao Y,He X,Si F,Mei T,Chen B

更新日期：2016-07-15 00:00:00

abstract：:In this work, Ni nanoparticles were directly decorated on graphene (G) nanosheets via mechanical ball milling. Based on transmission electron microscopy observations, the Ni nanoparticles were well dispersed and attached to the G nanosheet without any agglomerations. Electrochemical results showed that the capacitance...

journal_title：Scientific reports

authors： Mohd Zaid NA,Idris NH

更新日期：2016-08-24 00:00:00

abstract：:The distinguishing of the multiphoton quantum interference effect from the classical one forms one of the most important issues in modern quantum mechanics and experimental quantum optics. For a long time, the two-photon interference (TPI) of correlated photons has been recognized as a pure quantum effect that cannot ...

journal_title：Scientific reports

authors： Kim H,Kwon O,Moon HS

更新日期：2019-12-05 00:00:00

abstract：:We generated self-induced retinal ganglion cells (RGCs) with functional axons from human induced pluripotent stem cells. After development of the optic vesicle from the induced stem cell embryoid body in three-dimensional culture, conversion to two-dimensional culture, achieved by supplementation with BDNF, resulted i...

journal_title：Scientific reports

authors： Tanaka T,Yokoi T,Tamalu F,Watanabe S,Nishina S,Azuma N

更新日期：2015-02-10 00:00:00

abstract：:Detection of sedimentary cycles is difficult in fine-grained or homogenous sediments but is a prerequisite for the interpretation of depositional environments. Here we use a new autocorrelation analysis to detect cycles in a homogenous sediment core, E602, from the northern shelf of the South China Sea. Autocorrelatio...

journal_title：Scientific reports

authors： Xiao S,Li R,Chen M

更新日期：2013-01-01 00:00:00

abstract：:The primary hurdle for diagnosis of some diseases is the long incubation required to culture and confirm the presence of bacteria. The concept of using microbial VOCs as "signature markers" could provide a faster and noninvasive diagnosis. Finding biomarkers is challenging due to the specificity required in complex ma...

journal_title：Scientific reports

authors： Maurer DL,Ellis CK,Thacker TC,Rice S,Koziel JA,Nol P,VerCauteren KC

更新日期：2019-08-20 00:00:00

abstract：:The detection and assessment of leakage in retinal fluorescein angiogram images is important for the management of a wide range of retinal diseases. We have developed a framework that can automatically detect three types of leakage (large focal, punctate focal, and vessel segment leakage) and validated it on images fr...

journal_title：Scientific reports

authors： Zhao Y,MacCormick IJ,Parry DG,Leach S,Beare NA,Harding SP,Zheng Y

更新日期：2015-06-01 00:00:00

abstract：:The use of metabolomic and lipidomic strategies for selecting potential biomarkers for obstructive sleep apnoea (OSA) has been little explored. We examined adult male patients with OSA (defined by an apnoea-hypopnoea index ≥15 events/hour), as well as age-, gender-, and fat-composition-matched volunteers without OSA. ...

journal_title：Scientific reports

authors： Lebkuchen A,Carvalho VM,Venturini G,Salgueiro JS,Freitas LS,Dellavance A,Martins FC,Lorenzi-Filho G,Cardozo KHM,Drager LF

更新日期：2018-07-26 00:00:00

abstract：:Hepatic metabolic stability is a key pharmacokinetic parameter in drug discovery. Metabolic stability is usually assessed in microsomal fractions and only the best compounds progress in the drug discovery process. A high-throughput single time point substrate depletion assay in rat liver microsomes (RLM) is employed a...

journal_title：Scientific reports

authors： Siramshetty VB,Shah P,Kerns E,Nguyen K,Yu KR,Kabir M,Williams J,Neyra J,Southall N,Nguyễn ÐT,Xu X

更新日期：2020-11-26 00:00:00

abstract：:α-synuclein (aS) is a natively unfolded pre-synaptic protein found in all Parkinson's disease patients as the major component of fibrillar plaques. Metal ions, and especially Cu(II), have been demonstrated to accelerate aggregation of aS into fibrillar plaques, the precursors to Lewy bodies. In this work, copper bindi...

journal_title：Scientific reports

authors： Rose F,Hodak M,Bernholc J

更新日期：2011-01-01 00:00:00

abstract：:The advent of random start protocols to shorten the time needed to store oocytes in women with malignancies has represented an important improvement in the field of fertility preservation. However, Randomized Controlled Trials are difficult to implement in this area and available evidence that supports this approach r...

journal_title：Scientific reports

authors： Filippi F,Somigliana E,Busnelli A,Guarneri C,Noli S,Restelli L,Vercellini P

更新日期：2020-06-22 00:00:00

abstract：:In this study, we report on a new approach for remote temperature probing that provides accuracy as good as 0.017°C (0.0055% accuracy) by measuring the magnetisation curve of magnetic nanoparticles. We included here the theoretical model construction and the inverse calculation method, and explored the impact caused b...

journal_title：Scientific reports

authors： Zhong J,Liu W,Kong L,Morais PC

更新日期：2014-10-15 00:00:00

abstract：:We present detailed investigations on single crystals of quaternary EuRhAl4Si2 and EuIrAl4Si2. The two compounds order antiferromagnetically at TN1 = 11.7 and 14.7 K, respectively, each undergoing two magnetic transitions. The magnetic properties in the ordered state present a large anisotropy despite Eu(2+)being an S...

journal_title：Scientific reports

authors： Maurya A,Thamizhavel A,Dhar SK,Bonville P

更新日期：2015-07-09 00:00:00

abstract：:Globally, Aedes aegypti is one of the most dangerous mosquitoes that plays a crucial role as a vector for human diseases, such as yellow fever, dengue, and chikungunya. To identify (1) transcriptomic basis of midgut (2) key genes that are involved in the toxicity process by a comparative transcriptomic analysis betwee...

journal_title：Scientific reports

authors： Batool K,Alam I,Wu S,Liu W,Zhao G,Chen M,Wang J,Xu J,Huang T,Pan X,Yu X,Guan X,Xu L,Zhang L

更新日期：2018-08-23 00:00:00