abstract：:Biofilms are complex microbial architectures that encase microbial cells in a matrix comprising self-produced extracellular polymeric substances. Microorganisms living in biofilms are much more resistant to hostile environments than their planktonic counterparts and exhibit enhanced resistance against the microbicides...

journal_title：Critical reviews in microbiology

authors： Yin W,Xu S,Wang Y,Zhang Y,Chou SH,Galperin MY,He J

更新日期：2020-12-28 00:00:00

abstract：:The cell wall of Saccharomyces cerevisiae is an extracellular organelle crucial for preserving its cellular integrity and detecting environmental cues. The cell wall is composed of mannoproteins attached to a polysaccharide network and is continuously remodelled as cells undergo cell division, mating, gametogenesis or...

journal_title：Critical reviews in microbiology

authors： Novačić A,Vučenović I,Primig M,Stuparević I

更新日期：2020-02-01 00:00:00

abstract：:Due to the rise of multidrug-resistant infections in humans, phage therapy is gaining renewed attention in Western medicine. Despite the increasing number of publications focussed on the isolation, characterization and in vitro performance of different phages, there is still a lack of concise pre-clinical information ...

journal_title：Critical reviews in microbiology

authors： Melo LDR,Oliveira H,Pires DP,Dabrowska K,Azeredo J

更新日期：2020-02-01 00:00:00

abstract：:The exact aetiology of most autoimmune diseases remains unknown, nonetheless, several factors contributing to the induction or exacerbation of autoimmune reactions have been suggested. These include the genetic profile and lifestyle of the affected individual in addition to environmental triggers such as bacterial, pa...

journal_title：Critical reviews in microbiology

authors： Hussein HM,Rahal EA

更新日期：2019-08-01 00:00:00

abstract：:The immune system is well-equipped with sensors that detect invading pathogens and dictate subsequent immune responses for clearing the infections. One such class of sensor is the toll-like receptor (TLR), that can sense diverse molecules of pathogen origin such as proteins, lipids, carbohydrate, DNA, RNA, and trigger...

journal_title：Critical reviews in microbiology

authors： Udgata A,Dolasia K,Ghosh S,Mukhopadhyay S

更新日期：2019-05-01 00:00:00

abstract：:Microbially synthesized iron oxide nanoparticles (FeONPs) hold great potential for biomedical, clinical, and environmental applications owing to their several unique features. Biomineralization, a process that exists in almost every living organism playing a significant role in the fabrication of FeONPs through the in...

journal_title：Critical reviews in microbiology

authors： Ashraf N,Ahmad F,Da-Wei L,Zhou RB,Feng-Li H,Yin DC

更新日期：2019-05-01 00:00:00

abstract：:Antibiotic resistance in Gram-negative pathogens has emerged and constituted a global crisis, thereby novel antibiotics and other anti-infective strategies are urgently needed. However, the growing gap between clinical need and drug innovation, coupled with the membrane permeability barrier in Gram-negative bacteria r...

journal_title：Critical reviews in microbiology

authors： Liu Y,Li R,Xiao X,Wang Z

更新日期：2019-05-01 00:00:00

abstract：:Polymyxins are important lipopeptide antibiotics that serve as the last-line defense against multidrug-resistant (MDR) Gram-negative bacterial infections. Worryingly, the clinical utility of polymyxins is currently facing a serious threat with the global dissemination of mcr, plasmid-mediated polymyxin resistance. The...

journal_title：Critical reviews in microbiology

authors： Nang SC,Li J,Velkov T

更新日期：2019-03-01 00:00:00

abstract：:Industrialisation has introduced several lifestyle changes and medical advancements but their impact on intestinal microbiota acquisition is often overlooked. Even though these consequential changes in the microbiota could contribute to the disease burden that accompanies industrialisation, such as obesity and atopic ...

journal_title：Critical reviews in microbiology

authors： Van Daele E,Knol J,Belzer C

更新日期：2019-01-01 00:00:00

abstract：:Pathogens in soil play a tremendous role in soil health and subsequent food production. Soil-borne pathogens can cause serious losses to global harvest and are considered as a difficult problem to manage worldwide. The emergence of soil disease is largely dependent on the pathogen-host-environment complex, which can b...

journal_title：Critical reviews in microbiology

authors： Wang L,Li X

更新日期：2019-01-01 00:00:00

abstract：:Emerging infectious diseases remain among the leading causes of global mortality. Traditional laboratory diagnostic approaches designed to detect and track infectious disease agents provide a framework for surveillance of bio threats. However, surveillance and outbreak investigations using such time-consuming approach...

