Juvenile hormone regulation of female reproduction in the common bed bug, Cimex lectularius.

abstract：:Constrained by the diffraction limit, a lens can only resolve features larger than half of the incident wavelength owing to the decaying nature of evanescent waves. Several novel devices have been proposed, for example, superlenses and hyperlenses to break this limit. In this work, we present a flat hyperlens composed...

journal_title：Scientific reports

authors： Tao CW,Yen TJ,Huang TY

更新日期：2020-03-24 00:00:00

abstract：:Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the subjective criteria for evaluation. In this study, we propose a deep learning model tha...

journal_title：Scientific reports

authors： Wei JW,Tafe LJ,Linnik YA,Vaickus LJ,Tomita N,Hassanpour S

更新日期：2019-03-04 00:00:00

abstract：:Invasive fungal infections are a potentially life-threatening complication in immunocompromised patients. The aim of this study was to assess the efficacy and safety of posaconazole as compared with other antifungal agents for preventing invasive fungal infections in immunocompromised patients. Embase, CENTRAL, and ME...

journal_title：Scientific reports

authors： Wong TY,Loo YS,Veettil SK,Wong PS,Divya G,Ching SM,Menon RK

更新日期：2020-09-03 00:00:00

abstract：:This study was initiated to improve E. coli succinate production by engineering the E. coli global transcription factor, Cra (catabolite repressor/activator). Random mutagenesis libraries were generated through error-prone PCR of cra. After re-screening and mutation site integration, the best mutant strain was Tang154...

journal_title：Scientific reports

authors： Zhu LW,Xia ST,Wei LN,Li HM,Yuan ZP,Tang YJ

更新日期：2016-11-04 00:00:00

abstract：:Extensive research indicates that inter-sexual selection drives the evolution of complex vocal communication in birds, but parallel lines of evidence are almost entirely absent in mammals. This dearth of evidence, particularly among primates, limits our understanding of the link between sociality and vocal complexity....

journal_title：Scientific reports

authors： Gustison ML,Bergman TJ

更新日期：2016-01-21 00:00:00

abstract：:Low pH in the tumor micromilieu is a recognized pathological feature of cancer. This attribute of cancerous cells has been targeted herein for the controlled release of chemotherapeutics at the tumour site, while sparing healthy tissues. To this end, pH-sensitive, hollow ZnO-nanocarriers loaded with paclitaxel were sy...

journal_title：Scientific reports

authors： Puvvada N,Rajput S,Kumar BNP,Sarkar S,Konar S,Brunt KR,Rao RR,Mazumdar A,Das SK,Basu R,Fisher PB,Mandal M,Pathak A

更新日期：2015-07-06 00:00:00

abstract：:We investigate optical bound states in the continuum (BICs) supported by a photonic crystal (PhC) slab penetrated with periodic annular holes theoretically. Ultrahigh-quality factor (Q-factor) resonances associated with BICs are obtained with a Q-factor more than 108. The BICs can be seen at nonzero incident angles by...

journal_title：Scientific reports

authors： Li Z,Zhu Q,Wang Y,Xie S

更新日期：2018-08-20 00:00:00

abstract：:Nano-sized hydroxyapatite (n-HA) is considered as a bio-active material, which is often mixed into bone implant material, polyetheretherketone (PEEK). To reveal the global protein expression modulations of osteoblast in response to direct contact with the PEEK composite containing high level (40%) nano-sized hydroxyap...

journal_title：Scientific reports

authors： Zhao M,Li H,Liu X,Wei J,Ji J,Yang S,Hu Z,Wei S

更新日期：2016-03-09 00:00:00

abstract：:In a subendothelial space of atherosclerotic arteries, apolipoprotein B-containing lipoproteins are accumulated and oxidized, and the oxidized lipoproteins promote macrophage foam cell formation. Therefore, the analysis of vitamin E, a major antioxidant in lipoproteins, is important for understanding atherosclerotic p...

journal_title：Scientific reports

authors： Hirowatari Y,Yoshida H,Kurosawa H,Manita D,Tada N

更新日期：2014-02-13 00:00:00

abstract：:Vaginal delivery with obstetrical trauma is a risk factor for pelvic organ prolapse later in life. Loss of fibulin-5 (FBLN5), an elastogenesis-promoting cellular matrix protein, results in prolapse in mice. Here, we evaluated effects of pregnancy, parturition, and obstetrical injury on FBLN5 content, elastic fibers, b...

journal_title：Scientific reports

authors： Hamner J,Florian-Rodriguez M,Acevedo J,Shi H,Word RA

更新日期：2020-04-14 00:00:00

abstract：:Boreal forests play critical roles in global carbon, water and energy cycles. Recent studies suggest drought is causing a decline in boreal spruce growth, leading to predictions of widespread mortality and a shift in dominant vegetation type in interior Alaska. We took advantage of a large set of tree cores collected ...

