Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint.

Abstract:

:Eugenol is a hydroxyphenyl propene, naturally occurring in the essential oils of several plants belonging to the Lamiaceae, Lauraceae, Myrtaceae, and Myristicaceae families. It is one of the major constituents of clove (Syzygium aromaticum (L.) Merr. & L.M. Perry, Myrtaceae) oil and is largely used in both foods and cosmetics as a flavoring agent. A large body of recent scientific evidence supports claims from traditional medicine that eugenol exerts beneficial effects on human health. These effects are mainly associated with antioxidant and anti-inflammatory activities. Eugenol has also shown excellent antimicrobial activity in studies, being active against fungi and a wide range of gram-negative and gram-positive bacteria. The aim of this review is to analyze scientific data from the main published studies describing the antibacterial and antifungal activities of eugenol targeting different kind of microorganisms, such as those responsible for human infectious diseases, diseases of the oral cavity, and food-borne pathogens. This article also reports the effects of eugenol on multi-drug resistant microorganisms. On the basis of this collected data, eugenol represents a very interesting bioactive compound with broad spectrum antimicrobial activity against both planktonic and sessile cells belonging to food-decaying microorganisms and human pathogens.

journal_name

Crit Rev Microbiol

authors

Marchese A,Barbieri R,Coppo E,Orhan IE,Daglia M,Nabavi SF,Izadi M,Abdollahi M,Nabavi SM,Ajami M

doi

10.1080/1040841X.2017.1295225

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

668-689

issue

6

eissn

1040-841X

issn

1549-7828

journal_volume

43

pub_type

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