journal_title：Critical reviews in microbiology

authors： Bokhari H

更新日期：2018-08-01 00:00:00

abstract：:Nanotechnology has revolutionized almost all the fields of science and technology, particularly the food packaging industry. Accordingly, some nanoparticles can be used in food contact materials to preserve food products for longer periods. To date, many inorganic and metal nanoparticles have been implemented to synth...

journal_title：Critical reviews in microbiology

authors： Hoseinnejad M,Jafari SM,Katouzian I

更新日期：2018-03-01 00:00:00

abstract：:The numbers and diversity of microbes in ecosystems within and around us is unmatched, yet most of these microorganisms remain recalcitrant to in vitro cultivation. Various high-throughput molecular techniques, collectively termed multi-omics, provide insights into the genomic structure and metabolic potential as well...

journal_title：Critical reviews in microbiology

authors： Gutleben J,Chaib De Mares M,van Elsas JD,Smidt H,Overmann J,Sipkema D

更新日期：2018-03-01 00:00:00

abstract：:Escherichia coli can commonly be found, either as a commensal, probiotic or a pathogen, in the human gastrointestinal (GI) tract. Biofilm formation and its regulation is surprisingly variable, although distinct regulatory pattern of red, dry and rough (rdar) biofilm formation arise in certain pathovars and even clones...

journal_title：Critical reviews in microbiology

authors： Rossi E,Cimdins A,Lüthje P,Brauner A,Sjöling Å,Landini P,Römling U

更新日期：2018-02-01 00:00:00

abstract：:Antimicrobial resistance of disease-related microorganisms is considered a worldwide prevalent and serious issue which increases the failure of treatment outcomes and leads to high mortality. Considering that the increased resistance to systemic antimicrobial therapy often needs of the use of more toxic agents, topica...

journal_title：Critical reviews in microbiology

authors： Lam PL,Lee KKH,Wong RSM,Cheng GYM,Bian ZX,Chui CH,Gambari R

更新日期：2018-02-01 00:00:00

abstract：:Although bacteria have historically been considered to play a major role in cystic fibrosis (CF) airway damage, a strong impact of respiratory viral infections (RVI) is also now recognized. Emerging evidence confirms that respiratory viruses are associated with deterioration of pulmonary function and exacerbation and ...

journal_title：Critical reviews in microbiology

authors： Billard L,Le Berre R,Pilorgé L,Payan C,Héry-Arnaud G,Vallet S

更新日期：2017-11-01 00:00:00

abstract：:Eugenol is a hydroxyphenyl propene, naturally occurring in the essential oils of several plants belonging to the Lamiaceae, Lauraceae, Myrtaceae, and Myristicaceae families. It is one of the major constituents of clove (Syzygium aromaticum (L.) Merr. & L.M. Perry, Myrtaceae) oil and is largely used in both foods and c...

journal_title：Critical reviews in microbiology

authors： Marchese A,Barbieri R,Coppo E,Orhan IE,Daglia M,Nabavi SF,Izadi M,Abdollahi M,Nabavi SM,Ajami M

更新日期：2017-11-01 00:00:00

abstract：:Staphylococcus aureus biofilms represent a unique micro-environment that directly contribute to the bacterial fitness within hospital settings. The accumulation of this structure on implanted medical devices has frequently caused the development of persistent and chronic S. aureus-associated infections, which represen...

journal_title：Critical reviews in microbiology

authors： Figueiredo AMS,Ferreira FA,Beltrame CO,Côrtes MF

更新日期：2017-09-01 00:00:00

abstract：:Resuscitation promoting factors (Rpf) are peptidoglycan-hydrolyzing enzymes that are pivotal in the resuscitation of quiescent actinobacteria including Mycobacterium tuberculosis. From the published data, it is clear that Rpf are required for the resuscitation of non-replicating bacilli and pathogenesis in murine infe...

journal_title：Critical reviews in microbiology

authors： Rosser A,Stover C,Pareek M,Mukamolova GV

更新日期：2017-09-01 00:00:00

abstract：:Giardia lamblia is the causative agent of the diarrheal disease giardiasis, against which only a limited number of drugs are currently available. Increasing reports of resistance to these drugs makes it necessary to identify new cellular targets for designing the next generation of anti-giardial drugs. Towards this go...

