Modulation of actA gene expression in Listeria monocytogenes by iron.

Abstract:

:This study analysed the invasiveness of Listeria monocytogenes into enterocyte-like Caco-2 cells in which iron depletion was achieved by picolinic acid treatment. Both entry and intracellular multiplication varied depending on the endogenous iron content of bacterial and eukaryotic cells. The behaviour within enterocytes was correlated with a 10-fold increased transcription of the actA gene observed in bacterial cells grown under conditions of iron stress.

journal_name

J Med Microbiol

authors

Conte MP,Longhi C,Petrone G,Polidoro M,Valenti P,Seganti L

doi

10.1099/0022-1317-49-8-681

keywords:

subject

Has Abstract

pub_date

2000-08-01 00:00:00

pages

681-683

issue

8

eissn

0022-2615

issn

1473-5644

journal_volume

49

pub_type

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