Automated analysis of cell-matrix adhesions in 2D and 3D environments.

abstract：:Soft ferromagnetic Fe-based bulk metallic glass key-shaped specimens with a maximum and minimum width of 25.4 and 5 mm, respectively, were successfully produced using a high pressure die casting (HPDC) method, The influence of die material, alloy temperature and flow rate on the microstructure, thermal stability and s...

journal_title：Scientific reports

authors： Ramasamy P,Szabo A,Borzel S,Eckert J,Stoica M,Bárdos A

更新日期：2016-10-11 00:00:00

abstract：:Mounting evidence indicated that human mesenchymal stem cells (hMSCs) are responsive not only to biochemical but also to physical cues, such as substrate topography and stiffness. To simulate the dynamic structures of extracellular environments of the marrow in vivo, we designed a novel surrogate substrate for marrow ...

journal_title：Scientific reports

authors： Frank V,Kaufmann S,Wright R,Horn P,Yoshikawa HY,Wuchter P,Madsen J,Lewis AL,Armes SP,Ho AD,Tanaka M

更新日期：2016-04-15 00:00:00

abstract：:The vast majority of proteins do not form functional interactions in physiological conditions. We have considered several sets of protein pairs from S. cerevisiae with no functional interaction reported, denoted as non-interacting pairs, and compared their 3D structures to available experimental complexes. We identifi...

journal_title：Scientific reports

authors： Launay G,Ceres N,Martin J

更新日期：2017-01-13 00:00:00

abstract：:The aesthetic value of landscapes contributes to human well-being. However, studies which have investigated the link between biodiversity and ecosystem services have not taken aesthetic value into account. In this study we evaluated how the aesthetics of coralligenous reefs, a key marine ecosystem in the Mediterranean...

journal_title：Scientific reports

authors： Tribot AS,Mouquet N,Villéger S,Raymond M,Hoff F,Boissery P,Holon F,Deter J

更新日期：2016-09-28 00:00:00

abstract：:Early fMRI studies suggested that brain areas processing self-related and other-related information were highly overlapping. Hypothesising functional localisation of the cortex, researchers have tried to locate "self-specific" and "other-specific" regions within these overlapping areas by subtracting suspected confoun...

journal_title：Scientific reports

authors： Chen YA,Huang TR

更新日期：2017-03-03 00:00:00

abstract：:Metastasis suppressor genes (MS genes) are genes that play important roles in inhibiting the process of cancer metastasis without preventing growth of the primary tumor. Identification of these genes and understanding their functions are critical for investigation of cancer metastasis. Recent studies on cancer metasta...

journal_title：Scientific reports

authors： Zhao M,Li Z,Qu H

更新日期：2015-10-21 00:00:00

abstract：:Biomarkers of Huntington's disease (HD) in cerebrospinal fluid (CSF) could be of value in elucidating the biology of this genetic neurodegenerative disease, as well as in the development of novel therapeutics. Deranged synaptic and immune function have been reported in HD, and concentrations of the synaptic protein ne...

journal_title：Scientific reports

authors： Byrne LM,Rodrigues FB,Johnson EB,De Vita E,Blennow K,Scahill R,Zetterberg H,Heslegrave A,Wild EJ

更新日期：2018-03-09 00:00:00

abstract：:The fine-tuning of gene expression contributes to both basic science and applications. Here, we develop a novel gene expression technology termed CRITGI (CRISPR/Transposon gene integration). CRITGI uses CRISPR/Cas9 to integrate multiple copies of the plasmid pTy1 into Ty1 loci, budding yeast retrotransposons. The pTy1...

journal_title：Scientific reports

authors： Hanasaki M,Masumoto H

更新日期：2019-10-25 00:00:00

abstract：:The properties of the human mind affect the quality of scientific knowledge through the insertion of unconscious biases during the research process. These biases frequently cause overestimation of the effects under study, thereby violating the reproducibility of the research and potentially leading to incorrect conclu...

journal_title：Scientific reports

authors： Zvereva EL,Kozlov MV

更新日期：2021-01-08 00:00:00

abstract：:In a globalized world, plant invasions are common challenges for native ecosystems. Although a considerable number of invasive plants form arbuscular mycorrhizae, interactions between arbuscular mycorrhizal (AM) fungi and invasive and native plants are not well understood. In this study, we conducted a greenhouse expe...

journal_title：Scientific reports

authors： Řezáčová V,Řezáč M,Gryndlerová H,Wilson GWT,Michalová T

更新日期：2020-11-20 00:00:00

abstract：:Calcified marine organisms typically experience increased oxidative stress and changes in mineralization in response to ocean acidification and warming conditions. These effects could hinder the potency of animal weapons, such as the mantis shrimp's raptorial appendage. The mechanical properties of this calcified weap...

