Biocompatible biodegradable polymeric antibacterial nanoparticles for enhancing the effects of a third-generation cephalosporin against resistant bacteria.

abstract：:Fifty-eight isolates of Shigella sonnei from three outbreaks in school children and eight control isolates from epidemiologically unrelated sporadic clinical infections in Taiwan were compared by antibiotic susceptibility testing and molecular typing. Antibiotic susceptibility testing showed that all strains except on...

journal_title：Journal of medical microbiology

authors： Lee TM,Chang LL,Chang CY,Wang JC,Pan TM,Wang TK,Chang SF

更新日期：2000-04-01 00:00:00

abstract：:Some strains of Helicobacter pylori are known to produce an extracellular cytotoxin that causes vacuolation in cultured mammalian cells. Screening for such strains makes use of HeLa cells which may not be sensitive enough to detect minimal changes. The aim of this study was to develop a more sensitive cell line. Vacuo...

journal_title：Journal of medical microbiology

authors： Wang XM,Kojima T,Satoh K,Taniguchi Y,Tokumaru K,Saifuku K,Seki M,Kihira K,Ido K,Uchida JY,Ohmori C,Takaoka T,Kimura K

更新日期：1997-08-01 00:00:00

abstract：PURPOSE:To analyse the role of virulence factors (VFs) and host in Klebsiella pneumoniae upper urinary tract infections (UTIs) in renal transplant (RTx) recipients. METHODOLOGY:Clinical and demographic data were registered prospectively. Phylogenetic background of K. pneumoniae isolates was analysed by PCR melting pro...

journal_title：Journal of medical microbiology

authors： Gołębiewska JE,Krawczyk B,Wysocka M,Ewiak A,Komarnicka J,Bronk M,Rutkowski B,Dębska-Ślizień A

更新日期：2019-03-01 00:00:00

abstract：:Clostridium perfringens has been reported as the cause of up to 15% of cases of antibiotic-associated diarrhoea (AAD) and may be diagnosed by detection of enterotoxin (CPEnt) in faeces. The performance of a commercial ELISA method for CPEnt, with culture and PCR methods to confirm the presence of enterotoxigenic C. pe...

journal_title：Journal of medical microbiology

authors： Asha NJ,Wilcox MH

更新日期：2002-10-01 00:00:00

abstract：:After the introduction of the dengue-2 (16681) virus by intradermal (i.d.) injection into the footpads of mice, Langerhans cells (LCs) increased in numbers within 24 h at the site of injection and neutralising antibody developed. On comparing the i.d. and intramuscular (i.m.) routes, antibody was produced more rapidly...

journal_title：Journal of medical microbiology

authors： Taweechaisupapong S,Sriurairatana S,Angsubhakorn S,Yoksan S,Khin MM,Sahaphong S,Bhamarapravati N

更新日期：1996-08-01 00:00:00

abstract：:The objectives of the present study were to evaluate in vitro the production of antagonistic compounds against Gardnerella vaginalis by Lactobacillus strains isolated from women with or without bacterial vaginosis (BV), and to select one of the better Lactobacillus producers of such a substance to be tested in vivo us...

journal_title：Journal of medical microbiology

authors： Teixeira GS,Carvalho FP,Arantes RME,Nunes AC,Moreira JLS,Mendonça M,Almeida RB,Farias LM,Carvalho MAR,Nicoli JR

更新日期：2012-08-01 00:00:00

abstract：:The present study aimed to characterize cell damage caused by vaginal Candida albicans isolates from women with different symptomatologies. It was evaluated 12 clinical isolates of C. albicans from vaginal samples: 4 from asymptomatic women (AS), 4 from women with a single episode of vulvovaginal candidiasis (VVC) and...

journal_title：Journal of medical microbiology

authors： Faria DR,Sakita KM,Akimoto-Gunther LS,Kioshima ÉS,Svidzinski TIE,Bonfim-Mendonça PS

更新日期：2017-08-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) exists as distinct variants HHV-6A and HHV-6B. The complete genomes of HHV-6A and HHV-6B have been sequenced. HHV-6B contains 97 unique genes. CD46 is the cell receptor for HHV-6, explaining its broad tissue tropism but its restricted host-species range. HHV-6 utilizes a number of strategie...

journal_title：Journal of medical microbiology

authors： Dockrell DH

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:We examined evidence for transmission of Pandorea apista among cystic fibrosis (CF) patients attending paediatric and adult services in one city who had previously been found to harbour related isolates by pulsed-field gel electrophoresis (PFGE). METHODOLOGY:The whole-genome sequences of 18 isolates from this ...

journal_title：Journal of medical microbiology

authors： Kenna DTD,Coward A,Perry C,Pike R,Schaefer U,Turton J,Green H,Jones AM,Bright-Thomas RJ,Burns P,Narayan O,Wilkinson S,Turton JF

