Abstract：
:This systematic review and meta-analysis was designed to investigate whether maternal psychological stress and recent life events are associated with an increased risk of miscarriage. A literature search was conducted to identify studies reporting miscarriage in women with and without history of exposure to psychological stress (the only exposure considered). The search produced 1978 studies; 8 studies were suitable for analysis. A meta-analysis was performed using a random-effects model with effect sizes weighted by the sampling variance. The risk of miscarriage was significantly higher in women with a history of exposure to psychological stress (OR 1.42, 95% CI 1.19-1.70). These findings remained after controlling for study type (cohort and nested case-control study OR 1.33 95% CI 1.14-1.54), exposure types (work stress OR 1.27, 95% CI 1.10-1.47), types of controls included (live birth OR 2.82 95% CI: 1.64-4.86). We found no evidence that publication bias or study heterogeneity significantly influenced the results. Our finding provides the most robust evidence to date, that prior psychological stress is harmful to women in early pregnancy.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Qu F,Wu Y,Zhu YH,Barry J,Ding T,Baio G,Muscat R,Todd BK,Wang FF,Hardiman PJdoi
10.1038/s41598-017-01792-3subject
Has Abstractpub_date
2017-05-11 00:00:00pages
1731issue
1issn
2045-2322pii
10.1038/s41598-017-01792-3journal_volume
7pub_type
杂志文章,meta分析abstract：:The regeneration of WPAC through pyrolysis and its adsorption capacity of phosphorus were studied. The optimum conditions for WPAC regeneration were 650 °C and 2 h which resulted in a recovery of BET surface and total pore volume with a value of 1161.4 m2/g and 1.2176 m3/g. WPAC had a maximum PO43--P adsorption capaci...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-19131-x
更新日期：2018-01-15 00:00:00
abstract：:Stored-product psocids (Psocoptera: Liposcelididae) are cosmopolitan storage pests that can damage stored products and cause serious economic loss. However, because of the body size (~1 mm) of eggs, nymphs, and adults, morphological identification of most stored-product psocids is difficult and hampers effective ident...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16888-z
更新日期：2017-12-01 00:00:00
abstract：:Dorso-ventral (DV) countershading is a highly-conserved pigmentary adaptation in vertebrates. In mammals, spatially regulated expression of agouti-signaling protein (ASIP) generates the difference in shading by driving a switch between the production of chemically-distinct melanins in melanocytes in dorsal and ventral...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40251-z
更新日期：2019-03-05 00:00:00
abstract：:The overpopulation of abandoned and stray companion animals has become a global crisis. The main purpose of this study was to develop a novel nanomedicine-based antifertility compound for non-surgical castration of male animals. Mangosteen (Garcinia mangostana L) pericarp extract has been shown to exhibit anti-fertili...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16563-3
更新日期：2017-11-24 00:00:00
abstract：:Interleukin-27 (IL-27) is an important cytokine in inflammatory diseases, including coronary artery disease (CAD). To explore the precise role of IL-27 in CAD, we investigated the genetic association between IL27 and CAD in the GeneID Chinese Han population. A two-stage case control association analysis was performed ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25782
更新日期：2016-05-12 00:00:00
abstract：:Receptor tyrosine kinases (RTKs) are key regulators of normal cellular processes and have a critical role in the development and progression of many diseases. RTK ligand-induced stimulation leads to activation of the cytoplasmic kinase domain that controls the intracellular signalling. Although the kinase domain of RT...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62460-7
更新日期：2020-03-25 00:00:00
abstract：:Sunitinib (ST), a multitargeted receptor tyrosine kinase inhibitor, has been demonstrated to be effective for the treatment of renal carcinoma. It has been reported that ST is involved in the mediation of autophagy; however, its regulatory role in the autophagic process remains controversial. Furthermore, the mechanis...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47597-4
更新日期：2019-07-31 00:00:00
abstract：:Knowledge of the structure-property-function relationship of humic substances (HSs) is key for understanding their role in soil. Despite progress, studies on this topic are still under discussion. We analyzed 37 humic fractions with respect to their isotopic composition, structural characteristics, and properties resp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20798