journal_title：Critical reviews in microbiology

authors： Ray A,Sarkar S

更新日期：2017-08-01 00:00:00

abstract：:T-cells play an important role in immunity but when these cells are overexposed to specific antigens, their function may decline. This state is usually referred to as exhaustion and the T-cells show reduced proliferation and functions such as cytokine release. T-cell exhaustion has been observed in several cancers as ...

journal_title：Critical reviews in microbiology

authors： Khan N,Vidyarthi A,Amir M,Mushtaq K,Agrewala JN

更新日期：2017-03-01 00:00:00

abstract：:Riboflavin derivatives are essential cofactors for a myriad of flavoproteins. In bacteria, flavins importance extends beyond their role as intracellular protein cofactors, as secreted flavins are a key metabolite in a variety of physiological processes. Bacteria obtain riboflavin through the endogenous riboflavin bios...

journal_title：Critical reviews in microbiology

authors： García-Angulo VA

更新日期：2017-03-01 00:00:00

abstract：:Gonorrhea is a major, global public health problem for which there is no vaccine. The continuing emergence of antibiotic-resistant strains raises concerns that untreatable Neisseria gonorrhoeae may become widespread in the near future. Consequently, there is an urgent need for increased efforts towards the development...

journal_title：Critical reviews in microbiology

authors： Edwards JL,Jennings MP,Apicella MA,Seib KL

更新日期：2016-11-01 00:00:00

abstract：:The use of marine microorganisms as potential biofactories for green synthesis of metallic nanoparticles is a relatively new field of research with considerable prospects. This method is eco-friendly, time saving, and inexpensive and can be easily scaled up for large-scale synthesis. The increasing need to develop sim...

journal_title：Critical reviews in microbiology

authors： Manivasagan P,Nam SY,Oh J

更新日期：2016-11-01 00:00:00

abstract：:The use of phages to control and reduce numbers of unwanted bacteria can be traced back to the early 1900s, when phages were explored as a tool to treat infections before the wide scale use of antibiotics. Recently, phage therapy has received renewed interest as a method to treat multiresistant bacteria. Phages are al...

journal_title：Critical reviews in microbiology

authors： Krysiak-Baltyn K,Martin GJ,Stickland AD,Scales PJ,Gras SL

更新日期：2016-11-01 00:00:00

abstract：:Both coagulation and fibrinolysis are tightly connected with the innate immune system. Infection and inflammation cause profound alterations in the otherwise well-controlled balance between coagulation and fibrinolysis. Many pathogenic bacteria directly exploit the host's hemostatic system to increase their virulence....

journal_title：Critical reviews in microbiology

authors： Peetermans M,Vanassche T,Liesenborghs L,Lijnen RH,Verhamme P

更新日期：2016-11-01 00:00:00

abstract：:The brucellae are α-Proteobacteria causing brucellosis, an important zoonosis. Although multiplying in endoplasmic reticulum-derived vacuoles, they cause no cell death, suggesting subtle but efficient use of host resources. Brucellae are amino-acid prototrophs able to grow with ammonium or use glutamate as the sole ca...

journal_title：Critical reviews in microbiology

authors： Ronneau S,Moussa S,Barbier T,Conde-Álvarez R,Zuniga-Ripa A,Moriyon I,Letesson JJ

更新日期：2016-08-01 00:00:00

abstract：:The cyanobacteria (blue-green algae) are photosynthetic prokaryotes having applications in human health with numerous biological activities and as a dietary supplement. It is used as a food supplement because of its richness in nutrients and digestibility. Many cyanobacteria (Microcystis sp, Anabaena sp, Nostoc sp, Os...

journal_title：Critical reviews in microbiology

authors： Raja R,Hemaiswarya S,Ganesan V,Carvalho IS

更新日期：2016-05-01 00:00:00

abstract：:Within Gram-positive bacteria, the expression of target genes is controlled at the population level via signaling peptides, also known as pheromones. Pheromones control a wide range of functions, including competence, virulence, and others that remain unknown. Until now, their role in bacterial gene regulation has pro...

journal_title：Critical reviews in microbiology

authors： Monnet V,Juillard V,Gardan R

更新日期：2016-05-01 00:00:00

abstract：:The female genital tract is an intricate, yet balanced ecosystem that hosts a variety of different residential microflora. The physiological changes that occur during pregnancy may disrupt this balanced ecosystem and predispose women to a potentially pathogenic microbiota. Bacteria that are associated with bacterial v...

