Abstract：
:Plasma proteins such as fibrinogen induce the aggregation of red blood cells (RBC) into rouleaux, which are responsible for the pronounced shear thinning behavior of blood, control the erythrocyte sedimentation rate (ESR) - a common hematological test - and are involved in many situations of physiological relevance such as structuration of blood in the microcirculation or clot formation in pathological situations. Confocal microscopy is used to characterize the shape of RBCs within rouleaux at equilibrium as a function of macromolecular concentration, revealing the diversity of contact zone morphology. Three different configurations that have only been partly predicted before are identified, namely parachute, male-female and sigmoid shapes, and quantitatively recovered by numerical simulations. A detailed experimental and theoretical analysis of clusters of two cells shows that the deformation increases nonlinearly with the interaction energy. Models indicate a forward bifurcation in which the contacting membrane undergoes a buckling instability from a flat to a deformed contact zone at a critical value of the interaction energy. These results are not only relevant for the understanding of the morphology and stability of RBC aggregates, but also for a whole class of interacting soft deformable objects such as vesicles, capsules or cells in tissues.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Flormann D,Aouane O,Kaestner L,Ruloff C,Misbah C,Podgorski T,Wagner Cdoi
10.1038/s41598-017-07634-6subject
Has Abstractpub_date
2017-08-11 00:00:00pages
7928issue
1issn
2045-2322pii
10.1038/s41598-017-07634-6journal_volume
7pub_type
杂志文章abstract：:Building resilience into today's complex infrastructures is critical to the daily functioning of society and its ability to withstand and recover from natural disasters, epidemics, and cyber-threats. This study proposes quantitative measures that capture and implement the definition of engineering resilience advanced ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19540
更新日期：2016-01-19 00:00:00
abstract：:We propose a novel method to achieve tunable plasmon focusing in graphene/photonic-crystal hybrid structure exhibiting all-angle negative refraction at terahertz frequencies. A two-dimensional photonic crystal composed of a square lattice of dielectric rods is constructed on the substrate of a graphene sheet to provid...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41788
更新日期：2017-02-02 00:00:00
abstract：:The marine bacterial strain Desulfovibrio ferrophilus IS5, known for its lithotrophic growth ability to use metallic iron as a sole electron donor and for causing corrosion of steel, was used in the current study. Four commonly used biocides in the oil and gas industry, namely tetrakis(hydroxymethyl) phosphonium sulfa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34789-7
更新日期：2018-11-09 00:00:00
abstract：:Marine biofouling can cause a biocorrosion, resulting in degradation and failure of materials and structures. In order to prevent sea creatures from attaching to the surface, in this work, a new environmentally friendly antifouling coating by incorporating antibacterial polymers and natural antifouling agents has been...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67073-8
更新日期：2020-06-25 00:00:00
abstract：:The time evolution of the distribution and shareability of quantum coherence of a tripartite system in a non-Markovian environment is examined. The total coherence can be decomposed into various contributions, ranging from local, global bipartite and global tripartite, which characterize the type of state. We identify...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39027-2
更新日期：2019-02-20 00:00:00
abstract：:Grafting of commercial tomato varieties and hybrids on the tomato ecotype Manduria resulted in high levels of tolerance to the infection of Sw5 resistance-breaking strains of tomato spotted wilt virus and of severe cucumber mosaic virus strains supporting hypervirulent satellite RNAs that co-determine stunting and nec...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59421-5
更新日期：2020-02-13 00:00:00
abstract：:Atlantic bluefin tuna (Thunnus thynnus) from the two main spawning populations in the Mediterranean and Gulf of Mexico occur together in the western, central and eastern Atlantic. Stock composition of catches from mixing areas is uncertain, presenting a major challenge to the sustainable management of the fisheries. T...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71355-6
更新日期：2020-09-07 00:00:00