更新日期：2016-02-10 00:00:00
abstract：:Although oxide-based resistive switching memory (OxRAM) is one of the strong next-generation high capacity memory candidates, it has the critical disadvantage that deviations of resistance levels is too severe to be adopted as a high capacity memory device. More specifically, it is known that the larger on/off current...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35838-x
更新日期：2019-01-22 00:00:00
abstract：:The aim of the study was to investigate the role of endogenous sulfur dioxide (SO2)/ aspartate aminotransferase 1 (AAT1) pathway in stretch-induced excessive collagen expression and its mechanism. The mechanical stretch downregulated SO2/AAT1 pathway and increased collagen I and III protein expression. Importantly, AA...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep21112
更新日期：2016-02-16 00:00:00
abstract：:A single radiation-induced superoxide ion [Formula: see text] has been observed for the first time in metal oxides. This structural defect has been revealed in fast-neutron-irradiated (6.9×1018 n/cm2) corundum (α-Al2O3) single crystals using the EPR method. Based on the angular dependence of the EPR lines at the magne...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72958-9
更新日期：2020-09-28 00:00:00
abstract：:Shoulder apprehension is more complex than a pure mechanical problem of the shoulder, creating a scar at the brain level that prevents the performance of specific movements. Surgery corrects for shoulder instability at the physical level, but a re-dislocation within the first year is rather common. Predicting which pa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00518-9
更新日期：2017-03-29 00:00:00
abstract：:The rise of antibiotic resistance (AMR) is one of the most important public health threats worldwide.Today, increasing attention is being paid to multidrug resistant staphylococci isolated from healthcare and non-healthcare environments as the treatment of these bacteria has become increasingly difficult. In this stud...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45886-6
更新日期：2019-08-01 00:00:00
abstract：:Sapphirinid copepods, which are marine zooplankton, exhibit tunable structural colors originating from a layered structure of guanine crystal plates. In the present study, the coloring portion of adult male of a sapphirinid copepod, Sapphirina nigromaculata, under the dorsal body surface was characterized to clarify t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59090-4
更新日期：2020-02-10 00:00:00
abstract：:Delivering and expressing a gene of interest in cells or living animals has become a pivotal technique in biomedical research and gene therapy. Among viral delivery systems, adeno-associated viruses (AAVs) are relatively safe and demonstrate high gene transfer efficiency, low immunogenicity, stable long-term expressio...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49624-w
更新日期：2019-09-19 00:00:00
abstract：:Heterogeneity is inherent to biology, thus it is imperative to realize methods capable of obtaining spatially-resolved genomic and transcriptomic profiles of heterogeneous biological samples. Here, we present a new method for local lysis of live adherent cells for nucleic acid analyses. This method addresses bottlenec...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29579
更新日期：2016-07-14 00:00:00
abstract：:Immunoglobulin A nephropathy (IgAN) involves repeated events of gross haematuria with concurrent upper airway infections. The mucosal immune system, especially the tonsil, is considered the initial site of inflammation, although the role of the tonsillar microbiota has not been established in IgAN. In this study, we c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73035-x
更新日期：2020-10-01 00:00:00
abstract：:Membrane proteins are distinguished from soluble proteins by their insertion into biological membranes. This insertion is achieved via a noticeable arrangement of hydrophobic amino acids that are exposed at the surface of the protein, and renders the interaction with the aliphatic tails of lipids more energetically fa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17216-1
更新日期：2017-12-05 00:00:00
abstract：:The significance of antibodies directed against paternal epitopes in the context of obstetric disorders is discussed controversially. In this study anti-HLA and anti-MIC-A antibodies were analysed in sera of women with uneventful pregnancy (n = 101), preeclampsia (PE, n = 55) and gestational diabetes (GDM, n = 36) usi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13275-6