journal_title：Scientific reports

authors： deVries MS,Webb SJ,Tu J,Cory E,Morgan V,Sah RL,Deheyn DD,Taylor JR

更新日期：2016-12-15 00:00:00

abstract：:Uterine carcinosarcomas (UCSs) are highly aggressive malignancies associated with poor prognoses and limited treatment options. These tumors are hypothesized to develop from the endometrial adenocarcinoma (EAC) through epithelial-mesenchymal transition (EMT). We test this long-standing hypothesis by depleting miR-200,...

journal_title：Scientific reports

authors： Tseng JH,Bisogna M,Hoang LN,Olvera N,Rodriguez-Aguayo C,Lopez-Berestein G,Sood AK,Levine DA,Jelinic P

更新日期：2017-06-15 00:00:00

abstract：:Ultraviolet (UV) B radiation is a dangerous environmental stressor, which can lead to photoaging, inflammation, immune suppression and tumour formation. A recent report has shown the transcriptional activation of several skin-specific genes including matrix metalloproteases (MMPs) in response to UV irradiation. Here, ...

journal_title：Scientific reports

authors： Ujfaludi Z,Tuzesi A,Majoros H,Rothler B,Pankotai T,Boros IM

更新日期：2018-02-08 00:00:00

abstract：:Positions of leaves along a stem usually adhere to a genetically determined, species-specific pattern known as a leaf phyllotaxis. We investigated whether the arrangement of lateral secondary veins along primary midveins adhered to a species-specific pattern that resembled an alternate or opposite phyllotaxis. We anal...

journal_title：Scientific reports

authors： Koyama K,Masuda T

更新日期：2018-11-06 00:00:00

abstract：:Despite the fact that 2015 was the international year of light, no mention was made of the fact that radiation contains entropy as well as energy, with different spectral distributions. Whereas the energy function has been vastly studied, the radiation entropy distribution has not been analysed at the same speed. The ...

journal_title：Scientific reports

authors： Delgado-Bonal A

更新日期：2017-05-10 00:00:00

abstract：:Increasing life expectancy and a growing share of older people around the world spotlight the issue of health during additional years of life. Research on trends of proportions of older people with activity limitations for low and middle income countries is sparse. We use data from the World Health Survey and the UN W...

journal_title：Scientific reports

authors： Weber D,Scherbov S

更新日期：2020-06-26 00:00:00

abstract：:We quantitatively evaluated breast tumor movement and volume changes between magnetic resonance imaging (MRI) scans in prone and supine positions. Twenty-seven breast tumor patients who received neoadjuvant systemic therapy (NST) for breast-conserving surgery were studied. Before and after NST, MRI scans in prone and ...

journal_title：Scientific reports

authors： Wang CB,Lee S,Kim T,Hong D,Kim GB,Yoon GY,Kim HH,Kim N,Ko B

更新日期：2020-03-17 00:00:00

abstract：:In eukaryotes, RNA silencing, mediated by small interfering RNAs, is an evolutionarily widespread and versatile silencing mechanism that plays an important role in various biological processes. Increasing evidences suggest that various components of RNA silencing pathway are involved in plant defense machinery against...

journal_title：Scientific reports

authors： Uddin MN,Akhter S,Chakraborty R,Baek JH,Cha JY,Park SJ,Kang H,Kim WY,Lee SY,Mackey D,Kim MG

更新日期：2017-08-29 00:00:00

abstract：:Fibrosis-related events play a part in most blinding diseases worldwide. However, little is known about the mechanisms driving this complex multifactorial disease. Here we have carried out the first genome-wide RNA-Sequencing study in human conjunctival fibrosis. We isolated 10 primary fibrotic and 7 non-fibrotic conj...

journal_title：Scientific reports

authors： Yu-Wai-Man C,Owen N,Lees J,Tagalakis AD,Hart SL,Webster AR,Orengo CA,Khaw PT

更新日期：2017-07-17 00:00:00

abstract：:C-phycocyanin (C-PC) pigment, as a natural blue dye, has particular applications in various fields. It is a water-soluble protein which has anticancer, antioxidant and anti-inflammatory properties. Here, we introduce an efficient procedure for the purification of C-PC pigment, followed by conducting a comprehensive in...

journal_title：Scientific reports

authors： Safaei M,Maleki H,Soleimanpour H,Norouzy A,Zahiri HS,Vali H,Noghabi KA

更新日期：2019-07-01 00:00:00

abstract：:Plutella xylostella has become the major lepidopteran pest of Brassica owing to its strong ability of resistance development to a wide range of insecticides. Destruxin A, a mycotoxin of entomopathogenic fungus, Metarhizium anisopliae, has broad-spectrum insecticidal effects. However, the interaction mechanism of destr...