abstract：:The compound Sr0.5Ce0.5FBiS2 belongs to the intensively studied family of layered BiS2 superconductors. It attracts special attention because superconductivity at T sc = 2.8 K was found to coexist with local-moment ferromagnetic order with a Curie temperature T C = 7.5 K. Recently it was reported that upon replacing...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17637-y
更新日期：2017-12-12 00:00:00
abstract：:Rett syndrome (RTT) is a neurodevelopmental disorder mainly caused by mutations in the gene encoding the transcriptional regulator Methyl-CpG-binding protein 2 (MeCP2), located on the X chromosome. Many RTT patients have breathing abnormalities, such as apnea and breathing irregularity, and respiratory infection is th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12293-8
更新日期：2017-09-20 00:00:00
abstract：:Cell therapy using intramuscular injections of autologous bone-marrow mononuclear cells (BM-MNCs) improves clinical symptoms and can prevent limb amputation in atherosclerotic peripheral arterial disease (PAD) patients with critical limb ischemia (CLI). The purpose of this study was to evaluate the effects of the numb...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76886-6
更新日期：2020-11-16 00:00:00
abstract：:The new π-extended redox-active ligand with both TTF and triazole units, 6-(4,5-bis(propylthio)-1,3-dithiol-2-ylidene)-1H-[1,3]dithiolo[4',5':4,5]benzo [1,2-d] [1-3]triazole, has been successfully prepared. Based on the versatile ligand and Cu(tta)2 precursors (tta(-) = 4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dion...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25544
更新日期：2016-05-06 00:00:00
abstract：:The sex-determining gene SRY induces SOX9 expression in the testes of eutherian mammals via two pathways. SRY binds to testis-specific enhancer of Sox9 (TESCO) with SF1 to activate SOX9 transcription. SRY also up-regulates ER71 expression, and ER71 activates Sox9 transcription. After the initiation of testis different...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep32874
更新日期：2016-09-09 00:00:00
abstract：:Changes in main volatile compounds of Chinese liquor after high pressure (HP) treatment and following short term storage were investigated. 400 MPa-15 min & 400 MPa-30 min were applied to young liquor. Results from gas chromatography (GC) analysis revealed decreasing trends in alcohols, aldehydes and ethyl acetate imm...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17549-x
更新日期：2017-12-08 00:00:00
abstract：:Molecular chaperones assist proteins in achieving a functional structure and prevent them from misfolding into aggregates, including disease-associated deposits. The BRICHOS domain from familial dementia associated protein Bri2 (or ITM2B) probably chaperones its specific proprotein region with high β-sheet propensity ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66718-y
更新日期：2020-06-17 00:00:00
abstract：:Ultrafine-grained die-upset Nd-Fe-B magnets are of importance because they provide a wide researching space to redesign the textured structures. Here is presented a route to obtain a new die-upset magnet with substantially improved magnetic properties. After experiencing the optimized heat treatment, both the coercivi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38335
更新日期：2016-12-06 00:00:00
abstract：:The Klein tunneling of optical waves near the Dirac points in the metal-dielectric multilayer metamaterials is theoretically investigated and demonstrated through the coupled-mode theory under the tight-binding approximation and the rigorous band structure analysis based on the transfer-matrix method. The optical anal...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09899-3
更新日期：2017-08-29 00:00:00
abstract：:Drug-resistant tuberculosis (TB) is a serious global problem, and pathogen factors involved in the transmission of isoniazid (INH)-resistant TB have not been fully investigated. We performed whole genome sequencing of 332 clinical Mycobacterium tuberculosis (Mtb) isolates collected from patients newly diagnosed with s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-51812-7
更新日期：2019-10-25 00:00:00
abstract：:Flight initiation distance (FID), a measure of an animal's tolerance to human disturbance and a descriptor of its fear of humans, is increasingly employed for conservation purposes and to predict the response of species to urbanization. However, most work devoted to understanding variability in FID has been conducted ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31060
更新日期：2016-08-08 00:00:00
abstract：:HIV-1 env sequencing enables predictions of viral coreceptor tropism and phylogenetic investigations of transmission events. The aim of the study was to estimate the contribution of non-R5 strains to the viral spread in Poland. Partial proviral env sequences were retrieved from baseline blood samples of patients with ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41407-7