journal_title：Scientific reports

authors： Sullivan PF,Pattison RR,Brownlee AH,Cahoon SMP,Hollingsworth TN

更新日期：2017-11-10 00:00:00

abstract：:Despite efforts during the past decades, loop modeling remains a difficult part of protein structure modeling. Several approaches have been developed in the framework of crystal structures. However, for homology models, the modeling of loops is still far from being solved. We propose DaReUS-Loop, a data-based approach...

journal_title：Scientific reports

authors： Karami Y,Guyon F,De Vries S,Tufféry P

更新日期：2018-09-12 00:00:00

abstract：:Naturally occurring metals and metalloids [metal(loid)s] are essential for the physiological functioning of wildlife; however, environmental contamination by metal(loid) and plastic pollutants is a health hazard. Metal(loid)s may interact with plastic in the environment and there is mixed evidence about whether plasti...

journal_title：Scientific reports

authors： Roman L,Kastury F,Petit S,Aleman R,Wilcox C,Hardesty BD,Hindell MA

更新日期：2020-10-22 00:00:00

abstract：:Adolescent idiopathic scoliosis (AIS) is the most common type of spinal deformity and has a significant genetic background. Genome-wide association studies (GWASs) identified several susceptibility loci associated with AIS. Among them is a locus on chromosome 6q24.1 that we identified by a GWAS in a Japanese cohort. T...

journal_title：Scientific reports

authors： Kou I,Watanabe K,Takahashi Y,Momozawa Y,Khanshour A,Grauers A,Zhou H,Liu G,Fan YH,Takeda K,Ogura Y,Zhou T,Iwasaki Y,Kubo M,Wu Z,Matsumoto M,Japan Scoliosis Clinical Research Group (JSCRG).,Texas Scottish Rite Hospital f

更新日期：2018-08-01 00:00:00

abstract：:The tricarboxylic acid cycle produces NADH for oxidative phosphorylation and fumarase [EC 4.2.1.2] is a critical enzyme in this cycle, catalysing the reversible conversion of fumarate and L-malate. Fumarase is applied to industrial L-malate production as a biocatalyst. L-malate is used in a wide range of industries su...

journal_title：Scientific reports

authors： Katayama N,Takeya M,Osanai T

更新日期：2019-07-23 00:00:00

abstract：:To study quantitatively replicative senescence as a tumor suppressor mechanism, we investigate the distribution of a growing clonal cell population restricted by Hayflick's limit. We find that in the biologically relevant range of parameters, if the imbalance between cell division and death is moderate or low (high de...

journal_title：Scientific reports

authors： Rodriguez-Brenes IA,Wodarz D,Komarova NL

更新日期：2015-12-09 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Shkarina S,Shkarin R,Weinhardt V,Melnik E,Vacun G,Kluger PJ,Loza K,Epple M,Ivlev SI,Baumbach T,Surmeneva MA,Surmenev RA

更新日期：2018-11-29 00:00:00

abstract：:The Mont-Blanc massif, being iconic with its large glaciers and peaks of over 4,000 m, will experience a sharp increase in summer temperatures during the twenty-first century. By 2100, the impact of climate change on the cryosphere and hydrosphere in the Alps is expected to lead to a decrease in annual river discharge...

journal_title：Scientific reports

authors： Laurent L,Buoncristiani JF,Pohl B,Zekollari H,Farinotti D,Huss M,Mugnier JL,Pergaud J

更新日期：2020-06-26 00:00:00

abstract：:We present a novel, non-invasive magnetic resonance imaging (MRI) technique to assess real-time dynamic vasomodulation of the microvascular bed. Unlike existing perfusion imaging techniques, our method is sensitive only to blood volume and not flow velocity. Using graded gas challenges and a long-life, blood-pool T 1-...

journal_title：Scientific reports

authors： Ganesh T,Estrada M,Yeger H,Duffin J,Cheng HL

更新日期：2017-08-07 00:00:00

abstract：:The prominent comprehensive properties of solid-solution- and intermetallic-based Ti alloys are derived from their diverse microstructures induced by multi-component alloying, which results in a chemical composition complexity. A cluster-plus-glue-atom model, characterizing the chemical short-range orders, was introdu...

journal_title：Scientific reports

authors： Jiang B,Wang Q,Dong C,Liaw PK

更新日期：2019-03-04 00:00:00

abstract：:Surgery and anesthesia induce inflammatory changes in the central nervous system, which ultimately lead to neuronal damage concomitant with an increase in the level of neurodegeneration markers. Despite some experimental data showing prolonged activation of the immune system post-surgery, no study has determined the e...