journal_title：Critical reviews in microbiology

authors： Redelinghuys MJ,Ehlers MM,Dreyer AW,Kock MM

更新日期：2016-05-01 00:00:00

abstract：:Legionella spp. are the causative agent of Legionnaire's disease and an opportunistic pathogen of significant public health concern. Identification and quantification from environmental sources is crucial for identifying outbreak origins and providing sufficient information for risk assessment and disease prevention. ...

journal_title：Critical reviews in microbiology

authors： Whiley H,Taylor M

更新日期：2016-01-01 00:00:00

abstract：:Re-emergence of resistance in different pathogens including viruses are the major cause of human disease and death, which is posing a serious challenge to the medical, pharmaceutical and biotechnological sectors. Though many efforts have been made to develop drug and vaccines against re-emerging viruses, researchers a...

journal_title：Critical reviews in microbiology

authors： Rai M,Deshmukh SD,Ingle AP,Gupta IR,Galdiero M,Galdiero S

更新日期：2016-01-01 00:00:00

abstract：:Heavy metal contamination has become a worldwide environmental concern due to its toxicity, non-degradability and food-chain bioaccumulation. Conventional physical and chemical treatment methods for heavy metal removal have disadvantages such as cost-intensiveness, incomplete removal, secondary pollution and the lack ...

journal_title：Critical reviews in microbiology

authors： Li PS,Tao HC

更新日期：2015-06-01 00:00:00

abstract：:The genus Aureobasidium spp. have been divided into three species, A. pullulans. A. leucospermi and A. proteae, and A. pullulans has been known to have five varieties. However, after analysis of many strains of this yeast isolated from different environments, they do not belong to any of the three species or the five ...

journal_title：Critical reviews in microbiology

authors： Li Y,Chi Z,Wang GY,Wang ZP,Liu GL,Lee CF,Ma ZC,Chi ZM

更新日期：2015-06-01 00:00:00

abstract：:Toxin-antitoxin (TA) systems consist of a bicistronic operon, encoding a toxin and an antitoxin. They are widely distributed in the prokaryotic kingdom, often in multiple numbers. TAs are implicated in contradicting phenomena of persistence and programmed cell death (PCD) in bacteria. mazEF TA system, one of the widel...

journal_title：Critical reviews in microbiology

authors： Ramisetty BC,Natarajan B,Santhosh RS

更新日期：2015-02-01 00:00:00

abstract：:Lectins are natural bioactive ubiquitous proteins or glycoproteins of non-immune response that bind reversibly to glycans of glycoproteins, glycolipids and polysaccharides possessing at least one non-catalytic domain causing agglutination. Some of them consist of several carbohydrate-binding domains which endow them w...

journal_title：Critical reviews in microbiology

authors： Singh RS,Thakur SR,Bansal P

更新日期：2015-02-01 00:00:00

abstract：:The increasing emergence of antimicrobial multiresistant bacteria is of great concern to public health. While these bacteria are becoming an ever more prominent cause of nosocomial and community-acquired infections worldwide, the antibiotic discovery pipeline has been stalled in the last few years with very few effort...

journal_title：Critical reviews in microbiology

authors： Cardona ST,Selin C,Gislason AS

更新日期：2015-01-01 00:00:00

abstract：:Tuberculosis (TB) is an air-born, transmissible disease, having an estimated 9.4 million new TB cases worldwide in 2009. Eventual control of this disease by developing a safe and efficient new vaccine able to detain its spread will have an enormous impact on public health policy. Selecting potential antigens to be inc...

journal_title：Critical reviews in microbiology

authors： Ocampo M,Patarroyo MA,Vanegas M,Alba MP,Patarroyo ME

更新日期：2014-05-01 00:00:00

abstract：:With the increase in antibiotic-resistant bacteria and the lack of new antibiotics being brought onto the market, alternative strategies need to be found to cope with infections resulting from drug-resistant bacteria. A possible solution may be to combine existing antibiotics with phytochemicals to enhance the efficac...

journal_title：Critical reviews in microbiology

authors： Langeveld WT,Veldhuizen EJ,Burt SA

更新日期：2014-02-01 00:00:00

abstract：:Macrophomina phaseolina (Tassi) Goid. is an important phytopathogenic fungus, infecting a large number of plant species and surviving for up to 15 years in the soil as a saprophyte. Although considerable research related to the biology and ecology of Macrophomina has been conducted, it continues to cause huge economic...

journal_title：Critical reviews in microbiology

authors： Kaur S,Dhillon GS,Brar SK,Vallad GE,Chand R,Chauhan VB

更新日期：2012-05-01 00:00:00