更新日期：2019-07-01 00:00:00

abstract：:Recent studies have shown that Providencia alcalifaciens is a diarrhoeal pathogen. It may cause diarrhoea by an invasive mechanism, as it invades cultured mammalian cells in vitro and intestinal epithelial cells of experimentally inoculated rabbits in vivo. To locate the gene(s) involved in invasion, TnphoA mutants of...

journal_title：Journal of medical microbiology

authors： Rahman M,Monira S,Nahar S,Ansaruzzaman M,Alam K,Alam M,Albert MJ

更新日期：2002-08-01 00:00:00

abstract：:Francisella tularensis is a highly virulent intracellular bacterium capable of rapid multiplication in phagocytic cells. Previous studies have revealed that activation of F. tularensis-infected macrophages leads to control of infection and reactive nitrogen and oxygen species make important contributions to the bacter...

journal_title：Journal of medical microbiology

authors： Tancred L,Telepnev MV,Golovliov I,Andersson B,Andersson H,Lindgren H,Sjöstedt A

更新日期：2011-11-01 00:00:00

abstract：:The genetic diversity between major meticillin-resistant Staphylococcus aureus (MRSA) lineages was probed using fluorescent amplified fragment length polymorphism (FAFLP) as a random genome sampling tool. Genomic DNA was digested with endonucleases BglII and Csp6I and a subset of the restricted fragments were amplifie...

journal_title：Journal of medical microbiology

authors： Desai D,Ellington MJ,Arnold C,Desai M

更新日期：2012-12-01 00:00:00

abstract：:Sorbarod biofilms were investigated for their suitability in establishing continuous culture biofilms for the study of bacterial vaginosis. Two important organisms in the condition, Gardnerella vaginalis and Lactobacillus acidophilus, were studied. In contrast to growth in broth culture, both organisms were maintained...

journal_title：Journal of medical microbiology

authors： Muli FW,Struthers JK

更新日期：1998-05-01 00:00:00

abstract：:Yokenella regensburgei is an opportunistic human pathogen of the Enterobacteriaceae family rarely reported to cause human infections. Here, we present a case report of Y. regensburgei bacteraemia from India clinically resembling enteric fever in an apparently immunocompetent paediatric patient. ...

journal_title：Journal of medical microbiology

authors： Jain S,Gaind R,Gupta KB,Dawar R,Kumar D,Paul P,Sardana R,Deb M

更新日期：2013-06-01 00:00:00

abstract：:Various factors influencing the susceptibility of C3H mice to lethal infection by the phycomycete Absidia ramosa were examined. Mice 19-21 days old were exposed to graded doses of A. ramosa spores by various routes. After intravenous inoculation with doses in excess of 10(3) viable units, a variable proportion of mice...

journal_title：Journal of medical microbiology

authors： Corbel MJ,Eades SM

更新日期：1975-11-01 00:00:00

abstract：:Fusobacterium necrophorum, a Gram-negative anaerobe, causes a variety of necrotic infections in humans and animals. There are two subspecies: subsp. necrophorum and subsp. funduliforme. In cattle, subsp. necrophorum is more prevalent and production of leukotoxin is a major virulence factor. The leukotoxin operon (lktB...

journal_title：Journal of medical microbiology

authors： Tadepalli S,Stewart GC,Nagaraja TG,Narayanan SK

更新日期：2008-02-01 00:00:00

abstract：:Oral biofilms are one of the greatest challenges in dental research. The present study aimed to investigate initial bacterial colonization of enamel surfaces in situ using fluorescence in situ hybridization (FISH) over a 12 h period. For this purpose, bovine enamel slabs were fixed on buccal sites of individual splint...

journal_title：Journal of medical microbiology

authors： Al-Ahmad A,Follo M,Selzer AC,Hellwig E,Hannig M,Hannig C

更新日期：2009-10-01 00:00:00

abstract：:Of 2458 isolates of Haemophilus influenzae examined in a recent British survey, 42 were resistant to chloramphenicol. Two resistant isolates were of type b and 40 were non-capsulate. Spectrophotometric assay showed that all the resistant isolates produced chloramphenicol acetyltransferase (CAT). CAT activity did not i...

journal_title：Journal of medical microbiology

authors： Powell M,Livermore DM

更新日期：1988-10-01 00:00:00

abstract：:Chickens were immunised with a preparation of purified 14-kDa fimbriae of Salmonella serotype Enteritidis (SEF 14) to raise egg-yolk antibodies for protection trials in mice against subsequent challenge-exposure with the homologous strain of Enteritidis. A pronounced specificity of egg-yolk antibodies against the 14-k...

journal_title：Journal of medical microbiology

authors： Peralta RC,Yokoyama H,Ikemori Y,Kuroki M,Kodama Y

更新日期：1994-07-01 00:00:00

abstract：:Catalase (KatA) is known to play an important role in oxidative stress resistance in many bacterial species and a homologue exists in Helicobacter hepaticus, a member of the enterohepatic Helicobacter species. Here, a katA mutant was constructed by insertional mutagenesis and its oxidative stress phenotype was investi...

