Sleep-related disorders in Latin-American children with atopic dermatitis: A case control study.

Abstract:

BACKGROUND:Atopic dermatitis (AD) has been associated with impairment of sleep. The aim of this study was to evaluate sleep disorders in AD Latin-American children (4-10 years) from nine countries, and in normal controls (C). METHODS:Parents from 454 C and 340 AD children from referral clinics answered the Children Sleep Habits Questionnaire (CSHQ), a one-week retrospective 33 questions survey under seven items (bedtime resistance, sleep duration, sleep anxiety, night awakening, parasomnias, sleep-disordered breathing and daytime sleepiness). Total CSHQ score and items were analysed in both C and AD groups. Spearman's correlation coefficient between SCORAD (Scoring atopic dermatitis), all subscales and total CSHQ were also obtained. RESULTS:C and AD groups were similar regarding age, however, significantly higher values for total CSHQ (62.2±16.1 vs 53.3±12.7, respectively) and items were observed among AD children in comparison to C, and they were higher among those with moderate (54.8%) or severe (4.3%) AD. Except for sleep duration (r=-0.02, p=0.698), there was a significant Spearman's correlation index for bedtime resistance (0.24, p<0.0001), sleep anxiety (0.29, p<0.0001), night awakening (0.36, p<0.0001), parasomnias (0.54, p<0.0001), sleep-disordered breathing (0.42, p<0.0001), daytime sleepiness (0.26, p<0.0001) and total CSHQ (0.46, p<0.0001). AD patients had significantly higher elevated body mass index. CONCLUSION:Latin-American children with AD have sleep disorders despite treatment, and those with moderate to severe forms had marked changes in CSHQ.

authors

Urrutia-Pereira M,Solé D,Rosario NA,Neto HJC,Acosta V,Almendarez CF,Avalos MM,Badellino H,Berroa F,Álvarez-Castelló M,Castillo AJ,Castro-Almarales RL,De la Cruz MM,Cepeda AM,Fernandez C,González-León M,Lozano-Saenz J,Sa

doi

10.1016/j.aller.2016.08.014

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

276-282

issue

3

eissn

0301-0546

issn

1578-1267

pii

S0301-0546(16)30149-5

journal_volume

45

pub_type

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