journal_title：Scientific reports

authors： DiMeglio M,Furey W,Hajj J,Lindekens J,Patel S,Acker M,Bavaria J,Szeto WY,Atluri P,Haber M,Diaz-Arrastia R,Laudanski K

更新日期：2019-05-09 00:00:00

abstract：:Quartz is a common phase in high-silica igneous rocks and is resistant to post-eruptive alteration, thus offering a reliable record of magmatic processes in silicic magma systems. Here we employ the 75 ka Toba super-eruption as a case study to show that quartz can resolve late-stage temporal changes in magmatic δ18O v...

journal_title：Scientific reports

authors： Budd DA,Troll VR,Deegan FM,Jolis EM,Smith VC,Whitehouse MJ,Harris C,Freda C,Hilton DR,Halldórsson SA,Bindeman IN

更新日期：2017-01-25 00:00:00

abstract：:The distribution of carbon from a branch setting pod in alfalfa was investigated during the seed development of seeds to determine the relative contribution of pod and leaf photoassimilates to the total C balance and to investigate the partitioning of these photoassimilates to other plant organs. A 13Clabeling procedu...

journal_title：Scientific reports

authors： Zhang W,Mao P,Li Y,Wang M,Xia F,Wang H

更新日期：2017-02-07 00:00:00

abstract：:Bose Einstein condensates of spin-1 atoms are known to exist in two different phases, both having spontaneously broken spin-rotation symmetry, a ferromagnetic and a polar condensate. Here we show that in two spatial dimensions it is possible to achieve a quantum phase transition from a polar condensate into a singlet ...

journal_title：Scientific reports

authors： Chudnovskiy AL,Cheianov V

更新日期：2018-08-20 00:00:00

abstract：:The 2,5-Diketopiperazines (DKPs) constitute a large family of natural products with important biological activities. Bicyclomycin is a clinically-relevant DKP antibiotic that is the first and only member in a class known to target the bacterial transcription termination factor Rho. It derives from cyclo-(L-isoleucyl-L...

journal_title：Scientific reports

authors： Witwinowski J,Moutiez M,Coupet M,Correia I,Belin P,Ruzzini A,Saulnier C,Caraty L,Favry E,Seguin J,Lautru S,Lequin O,Gondry M,Pernodet JL,Darbon E

更新日期：2019-12-27 00:00:00

abstract：:The self-cleaning property is usually connected to superhydrophobic surfaces (SHSs) where the dust particles can be easily removed by the rolling motion of droplets. It seems that superhydrophobicity (its durability is questionable nowadays) is a necessity. However here, it is disclosed that self-cleaning can also be ...

journal_title：Scientific reports

authors： Quan YY,Zhang LZ,Qi RH,Cai RR

更新日期：2016-12-05 00:00:00

abstract：:Range-wide population studies of wide spread species are often associated with complex diversity patterns resulting from genetically divergent evolutionary significant units (ESUs). The compound evolutionary history creating such a pattern of diversity can be inferred through molecular analyses. Asparagus cochinchinen...

journal_title：Scientific reports

authors： Lee SR,Park HS,Kim BY,Lee JH,Fan Q,Gaskin JF,Kim YD

更新日期：2019-07-05 00:00:00

abstract：:Herein, triphenyltin (TPT) biodegradation efficiency and its transformation pathway have been elucidated. To better understand the molecular mechanism of TPT degradation, the interactions between amino acids, primary structures, and quaternary conformations of effector proteins and TPT were studied. The results verifi...

journal_title：Scientific reports

authors： Wang L,Ye J,Ou H,Qin H,Long Y,Ke J

更新日期：2017-06-23 00:00:00

abstract：:Drug discovery efforts against the pathogen Mycobacterium tuberculosis (Mtb) have been advanced through phenotypic screens of extensive compound libraries. Such a screen revealed sulfolane 1 and indoline-5-sulfonamides 2 and 3 as potent inhibitors of mycobacterial growth. Optimization in the sulfolane series led to co...

journal_title：Scientific reports

authors： Abrahams KA,Cox JAG,Fütterer K,Rullas J,Ortega-Muro F,Loman NJ,Moynihan PJ,Pérez-Herrán E,Jiménez E,Esquivias J,Barros D,Ballell L,Alemparte C,Besra GS

更新日期：2017-08-25 00:00:00

abstract：:Case-control genetic association studies typically ignore possible later disease onset in currently healthy subjects and assume that subjects with diseases equally contribute to the likelihood for inference, regardless of their onset age. Therefore, we used an event-history with risk-free model to simultaneously chara...

journal_title：Scientific reports

authors： Yang HC,Chen IC,Tsay YC,Li ZR,Chen CH,Hwu HG,Chen CH

更新日期：2017-05-16 00:00:00