journal_title：Scientific reports

authors： Shakeel M,Xu X,Xu J,Zhu X,Li S,Zhou X,Yu J,Xu X,Hu Q,Yu X,Jin F

更新日期：2017-09-08 00:00:00

abstract：:Measuring the Parathyroid hormone (PTH) levels assists in the investigation and management of patients with parathyroid disorders. Rapid PTH monitoring is a valid tool for accurate assessment intraoperatively. Rapid Electro-Analytical Device (READ) is a point-of-care device that uses impedance change between target an...

journal_title：Scientific reports

authors： Tanak AS,Muthukumar S,Hashim IA,Prasad S

更新日期：2020-11-02 00:00:00

abstract：:With the development of ultra-intense laser technology, MeV ions can be obtained from laser-foil interactions in the laboratory. These energetic ion beams can be applied in fast ignition for inertial confinement fusion, medical therapy, and proton imaging. However, these ions are mainly accelerated in the laser propag...

journal_title：Scientific reports

authors： Wang W,Shen B,Zhang X,Zhang L,Shi Y,Xu Z

更新日期：2015-02-05 00:00:00

abstract：:Evaluations of restoration success usually focus on the structural aspects of ecosystems. Pollination, as an important functional aspect, is often overlooked. Here, the shifts in pollinator assemblage and pollen limitation in the desert shrub Caragana microphylla were examined along a restoration gradient in Horqin Sa...

journal_title：Scientific reports

authors： Pan CC,Qu H,Feng Q,Liu LD,Zhao HL,Li YL,Li YQ,Zhang TH,Liu XP

更新日期：2017-12-04 00:00:00

abstract：:The impact of HULC rs7763881 on colorectal cancer (CRC) susceptibility is not yet known. Also, the biological function of the cancer-related rs6983267 remains unclear. We investigated the association of these SNPs with the risk of CRC and adenomatous polyps (AP), their correlation with CCAT2 and HULC expression, and t...

journal_title：Scientific reports

authors： Shaker OG,Senousy MA,Elbaz EM

更新日期：2017-11-24 00:00:00

abstract：:Respiratory Distress Syndrome (RDS) is the commonest diagnosis after premature birth. We aimed to audit clinical practices before and after introduction of a national guideline in Wales on RDS management. Anonymised, prospective data on all infants born at <34 weeks of gestation and cared for at one of the participati...

journal_title：Scientific reports

authors： Course C,Chakraborty M

更新日期：2020-02-26 00:00:00

abstract：:This work describes a simple technique to produce porous ceramics with aligned porosity having very high permeability and specific surface area. SiOC-based compositions were processed from blends of three types of preceramic polymer and a catalyst, followed by curing and pyrolysis. The heating applied from the bottom ...

journal_title：Scientific reports

authors： Vakifahmetoglu C,Zeydanli D,Innocentini MD,Ribeiro FD,Lasso PR,Soraru GD

更新日期：2017-01-20 00:00:00

abstract：:We have sequenced the genome of the largest freshwater fish species of the world, the arapaima. Analysis of gene family dynamics and signatures of positive selection identified genes involved in the specific adaptations and unique features of this iconic species, in particular it's large size and fast growth. Genome s...

journal_title：Scientific reports

authors： Du K,Wuertz S,Adolfi M,Kneitz S,Stöck M,Oliveira M,Nóbrega R,Ormanns J,Kloas W,Feron R,Klopp C,Parrinello H,Journot L,He S,Postlethwait J,Meyer A,Guiguen Y,Schartl M

更新日期：2019-03-28 00:00:00

abstract：:Diagnosis and treatment of vocal fold lesions has been a long-evolving science for the otolaryngologist. Contemporary practice requires biopsy of a glottal lesion in the operating room under general anesthesia for diagnosis. Current in-office technology is limited to visualizing the surface of the vocal folds with fib...

journal_title：Scientific reports

authors： Coughlan CA,Chou LD,Jing JC,Chen JJ,Rangarajan S,Chang TH,Sharma GK,Cho K,Lee D,Goddard JA,Chen Z,Wong BJ

更新日期：2016-03-10 00:00:00

abstract：:Variations in isotopic composition of water vapor in the atmosphere is an important indicator of the processes within the hydrological cycle. Isotopic signature of water vapor and precipitation can be helpful in partitioning evaporation and transpiration fluxes. It is well known that transpiration from forested region...

journal_title：Scientific reports

authors： Pradhan R,Singh N,Singh RP

更新日期：2019-12-09 00:00:00