更新日期：2017-10-19 00:00:00
abstract：:Tropical deforestation is responsible for around one tenth of total anthropogenic carbon emissions, and tropical protected areas (PAs) that reduce deforestation can therefore play an important role in mitigating climate change and protecting biodiversity and ecosystem services. While the effectiveness of PAs in reduci...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14467-w
更新日期：2017-10-25 00:00:00
abstract：:Primordial germ cells (PGCs), the embryonic precursors of the sperm and egg, are used for the introduction of genetic modifications into avian genome. Introduction of small defined sequences using genome editing has not been demonstrated in bird species. Here, we compared oligonucleotide-mediated HDR using wild type S...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33244-x
更新日期：2018-10-11 00:00:00
abstract：:Biological N2 fixation (BNF) in the rhizosphere of Podocarpaceae is currently attributed to unspecific diazotrophs with negligible impact on N acquisition. Here, we report specific and high associative BNF in dead cells of root nodules of Lepidothamnus fonkii distributed in ombrotrophic peatlands of Patagonia. BNF of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39072
更新日期：2016-12-15 00:00:00
abstract：:To begin studies on reproduction in common bed bug, Cimex lectularius, we identified three genes coding for vitellogenin (Vg, a protein required for the reproductive success of insects) and studied their hormonal regulation. RNA interference studied showed that expression of Vg3 gene in the adult females is a prerequi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35546
更新日期：2016-10-20 00:00:00
abstract：:The optical gain and spontaneous emission characteristics of low In-content AlInN-delta-GaN quantum wells (QWs) are analyzed for deep ultraviolet (UV) light emitting diodes (LEDs) and lasers. Our analysis shows a large increase in the dominant transverse electric (TE) polarized spontaneous emission rate and optical ga...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22983
更新日期：2016-03-10 00:00:00
abstract：:Umami taste perception indicates the presence of amino acids, which are essential nutrients. Although the physiology of umami perception has been described in mammals, how insects detect amino acids remains unknown except in Drosophila melanogaster. We functionally characterized a gustatory receptor responding to L-am...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46738-z
更新日期：2019-08-12 00:00:00
abstract：:The spin-transfer nano-oscillator (STNO) offers the possibility of using the transfer of spin angular momentum via spin-polarized currents to generate microwave signals. However, at present STNO microwave emission mainly relies on both large drive currents and external magnetic fields. These issues hinder the implemen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01426
更新日期：2013-01-01 00:00:00
abstract：:Working memory capacity is incredibly limited and thus it is important to use this resource wisely. Prior knowledge in long-term memory can aid in efficient encoding of information by allowing for the prioritization of novel stimuli over familiar ones. Here we used a full-report procedure in a visual working memory pa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79108-1
更新日期：2020-12-17 00:00:00
abstract：:Pore-forming toxins are the most common virulence factor in pathogenic bacteria. They lead to membrane permeabilization and cell death. Herein, we show that respiratory epithelial cells (REC) undergoing bacterial pore-forming toxin (PFT)-induced necroptosis simultaneously experienced caspase activation independently o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24210-8
更新日期：2018-04-11 00:00:00
abstract：:Stem and progenitor cells are the critical units for tissue maintenance, regeneration, and repair. The activation of regenerative events in response to tissue injury has been correlated with mobilization of tissue-resident progenitor cells, which is functional to the wound healing process. However, until now there has...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16574
更新日期：2015-11-12 00:00:00
abstract：:Sharp increase in macromolecular crowding induces abnormal chromatin compaction in the cell nucleus, suggesting its non-negligible impact on chromatin structure and function. However, the details of the crowding-induced chromatin compaction remain poorly understood. In this work, we present a computer simulation study...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23753-0
更新日期：2018-04-03 00:00:00
