Abstract:
:Diagnosis and treatment of vocal fold lesions has been a long-evolving science for the otolaryngologist. Contemporary practice requires biopsy of a glottal lesion in the operating room under general anesthesia for diagnosis. Current in-office technology is limited to visualizing the surface of the vocal folds with fiber-optic or rigid endoscopy and using stroboscopic or high-speed video to infer information about submucosal processes. Previous efforts using optical coherence tomography (OCT) have been limited by small working distances and imaging ranges. Here we report the first full field, high-speed, and long-range OCT images of awake patients' vocal folds as well as cross-sectional video and Doppler analysis of their vocal fold motions during phonation. These vertical-cavity surface-emitting laser source (VCSEL) OCT images offer depth resolved, high-resolution, high-speed, and panoramic images of both the true and false vocal folds. This technology has the potential to revolutionize in-office imaging of the larynx.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Coughlan CA,Chou LD,Jing JC,Chen JJ,Rangarajan S,Chang TH,Sharma GK,Cho K,Lee D,Goddard JA,Chen Z,Wong BJdoi
10.1038/srep22792subject
Has Abstractpub_date
2016-03-10 00:00:00pages
22792issn
2045-2322pii
srep22792journal_volume
6pub_type
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