journal_title：Journal of medical microbiology

authors： Hong Y,Wang G,Maier RJ

更新日期：2007-04-01 00:00:00

abstract：:This study analysed the invasiveness of Listeria monocytogenes into enterocyte-like Caco-2 cells in which iron depletion was achieved by picolinic acid treatment. Both entry and intracellular multiplication varied depending on the endogenous iron content of bacterial and eukaryotic cells. The behaviour within enterocy...

journal_title：Journal of medical microbiology

authors： Conte MP,Longhi C,Petrone G,Polidoro M,Valenti P,Seganti L

更新日期：2000-08-01 00:00:00

abstract：:PCR-based detection of Mucorales species could improve diagnosis of suspected invasive fungal infection, leading to a better patient outcome. This study describes two independent probe-based real-time PCR tests for detection of clinically relevant Mucorales, targeting specific fragments of the 18S and the 28S rRNA gen...

journal_title：Journal of medical microbiology

authors： Springer J,Goldenberger D,Schmidt F,Weisser M,Wehrle-Wieland E,Einsele H,Frei R,Löffler J

更新日期：2016-03-01 00:00:00

abstract：:Limited digestion of staphylococcal enterotoxin B (SEB) with trypsin resulted in the generation of a 12-Kda amino-terminal fragment and a 17-Kda carboxy-terminal fragment which were isolated by preparative iso-electric focusing. The carboxy-terminal fragment exhibited significant mitogenic activity for murine splenocy...

journal_title：Journal of medical microbiology

authors： Binek M,Newcomb JR,Rogers CM,Rogers TJ

更新日期：1992-03-01 00:00:00

abstract：PURPOSE:Penicillium is the most common mould isolated in housing. Penicillium chrysogenum is the only species tested by prick test or serology for allergic patients. The American Institute of Medicine has accepted Penicillium as an aetiological agent of rhinitis in children and adults and as an asthma agent in children...

journal_title：Journal of medical microbiology

authors： Reboux G,Rocchi S,Vacheyrou M,Millon L

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:Listeria monocytogenes is a genetically heterogeneous species, which is divided into evolutionary lineages and clonal complexes (CCs). Not all L. monocytogenes isolates are equally likely to cause disease, with CC1, and in particular sequence type (ST) 1, being the most prevalent complex in human and ruminant i...

journal_title：Journal of medical microbiology

authors： Rupp S,Bärtschi M,Frey J,Oevermann A

更新日期：2017-07-01 00:00:00

abstract：:Introduction. Quantification of bacterial load in tissue homogenates in in vivo pharmacodynamic studies is cumbersome and time-consuming.Aim. We therefore developed a new method for quantifying bacterial load in tissue homogenates of animals treated with a β-lactam and β-lactamase inhibitor using growth curves.Methods...

journal_title：Journal of medical microbiology

authors： Georgiou PC,Mouton JW,Pournaras S,Meletiadis J

更新日期：2020-05-01 00:00:00

abstract：:This study investigated the molecular mechanisms of carbapenem resistance in clinical isolates of Klebsiella pneumoniae from Korea and the clinical outcomes of resistant K. pneumoniae infection. Sixteen K. pneumoniae isolates showing resistance to carbapenems collected from a tertiary-care hospital were examined for t...

journal_title：Journal of medical microbiology

authors： Shin SY,Bae IK,Kim J,Jeong SH,Yong D,Kim JM,Lee K

更新日期：2012-02-01 00:00:00

abstract：:Most past studies of cross-infection with Pseudomonas aeruginosa among cystic fibrosis (CF) patients in the UK suggest that it is a rare occurrence. However, two recent reports of highly transmissible strains in patients in regional centres in England (Liverpool and Manchester) have raised questions as to the extent o...

journal_title：Journal of medical microbiology

authors： Scott FW,Pitt TL

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:Extensively drug-resistant (XDR) strains of Acinetobacter baumannii are being reported worldwide, and they are associated with high morbidity and mortality rates. These strains are considered to be the highest priority for the development of new antibacterial agents. Therefore, we aimed to develop an effective ...

journal_title：Journal of medical microbiology

authors： Wintachai P,Naknaen A,Pomwised R,Voravuthikunchai SP,Smith DR

更新日期：2019-07-01 00:00:00

abstract：:Most hospital bacteriologists have divided staphylococci into two groups: Staphylococcus aureus and the coagulase-negative staphylococci of which the novobiocin-resistant varieties are termed S. saprophyticus. The identification of S. aureus has been easy but that of the other staphylococci has provided some difficult...

journal_title：Journal of medical microbiology

authors： Reuther JW

更新日期：1986-09-01 00:00:00