更新日期：2019-03-21 00:00:00
abstract：:Schizophrenia is a highly heritable disorder with multiple susceptibility genes. Previously, we identified CACNA1C rs2007044 as a new risk locus for schizophrenia, with the minor allele G as risk allele. This association was recently validated by a powerful genome-wide association study. However, the underlying neural...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34298
更新日期：2016-09-29 00:00:00
abstract：:In a standard semiconductor laser, electrons and holes recombine via stimulated emission to emit coherent light, in a process that is far from thermal equilibrium. Exciton-polariton condensates-sharing the same basic device structure as a semiconductor laser, consisting of quantum wells coupled to a microcavity-have b...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25655
更新日期：2016-05-19 00:00:00
abstract：:Pseudomonas aeruginosa is an opportunistic pathogen that thrives in diverse environments and causes a variety of human infections. Pseudomonas aeruginosa AG1 (PaeAG1) is a high-risk sequence type 111 (ST-111) strain isolated from a Costa Rican hospital in 2010. PaeAG1 has both blaVIM-2 and blaIMP-18 genes encoding for...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-70581-2
更新日期：2020-08-13 00:00:00
abstract：:Photoacoustic tomography (PAT) offers three-dimensional (3D) structural and functional imaging of living biological tissue with label-free, optical absorption contrast. These attributes lend PAT imaging to a wide variety of applications in clinical medicine and preclinical research. Despite advances in live animal ima...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01113
更新日期：2013-01-01 00:00:00
abstract：:Photosynthetic activity is indispensable for plant growth and survival and it depends on the synthesis of plastidial isoprenoids as chlorophylls and carotenoids. In the non-mevalonate pathway (MEP), the 1-deoxy-D-xylulose-5-phosphate synthase 1 (DXS1) enzyme has been postulated to catalyze the rate-limiting step in th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45333
更新日期：2017-03-28 00:00:00
abstract：:Previous observational studies supported a positive association of glycated hemoglobin A1c (HbA1c) level with serum triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). However, the causal relationship between HbA1c and either one of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41076-6
更新日期：2019-04-02 00:00:00
abstract：:The spectral properties of Fano resonance generated in multilayer dielectric gratings (MDGs) are reported and numerically investigated in this paper. We examine the MDG consisting of numerous identically alternative chalcogenide glass (As2S3) and silica (SiO2) multilayers with several grating widths inscribed through ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34787-9
更新日期：2018-11-06 00:00:00
abstract：:Alterations in the gut microbiome have been reported in liver cirrhosis, and probiotic interventions are considered a potential treatment strategy. This study aimed to evaluate the effects and mechanisms of Lactobacillus salivarius LI01, Pediococcus pentosaceus LI05, Lactobacillus rhamnosus GG, Clostridium butyricum M...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07091-1
更新日期：2017-07-31 00:00:00
abstract：:The ubiquitously expressed aryl hydrocarbon receptor (AhR) induces drug metabolizing enzymes as well as regulators of cell growth, differentiation and apoptosis. Certain AhR ligands promote atherosclerosis, an age-associated vascular disease. Therefore, we investigated the role of AhR in vascular functionality and agi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19618
更新日期：2016-01-21 00:00:00
abstract：:Agricultural land is typically managed based on visible plant life at the expense of the belowground majority. However, microorganisms mediate processes sustaining plant life and the soil environment. To understand the role of microbes we first must understand what controls soil microbial community assembly. We assess...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45369
更新日期：2017-03-28 00:00:00
abstract：:Strategies adopted by individuals in a social network significantly impact the network, and they strongly affect relationships between individuals in the network. Links between individuals also heavily influence their levels of cooperation. Taking into account the evolution of each individual's connection, we explore ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45237
更新日期：2017-03-24 00:00:00
